Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE |
| Enrichment Score (ES) | -0.5345459 |
| Normalized Enrichment Score (NES) | -2.8941016 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ANAPC2 | ENSG00000176248.9 | 6153 | 0.426 | -0.1434 | No | ||
| 2 | ANAPC5 | ENSG00000089053.13 | 6368 | 0.414 | -0.1421 | No | ||
| 3 | DYNC1I1 | ENSG00000158560.14 | 7076 | 0.386 | -0.1532 | No | ||
| 4 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1732 | No | ||
| 5 | RCC2 | ENSG00000179051.14 | 9112 | 0.331 | -0.1919 | No | ||
| 6 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.2257 | No | ||
| 7 | CENPP | ENSG00000188312.14 | 10894 | 0.295 | -0.2259 | No | ||
| 8 | LEMD2 | ENSG00000161904.12 | 11807 | 0.278 | -0.2438 | No | ||
| 9 | ITGB3BP | ENSG00000142856.16 | 13741 | 0.215 | -0.2875 | No | ||
| 10 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2920 | No | ||
| 11 | B9D2 | ENSG00000123810.8 | 14121 | 0.202 | -0.2903 | No | ||
| 12 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.3241 | No | ||
| 13 | RPS27 | ENSG00000177954.14 | 15622 | 0.156 | -0.3219 | No | ||
| 14 | RANGAP1 | ENSG00000100401.19 | 15733 | 0.152 | -0.3222 | No | ||
| 15 | CENPC | ENSG00000145241.11 | 15881 | 0.148 | -0.3235 | No | ||
| 16 | CDC26 | ENSG00000176386.9 | 15890 | 0.148 | -0.3213 | No | ||
| 17 | PDS5B | ENSG00000083642.19 | 16191 | 0.140 | -0.3264 | No | ||
| 18 | LEMD3 | ENSG00000174106.3 | 16219 | 0.139 | -0.3248 | No | ||
| 19 | PPP2R5A | ENSG00000066027.12 | 16937 | 0.118 | -0.3405 | No | ||
| 20 | PMF1 | ENSG00000160783.19 | 17911 | 0.093 | -0.3627 | No | ||
| 21 | RAD21 | ENSG00000164754.14 | 18730 | 0.073 | -0.3816 | No | ||
| 22 | NUP160 | ENSG00000030066.13 | 18845 | 0.069 | -0.3832 | No | ||
| 23 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.3928 | No | ||
| 24 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3922 | No | ||
| 25 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.3941 | No | ||
| 26 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.3972 | No | ||
| 27 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.4057 | No | ||
| 28 | NUP43 | ENSG00000120253.14 | 20047 | 0.038 | -0.4077 | No | ||
| 29 | CENPT | ENSG00000102901.13 | 20096 | 0.037 | -0.4083 | No | ||
| 30 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.4255 | No | ||
| 31 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.4286 | No | ||
| 32 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.4290 | No | ||
| 33 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.4326 | No | ||
| 34 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.4363 | No | ||
| 35 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.4571 | No | ||
| 36 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.4594 | No | ||
| 37 | SEC13 | ENSG00000157020.18 | 22468 | -0.026 | -0.4642 | No | ||
| 38 | NDEL1 | ENSG00000166579.15 | 22882 | -0.036 | -0.4737 | No | ||
| 39 | BANF1 | ENSG00000175334.8 | 22894 | -0.036 | -0.4734 | No | ||
| 40 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4754 | No | ||
| 41 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4761 | No | ||
| 42 | DYNLL2 | ENSG00000264364.3 | 23336 | -0.048 | -0.4821 | No | ||
| 43 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4813 | No | ||
| 44 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4808 | No | ||
| 45 | NUDC | ENSG00000090273.14 | 23568 | -0.054 | -0.4853 | No | ||
| 46 | SEH1L | ENSG00000085415.16 | 23768 | -0.059 | -0.4892 | No | ||
| 47 | NDE1 | ENSG00000072864.15 | 23985 | -0.064 | -0.4934 | No | ||
| 48 | ANAPC1 | ENSG00000153107.13 | 24092 | -0.067 | -0.4950 | No | ||
| 49 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4972 | No | ||
| 50 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.5086 | No | ||
| 51 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.5084 | No | ||
| 52 | NUP133 | ENSG00000069248.12 | 24802 | -0.086 | -0.5070 | No | ||
| 53 | PPP2R5D | ENSG00000112640.15 | 24932 | -0.090 | -0.5087 | No | ||
| 54 | MIS12 | ENSG00000167842.15 | 25231 | -0.097 | -0.5145 | No | ||
| 55 | NSL1 | ENSG00000117697.15 | 25239 | -0.097 | -0.5131 | No | ||
| 56 | DYNC1LI2 | ENSG00000135720.13 | 25352 | -0.101 | -0.5142 | No | ||
| 57 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.5166 | No | ||
| 58 | HDAC8 | ENSG00000147099.21 | 25669 | -0.110 | -0.5185 | No | ||
| 59 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.5179 | No | ||
| 60 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.5184 | No | ||
| 61 | ANAPC10 | ENSG00000164162.14 | 26104 | -0.124 | -0.5235 | No | ||
| 62 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.5243 | No | ||
| 63 | ANAPC7 | ENSG00000196510.12 | 26263 | -0.128 | -0.5233 | No | ||
| 64 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.5224 | No | ||
| 65 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.5206 | No | ||
| 66 | ANKLE2 | ENSG00000176915.15 | 26359 | -0.131 | -0.5194 | No | ||
| 67 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.5195 | No | ||
| 68 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.5177 | No | ||
| 69 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.5171 | No | ||
| 70 | ANAPC11 | ENSG00000141552.17 | 26543 | -0.136 | -0.5152 | No | ||
| 71 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.5160 | No | ||
| 72 | ANAPC4 | ENSG00000053900.10 | 26737 | -0.142 | -0.5154 | No | ||
| 73 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.5150 | No | ||
| 74 | NUP107 | ENSG00000111581.10 | 26867 | -0.145 | -0.5139 | No | ||
| 75 | PPP2R5E | ENSG00000154001.14 | 27182 | -0.155 | -0.5191 | No | ||
| 76 | PPP2R2A | ENSG00000221914.11 | 27524 | -0.165 | -0.5248 | No | ||
| 77 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.5245 | No | ||
| 78 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.5241 | No | ||
| 79 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.5224 | No | ||
| 80 | NUP85 | ENSG00000125450.11 | 27774 | -0.173 | -0.5200 | No | ||
| 81 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.5185 | No | ||
| 82 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.5187 | No | ||
| 83 | CLASP1 | ENSG00000074054.18 | 28043 | -0.182 | -0.5179 | No | ||
| 84 | NUP98 | ENSG00000110713.17 | 28185 | -0.186 | -0.5184 | No | ||
| 85 | STAG1 | ENSG00000118007.13 | 28245 | -0.188 | -0.5169 | No | ||
| 86 | CLASP2 | ENSG00000163539.17 | 28270 | -0.189 | -0.5145 | No | ||
| 87 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.5152 | No | ||
| 88 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.5126 | No | ||
| 89 | PPP1CC | ENSG00000186298.12 | 28475 | -0.195 | -0.5101 | No | ||
| 90 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.5106 | No | ||
| 91 | ANAPC16 | ENSG00000166295.9 | 29001 | -0.212 | -0.5164 | No | ||
| 92 | EMD | ENSG00000102119.10 | 29246 | -0.219 | -0.5188 | No | ||
| 93 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.5173 | No | ||
| 94 | CDC27 | ENSG00000004897.12 | 29738 | -0.236 | -0.5235 | No | ||
| 95 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.5261 | No | ||
| 96 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.5247 | No | ||
| 97 | CDC23 | ENSG00000094880.11 | 30249 | -0.252 | -0.5241 | No | ||
| 98 | PPP2R5C | ENSG00000078304.19 | 30677 | -0.265 | -0.5303 | Yes | ||
| 99 | UBE2D1 | ENSG00000072401.15 | 30679 | -0.265 | -0.5262 | Yes | ||
| 100 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.5228 | Yes | ||
| 101 | ZW10 | ENSG00000086827.9 | 30856 | -0.271 | -0.5219 | Yes | ||
| 102 | PPP2R1B | ENSG00000137713.16 | 30954 | -0.276 | -0.5199 | Yes | ||
| 103 | PPP2R5B | ENSG00000068971.14 | 31101 | -0.281 | -0.5190 | Yes | ||
| 104 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.5146 | Yes | ||
| 105 | PSMA8 | ENSG00000154611.14 | 31324 | -0.285 | -0.5154 | Yes | ||
| 106 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.5229 | Yes | ||
| 107 | PDS5A | ENSG00000121892.15 | 31964 | -0.295 | -0.5216 | Yes | ||
| 108 | PTTG1 | ENSG00000164611.13 | 31965 | -0.295 | -0.5169 | Yes | ||
| 109 | BUB3 | ENSG00000154473.18 | 32087 | -0.300 | -0.5151 | Yes | ||
| 110 | INCENP | ENSG00000149503.13 | 32126 | -0.301 | -0.5113 | Yes | ||
| 111 | CENPQ | ENSG00000031691.7 | 32142 | -0.302 | -0.5068 | Yes | ||
| 112 | CENPO | ENSG00000138092.11 | 32352 | -0.312 | -0.5070 | Yes | ||
| 113 | CENPU | ENSG00000151725.12 | 32395 | -0.313 | -0.5030 | Yes | ||
| 114 | PPP2CA | ENSG00000113575.10 | 32408 | -0.314 | -0.4983 | Yes | ||
| 115 | NUF2 | ENSG00000143228.13 | 32503 | -0.317 | -0.4956 | Yes | ||
| 116 | RANBP2 | ENSG00000153201.16 | 32550 | -0.318 | -0.4917 | Yes | ||
| 117 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.4900 | Yes | ||
| 118 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.4863 | Yes | ||
| 119 | AHCTF1 | ENSG00000153207.15 | 32851 | -0.330 | -0.4834 | Yes | ||
| 120 | TMPO | ENSG00000120802.13 | 32905 | -0.332 | -0.4794 | Yes | ||
| 121 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.4809 | Yes | ||
| 122 | VRK2 | ENSG00000028116.17 | 34103 | -0.345 | -0.4978 | Yes | ||
| 123 | DSN1 | ENSG00000149636.15 | 34130 | -0.346 | -0.4929 | Yes | ||
| 124 | CDC20 | ENSG00000117399.14 | 34187 | -0.349 | -0.4887 | Yes | ||
| 125 | LMNA | ENSG00000160789.20 | 34605 | -0.352 | -0.4933 | Yes | ||
| 126 | PPP2R1A | ENSG00000105568.18 | 34725 | -0.357 | -0.4905 | Yes | ||
| 127 | TAOK1 | ENSG00000160551.11 | 34732 | -0.358 | -0.4850 | Yes | ||
| 128 | SGO1 | ENSG00000129810.15 | 34782 | -0.360 | -0.4805 | Yes | ||
| 129 | STAG2 | ENSG00000101972.18 | 34834 | -0.363 | -0.4760 | Yes | ||
| 130 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.4751 | Yes | ||
| 131 | CENPH | ENSG00000153044.10 | 35190 | -0.373 | -0.4728 | Yes | ||
| 132 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.4693 | Yes | ||
| 133 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.4665 | Yes | ||
| 134 | CENPS | ENSG00000175279.22 | 35550 | -0.391 | -0.4632 | Yes | ||
| 135 | NUP37 | ENSG00000075188.9 | 35611 | -0.394 | -0.4584 | Yes | ||
| 136 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.4528 | Yes | ||
| 137 | CDC16 | ENSG00000130177.16 | 35800 | -0.402 | -0.4503 | Yes | ||
| 138 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.4475 | Yes | ||
| 139 | PAFAH1B1 | ENSG00000007168.13 | 36076 | -0.408 | -0.4441 | Yes | ||
| 140 | CENPK | ENSG00000123219.13 | 36086 | -0.408 | -0.4378 | Yes | ||
| 141 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.4329 | Yes | ||
| 142 | BIRC5 | ENSG00000089685.15 | 36279 | -0.415 | -0.4294 | Yes | ||
| 143 | ESPL1 | ENSG00000135476.11 | 36287 | -0.415 | -0.4229 | Yes | ||
| 144 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.4194 | Yes | ||
| 145 | WAPL | ENSG00000062650.19 | 36609 | -0.432 | -0.4172 | Yes | ||
| 146 | SPC24 | ENSG00000161888.11 | 36669 | -0.434 | -0.4117 | Yes | ||
| 147 | PLK1 | ENSG00000166851.15 | 36707 | -0.436 | -0.4057 | Yes | ||
| 148 | KIF2C | ENSG00000142945.13 | 36852 | -0.443 | -0.4022 | Yes | ||
| 149 | ANAPC15 | ENSG00000110200.8 | 36886 | -0.445 | -0.3959 | Yes | ||
| 150 | CENPN | ENSG00000166451.13 | 36906 | -0.447 | -0.3893 | Yes | ||
| 151 | SMC3 | ENSG00000108055.9 | 36921 | -0.447 | -0.3825 | Yes | ||
| 152 | KIF2A | ENSG00000068796.16 | 36994 | -0.452 | -0.3771 | Yes | ||
| 153 | SPC25 | ENSG00000152253.9 | 37054 | -0.455 | -0.3713 | Yes | ||
| 154 | MAPRE1 | ENSG00000101367.9 | 37101 | -0.458 | -0.3652 | Yes | ||
| 155 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.3608 | Yes | ||
| 156 | MAD1L1 | ENSG00000002822.15 | 37265 | -0.468 | -0.3543 | Yes | ||
| 157 | SPDL1 | ENSG00000040275.17 | 37361 | -0.475 | -0.3490 | Yes | ||
| 158 | UBE2E1 | ENSG00000170142.12 | 37384 | -0.477 | -0.3420 | Yes | ||
| 159 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3350 | Yes | ||
| 160 | AURKB | ENSG00000178999.13 | 37485 | -0.484 | -0.3291 | Yes | ||
| 161 | SKA1 | ENSG00000154839.10 | 37525 | -0.487 | -0.3223 | Yes | ||
| 162 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.3192 | Yes | ||
| 163 | BUB1 | ENSG00000169679.15 | 37763 | -0.508 | -0.3120 | Yes | ||
| 164 | FBXO5 | ENSG00000112029.10 | 37782 | -0.511 | -0.3043 | Yes | ||
| 165 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.2969 | Yes | ||
| 166 | MAD2L1 | ENSG00000164109.14 | 37893 | -0.520 | -0.2906 | Yes | ||
| 167 | SMC1A | ENSG00000072501.17 | 37922 | -0.522 | -0.2830 | Yes | ||
| 168 | NDC80 | ENSG00000080986.13 | 37927 | -0.522 | -0.2748 | Yes | ||
| 169 | CENPA | ENSG00000115163.15 | 37993 | -0.527 | -0.2680 | Yes | ||
| 170 | PSME4 | ENSG00000068878.15 | 38072 | -0.532 | -0.2614 | Yes | ||
| 171 | UBE2C | ENSG00000175063.17 | 38091 | -0.534 | -0.2534 | Yes | ||
| 172 | BUB1B | ENSG00000156970.12 | 38129 | -0.537 | -0.2457 | Yes | ||
| 173 | DYNC1LI1 | ENSG00000144635.9 | 38271 | -0.548 | -0.2405 | Yes | ||
| 174 | CENPL | ENSG00000120334.15 | 38315 | -0.553 | -0.2327 | Yes | ||
| 175 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2240 | Yes | ||
| 176 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2219 | Yes | ||
| 177 | CDCA8 | ENSG00000134690.11 | 38629 | -0.564 | -0.2136 | Yes | ||
| 178 | PPP2CB | ENSG00000104695.13 | 38708 | -0.572 | -0.2065 | Yes | ||
| 179 | CENPM | ENSG00000100162.15 | 38711 | -0.572 | -0.1974 | Yes | ||
| 180 | SKA2 | ENSG00000182628.13 | 38739 | -0.574 | -0.1889 | Yes | ||
| 181 | CDCA5 | ENSG00000146670.10 | 38957 | -0.596 | -0.1848 | Yes | ||
| 182 | SGO2 | ENSG00000163535.18 | 38980 | -0.599 | -0.1758 | Yes | ||
| 183 | ZWINT | ENSG00000122952.17 | 39173 | -0.616 | -0.1707 | Yes | ||
| 184 | CLIP1 | ENSG00000130779.20 | 39284 | -0.622 | -0.1635 | Yes | ||
| 185 | CENPF | ENSG00000117724.13 | 39444 | -0.631 | -0.1573 | Yes | ||
| 186 | LMNB1 | ENSG00000113368.12 | 39725 | -0.665 | -0.1536 | Yes | ||
| 187 | KNTC1 | ENSG00000184445.12 | 39875 | -0.690 | -0.1463 | Yes | ||
| 188 | VRK1 | ENSG00000100749.8 | 39936 | -0.701 | -0.1366 | Yes | ||
| 189 | ERCC6L | ENSG00000186871.7 | 39947 | -0.704 | -0.1257 | Yes | ||
| 190 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.1179 | Yes | ||
| 191 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.1063 | Yes | ||
| 192 | ZWILCH | ENSG00000174442.12 | 40134 | -0.739 | -0.0951 | Yes | ||
| 193 | KNL1 | ENSG00000137812.19 | 40136 | -0.739 | -0.0834 | Yes | ||
| 194 | CENPE | ENSG00000138778.12 | 40145 | -0.740 | -0.0718 | Yes | ||
| 195 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.0625 | Yes | ||
| 196 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0551 | Yes | ||
| 197 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | -0.0470 | Yes | ||
| 198 | PSMB11 | ENSG00000222028.5 | 40874 | -1.018 | -0.0322 | Yes | ||
| 199 | KIF18A | ENSG00000121621.7 | 40921 | -1.038 | -0.0168 | Yes | ||
| 200 | CENPI | ENSG00000102384.13 | 41099 | -1.425 | 0.0015 | Yes |
