Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS |
| Enrichment Score (ES) | -0.6050543 |
| Normalized Enrichment Score (NES) | -2.2502654 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.994575E-4 |
| FWER p-Value | 0.009 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IQGAP2 | ENSG00000145703.16 | 6469 | 0.409 | -0.1271 | No | ||
| 2 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1411 | No | ||
| 3 | MEN1 | ENSG00000133895.15 | 8178 | 0.354 | -0.1163 | No | ||
| 4 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.1551 | No | ||
| 5 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.2630 | No | ||
| 6 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3483 | No | ||
| 7 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.3965 | No | ||
| 8 | CTNNB1 | ENSG00000168036.18 | 24288 | -0.073 | -0.4642 | No | ||
| 9 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.5087 | No | ||
| 10 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.5273 | No | ||
| 11 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.5474 | No | ||
| 12 | CTNNA1 | ENSG00000044115.21 | 30649 | -0.264 | -0.5600 | No | ||
| 13 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.5420 | No | ||
| 14 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.5307 | No | ||
| 15 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.5565 | No | ||
| 16 | IQGAP3 | ENSG00000183856.11 | 35185 | -0.373 | -0.5776 | Yes | ||
| 17 | ACTG1 | ENSG00000184009.12 | 36290 | -0.416 | -0.5738 | Yes | ||
| 18 | RAC1 | ENSG00000136238.18 | 37298 | -0.471 | -0.5636 | Yes | ||
| 19 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.5311 | Yes | ||
| 20 | CDC42 | ENSG00000070831.17 | 38194 | -0.542 | -0.5101 | Yes | ||
| 21 | CALM1 | ENSG00000198668.12 | 38464 | -0.558 | -0.4755 | Yes | ||
| 22 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.4374 | Yes | ||
| 23 | IQGAP1 | ENSG00000140575.13 | 38621 | -0.564 | -0.3964 | Yes | ||
| 24 | CLIP1 | ENSG00000130779.20 | 39284 | -0.622 | -0.3667 | Yes | ||
| 25 | CDH1 | ENSG00000039068.19 | 40053 | -0.722 | -0.3322 | Yes | ||
| 26 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.2794 | Yes | ||
| 27 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.2255 | Yes | ||
| 28 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.1727 | Yes | ||
| 29 | ACTB | ENSG00000075624.16 | 40426 | -0.816 | -0.1164 | Yes | ||
| 30 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0564 | Yes | ||
| 31 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | 0.0084 | Yes |
