Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_RHO_GTPASES_ACTIVATE_FORMINS |
| Enrichment Score (ES) | -0.5946323 |
| Normalized Enrichment Score (NES) | -3.0411131 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | EVL | ENSG00000196405.13 | 5263 | 0.474 | -0.1190 | No | ||
| 2 | DYNC1I1 | ENSG00000158560.14 | 7076 | 0.386 | -0.1556 | No | ||
| 3 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1742 | No | ||
| 4 | RCC2 | ENSG00000179051.14 | 9112 | 0.331 | -0.1917 | No | ||
| 5 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.2243 | No | ||
| 6 | CENPP | ENSG00000188312.14 | 10894 | 0.295 | -0.2234 | No | ||
| 7 | DVL2 | ENSG00000004975.12 | 13260 | 0.230 | -0.2765 | No | ||
| 8 | ITGB3BP | ENSG00000142856.16 | 13741 | 0.215 | -0.2840 | No | ||
| 9 | RHOD | ENSG00000173156.7 | 13948 | 0.208 | -0.2850 | No | ||
| 10 | B9D2 | ENSG00000123810.8 | 14121 | 0.202 | -0.2852 | No | ||
| 11 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.3184 | No | ||
| 12 | RPS27 | ENSG00000177954.14 | 15622 | 0.156 | -0.3156 | No | ||
| 13 | RANGAP1 | ENSG00000100401.19 | 15733 | 0.152 | -0.3153 | No | ||
| 14 | CENPC | ENSG00000145241.11 | 15881 | 0.148 | -0.3160 | No | ||
| 15 | RHOB | ENSG00000143878.10 | 16535 | 0.130 | -0.3294 | No | ||
| 16 | PPP2R5A | ENSG00000066027.12 | 16937 | 0.118 | -0.3368 | No | ||
| 17 | FMNL1 | ENSG00000184922.14 | 17281 | 0.110 | -0.3430 | No | ||
| 18 | PMF1 | ENSG00000160783.19 | 17911 | 0.093 | -0.3565 | No | ||
| 19 | NUP160 | ENSG00000030066.13 | 18845 | 0.069 | -0.3779 | No | ||
| 20 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3876 | No | ||
| 21 | DVL1 | ENSG00000107404.20 | 19947 | 0.040 | -0.4028 | No | ||
| 22 | NUP43 | ENSG00000120253.14 | 20047 | 0.038 | -0.4045 | No | ||
| 23 | CENPT | ENSG00000102901.13 | 20096 | 0.037 | -0.4050 | No | ||
| 24 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.4338 | No | ||
| 25 | SEC13 | ENSG00000157020.18 | 22468 | -0.026 | -0.4621 | No | ||
| 26 | NDEL1 | ENSG00000166579.15 | 22882 | -0.036 | -0.4715 | No | ||
| 27 | DAAM1 | ENSG00000100592.15 | 22886 | -0.036 | -0.4709 | No | ||
| 28 | DYNLL2 | ENSG00000264364.3 | 23336 | -0.048 | -0.4809 | No | ||
| 29 | NUDC | ENSG00000090273.14 | 23568 | -0.054 | -0.4854 | No | ||
| 30 | SEH1L | ENSG00000085415.16 | 23768 | -0.059 | -0.4891 | No | ||
| 31 | NDE1 | ENSG00000072864.15 | 23985 | -0.064 | -0.4931 | No | ||
| 32 | NUP133 | ENSG00000069248.12 | 24802 | -0.086 | -0.5114 | No | ||
| 33 | DVL3 | ENSG00000161202.20 | 24922 | -0.089 | -0.5125 | No | ||
| 34 | PPP2R5D | ENSG00000112640.15 | 24932 | -0.090 | -0.5110 | No | ||
| 35 | MIS12 | ENSG00000167842.15 | 25231 | -0.097 | -0.5163 | No | ||
| 36 | NSL1 | ENSG00000117697.15 | 25239 | -0.097 | -0.5146 | No | ||
| 37 | DYNC1LI2 | ENSG00000135720.13 | 25352 | -0.101 | -0.5154 | No | ||
| 38 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.5415 | No | ||
| 39 | NUP107 | ENSG00000111581.10 | 26867 | -0.145 | -0.5467 | No | ||
| 40 | PPP2R5E | ENSG00000154001.14 | 27182 | -0.155 | -0.5513 | No | ||
| 41 | NUP85 | ENSG00000125450.11 | 27774 | -0.173 | -0.5624 | No | ||
| 42 | SCAI | ENSG00000173611.17 | 27825 | -0.175 | -0.5602 | No | ||
| 43 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.5568 | No | ||
| 44 | CLASP1 | ENSG00000074054.18 | 28043 | -0.182 | -0.5584 | No | ||
| 45 | FMNL3 | ENSG00000161791.14 | 28065 | -0.183 | -0.5554 | No | ||
| 46 | NUP98 | ENSG00000110713.17 | 28185 | -0.186 | -0.5546 | No | ||
| 47 | CLASP2 | ENSG00000163539.17 | 28270 | -0.189 | -0.5530 | No | ||
| 48 | PPP1CC | ENSG00000186298.12 | 28475 | -0.195 | -0.5541 | No | ||
| 49 | SRC | ENSG00000197122.11 | 28621 | -0.200 | -0.5537 | No | ||
| 50 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.5666 | No | ||
| 51 | DIAPH1 | ENSG00000131504.17 | 29982 | -0.243 | -0.5777 | No | ||
| 52 | PPP2R5C | ENSG00000078304.19 | 30677 | -0.265 | -0.5894 | Yes | ||
| 53 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.5852 | Yes | ||
| 54 | ZW10 | ENSG00000086827.9 | 30856 | -0.271 | -0.5832 | Yes | ||
| 55 | PPP2R1B | ENSG00000137713.16 | 30954 | -0.276 | -0.5802 | Yes | ||
| 56 | PPP2R5B | ENSG00000068971.14 | 31101 | -0.281 | -0.5782 | Yes | ||
| 57 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.5728 | Yes | ||
| 58 | RHOC | ENSG00000155366.16 | 31789 | -0.289 | -0.5838 | Yes | ||
| 59 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.5788 | Yes | ||
| 60 | BUB3 | ENSG00000154473.18 | 32087 | -0.300 | -0.5794 | Yes | ||
| 61 | INCENP | ENSG00000149503.13 | 32126 | -0.301 | -0.5744 | Yes | ||
| 62 | CENPQ | ENSG00000031691.7 | 32142 | -0.302 | -0.5689 | Yes | ||
| 63 | MRTFA | ENSG00000196588.17 | 32346 | -0.311 | -0.5677 | Yes | ||
| 64 | CENPO | ENSG00000138092.11 | 32352 | -0.312 | -0.5617 | Yes | ||
| 65 | CENPU | ENSG00000151725.12 | 32395 | -0.313 | -0.5566 | Yes | ||
| 66 | PPP2CA | ENSG00000113575.10 | 32408 | -0.314 | -0.5507 | Yes | ||
| 67 | NUF2 | ENSG00000143228.13 | 32503 | -0.317 | -0.5468 | Yes | ||
| 68 | RANBP2 | ENSG00000153201.16 | 32550 | -0.318 | -0.5417 | Yes | ||
| 69 | AHCTF1 | ENSG00000153207.15 | 32851 | -0.330 | -0.5426 | Yes | ||
| 70 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.5441 | Yes | ||
| 71 | DSN1 | ENSG00000149636.15 | 34130 | -0.346 | -0.5603 | Yes | ||
| 72 | CDC20 | ENSG00000117399.14 | 34187 | -0.349 | -0.5548 | Yes | ||
| 73 | PFN2 | ENSG00000070087.14 | 34203 | -0.350 | -0.5483 | Yes | ||
| 74 | PPP2R1A | ENSG00000105568.18 | 34725 | -0.357 | -0.5540 | Yes | ||
| 75 | TAOK1 | ENSG00000160551.11 | 34732 | -0.358 | -0.5472 | Yes | ||
| 76 | SGO1 | ENSG00000129810.15 | 34782 | -0.360 | -0.5413 | Yes | ||
| 77 | FMNL2 | ENSG00000157827.20 | 35058 | -0.368 | -0.5408 | Yes | ||
| 78 | CENPH | ENSG00000153044.10 | 35190 | -0.373 | -0.5367 | Yes | ||
| 79 | CENPS | ENSG00000175279.22 | 35550 | -0.391 | -0.5377 | Yes | ||
| 80 | NUP37 | ENSG00000075188.9 | 35611 | -0.394 | -0.5315 | Yes | ||
| 81 | SRGAP2 | ENSG00000266028.7 | 35672 | -0.396 | -0.5252 | Yes | ||
| 82 | PAFAH1B1 | ENSG00000007168.13 | 36076 | -0.408 | -0.5270 | Yes | ||
| 83 | CENPK | ENSG00000123219.13 | 36086 | -0.408 | -0.5192 | Yes | ||
| 84 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.5128 | Yes | ||
| 85 | BIRC5 | ENSG00000089685.15 | 36279 | -0.415 | -0.5077 | Yes | ||
| 86 | ACTG1 | ENSG00000184009.12 | 36290 | -0.416 | -0.4998 | Yes | ||
| 87 | RHOA | ENSG00000067560.12 | 36363 | -0.419 | -0.4933 | Yes | ||
| 88 | SPC24 | ENSG00000161888.11 | 36669 | -0.434 | -0.4922 | Yes | ||
| 89 | PLK1 | ENSG00000166851.15 | 36707 | -0.436 | -0.4846 | Yes | ||
| 90 | KIF2C | ENSG00000142945.13 | 36852 | -0.443 | -0.4794 | Yes | ||
| 91 | CENPN | ENSG00000166451.13 | 36906 | -0.447 | -0.4719 | Yes | ||
| 92 | SRF | ENSG00000112658.8 | 36941 | -0.449 | -0.4640 | Yes | ||
| 93 | KIF2A | ENSG00000068796.16 | 36994 | -0.452 | -0.4564 | Yes | ||
| 94 | SPC25 | ENSG00000152253.9 | 37054 | -0.455 | -0.4489 | Yes | ||
| 95 | MAPRE1 | ENSG00000101367.9 | 37101 | -0.458 | -0.4410 | Yes | ||
| 96 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.4350 | Yes | ||
| 97 | DIAPH2 | ENSG00000147202.18 | 37240 | -0.467 | -0.4261 | Yes | ||
| 98 | MAD1L1 | ENSG00000002822.15 | 37265 | -0.468 | -0.4175 | Yes | ||
| 99 | RAC1 | ENSG00000136238.18 | 37298 | -0.471 | -0.4090 | Yes | ||
| 100 | SPDL1 | ENSG00000040275.17 | 37361 | -0.475 | -0.4012 | Yes | ||
| 101 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3930 | Yes | ||
| 102 | AURKB | ENSG00000178999.13 | 37485 | -0.484 | -0.3853 | Yes | ||
| 103 | SKA1 | ENSG00000154839.10 | 37525 | -0.487 | -0.3767 | Yes | ||
| 104 | ITGB1 | ENSG00000150093.19 | 37687 | -0.501 | -0.3708 | Yes | ||
| 105 | BUB1 | ENSG00000169679.15 | 37763 | -0.508 | -0.3627 | Yes | ||
| 106 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.3538 | Yes | ||
| 107 | MAD2L1 | ENSG00000164109.14 | 37893 | -0.520 | -0.3456 | Yes | ||
| 108 | NDC80 | ENSG00000080986.13 | 37927 | -0.522 | -0.3361 | Yes | ||
| 109 | CENPA | ENSG00000115163.15 | 37993 | -0.527 | -0.3274 | Yes | ||
| 110 | BUB1B | ENSG00000156970.12 | 38129 | -0.537 | -0.3201 | Yes | ||
| 111 | CDC42 | ENSG00000070831.17 | 38194 | -0.542 | -0.3111 | Yes | ||
| 112 | DYNC1LI1 | ENSG00000144635.9 | 38271 | -0.548 | -0.3022 | Yes | ||
| 113 | CENPL | ENSG00000120334.15 | 38315 | -0.553 | -0.2924 | Yes | ||
| 114 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2815 | Yes | ||
| 115 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2774 | Yes | ||
| 116 | PFN1 | ENSG00000108518.7 | 38610 | -0.563 | -0.2666 | Yes | ||
| 117 | CDCA8 | ENSG00000134690.11 | 38629 | -0.564 | -0.2560 | Yes | ||
| 118 | PPP2CB | ENSG00000104695.13 | 38708 | -0.572 | -0.2467 | Yes | ||
| 119 | CENPM | ENSG00000100162.15 | 38711 | -0.572 | -0.2355 | Yes | ||
| 120 | SKA2 | ENSG00000182628.13 | 38739 | -0.574 | -0.2249 | Yes | ||
| 121 | SGO2 | ENSG00000163535.18 | 38980 | -0.599 | -0.2190 | Yes | ||
| 122 | ZWINT | ENSG00000122952.17 | 39173 | -0.616 | -0.2116 | Yes | ||
| 123 | CLIP1 | ENSG00000130779.20 | 39284 | -0.622 | -0.2021 | Yes | ||
| 124 | CENPF | ENSG00000117724.13 | 39444 | -0.631 | -0.1936 | Yes | ||
| 125 | KNTC1 | ENSG00000184445.12 | 39875 | -0.690 | -0.1905 | Yes | ||
| 126 | ERCC6L | ENSG00000186871.7 | 39947 | -0.704 | -0.1785 | Yes | ||
| 127 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.1680 | Yes | ||
| 128 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.1536 | Yes | ||
| 129 | ZWILCH | ENSG00000174442.12 | 40134 | -0.739 | -0.1397 | Yes | ||
| 130 | KNL1 | ENSG00000137812.19 | 40136 | -0.739 | -0.1252 | Yes | ||
| 131 | CENPE | ENSG00000138778.12 | 40145 | -0.740 | -0.1109 | Yes | ||
| 132 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.0988 | Yes | ||
| 133 | ACTB | ENSG00000075624.16 | 40426 | -0.816 | -0.0867 | Yes | ||
| 134 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0722 | Yes | ||
| 135 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | -0.0604 | Yes | ||
| 136 | KIF18A | ENSG00000121621.7 | 40921 | -1.038 | -0.0426 | Yes | ||
| 137 | DIAPH3 | ENSG00000139734.19 | 40924 | -1.041 | -0.0222 | Yes | ||
| 138 | CENPI | ENSG00000102384.13 | 41099 | -1.425 | 0.0015 | Yes |
