Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_SWITCHING_OF_ORIGINS_TO_A_POST_REPLICATIVE_STATE |
| Enrichment Score (ES) | -0.5133826 |
| Normalized Enrichment Score (NES) | -2.4121082 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.545775E-5 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ANAPC2 | ENSG00000176248.9 | 6153 | 0.426 | -0.1310 | No | ||
| 2 | ANAPC5 | ENSG00000089053.13 | 6368 | 0.414 | -0.1179 | No | ||
| 3 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2961 | No | ||
| 4 | CDC26 | ENSG00000176386.9 | 15890 | 0.148 | -0.3341 | No | ||
| 5 | MCM7 | ENSG00000166508.17 | 17495 | 0.104 | -0.3686 | No | ||
| 6 | CCNA1 | ENSG00000133101.10 | 17734 | 0.098 | -0.3700 | No | ||
| 7 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.4050 | No | ||
| 8 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.4057 | No | ||
| 9 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.4074 | No | ||
| 10 | ORC2 | ENSG00000115942.9 | 19607 | 0.048 | -0.4063 | No | ||
| 11 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.4126 | No | ||
| 12 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.4330 | No | ||
| 13 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.4358 | No | ||
| 14 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.4359 | No | ||
| 15 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.4392 | No | ||
| 16 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.4632 | No | ||
| 17 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.4650 | No | ||
| 18 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4815 | No | ||
| 19 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4810 | No | ||
| 20 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4856 | No | ||
| 21 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4837 | No | ||
| 22 | ORC5 | ENSG00000164815.11 | 23413 | -0.050 | -0.4830 | No | ||
| 23 | ANAPC1 | ENSG00000153107.13 | 24092 | -0.067 | -0.4966 | No | ||
| 24 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4968 | No | ||
| 25 | CUL1 | ENSG00000055130.17 | 24550 | -0.079 | -0.5011 | No | ||
| 26 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.5023 | No | ||
| 27 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.4996 | No | ||
| 28 | FZR1 | ENSG00000105325.14 | 24842 | -0.087 | -0.4968 | No | ||
| 29 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.5085 | Yes | ||
| 30 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.5085 | Yes | ||
| 31 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.5058 | Yes | ||
| 32 | ANAPC10 | ENSG00000164162.14 | 26104 | -0.124 | -0.5073 | Yes | ||
| 33 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.5045 | Yes | ||
| 34 | ANAPC7 | ENSG00000196510.12 | 26263 | -0.128 | -0.4999 | Yes | ||
| 35 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.4953 | Yes | ||
| 36 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.4899 | Yes | ||
| 37 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.4871 | Yes | ||
| 38 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.4815 | Yes | ||
| 39 | ANAPC11 | ENSG00000141552.17 | 26543 | -0.136 | -0.4773 | Yes | ||
| 40 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.4742 | Yes | ||
| 41 | ANAPC4 | ENSG00000053900.10 | 26737 | -0.142 | -0.4695 | Yes | ||
| 42 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.4650 | Yes | ||
| 43 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.4772 | Yes | ||
| 44 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.4719 | Yes | ||
| 45 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.4654 | Yes | ||
| 46 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4622 | Yes | ||
| 47 | ORC4 | ENSG00000115947.13 | 28129 | -0.185 | -0.4582 | Yes | ||
| 48 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.4568 | Yes | ||
| 49 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.4488 | Yes | ||
| 50 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.4442 | Yes | ||
| 51 | SKP1 | ENSG00000113558.18 | 28827 | -0.206 | -0.4400 | Yes | ||
| 52 | ANAPC16 | ENSG00000166295.9 | 29001 | -0.212 | -0.4348 | Yes | ||
| 53 | MCM3 | ENSG00000112118.20 | 29007 | -0.212 | -0.4256 | Yes | ||
| 54 | CDC27 | ENSG00000004897.12 | 29738 | -0.236 | -0.4329 | Yes | ||
| 55 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.4285 | Yes | ||
| 56 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.4201 | Yes | ||
| 57 | CDC23 | ENSG00000094880.11 | 30249 | -0.252 | -0.4124 | Yes | ||
| 58 | UBE2D1 | ENSG00000072401.15 | 30679 | -0.265 | -0.4112 | Yes | ||
| 59 | MCM8 | ENSG00000125885.13 | 31052 | -0.279 | -0.4079 | Yes | ||
| 60 | PSMA8 | ENSG00000154611.14 | 31324 | -0.285 | -0.4019 | Yes | ||
| 61 | CCNE1 | ENSG00000105173.14 | 32197 | -0.305 | -0.4096 | Yes | ||
| 62 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.3972 | Yes | ||
| 63 | RBX1 | ENSG00000100387.9 | 32483 | -0.316 | -0.3890 | Yes | ||
| 64 | MCM2 | ENSG00000073111.14 | 32546 | -0.318 | -0.3764 | Yes | ||
| 65 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.3657 | Yes | ||
| 66 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.3528 | Yes | ||
| 67 | MCM6 | ENSG00000076003.5 | 34728 | -0.357 | -0.3850 | Yes | ||
| 68 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.3763 | Yes | ||
| 69 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.3658 | Yes | ||
| 70 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.3520 | Yes | ||
| 71 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.3396 | Yes | ||
| 72 | CDT1 | ENSG00000167513.9 | 35789 | -0.401 | -0.3255 | Yes | ||
| 73 | CDC16 | ENSG00000130177.16 | 35800 | -0.402 | -0.3080 | Yes | ||
| 74 | MCM5 | ENSG00000100297.16 | 35805 | -0.402 | -0.2903 | Yes | ||
| 75 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.2759 | Yes | ||
| 76 | ORC3 | ENSG00000135336.14 | 36389 | -0.421 | -0.2681 | Yes | ||
| 77 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.2501 | Yes | ||
| 78 | ANAPC15 | ENSG00000110200.8 | 36886 | -0.445 | -0.2418 | Yes | ||
| 79 | ORC1 | ENSG00000085840.13 | 37179 | -0.462 | -0.2284 | Yes | ||
| 80 | CCNE2 | ENSG00000175305.17 | 37360 | -0.475 | -0.2118 | Yes | ||
| 81 | UBE2E1 | ENSG00000170142.12 | 37384 | -0.477 | -0.1913 | Yes | ||
| 82 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.1773 | Yes | ||
| 83 | PSME4 | ENSG00000068878.15 | 38072 | -0.532 | -0.1622 | Yes | ||
| 84 | UBE2C | ENSG00000175063.17 | 38091 | -0.534 | -0.1390 | Yes | ||
| 85 | ORC6 | ENSG00000091651.9 | 38888 | -0.589 | -0.1323 | Yes | ||
| 86 | CDC6 | ENSG00000094804.12 | 40060 | -0.723 | -0.1288 | Yes | ||
| 87 | SKP2 | ENSG00000145604.16 | 40211 | -0.755 | -0.0991 | Yes | ||
| 88 | MCM4 | ENSG00000104738.18 | 40591 | -0.872 | -0.0698 | Yes | ||
| 89 | CCNA2 | ENSG00000145386.10 | 40598 | -0.874 | -0.0313 | Yes | ||
| 90 | PSMB11 | ENSG00000222028.5 | 40874 | -1.018 | 0.0070 | Yes |
