Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | KEGG_HEMATOPOIETIC_CELL_LINEAGE |
| Enrichment Score (ES) | 0.43502098 |
| Normalized Enrichment Score (NES) | 1.7076117 |
| Nominal p-value | 0.0029850747 |
| FDR q-value | 0.06899954 |
| FWER p-Value | 0.96 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IL6R | ENSG00000160712.13 | 12 | 4.560 | 0.0463 | Yes | ||
| 2 | KITLG | ENSG00000049130.16 | 67 | 3.954 | 0.0855 | Yes | ||
| 3 | CD44 | ENSG00000026508.18 | 157 | 3.446 | 0.1187 | Yes | ||
| 4 | IL11RA | ENSG00000137070.17 | 169 | 3.385 | 0.1530 | Yes | ||
| 5 | IL7 | ENSG00000104432.14 | 187 | 3.332 | 0.1867 | Yes | ||
| 6 | ANPEP | ENSG00000166825.14 | 265 | 3.089 | 0.2164 | Yes | ||
| 7 | KIT | ENSG00000157404.15 | 270 | 3.076 | 0.2478 | Yes | ||
| 8 | ITGA2 | ENSG00000164171.11 | 327 | 2.899 | 0.2761 | Yes | ||
| 9 | FLT3LG | ENSG00000090554.13 | 428 | 2.716 | 0.3016 | Yes | ||
| 10 | IL1R1 | ENSG00000115594.12 | 542 | 2.559 | 0.3251 | Yes | ||
| 11 | MME | ENSG00000196549.10 | 753 | 2.306 | 0.3438 | Yes | ||
| 12 | CD22 | ENSG00000012124.17 | 1097 | 2.051 | 0.3568 | Yes | ||
| 13 | CD9 | ENSG00000010278.14 | 1562 | 1.814 | 0.3646 | Yes | ||
| 14 | CD14 | ENSG00000170458.14 | 1584 | 1.809 | 0.3826 | Yes | ||
| 15 | CD59 | ENSG00000085063.16 | 1662 | 1.770 | 0.3989 | Yes | ||
| 16 | CD36 | ENSG00000135218.19 | 2200 | 1.566 | 0.4024 | Yes | ||
| 17 | CSF1 | ENSG00000184371.14 | 2219 | 1.559 | 0.4179 | Yes | ||
| 18 | TFRC | ENSG00000072274.13 | 2501 | 1.475 | 0.4265 | Yes | ||
| 19 | IL1R2 | ENSG00000115590.14 | 2747 | 1.394 | 0.4350 | Yes | ||
| 20 | IL5 | ENSG00000113525.10 | 4807 | 0.996 | 0.3974 | No | ||
| 21 | CR1 | ENSG00000203710.11 | 5061 | 0.959 | 0.4013 | No | ||
| 22 | GP1BA | ENSG00000185245.8 | 5108 | 0.953 | 0.4100 | No | ||
| 23 | CD55 | ENSG00000196352.15 | 5115 | 0.952 | 0.4196 | No | ||
| 24 | ITGA4 | ENSG00000115232.14 | 5278 | 0.930 | 0.4253 | No | ||
| 25 | IL4 | ENSG00000113520.11 | 7818 | 0.662 | 0.3731 | No | ||
| 26 | CD3G | ENSG00000160654.10 | 7987 | 0.648 | 0.3758 | No | ||
| 27 | CD38 | ENSG00000004468.13 | 8415 | 0.611 | 0.3721 | No | ||
| 28 | ITGA2B | ENSG00000005961.19 | 8876 | 0.577 | 0.3673 | No | ||
| 29 | CSF3R | ENSG00000119535.17 | 9393 | 0.544 | 0.3609 | No | ||
| 30 | MS4A1 | ENSG00000156738.17 | 9759 | 0.522 | 0.3578 | No | ||
| 31 | IL2RA | ENSG00000134460.17 | 9914 | 0.516 | 0.3595 | No | ||
| 32 | IL1A | ENSG00000115008.5 | 10008 | 0.511 | 0.3625 | No | ||
| 33 | EPOR | ENSG00000187266.14 | 10084 | 0.505 | 0.3659 | No | ||
| 34 | HLA-DRB1 | ENSG00000196126.11 | 11131 | 0.437 | 0.3461 | No | ||
| 35 | ITGA1 | ENSG00000213949.10 | 11169 | 0.434 | 0.3497 | No | ||
| 36 | CD33 | ENSG00000105383.15 | 12186 | 0.377 | 0.3299 | No | ||
| 37 | CD19 | ENSG00000177455.14 | 12407 | 0.369 | 0.3286 | No | ||
| 38 | HLA-DRA | ENSG00000204287.14 | 14089 | 0.312 | 0.2927 | No | ||
| 39 | FCGR1A | ENSG00000150337.13 | 14587 | 0.305 | 0.2843 | No | ||
| 40 | GP5 | ENSG00000178732.5 | 16136 | 0.241 | 0.2508 | No | ||
| 41 | CD8B | ENSG00000172116.23 | 16808 | 0.206 | 0.2373 | No | ||
| 42 | IL1B | ENSG00000125538.12 | 17487 | 0.172 | 0.2233 | No | ||
| 43 | HLA-DRB5 | ENSG00000198502.6 | 18132 | 0.139 | 0.2098 | No | ||
| 44 | GYPA | ENSG00000170180.22 | 19896 | 0.052 | 0.1693 | No | ||
| 45 | CD7 | ENSG00000173762.8 | 20028 | 0.047 | 0.1668 | No | ||
| 46 | CD8A | ENSG00000153563.15 | 21477 | -0.031 | 0.1334 | No | ||
| 47 | CD4 | ENSG00000010610.10 | 22265 | -0.072 | 0.1159 | No | ||
| 48 | IL7R | ENSG00000168685.15 | 23218 | -0.125 | 0.0951 | No | ||
| 49 | FLT3 | ENSG00000122025.14 | 23558 | -0.144 | 0.0887 | No | ||
| 50 | DNTT | ENSG00000107447.8 | 23612 | -0.147 | 0.0889 | No | ||
| 51 | EPO | ENSG00000130427.3 | 24705 | -0.212 | 0.0657 | No | ||
| 52 | CD1B | ENSG00000158485.11 | 25122 | -0.223 | 0.0583 | No | ||
| 53 | CD2 | ENSG00000116824.5 | 25496 | -0.227 | 0.0520 | No | ||
| 54 | CD3E | ENSG00000198851.9 | 29128 | -0.355 | -0.0287 | No | ||
| 55 | ITGB3 | ENSG00000259207.7 | 31330 | -0.481 | -0.0750 | No | ||
| 56 | CR2 | ENSG00000117322.17 | 31514 | -0.489 | -0.0742 | No | ||
| 57 | CD1A | ENSG00000158477.7 | 32488 | -0.542 | -0.0913 | No | ||
| 58 | CD5 | ENSG00000110448.11 | 32651 | -0.556 | -0.0893 | No | ||
| 59 | CD3D | ENSG00000167286.9 | 32821 | -0.570 | -0.0874 | No | ||
| 60 | IL5RA | ENSG00000091181.19 | 34528 | -0.704 | -0.1199 | No | ||
| 61 | IL4R | ENSG00000077238.14 | 35619 | -0.801 | -0.1370 | No | ||
| 62 | GP9 | ENSG00000169704.4 | 36202 | -0.868 | -0.1417 | No | ||
| 63 | TPO | ENSG00000115705.21 | 36496 | -0.900 | -0.1393 | No | ||
| 64 | IL6 | ENSG00000136244.12 | 37366 | -1.015 | -0.1491 | No | ||
| 65 | IL3 | ENSG00000164399.5 | 37554 | -1.043 | -0.1428 | No | ||
| 66 | TNF | ENSG00000232810.4 | 37586 | -1.048 | -0.1328 | No | ||
| 67 | THPO | ENSG00000090534.20 | 38027 | -1.122 | -0.1315 | No | ||
| 68 | CD34 | ENSG00000174059.17 | 38113 | -1.137 | -0.1219 | No | ||
| 69 | CD37 | ENSG00000104894.12 | 38942 | -1.297 | -0.1279 | No | ||
| 70 | CSF2 | ENSG00000164400.6 | 40320 | -1.633 | -0.1432 | No | ||
| 71 | ITGA5 | ENSG00000161638.11 | 40419 | -1.662 | -0.1285 | No | ||
| 72 | CD1D | ENSG00000158473.6 | 40635 | -1.730 | -0.1158 | No | ||
| 73 | ITGAM | ENSG00000169896.18 | 40880 | -1.815 | -0.1029 | No | ||
| 74 | IL11 | ENSG00000095752.7 | 41469 | -2.115 | -0.0949 | No | ||
| 75 | CSF1R | ENSG00000182578.13 | 42031 | -2.511 | -0.0823 | No | ||
| 76 | CSF3 | ENSG00000108342.12 | 42130 | -2.616 | -0.0578 | No | ||
| 77 | ITGA3 | ENSG00000005884.18 | 42556 | -3.222 | -0.0348 | No | ||
| 78 | ITGA6 | ENSG00000091409.15 | 42992 | -4.680 | 0.0030 | No |
