Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM |
| Enrichment Score (ES) | -0.6732315 |
| Normalized Enrichment Score (NES) | -2.3768315 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CACNA2D4 | ENSG00000151062.15 | 124 | 3.591 | 0.0188 | No | ||
| 2 | CACNA1C | ENSG00000151067.22 | 193 | 3.311 | 0.0373 | No | ||
| 3 | ITGA2 | ENSG00000164171.11 | 327 | 2.899 | 0.0517 | No | ||
| 4 | CACNB3 | ENSG00000167535.8 | 947 | 2.135 | 0.0502 | No | ||
| 5 | ACE | ENSG00000159640.16 | 1197 | 1.991 | 0.0565 | No | ||
| 6 | CACNA1D | ENSG00000157388.19 | 2414 | 1.501 | 0.0373 | No | ||
| 7 | ITGB8 | ENSG00000105855.10 | 3741 | 1.176 | 0.0136 | No | ||
| 8 | CACNA2D2 | ENSG00000007402.11 | 3855 | 1.154 | 0.0179 | No | ||
| 9 | ITGB5 | ENSG00000082781.12 | 4315 | 1.074 | 0.0138 | No | ||
| 10 | CACNA2D3 | ENSG00000157445.15 | 4802 | 0.997 | 0.0085 | No | ||
| 11 | CACNG7 | ENSG00000105605.7 | 5004 | 0.967 | 0.0097 | No | ||
| 12 | CACNB2 | ENSG00000165995.20 | 5260 | 0.933 | 0.0094 | No | ||
| 13 | ITGA4 | ENSG00000115232.14 | 5278 | 0.930 | 0.0146 | No | ||
| 14 | PRKAG1 | ENSG00000181929.13 | 6839 | 0.753 | -0.0171 | No | ||
| 15 | CACNG2 | ENSG00000166862.6 | 6896 | 0.747 | -0.0139 | No | ||
| 16 | CACNA1F | ENSG00000102001.12 | 7370 | 0.703 | -0.0206 | No | ||
| 17 | CACNB4 | ENSG00000182389.19 | 8084 | 0.640 | -0.0333 | No | ||
| 18 | ITGA2B | ENSG00000005961.19 | 8876 | 0.577 | -0.0482 | No | ||
| 19 | ITGA8 | ENSG00000077943.8 | 9725 | 0.522 | -0.0647 | No | ||
| 20 | TPM4 | ENSG00000167460.17 | 11125 | 0.437 | -0.0946 | No | ||
| 21 | ITGA1 | ENSG00000213949.10 | 11169 | 0.434 | -0.0930 | No | ||
| 22 | PRKAA1 | ENSG00000132356.11 | 11381 | 0.422 | -0.0953 | No | ||
| 23 | LMNA | ENSG00000160789.20 | 15491 | 0.275 | -0.1891 | No | ||
| 24 | PRKAB1 | ENSG00000111725.11 | 16157 | 0.239 | -0.2031 | No | ||
| 25 | ITGB4 | ENSG00000132470.14 | 16947 | 0.199 | -0.2203 | No | ||
| 26 | EMD | ENSG00000102119.10 | 18485 | 0.125 | -0.2552 | No | ||
| 27 | ITGA11 | ENSG00000137809.17 | 18873 | 0.105 | -0.2636 | No | ||
| 28 | CACNG8 | ENSG00000142408.4 | 21638 | -0.039 | -0.3276 | No | ||
| 29 | LAMA2 | ENSG00000196569.12 | 22603 | -0.091 | -0.3494 | No | ||
| 30 | CACNG3 | ENSG00000006116.3 | 26144 | -0.263 | -0.4301 | No | ||
| 31 | RYR2 | ENSG00000198626.17 | 28784 | -0.351 | -0.4893 | No | ||
| 32 | IGF1 | ENSG00000017427.16 | 30420 | -0.433 | -0.5247 | No | ||
| 33 | ACTG1 | ENSG00000184009.12 | 30626 | -0.445 | -0.5267 | No | ||
| 34 | ITGB3 | ENSG00000259207.7 | 31330 | -0.481 | -0.5402 | No | ||
| 35 | ITGA9 | ENSG00000144668.12 | 33291 | -0.604 | -0.5820 | No | ||
| 36 | DAG1 | ENSG00000173402.11 | 34450 | -0.698 | -0.6047 | No | ||
| 37 | TGFB3 | ENSG00000119699.7 | 35467 | -0.784 | -0.6236 | No | ||
| 38 | ITGB7 | ENSG00000139626.16 | 36016 | -0.846 | -0.6312 | No | ||
| 39 | ITGB1 | ENSG00000150093.19 | 36454 | -0.895 | -0.6360 | No | ||
| 40 | IL6 | ENSG00000136244.12 | 37366 | -1.015 | -0.6510 | No | ||
| 41 | TNF | ENSG00000232810.4 | 37586 | -1.048 | -0.6498 | No | ||
| 42 | SGCB | ENSG00000163069.12 | 38176 | -1.149 | -0.6565 | No | ||
| 43 | TGFB1 | ENSG00000105329.10 | 38478 | -1.201 | -0.6562 | No | ||
| 44 | ACTB | ENSG00000075624.16 | 38506 | -1.208 | -0.6496 | No | ||
| 45 | ITGA10 | ENSG00000143127.13 | 39526 | -1.426 | -0.6646 | Yes | ||
| 46 | MYL3 | ENSG00000160808.10 | 39809 | -1.495 | -0.6621 | Yes | ||
| 47 | CACNG4 | ENSG00000075461.6 | 40209 | -1.603 | -0.6617 | Yes | ||
| 48 | ITGA5 | ENSG00000161638.11 | 40419 | -1.662 | -0.6565 | Yes | ||
| 49 | SGCD | ENSG00000170624.13 | 41042 | -1.886 | -0.6596 | Yes | ||
| 50 | ITGAV | ENSG00000138448.12 | 41100 | -1.907 | -0.6494 | Yes | ||
| 51 | TNNI3 | ENSG00000129991.13 | 41255 | -1.980 | -0.6410 | Yes | ||
| 52 | TPM3 | ENSG00000143549.21 | 41507 | -2.135 | -0.6339 | Yes | ||
| 53 | TGFB2 | ENSG00000092969.12 | 41517 | -2.139 | -0.6212 | Yes | ||
| 54 | PRKAG2 | ENSG00000106617.14 | 41635 | -2.213 | -0.6105 | Yes | ||
| 55 | CACNG6 | ENSG00000130433.7 | 41917 | -2.421 | -0.6024 | Yes | ||
| 56 | SLC8A1 | ENSG00000183023.18 | 41918 | -2.421 | -0.5878 | Yes | ||
| 57 | PRKAA2 | ENSG00000162409.11 | 41921 | -2.424 | -0.5732 | Yes | ||
| 58 | CACNA2D1 | ENSG00000153956.16 | 41945 | -2.451 | -0.5589 | Yes | ||
| 59 | ATP2A2 | ENSG00000174437.17 | 42170 | -2.663 | -0.5480 | Yes | ||
| 60 | SGCG | ENSG00000102683.7 | 42272 | -2.813 | -0.5334 | Yes | ||
| 61 | PRKAB2 | ENSG00000131791.8 | 42379 | -2.953 | -0.5180 | Yes | ||
| 62 | ITGA3 | ENSG00000005884.18 | 42556 | -3.222 | -0.5026 | Yes | ||
| 63 | SGCA | ENSG00000108823.16 | 42629 | -3.407 | -0.4837 | Yes | ||
| 64 | MYH7 | ENSG00000092054.13 | 42632 | -3.422 | -0.4630 | Yes | ||
| 65 | TTN | ENSG00000155657.26 | 42690 | -3.572 | -0.4428 | Yes | ||
| 66 | TPM1 | ENSG00000140416.21 | 42794 | -3.877 | -0.4217 | Yes | ||
| 67 | CACNB1 | ENSG00000067191.16 | 42803 | -3.923 | -0.3982 | Yes | ||
| 68 | TPM2 | ENSG00000198467.15 | 42854 | -4.136 | -0.3744 | Yes | ||
| 69 | ITGA7 | ENSG00000135424.16 | 42920 | -4.354 | -0.3496 | Yes | ||
| 70 | DMD | ENSG00000198947.15 | 42943 | -4.488 | -0.3229 | Yes | ||
| 71 | ITGA6 | ENSG00000091409.15 | 42992 | -4.680 | -0.2958 | Yes | ||
| 72 | MYL2 | ENSG00000111245.15 | 43025 | -4.822 | -0.2674 | Yes | ||
| 73 | PRKAG3 | ENSG00000115592.11 | 43035 | -4.840 | -0.2383 | Yes | ||
| 74 | CACNG1 | ENSG00000108878.5 | 43077 | -4.944 | -0.2094 | Yes | ||
| 75 | DES | ENSG00000175084.12 | 43086 | -4.954 | -0.1796 | Yes | ||
| 76 | TNNT2 | ENSG00000118194.20 | 43098 | -4.967 | -0.1499 | Yes | ||
| 77 | MYH6 | ENSG00000197616.12 | 43099 | -4.967 | -0.1198 | Yes | ||
| 78 | TNNC1 | ENSG00000114854.8 | 43100 | -4.968 | -0.0898 | Yes | ||
| 79 | CACNA1S | ENSG00000081248.11 | 43107 | -4.973 | -0.0599 | Yes | ||
| 80 | ACTC1 | ENSG00000159251.8 | 43108 | -4.973 | -0.0298 | Yes | ||
| 81 | ITGB6 | ENSG00000115221.12 | 43111 | -4.974 | 0.0002 | Yes |
