Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_MITOTIC_PROMETAPHASE |
| Enrichment Score (ES) | -0.52850693 |
| Normalized Enrichment Score (NES) | -2.7832956 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HAUS7 | ENSG00000213397.10 | 1436 | 0.783 | -0.0233 | No | ||
| 2 | CDK5RAP2 | ENSG00000136861.18 | 3658 | 0.560 | -0.0691 | No | ||
| 3 | TUBGCP6 | ENSG00000128159.12 | 3674 | 0.559 | -0.0610 | No | ||
| 4 | NINL | ENSG00000101004.15 | 3818 | 0.548 | -0.0563 | No | ||
| 5 | NUMA1 | ENSG00000137497.17 | 5945 | 0.436 | -0.1016 | No | ||
| 6 | HAUS5 | ENSG00000249115.9 | 5985 | 0.434 | -0.0960 | No | ||
| 7 | CEP131 | ENSG00000141577.14 | 6755 | 0.398 | -0.1088 | No | ||
| 8 | DYNC1I1 | ENSG00000158560.14 | 7076 | 0.386 | -0.1108 | No | ||
| 9 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1311 | No | ||
| 10 | RCC2 | ENSG00000179051.14 | 9112 | 0.331 | -0.1501 | No | ||
| 11 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.1841 | No | ||
| 12 | CENPP | ENSG00000188312.14 | 10894 | 0.295 | -0.1846 | No | ||
| 13 | PRKAR2B | ENSG00000005249.13 | 12170 | 0.265 | -0.2117 | No | ||
| 14 | CSNK1E | ENSG00000213923.12 | 12504 | 0.254 | -0.2160 | No | ||
| 15 | SFI1 | ENSG00000198089.16 | 13183 | 0.233 | -0.2290 | No | ||
| 16 | CNTRL | ENSG00000119397.16 | 13560 | 0.220 | -0.2349 | No | ||
| 17 | ITGB3BP | ENSG00000142856.16 | 13741 | 0.215 | -0.2361 | No | ||
| 18 | B9D2 | ENSG00000123810.8 | 14121 | 0.202 | -0.2423 | No | ||
| 19 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.2762 | No | ||
| 20 | RPS27 | ENSG00000177954.14 | 15622 | 0.156 | -0.2742 | No | ||
| 21 | RANGAP1 | ENSG00000100401.19 | 15733 | 0.152 | -0.2746 | No | ||
| 22 | CENPC | ENSG00000145241.11 | 15881 | 0.148 | -0.2759 | No | ||
| 23 | ODF2 | ENSG00000136811.16 | 15981 | 0.146 | -0.2762 | No | ||
| 24 | CEP135 | ENSG00000174799.11 | 16064 | 0.144 | -0.2760 | No | ||
| 25 | PDS5B | ENSG00000083642.19 | 16191 | 0.140 | -0.2770 | No | ||
| 26 | PPP2R5A | ENSG00000066027.12 | 16937 | 0.118 | -0.2934 | No | ||
| 27 | CEP192 | ENSG00000101639.18 | 17033 | 0.117 | -0.2939 | No | ||
| 28 | CEP57 | ENSG00000166037.11 | 17042 | 0.117 | -0.2924 | No | ||
| 29 | CEP164 | ENSG00000110274.16 | 17447 | 0.105 | -0.3007 | No | ||
| 30 | PMF1 | ENSG00000160783.19 | 17911 | 0.093 | -0.3106 | No | ||
| 31 | MZT2A | ENSG00000173272.16 | 18519 | 0.078 | -0.3242 | No | ||
| 32 | RAD21 | ENSG00000164754.14 | 18730 | 0.073 | -0.3282 | No | ||
| 33 | NUP160 | ENSG00000030066.13 | 18845 | 0.069 | -0.3300 | No | ||
| 34 | CSNK1D | ENSG00000141551.14 | 18935 | 0.067 | -0.3311 | No | ||
| 35 | HAUS1 | ENSG00000152240.13 | 19046 | 0.064 | -0.3329 | No | ||
| 36 | CSNK2A2 | ENSG00000070770.9 | 19164 | 0.061 | -0.3348 | No | ||
| 37 | AKAP9 | ENSG00000127914.16 | 19199 | 0.060 | -0.3347 | No | ||
| 38 | HAUS3 | ENSG00000214367.8 | 19258 | 0.058 | -0.3353 | No | ||
| 39 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3352 | No | ||
| 40 | TUBGCP4 | ENSG00000137822.12 | 19592 | 0.049 | -0.3418 | No | ||
| 41 | NUP43 | ENSG00000120253.14 | 20047 | 0.038 | -0.3523 | No | ||
| 42 | CENPT | ENSG00000102901.13 | 20096 | 0.037 | -0.3529 | No | ||
| 43 | MZT2B | ENSG00000152082.14 | 20114 | 0.036 | -0.3528 | No | ||
| 44 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.3813 | No | ||
| 45 | FGFR1OP | ENSG00000213066.13 | 21442 | 0.000 | -0.3851 | No | ||
| 46 | SMC4 | ENSG00000113810.16 | 21685 | -0.006 | -0.3909 | No | ||
| 47 | OFD1 | ENSG00000046651.15 | 22172 | -0.017 | -0.4025 | No | ||
| 48 | SEC13 | ENSG00000157020.18 | 22468 | -0.026 | -0.4093 | No | ||
| 49 | TUBGCP2 | ENSG00000130640.13 | 22760 | -0.032 | -0.4159 | No | ||
| 50 | DCTN3 | ENSG00000137100.16 | 22796 | -0.033 | -0.4163 | No | ||
| 51 | NDEL1 | ENSG00000166579.15 | 22882 | -0.036 | -0.4178 | No | ||
| 52 | CEP70 | ENSG00000114107.9 | 23190 | -0.045 | -0.4247 | No | ||
| 53 | CEP76 | ENSG00000101624.11 | 23293 | -0.047 | -0.4264 | No | ||
| 54 | DYNLL2 | ENSG00000264364.3 | 23336 | -0.048 | -0.4268 | No | ||
| 55 | NUDC | ENSG00000090273.14 | 23568 | -0.054 | -0.4316 | No | ||
| 56 | CSNK2B | ENSG00000204435.13 | 23621 | -0.056 | -0.4320 | No | ||
| 57 | SEH1L | ENSG00000085415.16 | 23768 | -0.059 | -0.4347 | No | ||
| 58 | PCNT | ENSG00000160299.17 | 23855 | -0.062 | -0.4358 | No | ||
| 59 | NDE1 | ENSG00000072864.15 | 23985 | -0.064 | -0.4380 | No | ||
| 60 | CEP41 | ENSG00000106477.19 | 24138 | -0.068 | -0.4407 | No | ||
| 61 | ALMS1 | ENSG00000116127.18 | 24464 | -0.076 | -0.4475 | No | ||
| 62 | PRKACA | ENSG00000072062.14 | 24521 | -0.077 | -0.4477 | No | ||
| 63 | SSNA1 | ENSG00000176101.12 | 24700 | -0.083 | -0.4508 | No | ||
| 64 | NUP133 | ENSG00000069248.12 | 24802 | -0.086 | -0.4520 | No | ||
| 65 | NCAPD2 | ENSG00000010292.13 | 24848 | -0.087 | -0.4518 | No | ||
| 66 | PPP2R5D | ENSG00000112640.15 | 24932 | -0.090 | -0.4525 | No | ||
| 67 | MIS12 | ENSG00000167842.15 | 25231 | -0.097 | -0.4583 | No | ||
| 68 | NSL1 | ENSG00000117697.15 | 25239 | -0.097 | -0.4570 | No | ||
| 69 | DYNC1LI2 | ENSG00000135720.13 | 25352 | -0.101 | -0.4582 | No | ||
| 70 | HDAC8 | ENSG00000147099.21 | 25669 | -0.110 | -0.4643 | No | ||
| 71 | TUBGCP5 | ENSG00000275835.5 | 25978 | -0.120 | -0.4700 | No | ||
| 72 | CENPJ | ENSG00000151849.15 | 26281 | -0.128 | -0.4754 | No | ||
| 73 | HAUS8 | ENSG00000131351.15 | 26530 | -0.136 | -0.4794 | No | ||
| 74 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.4774 | No | ||
| 75 | HAUS4 | ENSG00000092036.18 | 26579 | -0.137 | -0.4765 | No | ||
| 76 | NUP107 | ENSG00000111581.10 | 26867 | -0.145 | -0.4813 | No | ||
| 77 | PPP2R5E | ENSG00000154001.14 | 27182 | -0.155 | -0.4866 | No | ||
| 78 | PCM1 | ENSG00000078674.17 | 27675 | -0.170 | -0.4961 | No | ||
| 79 | NUP85 | ENSG00000125450.11 | 27774 | -0.173 | -0.4959 | No | ||
| 80 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.4946 | No | ||
| 81 | CLASP1 | ENSG00000074054.18 | 28043 | -0.182 | -0.4970 | No | ||
| 82 | NUP98 | ENSG00000110713.17 | 28185 | -0.186 | -0.4977 | No | ||
| 83 | STAG1 | ENSG00000118007.13 | 28245 | -0.188 | -0.4963 | No | ||
| 84 | CLASP2 | ENSG00000163539.17 | 28270 | -0.189 | -0.4940 | No | ||
| 85 | TUBGCP3 | ENSG00000126216.15 | 28303 | -0.190 | -0.4920 | No | ||
| 86 | PPP1CC | ENSG00000186298.12 | 28475 | -0.195 | -0.4932 | No | ||
| 87 | CSNK2A1 | ENSG00000101266.19 | 29203 | -0.218 | -0.5077 | No | ||
| 88 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.5074 | No | ||
| 89 | TUBG2 | ENSG00000037042.9 | 29437 | -0.226 | -0.5066 | No | ||
| 90 | CEP72 | ENSG00000112877.8 | 29993 | -0.243 | -0.5165 | No | ||
| 91 | SDCCAG8 | ENSG00000054282.16 | 30251 | -0.252 | -0.5189 | No | ||
| 92 | CEP63 | ENSG00000182923.17 | 30525 | -0.260 | -0.5217 | No | ||
| 93 | PPP2R5C | ENSG00000078304.19 | 30677 | -0.265 | -0.5214 | No | ||
| 94 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.5183 | No | ||
| 95 | ZW10 | ENSG00000086827.9 | 30856 | -0.271 | -0.5176 | No | ||
| 96 | PPP2R1B | ENSG00000137713.16 | 30954 | -0.276 | -0.5158 | No | ||
| 97 | PPP2R5B | ENSG00000068971.14 | 31101 | -0.281 | -0.5152 | No | ||
| 98 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.5111 | No | ||
| 99 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.5241 | Yes | ||
| 100 | PDS5A | ENSG00000121892.15 | 31964 | -0.295 | -0.5231 | Yes | ||
| 101 | BUB3 | ENSG00000154473.18 | 32087 | -0.300 | -0.5216 | Yes | ||
| 102 | INCENP | ENSG00000149503.13 | 32126 | -0.301 | -0.5180 | Yes | ||
| 103 | CENPQ | ENSG00000031691.7 | 32142 | -0.302 | -0.5138 | Yes | ||
| 104 | YWHAG | ENSG00000170027.7 | 32308 | -0.310 | -0.5132 | Yes | ||
| 105 | CENPO | ENSG00000138092.11 | 32352 | -0.312 | -0.5096 | Yes | ||
| 106 | CENPU | ENSG00000151725.12 | 32395 | -0.313 | -0.5059 | Yes | ||
| 107 | PPP2CA | ENSG00000113575.10 | 32408 | -0.314 | -0.5014 | Yes | ||
| 108 | NME7 | ENSG00000143156.14 | 32495 | -0.316 | -0.4988 | Yes | ||
| 109 | NUF2 | ENSG00000143228.13 | 32503 | -0.317 | -0.4942 | Yes | ||
| 110 | RANBP2 | ENSG00000153201.16 | 32550 | -0.318 | -0.4905 | Yes | ||
| 111 | CEP78 | ENSG00000148019.13 | 32557 | -0.319 | -0.4859 | Yes | ||
| 112 | AHCTF1 | ENSG00000153207.15 | 32851 | -0.330 | -0.4881 | Yes | ||
| 113 | DCTN2 | ENSG00000175203.15 | 32923 | -0.333 | -0.4848 | Yes | ||
| 114 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.4861 | Yes | ||
| 115 | DSN1 | ENSG00000149636.15 | 34130 | -0.346 | -0.5039 | Yes | ||
| 116 | CDC20 | ENSG00000117399.14 | 34187 | -0.349 | -0.5000 | Yes | ||
| 117 | PPP2R1A | ENSG00000105568.18 | 34725 | -0.357 | -0.5078 | Yes | ||
| 118 | TAOK1 | ENSG00000160551.11 | 34732 | -0.358 | -0.5025 | Yes | ||
| 119 | SGO1 | ENSG00000129810.15 | 34782 | -0.360 | -0.4983 | Yes | ||
| 120 | STAG2 | ENSG00000101972.18 | 34834 | -0.363 | -0.4941 | Yes | ||
| 121 | CEP250 | ENSG00000126001.16 | 35181 | -0.373 | -0.4969 | Yes | ||
| 122 | CENPH | ENSG00000153044.10 | 35190 | -0.373 | -0.4915 | Yes | ||
| 123 | CENPS | ENSG00000175279.22 | 35550 | -0.391 | -0.4944 | Yes | ||
| 124 | NUP37 | ENSG00000075188.9 | 35611 | -0.394 | -0.4899 | Yes | ||
| 125 | CCP110 | ENSG00000103540.16 | 35632 | -0.395 | -0.4845 | Yes | ||
| 126 | DCTN1 | ENSG00000204843.12 | 35697 | -0.397 | -0.4801 | Yes | ||
| 127 | PAFAH1B1 | ENSG00000007168.13 | 36076 | -0.408 | -0.4832 | Yes | ||
| 128 | CENPK | ENSG00000123219.13 | 36086 | -0.408 | -0.4772 | Yes | ||
| 129 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.4726 | Yes | ||
| 130 | BIRC5 | ENSG00000089685.15 | 36279 | -0.415 | -0.4695 | Yes | ||
| 131 | YWHAE | ENSG00000108953.17 | 36492 | -0.426 | -0.4682 | Yes | ||
| 132 | WAPL | ENSG00000062650.19 | 36609 | -0.432 | -0.4646 | Yes | ||
| 133 | CCNB2 | ENSG00000157456.8 | 36613 | -0.432 | -0.4581 | Yes | ||
| 134 | SPC24 | ENSG00000161888.11 | 36669 | -0.434 | -0.4529 | Yes | ||
| 135 | PLK1 | ENSG00000166851.15 | 36707 | -0.436 | -0.4473 | Yes | ||
| 136 | HAUS2 | ENSG00000137814.11 | 36796 | -0.439 | -0.4428 | Yes | ||
| 137 | KIF2C | ENSG00000142945.13 | 36852 | -0.443 | -0.4375 | Yes | ||
| 138 | CENPN | ENSG00000166451.13 | 36906 | -0.447 | -0.4321 | Yes | ||
| 139 | SMC3 | ENSG00000108055.9 | 36921 | -0.447 | -0.4257 | Yes | ||
| 140 | ACTR1A | ENSG00000138107.13 | 36970 | -0.450 | -0.4201 | Yes | ||
| 141 | KIF2A | ENSG00000068796.16 | 36994 | -0.452 | -0.4138 | Yes | ||
| 142 | SPC25 | ENSG00000152253.9 | 37054 | -0.455 | -0.4084 | Yes | ||
| 143 | MAPRE1 | ENSG00000101367.9 | 37101 | -0.458 | -0.4027 | Yes | ||
| 144 | NEDD1 | ENSG00000139350.11 | 37180 | -0.462 | -0.3976 | Yes | ||
| 145 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.3917 | Yes | ||
| 146 | MAD1L1 | ENSG00000002822.15 | 37265 | -0.468 | -0.3856 | Yes | ||
| 147 | SPDL1 | ENSG00000040275.17 | 37361 | -0.475 | -0.3808 | Yes | ||
| 148 | CEP152 | ENSG00000103995.14 | 37402 | -0.478 | -0.3745 | Yes | ||
| 149 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3675 | Yes | ||
| 150 | AURKB | ENSG00000178999.13 | 37485 | -0.484 | -0.3620 | Yes | ||
| 151 | SKA1 | ENSG00000154839.10 | 37525 | -0.487 | -0.3557 | Yes | ||
| 152 | BUB1 | ENSG00000169679.15 | 37763 | -0.508 | -0.3538 | Yes | ||
| 153 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.3473 | Yes | ||
| 154 | HSP90AA1 | ENSG00000080824.18 | 37823 | -0.514 | -0.3397 | Yes | ||
| 155 | MAD2L1 | ENSG00000164109.14 | 37893 | -0.520 | -0.3336 | Yes | ||
| 156 | SMC1A | ENSG00000072501.17 | 37922 | -0.522 | -0.3264 | Yes | ||
| 157 | NDC80 | ENSG00000080986.13 | 37927 | -0.522 | -0.3187 | Yes | ||
| 158 | NEK2 | ENSG00000117650.13 | 37958 | -0.525 | -0.3115 | Yes | ||
| 159 | CENPA | ENSG00000115163.15 | 37993 | -0.527 | -0.3044 | Yes | ||
| 160 | BUB1B | ENSG00000156970.12 | 38129 | -0.537 | -0.2996 | Yes | ||
| 161 | CETN2 | ENSG00000147400.9 | 38135 | -0.537 | -0.2917 | Yes | ||
| 162 | CCNB1 | ENSG00000134057.15 | 38169 | -0.540 | -0.2844 | Yes | ||
| 163 | HAUS6 | ENSG00000147874.11 | 38210 | -0.543 | -0.2772 | Yes | ||
| 164 | DYNC1LI1 | ENSG00000144635.9 | 38271 | -0.548 | -0.2704 | Yes | ||
| 165 | TUBG1 | ENSG00000131462.8 | 38291 | -0.550 | -0.2626 | Yes | ||
| 166 | CENPL | ENSG00000120334.15 | 38315 | -0.553 | -0.2548 | Yes | ||
| 167 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2465 | Yes | ||
| 168 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2449 | Yes | ||
| 169 | CEP290 | ENSG00000198707.16 | 38626 | -0.564 | -0.2370 | Yes | ||
| 170 | CDCA8 | ENSG00000134690.11 | 38629 | -0.564 | -0.2286 | Yes | ||
| 171 | PPP2CB | ENSG00000104695.13 | 38708 | -0.572 | -0.2219 | Yes | ||
| 172 | CENPM | ENSG00000100162.15 | 38711 | -0.572 | -0.2133 | Yes | ||
| 173 | SKA2 | ENSG00000182628.13 | 38739 | -0.574 | -0.2054 | Yes | ||
| 174 | NCAPH | ENSG00000121152.10 | 38902 | -0.590 | -0.2004 | Yes | ||
| 175 | CDCA5 | ENSG00000146670.10 | 38957 | -0.596 | -0.1928 | Yes | ||
| 176 | SGO2 | ENSG00000163535.18 | 38980 | -0.599 | -0.1843 | Yes | ||
| 177 | SMC2 | ENSG00000136824.19 | 39061 | -0.608 | -0.1771 | Yes | ||
| 178 | TUBB | ENSG00000196230.13 | 39081 | -0.611 | -0.1684 | Yes | ||
| 179 | NCAPG | ENSG00000109805.10 | 39169 | -0.616 | -0.1612 | Yes | ||
| 180 | ZWINT | ENSG00000122952.17 | 39173 | -0.616 | -0.1520 | Yes | ||
| 181 | PLK4 | ENSG00000142731.11 | 39267 | -0.620 | -0.1450 | Yes | ||
| 182 | CLIP1 | ENSG00000130779.20 | 39284 | -0.622 | -0.1360 | Yes | ||
| 183 | CENPF | ENSG00000117724.13 | 39444 | -0.631 | -0.1304 | Yes | ||
| 184 | CDK1 | ENSG00000170312.16 | 39453 | -0.632 | -0.1211 | Yes | ||
| 185 | MZT1 | ENSG00000204899.6 | 39731 | -0.665 | -0.1179 | Yes | ||
| 186 | KNTC1 | ENSG00000184445.12 | 39875 | -0.690 | -0.1110 | Yes | ||
| 187 | ERCC6L | ENSG00000186871.7 | 39947 | -0.704 | -0.1021 | Yes | ||
| 188 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.0949 | Yes | ||
| 189 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.0840 | Yes | ||
| 190 | ZWILCH | ENSG00000174442.12 | 40134 | -0.739 | -0.0734 | Yes | ||
| 191 | KNL1 | ENSG00000137812.19 | 40136 | -0.739 | -0.0623 | Yes | ||
| 192 | CENPE | ENSG00000138778.12 | 40145 | -0.740 | -0.0514 | Yes | ||
| 193 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.0427 | Yes | ||
| 194 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0360 | Yes | ||
| 195 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | -0.0287 | Yes | ||
| 196 | KIF18A | ENSG00000121621.7 | 40921 | -1.038 | -0.0156 | Yes | ||
| 197 | CENPI | ENSG00000102384.13 | 41099 | -1.425 | 0.0015 | Yes |
