Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_S_PHASE |
| Enrichment Score (ES) | -0.50864464 |
| Normalized Enrichment Score (NES) | -2.6547523 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | E2F5 | ENSG00000133740.11 | 2048 | 0.699 | -0.0346 | No | ||
| 2 | CDKN1B | ENSG00000111276.11 | 4380 | 0.521 | -0.0800 | No | ||
| 3 | ANAPC2 | ENSG00000176248.9 | 6153 | 0.426 | -0.1139 | No | ||
| 4 | ANAPC5 | ENSG00000089053.13 | 6368 | 0.414 | -0.1100 | No | ||
| 5 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2931 | No | ||
| 6 | POLE4 | ENSG00000115350.12 | 15368 | 0.163 | -0.3215 | No | ||
| 7 | TFDP2 | ENSG00000114126.17 | 15564 | 0.157 | -0.3228 | No | ||
| 8 | CDC25B | ENSG00000101224.17 | 15629 | 0.156 | -0.3209 | No | ||
| 9 | CDC26 | ENSG00000176386.9 | 15890 | 0.148 | -0.3240 | No | ||
| 10 | PTK6 | ENSG00000101213.7 | 16081 | 0.143 | -0.3255 | No | ||
| 11 | PDS5B | ENSG00000083642.19 | 16191 | 0.140 | -0.3251 | No | ||
| 12 | RFC5 | ENSG00000111445.14 | 16883 | 0.120 | -0.3393 | No | ||
| 13 | RPA2 | ENSG00000117748.10 | 16945 | 0.118 | -0.3382 | No | ||
| 14 | MCM7 | ENSG00000166508.17 | 17495 | 0.104 | -0.3493 | No | ||
| 15 | CCNA1 | ENSG00000133101.10 | 17734 | 0.098 | -0.3530 | No | ||
| 16 | AKT2 | ENSG00000105221.18 | 18110 | 0.088 | -0.3602 | No | ||
| 17 | RBBP4 | ENSG00000162521.19 | 18441 | 0.081 | -0.3665 | No | ||
| 18 | RAD21 | ENSG00000164754.14 | 18730 | 0.073 | -0.3719 | No | ||
| 19 | E2F4 | ENSG00000205250.9 | 19102 | 0.062 | -0.3796 | No | ||
| 20 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.3825 | No | ||
| 21 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.3844 | No | ||
| 22 | POLE | ENSG00000177084.17 | 19403 | 0.054 | -0.3832 | No | ||
| 23 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.3860 | No | ||
| 24 | ORC2 | ENSG00000115942.9 | 19607 | 0.048 | -0.3860 | No | ||
| 25 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.3932 | No | ||
| 26 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.4140 | No | ||
| 27 | RBL2 | ENSG00000103479.16 | 20946 | 0.014 | -0.4170 | No | ||
| 28 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.4168 | No | ||
| 29 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.4171 | No | ||
| 30 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.4206 | No | ||
| 31 | CDKN1A | ENSG00000124762.13 | 21297 | 0.004 | -0.4247 | No | ||
| 32 | AKT1 | ENSG00000142208.16 | 21695 | -0.006 | -0.4342 | No | ||
| 33 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.4448 | No | ||
| 34 | POLD4 | ENSG00000175482.9 | 22165 | -0.017 | -0.4449 | No | ||
| 35 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.4467 | No | ||
| 36 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4640 | No | ||
| 37 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4645 | No | ||
| 38 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4701 | No | ||
| 39 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4693 | No | ||
| 40 | ORC5 | ENSG00000164815.11 | 23413 | -0.050 | -0.4698 | No | ||
| 41 | POLE3 | ENSG00000148229.13 | 23456 | -0.051 | -0.4697 | No | ||
| 42 | LIN37 | ENSG00000267796.8 | 23851 | -0.062 | -0.4779 | No | ||
| 43 | ANAPC1 | ENSG00000153107.13 | 24092 | -0.067 | -0.4823 | No | ||
| 44 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4841 | No | ||
| 45 | CUL1 | ENSG00000055130.17 | 24550 | -0.079 | -0.4902 | No | ||
| 46 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.4933 | No | ||
| 47 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.4925 | No | ||
| 48 | FZR1 | ENSG00000105325.14 | 24842 | -0.087 | -0.4916 | No | ||
| 49 | POLA2 | ENSG00000014138.9 | 24862 | -0.087 | -0.4901 | No | ||
| 50 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.5038 | No | ||
| 51 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.5062 | Yes | ||
| 52 | DNA2 | ENSG00000138346.15 | 25812 | -0.114 | -0.5060 | Yes | ||
| 53 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.5035 | Yes | ||
| 54 | POLD1 | ENSG00000062822.14 | 25827 | -0.115 | -0.5013 | Yes | ||
| 55 | ANAPC10 | ENSG00000164162.14 | 26104 | -0.124 | -0.5053 | Yes | ||
| 56 | RFC1 | ENSG00000035928.16 | 26169 | -0.125 | -0.5041 | Yes | ||
| 57 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.5025 | Yes | ||
| 58 | POLD3 | ENSG00000077514.9 | 26261 | -0.128 | -0.5007 | Yes | ||
| 59 | ANAPC7 | ENSG00000196510.12 | 26263 | -0.128 | -0.4979 | Yes | ||
| 60 | CDK4 | ENSG00000135446.17 | 26296 | -0.129 | -0.4959 | Yes | ||
| 61 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.4934 | Yes | ||
| 62 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.4908 | Yes | ||
| 63 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.4911 | Yes | ||
| 64 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.4884 | Yes | ||
| 65 | POLA1 | ENSG00000101868.11 | 26537 | -0.136 | -0.4871 | Yes | ||
| 66 | ANAPC11 | ENSG00000141552.17 | 26543 | -0.136 | -0.4843 | Yes | ||
| 67 | RFC2 | ENSG00000049541.11 | 26606 | -0.138 | -0.4827 | Yes | ||
| 68 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.4812 | Yes | ||
| 69 | ANAPC4 | ENSG00000053900.10 | 26737 | -0.142 | -0.4797 | Yes | ||
| 70 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.4784 | Yes | ||
| 71 | MAX | ENSG00000125952.20 | 27563 | -0.167 | -0.4930 | Yes | ||
| 72 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.4907 | Yes | ||
| 73 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.4892 | Yes | ||
| 74 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.4865 | Yes | ||
| 75 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4873 | Yes | ||
| 76 | ORC4 | ENSG00000115947.13 | 28129 | -0.185 | -0.4875 | Yes | ||
| 77 | STAG1 | ENSG00000118007.13 | 28245 | -0.188 | -0.4861 | Yes | ||
| 78 | LIG1 | ENSG00000105486.14 | 28401 | -0.193 | -0.4857 | Yes | ||
| 79 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.4820 | Yes | ||
| 80 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.4783 | Yes | ||
| 81 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.4782 | Yes | ||
| 82 | CCNH | ENSG00000134480.15 | 28769 | -0.204 | -0.4772 | Yes | ||
| 83 | SKP1 | ENSG00000113558.18 | 28827 | -0.206 | -0.4741 | Yes | ||
| 84 | ANAPC16 | ENSG00000166295.9 | 29001 | -0.212 | -0.4736 | Yes | ||
| 85 | MCM3 | ENSG00000112118.20 | 29007 | -0.212 | -0.4691 | Yes | ||
| 86 | CDC27 | ENSG00000004897.12 | 29738 | -0.236 | -0.4817 | Yes | ||
| 87 | POLD2 | ENSG00000106628.10 | 29968 | -0.243 | -0.4820 | Yes | ||
| 88 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.4774 | Yes | ||
| 89 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.4745 | Yes | ||
| 90 | CDC23 | ENSG00000094880.11 | 30249 | -0.252 | -0.4725 | Yes | ||
| 91 | CKS1B | ENSG00000173207.13 | 30473 | -0.259 | -0.4722 | Yes | ||
| 92 | RFC4 | ENSG00000163918.10 | 30672 | -0.265 | -0.4712 | Yes | ||
| 93 | UBE2D1 | ENSG00000072401.15 | 30679 | -0.265 | -0.4656 | Yes | ||
| 94 | LIN54 | ENSG00000189308.11 | 30719 | -0.267 | -0.4607 | Yes | ||
| 95 | MCM8 | ENSG00000125885.13 | 31052 | -0.279 | -0.4626 | Yes | ||
| 96 | RPA1 | ENSG00000132383.12 | 31119 | -0.282 | -0.4581 | Yes | ||
| 97 | CABLES1 | ENSG00000134508.12 | 31130 | -0.282 | -0.4521 | Yes | ||
| 98 | PSMA8 | ENSG00000154611.14 | 31324 | -0.285 | -0.4506 | Yes | ||
| 99 | PDS5A | ENSG00000121892.15 | 31964 | -0.295 | -0.4597 | Yes | ||
| 100 | CCNE1 | ENSG00000105173.14 | 32197 | -0.305 | -0.4587 | Yes | ||
| 101 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.4531 | Yes | ||
| 102 | RBX1 | ENSG00000100387.9 | 32483 | -0.316 | -0.4519 | Yes | ||
| 103 | MCM2 | ENSG00000073111.14 | 32546 | -0.318 | -0.4464 | Yes | ||
| 104 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.4429 | Yes | ||
| 105 | ESCO1 | ENSG00000141446.11 | 32723 | -0.325 | -0.4365 | Yes | ||
| 106 | LIN52 | ENSG00000205659.10 | 32727 | -0.325 | -0.4294 | Yes | ||
| 107 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.4229 | Yes | ||
| 108 | RB1 | ENSG00000139687.15 | 33569 | -0.339 | -0.4353 | Yes | ||
| 109 | MCM6 | ENSG00000076003.5 | 34728 | -0.357 | -0.4557 | Yes | ||
| 110 | STAG2 | ENSG00000101972.18 | 34834 | -0.363 | -0.4503 | Yes | ||
| 111 | AKT3 | ENSG00000117020.18 | 35028 | -0.366 | -0.4470 | Yes | ||
| 112 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.4392 | Yes | ||
| 113 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.4371 | Yes | ||
| 114 | MNAT1 | ENSG00000020426.11 | 35332 | -0.380 | -0.4296 | Yes | ||
| 115 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.4236 | Yes | ||
| 116 | TFDP1 | ENSG00000198176.13 | 35512 | -0.389 | -0.4170 | Yes | ||
| 117 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.4114 | Yes | ||
| 118 | CDT1 | ENSG00000167513.9 | 35789 | -0.401 | -0.4062 | Yes | ||
| 119 | CDC16 | ENSG00000130177.16 | 35800 | -0.402 | -0.3976 | Yes | ||
| 120 | MCM5 | ENSG00000100297.16 | 35805 | -0.402 | -0.3889 | Yes | ||
| 121 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.3835 | Yes | ||
| 122 | ORC3 | ENSG00000135336.14 | 36389 | -0.421 | -0.3850 | Yes | ||
| 123 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.3765 | Yes | ||
| 124 | WAPL | ENSG00000062650.19 | 36609 | -0.432 | -0.3716 | Yes | ||
| 125 | RPA3 | ENSG00000106399.11 | 36661 | -0.434 | -0.3634 | Yes | ||
| 126 | GINS3 | ENSG00000181938.13 | 36693 | -0.435 | -0.3546 | Yes | ||
| 127 | ANAPC15 | ENSG00000110200.8 | 36886 | -0.445 | -0.3495 | Yes | ||
| 128 | SMC3 | ENSG00000108055.9 | 36921 | -0.447 | -0.3405 | Yes | ||
| 129 | PCNA | ENSG00000132646.11 | 37166 | -0.461 | -0.3363 | Yes | ||
| 130 | ORC1 | ENSG00000085840.13 | 37179 | -0.462 | -0.3265 | Yes | ||
| 131 | LIN9 | ENSG00000183814.15 | 37237 | -0.466 | -0.3176 | Yes | ||
| 132 | CCNE2 | ENSG00000175305.17 | 37360 | -0.475 | -0.3102 | Yes | ||
| 133 | UBE2E1 | ENSG00000170142.12 | 37384 | -0.477 | -0.3003 | Yes | ||
| 134 | RFC3 | ENSG00000133119.13 | 37532 | -0.487 | -0.2932 | Yes | ||
| 135 | GSK3B | ENSG00000082701.15 | 37577 | -0.491 | -0.2834 | Yes | ||
| 136 | POLE2 | ENSG00000100479.13 | 37582 | -0.492 | -0.2728 | Yes | ||
| 137 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.2651 | Yes | ||
| 138 | SMC1A | ENSG00000072501.17 | 37922 | -0.522 | -0.2585 | Yes | ||
| 139 | CDK7 | ENSG00000134058.12 | 37950 | -0.524 | -0.2476 | Yes | ||
| 140 | GINS2 | ENSG00000131153.9 | 37954 | -0.524 | -0.2362 | Yes | ||
| 141 | PSME4 | ENSG00000068878.15 | 38072 | -0.532 | -0.2274 | Yes | ||
| 142 | E2F1 | ENSG00000101412.13 | 38085 | -0.533 | -0.2160 | Yes | ||
| 143 | UBE2C | ENSG00000175063.17 | 38091 | -0.534 | -0.2044 | Yes | ||
| 144 | CCND1 | ENSG00000110092.3 | 38307 | -0.552 | -0.1975 | Yes | ||
| 145 | PRIM1 | ENSG00000198056.15 | 38325 | -0.554 | -0.1857 | Yes | ||
| 146 | FEN1 | ENSG00000168496.4 | 38636 | -0.565 | -0.1809 | Yes | ||
| 147 | CDC45 | ENSG00000093009.10 | 38822 | -0.583 | -0.1726 | Yes | ||
| 148 | ORC6 | ENSG00000091651.9 | 38888 | -0.589 | -0.1613 | Yes | ||
| 149 | CDCA5 | ENSG00000146670.10 | 38957 | -0.596 | -0.1499 | Yes | ||
| 150 | MYC | ENSG00000136997.19 | 39003 | -0.602 | -0.1378 | Yes | ||
| 151 | GINS4 | ENSG00000147536.12 | 39830 | -0.681 | -0.1430 | Yes | ||
| 152 | PRIM2 | ENSG00000146143.19 | 39937 | -0.702 | -0.1301 | Yes | ||
| 153 | WEE1 | ENSG00000166483.11 | 40002 | -0.714 | -0.1160 | Yes | ||
| 154 | CDC6 | ENSG00000094804.12 | 40060 | -0.723 | -0.1016 | Yes | ||
| 155 | GINS1 | ENSG00000101003.10 | 40151 | -0.741 | -0.0875 | Yes | ||
| 156 | SKP2 | ENSG00000145604.16 | 40211 | -0.755 | -0.0724 | Yes | ||
| 157 | CDC25A | ENSG00000164045.12 | 40263 | -0.768 | -0.0568 | Yes | ||
| 158 | ESCO2 | ENSG00000171320.15 | 40430 | -0.817 | -0.0429 | Yes | ||
| 159 | MCM4 | ENSG00000104738.18 | 40591 | -0.872 | -0.0276 | Yes | ||
| 160 | CCNA2 | ENSG00000145386.10 | 40598 | -0.874 | -0.0086 | Yes | ||
| 161 | PSMB11 | ENSG00000222028.5 | 40874 | -1.018 | 0.0070 | Yes |
