Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_MITOTIC_G2_G2_M_PHASES |
| Enrichment Score (ES) | -0.46617642 |
| Normalized Enrichment Score (NES) | -2.489399 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HAUS7 | ENSG00000213397.10 | 1436 | 0.783 | -0.0217 | No | ||
| 2 | PHLDA1 | ENSG00000139289.13 | 2729 | 0.630 | -0.0426 | No | ||
| 3 | CDK5RAP2 | ENSG00000136861.18 | 3658 | 0.560 | -0.0557 | No | ||
| 4 | TUBGCP6 | ENSG00000128159.12 | 3674 | 0.559 | -0.0465 | No | ||
| 5 | NINL | ENSG00000101004.15 | 3818 | 0.548 | -0.0407 | No | ||
| 6 | HAUS5 | ENSG00000249115.9 | 5985 | 0.434 | -0.0862 | No | ||
| 7 | CEP131 | ENSG00000141577.14 | 6755 | 0.398 | -0.0982 | No | ||
| 8 | FBXL7 | ENSG00000183580.10 | 7650 | 0.365 | -0.1138 | No | ||
| 9 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1194 | No | ||
| 10 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.1768 | No | ||
| 11 | PRKAR2B | ENSG00000005249.13 | 12170 | 0.265 | -0.2083 | No | ||
| 12 | CSNK1E | ENSG00000213923.12 | 12504 | 0.254 | -0.2121 | No | ||
| 13 | SFI1 | ENSG00000198089.16 | 13183 | 0.233 | -0.2247 | No | ||
| 14 | CNTRL | ENSG00000119397.16 | 13560 | 0.220 | -0.2302 | No | ||
| 15 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2388 | No | ||
| 16 | CDK11B | ENSG00000248333.8 | 14919 | 0.176 | -0.2568 | No | ||
| 17 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.2710 | No | ||
| 18 | CDC25B | ENSG00000101224.17 | 15629 | 0.156 | -0.2688 | No | ||
| 19 | ODF2 | ENSG00000136811.16 | 15981 | 0.146 | -0.2749 | No | ||
| 20 | CEP135 | ENSG00000174799.11 | 16064 | 0.144 | -0.2745 | No | ||
| 21 | LCMT1 | ENSG00000205629.12 | 16829 | 0.122 | -0.2910 | No | ||
| 22 | FBXL18 | ENSG00000155034.19 | 16922 | 0.119 | -0.2913 | No | ||
| 23 | CEP192 | ENSG00000101639.18 | 17033 | 0.117 | -0.2920 | No | ||
| 24 | CEP57 | ENSG00000166037.11 | 17042 | 0.117 | -0.2902 | No | ||
| 25 | CEP164 | ENSG00000110274.16 | 17447 | 0.105 | -0.2982 | No | ||
| 26 | CCNA1 | ENSG00000133101.10 | 17734 | 0.098 | -0.3035 | No | ||
| 27 | RBBP4 | ENSG00000162521.19 | 18441 | 0.081 | -0.3194 | No | ||
| 28 | MZT2A | ENSG00000173272.16 | 18519 | 0.078 | -0.3199 | No | ||
| 29 | CSNK1D | ENSG00000141551.14 | 18935 | 0.067 | -0.3289 | No | ||
| 30 | HAUS1 | ENSG00000152240.13 | 19046 | 0.064 | -0.3305 | No | ||
| 31 | AKAP9 | ENSG00000127914.16 | 19199 | 0.060 | -0.3332 | No | ||
| 32 | HAUS3 | ENSG00000214367.8 | 19258 | 0.058 | -0.3337 | No | ||
| 33 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.3331 | No | ||
| 34 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3324 | No | ||
| 35 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.3342 | No | ||
| 36 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.3373 | No | ||
| 37 | TUBGCP4 | ENSG00000137822.12 | 19592 | 0.049 | -0.3372 | No | ||
| 38 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.3449 | No | ||
| 39 | MZT2B | ENSG00000152082.14 | 20114 | 0.036 | -0.3486 | No | ||
| 40 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.3652 | No | ||
| 41 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.3684 | No | ||
| 42 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.3688 | No | ||
| 43 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.3723 | No | ||
| 44 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.3761 | No | ||
| 45 | CDKN1A | ENSG00000124762.13 | 21297 | 0.004 | -0.3763 | No | ||
| 46 | FGFR1OP | ENSG00000213066.13 | 21442 | 0.000 | -0.3798 | No | ||
| 47 | FKBPL | ENSG00000204315.4 | 21467 | 0.000 | -0.3804 | No | ||
| 48 | EP300 | ENSG00000100393.13 | 21602 | -0.004 | -0.3836 | No | ||
| 49 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.3965 | No | ||
| 50 | OFD1 | ENSG00000046651.15 | 22172 | -0.017 | -0.3969 | No | ||
| 51 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.3986 | No | ||
| 52 | TUBGCP2 | ENSG00000130640.13 | 22760 | -0.032 | -0.4103 | No | ||
| 53 | DCTN3 | ENSG00000137100.16 | 22796 | -0.033 | -0.4106 | No | ||
| 54 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4150 | No | ||
| 55 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4156 | No | ||
| 56 | CEP70 | ENSG00000114107.9 | 23190 | -0.045 | -0.4180 | No | ||
| 57 | CEP76 | ENSG00000101624.11 | 23293 | -0.047 | -0.4197 | No | ||
| 58 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4199 | No | ||
| 59 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4193 | No | ||
| 60 | LIN37 | ENSG00000267796.8 | 23851 | -0.062 | -0.4306 | No | ||
| 61 | PCNT | ENSG00000160299.17 | 23855 | -0.062 | -0.4296 | No | ||
| 62 | NDE1 | ENSG00000072864.15 | 23985 | -0.064 | -0.4316 | No | ||
| 63 | CEP41 | ENSG00000106477.19 | 24138 | -0.068 | -0.4342 | No | ||
| 64 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4352 | No | ||
| 65 | ALMS1 | ENSG00000116127.18 | 24464 | -0.076 | -0.4396 | No | ||
| 66 | PRKACA | ENSG00000072062.14 | 24521 | -0.077 | -0.4397 | No | ||
| 67 | CUL1 | ENSG00000055130.17 | 24550 | -0.079 | -0.4390 | No | ||
| 68 | SSNA1 | ENSG00000176101.12 | 24700 | -0.083 | -0.4412 | No | ||
| 69 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.4411 | No | ||
| 70 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.4408 | No | ||
| 71 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.4565 | No | ||
| 72 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.4594 | No | ||
| 73 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.4598 | No | ||
| 74 | BTRC | ENSG00000166167.18 | 25965 | -0.119 | -0.4614 | No | ||
| 75 | TUBGCP5 | ENSG00000275835.5 | 25978 | -0.120 | -0.4597 | No | ||
| 76 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.4634 | Yes | ||
| 77 | CENPJ | ENSG00000151849.15 | 26281 | -0.128 | -0.4627 | Yes | ||
| 78 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.4612 | Yes | ||
| 79 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.4593 | Yes | ||
| 80 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.4602 | Yes | ||
| 81 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.4582 | Yes | ||
| 82 | HAUS8 | ENSG00000131351.15 | 26530 | -0.136 | -0.4574 | Yes | ||
| 83 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.4551 | Yes | ||
| 84 | HAUS4 | ENSG00000092036.18 | 26579 | -0.137 | -0.4539 | Yes | ||
| 85 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.4537 | Yes | ||
| 86 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.4548 | Yes | ||
| 87 | PPME1 | ENSG00000214517.10 | 26996 | -0.149 | -0.4566 | Yes | ||
| 88 | TP53 | ENSG00000141510.17 | 27245 | -0.156 | -0.4600 | Yes | ||
| 89 | PPP1R12B | ENSG00000077157.22 | 27498 | -0.164 | -0.4634 | Yes | ||
| 90 | PPP2R2A | ENSG00000221914.11 | 27524 | -0.165 | -0.4612 | Yes | ||
| 91 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.4606 | Yes | ||
| 92 | PCM1 | ENSG00000078674.17 | 27675 | -0.170 | -0.4591 | Yes | ||
| 93 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.4572 | Yes | ||
| 94 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.4553 | Yes | ||
| 95 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.4539 | Yes | ||
| 96 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4540 | Yes | ||
| 97 | CLASP1 | ENSG00000074054.18 | 28043 | -0.182 | -0.4530 | Yes | ||
| 98 | TUBGCP3 | ENSG00000126216.15 | 28303 | -0.190 | -0.4561 | Yes | ||
| 99 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.4557 | Yes | ||
| 100 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.4530 | Yes | ||
| 101 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.4539 | Yes | ||
| 102 | CCNH | ENSG00000134480.15 | 28769 | -0.204 | -0.4539 | Yes | ||
| 103 | HSP90AB1 | ENSG00000096384.20 | 28800 | -0.205 | -0.4511 | Yes | ||
| 104 | SKP1 | ENSG00000113558.18 | 28827 | -0.206 | -0.4482 | Yes | ||
| 105 | RAB8A | ENSG00000167461.12 | 29225 | -0.218 | -0.4542 | Yes | ||
| 106 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.4530 | Yes | ||
| 107 | TUBG2 | ENSG00000037042.9 | 29437 | -0.226 | -0.4517 | Yes | ||
| 108 | AJUBA | ENSG00000129474.16 | 29753 | -0.236 | -0.4554 | Yes | ||
| 109 | CEP72 | ENSG00000112877.8 | 29993 | -0.243 | -0.4571 | Yes | ||
| 110 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.4531 | Yes | ||
| 111 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.4515 | Yes | ||
| 112 | SDCCAG8 | ENSG00000054282.16 | 30251 | -0.252 | -0.4507 | Yes | ||
| 113 | CEP63 | ENSG00000182923.17 | 30525 | -0.260 | -0.4529 | Yes | ||
| 114 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.4530 | Yes | ||
| 115 | LIN54 | ENSG00000189308.11 | 30719 | -0.267 | -0.4485 | Yes | ||
| 116 | PPP2R1B | ENSG00000137713.16 | 30954 | -0.276 | -0.4495 | Yes | ||
| 117 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.4484 | Yes | ||
| 118 | CDK11A | ENSG00000008128.23 | 31169 | -0.284 | -0.4451 | Yes | ||
| 119 | PSMA8 | ENSG00000154611.14 | 31324 | -0.285 | -0.4440 | Yes | ||
| 120 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.4512 | Yes | ||
| 121 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.4563 | Yes | ||
| 122 | YWHAG | ENSG00000170027.7 | 32308 | -0.310 | -0.4525 | Yes | ||
| 123 | PPP2CA | ENSG00000113575.10 | 32408 | -0.314 | -0.4496 | Yes | ||
| 124 | RBX1 | ENSG00000100387.9 | 32483 | -0.316 | -0.4461 | Yes | ||
| 125 | NME7 | ENSG00000143156.14 | 32495 | -0.316 | -0.4409 | Yes | ||
| 126 | CEP78 | ENSG00000148019.13 | 32557 | -0.319 | -0.4370 | Yes | ||
| 127 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.4348 | Yes | ||
| 128 | LIN52 | ENSG00000205659.10 | 32727 | -0.325 | -0.4301 | Yes | ||
| 129 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.4252 | Yes | ||
| 130 | DCTN2 | ENSG00000175203.15 | 32923 | -0.333 | -0.4236 | Yes | ||
| 131 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.4242 | Yes | ||
| 132 | FOXM1 | ENSG00000111206.12 | 34188 | -0.349 | -0.4428 | Yes | ||
| 133 | PPP2R1A | ENSG00000105568.18 | 34725 | -0.357 | -0.4498 | Yes | ||
| 134 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.4512 | Yes | ||
| 135 | CEP250 | ENSG00000126001.16 | 35181 | -0.373 | -0.4483 | Yes | ||
| 136 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.4446 | Yes | ||
| 137 | MNAT1 | ENSG00000020426.11 | 35332 | -0.380 | -0.4390 | Yes | ||
| 138 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.4348 | Yes | ||
| 139 | FBXW11 | ENSG00000072803.17 | 35526 | -0.390 | -0.4305 | Yes | ||
| 140 | CCP110 | ENSG00000103540.16 | 35632 | -0.395 | -0.4264 | Yes | ||
| 141 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.4198 | Yes | ||
| 142 | DCTN1 | ENSG00000204843.12 | 35697 | -0.397 | -0.4144 | Yes | ||
| 143 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.4137 | Yes | ||
| 144 | CDC25C | ENSG00000158402.20 | 35954 | -0.403 | -0.4069 | Yes | ||
| 145 | PAFAH1B1 | ENSG00000007168.13 | 36076 | -0.408 | -0.4029 | Yes | ||
| 146 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.3978 | Yes | ||
| 147 | PPP1CB | ENSG00000213639.10 | 36325 | -0.417 | -0.3949 | Yes | ||
| 148 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.3900 | Yes | ||
| 149 | YWHAE | ENSG00000108953.17 | 36492 | -0.426 | -0.3845 | Yes | ||
| 150 | CCNB2 | ENSG00000157456.8 | 36613 | -0.432 | -0.3800 | Yes | ||
| 151 | PLK1 | ENSG00000166851.15 | 36707 | -0.436 | -0.3749 | Yes | ||
| 152 | HAUS2 | ENSG00000137814.11 | 36796 | -0.439 | -0.3696 | Yes | ||
| 153 | ACTR1A | ENSG00000138107.13 | 36970 | -0.450 | -0.3661 | Yes | ||
| 154 | MAPRE1 | ENSG00000101367.9 | 37101 | -0.458 | -0.3615 | Yes | ||
| 155 | NEDD1 | ENSG00000139350.11 | 37180 | -0.462 | -0.3556 | Yes | ||
| 156 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.3488 | Yes | ||
| 157 | LIN9 | ENSG00000183814.15 | 37237 | -0.466 | -0.3411 | Yes | ||
| 158 | CEP152 | ENSG00000103995.14 | 37402 | -0.478 | -0.3369 | Yes | ||
| 159 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3290 | Yes | ||
| 160 | HMMR | ENSG00000072571.20 | 37412 | -0.479 | -0.3208 | Yes | ||
| 161 | PKMYT1 | ENSG00000127564.17 | 37418 | -0.479 | -0.3128 | Yes | ||
| 162 | BORA | ENSG00000136122.17 | 37603 | -0.494 | -0.3089 | Yes | ||
| 163 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.3033 | Yes | ||
| 164 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.2967 | Yes | ||
| 165 | HSP90AA1 | ENSG00000080824.18 | 37823 | -0.514 | -0.2881 | Yes | ||
| 166 | CDK7 | ENSG00000134058.12 | 37950 | -0.524 | -0.2823 | Yes | ||
| 167 | NEK2 | ENSG00000117650.13 | 37958 | -0.525 | -0.2735 | Yes | ||
| 168 | PSME4 | ENSG00000068878.15 | 38072 | -0.532 | -0.2672 | Yes | ||
| 169 | E2F1 | ENSG00000101412.13 | 38085 | -0.533 | -0.2585 | Yes | ||
| 170 | CETN2 | ENSG00000147400.9 | 38135 | -0.537 | -0.2505 | Yes | ||
| 171 | CCNB1 | ENSG00000134057.15 | 38169 | -0.540 | -0.2421 | Yes | ||
| 172 | HAUS6 | ENSG00000147874.11 | 38210 | -0.543 | -0.2339 | Yes | ||
| 173 | TUBG1 | ENSG00000131462.8 | 38291 | -0.550 | -0.2264 | Yes | ||
| 174 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2176 | Yes | ||
| 175 | GTSE1 | ENSG00000075218.19 | 38414 | -0.557 | -0.2105 | Yes | ||
| 176 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2054 | Yes | ||
| 177 | CEP290 | ENSG00000198707.16 | 38626 | -0.564 | -0.1965 | Yes | ||
| 178 | AURKA | ENSG00000087586.17 | 38638 | -0.565 | -0.1871 | Yes | ||
| 179 | TPX2 | ENSG00000088325.16 | 38681 | -0.569 | -0.1785 | Yes | ||
| 180 | PPP2CB | ENSG00000104695.13 | 38708 | -0.572 | -0.1694 | Yes | ||
| 181 | TUBB | ENSG00000196230.13 | 39081 | -0.611 | -0.1681 | Yes | ||
| 182 | PLK4 | ENSG00000142731.11 | 39267 | -0.620 | -0.1620 | Yes | ||
| 183 | CENPF | ENSG00000117724.13 | 39444 | -0.631 | -0.1556 | Yes | ||
| 184 | CDK1 | ENSG00000170312.16 | 39453 | -0.632 | -0.1451 | Yes | ||
| 185 | OPTN | ENSG00000123240.17 | 39634 | -0.651 | -0.1384 | Yes | ||
| 186 | MZT1 | ENSG00000204899.6 | 39731 | -0.665 | -0.1294 | Yes | ||
| 187 | MYBL2 | ENSG00000101057.16 | 39815 | -0.677 | -0.1199 | Yes | ||
| 188 | WEE1 | ENSG00000166483.11 | 40002 | -0.714 | -0.1123 | Yes | ||
| 189 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.1024 | Yes | ||
| 190 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.0899 | Yes | ||
| 191 | PPP1R12A | ENSG00000058272.19 | 40248 | -0.765 | -0.0803 | Yes | ||
| 192 | CDC25A | ENSG00000164045.12 | 40263 | -0.768 | -0.0676 | Yes | ||
| 193 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.0545 | Yes | ||
| 194 | E2F3 | ENSG00000112242.15 | 40268 | -0.769 | -0.0415 | Yes | ||
| 195 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0331 | Yes | ||
| 196 | CCNA2 | ENSG00000145386.10 | 40598 | -0.874 | -0.0203 | Yes | ||
| 197 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | -0.0089 | Yes | ||
| 198 | PSMB11 | ENSG00000222028.5 | 40874 | -1.018 | 0.0070 | Yes |
