Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_RHO_GTPASES_ACTIVATE_PAKS |
| Enrichment Score (ES) | -0.6853601 |
| Normalized Enrichment Score (NES) | -2.3123598 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.8163807E-4 |
| FWER p-Value | 0.003 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PAK3 | ENSG00000077264.15 | 1408 | 0.788 | 0.0427 | No | ||
| 2 | MYH10 | ENSG00000133026.12 | 12352 | 0.259 | -0.1980 | No | ||
| 3 | MYH14 | ENSG00000105357.17 | 26877 | -0.146 | -0.5369 | No | ||
| 4 | LIMK1 | ENSG00000106683.15 | 27117 | -0.153 | -0.5278 | No | ||
| 5 | PPP1R12B | ENSG00000077157.22 | 27498 | -0.164 | -0.5210 | No | ||
| 6 | CTTN | ENSG00000085733.16 | 28654 | -0.201 | -0.5294 | No | ||
| 7 | MYLK | ENSG00000065534.18 | 35071 | -0.368 | -0.6495 | Yes | ||
| 8 | PPP1CB | ENSG00000213639.10 | 36325 | -0.417 | -0.6392 | Yes | ||
| 9 | PAK1 | ENSG00000149269.9 | 36549 | -0.430 | -0.6027 | Yes | ||
| 10 | PAK2 | ENSG00000180370.10 | 36983 | -0.451 | -0.5691 | Yes | ||
| 11 | RAC1 | ENSG00000136238.18 | 37298 | -0.471 | -0.5308 | Yes | ||
| 12 | MYH11 | ENSG00000133392.18 | 37382 | -0.477 | -0.4862 | Yes | ||
| 13 | FLNA | ENSG00000196924.17 | 37839 | -0.515 | -0.4470 | Yes | ||
| 14 | NF2 | ENSG00000186575.18 | 37996 | -0.527 | -0.3993 | Yes | ||
| 15 | CDC42 | ENSG00000070831.17 | 38194 | -0.542 | -0.3512 | Yes | ||
| 16 | CALM1 | ENSG00000198668.12 | 38464 | -0.558 | -0.3032 | Yes | ||
| 17 | MYH9 | ENSG00000100345.21 | 39531 | -0.641 | -0.2666 | Yes | ||
| 18 | MYL6 | ENSG00000092841.18 | 40195 | -0.751 | -0.2094 | Yes | ||
| 19 | MYL12B | ENSG00000118680.13 | 40197 | -0.752 | -0.1360 | Yes | ||
| 20 | PPP1R12A | ENSG00000058272.19 | 40248 | -0.765 | -0.0626 | Yes | ||
| 21 | MYL9 | ENSG00000101335.10 | 40576 | -0.868 | 0.0142 | Yes |
