Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | KEGG_PARKINSONS_DISEASE |
| Enrichment Score (ES) | -0.5299767 |
| Normalized Enrichment Score (NES) | -2.0206509 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0010643674 |
| FWER p-Value | 0.033 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LRRK2 | ENSG00000188906.16 | 49 | 4.121 | 0.0338 | No | ||
| 2 | SNCAIP | ENSG00000064692.19 | 387 | 2.772 | 0.0495 | No | ||
| 3 | UBE2L6 | ENSG00000156587.16 | 391 | 2.767 | 0.0730 | No | ||
| 4 | UBA7 | ENSG00000182179.13 | 500 | 2.599 | 0.0925 | No | ||
| 5 | SNCA | ENSG00000145335.15 | 3307 | 1.267 | 0.0380 | No | ||
| 6 | SDHD | ENSG00000204370.12 | 3584 | 1.209 | 0.0418 | No | ||
| 7 | NDUFA7 | ENSG00000267855.6 | 7349 | 0.706 | -0.0397 | No | ||
| 8 | UQCRB | ENSG00000156467.9 | 10109 | 0.503 | -0.0996 | No | ||
| 9 | NDUFA4L2 | ENSG00000185633.10 | 15433 | 0.279 | -0.2211 | No | ||
| 10 | SLC18A2 | ENSG00000165646.14 | 15584 | 0.271 | -0.2222 | No | ||
| 11 | NDUFS4 | ENSG00000164258.12 | 15726 | 0.264 | -0.2233 | No | ||
| 12 | COX4I1 | ENSG00000131143.9 | 15881 | 0.255 | -0.2247 | No | ||
| 13 | COX6CP3 | ENSG00000266251.1 | 17155 | 0.190 | -0.2527 | No | ||
| 14 | UBB | ENSG00000170315.14 | 17176 | 0.189 | -0.2516 | No | ||
| 15 | ATP5F1E | ENSG00000124172.10 | 19090 | 0.095 | -0.2952 | No | ||
| 16 | NDUFB10 | ENSG00000140990.15 | 19165 | 0.090 | -0.2962 | No | ||
| 17 | ATP5F1D | ENSG00000099624.8 | 19774 | 0.057 | -0.3098 | No | ||
| 18 | UCHL1 | ENSG00000154277.13 | 20978 | -0.003 | -0.3378 | No | ||
| 19 | UQCRH | ENSG00000173660.12 | 21041 | -0.006 | -0.3392 | No | ||
| 20 | NDUFA2 | ENSG00000131495.8 | 21146 | -0.013 | -0.3415 | No | ||
| 21 | COX7A2L | ENSG00000115944.15 | 21364 | -0.024 | -0.3463 | No | ||
| 22 | UQCR11 | ENSG00000127540.12 | 21789 | -0.046 | -0.3558 | No | ||
| 23 | NDUFB1 | ENSG00000183648.10 | 22559 | -0.088 | -0.3729 | No | ||
| 24 | COX7C | ENSG00000127184.13 | 23199 | -0.124 | -0.3868 | No | ||
| 25 | HTRA2 | ENSG00000115317.11 | 23340 | -0.132 | -0.3889 | No | ||
| 26 | UBE2L3 | ENSG00000185651.14 | 23515 | -0.141 | -0.3917 | No | ||
| 27 | NDUFS7 | ENSG00000115286.20 | 23943 | -0.168 | -0.4002 | No | ||
| 28 | NDUFB8 | ENSG00000166136.16 | 23962 | -0.169 | -0.3992 | No | ||
| 29 | SDHA | ENSG00000073578.17 | 24192 | -0.182 | -0.4030 | No | ||
| 30 | NDUFC2 | ENSG00000151366.13 | 24279 | -0.187 | -0.4034 | No | ||
| 31 | COX7A1 | ENSG00000161281.11 | 25467 | -0.225 | -0.4291 | No | ||
| 32 | COX6B1 | ENSG00000126267.11 | 25561 | -0.231 | -0.4293 | No | ||
| 33 | NDUFC1 | ENSG00000109390.12 | 26484 | -0.265 | -0.4485 | No | ||
| 34 | COX8C | ENSG00000187581.3 | 26545 | -0.269 | -0.4476 | No | ||
| 35 | NDUFA5 | ENSG00000128609.15 | 27038 | -0.276 | -0.4567 | No | ||
| 36 | ATP5PD | ENSG00000167863.12 | 28443 | -0.334 | -0.4865 | No | ||
| 37 | UQCRHL | ENSG00000233954.6 | 28555 | -0.340 | -0.4862 | No | ||
| 38 | COX4I2 | ENSG00000131055.5 | 29371 | -0.368 | -0.5021 | No | ||
| 39 | COX6A1 | ENSG00000111775.3 | 29637 | -0.384 | -0.5050 | No | ||
| 40 | PRKN | ENSG00000185345.21 | 30023 | -0.409 | -0.5105 | No | ||
| 41 | NDUFS3 | ENSG00000213619.10 | 30108 | -0.414 | -0.5089 | No | ||
| 42 | NDUFS8 | ENSG00000110717.13 | 30259 | -0.426 | -0.5088 | No | ||
| 43 | UBE2J1 | ENSG00000198833.7 | 30261 | -0.426 | -0.5052 | No | ||
| 44 | NDUFA6 | ENSG00000184983.11 | 30283 | -0.428 | -0.5021 | No | ||
| 45 | SDHC | ENSG00000143252.14 | 30372 | -0.429 | -0.5005 | No | ||
| 46 | NDUFA10 | ENSG00000130414.12 | 30583 | -0.440 | -0.5016 | No | ||
| 47 | UBE2J2 | ENSG00000160087.20 | 30850 | -0.457 | -0.5039 | No | ||
| 48 | NDUFB7 | ENSG00000099795.7 | 30995 | -0.459 | -0.5034 | No | ||
| 49 | ATP5PO | ENSG00000241837.7 | 31091 | -0.467 | -0.5016 | No | ||
| 50 | NDUFV1 | ENSG00000167792.13 | 31274 | -0.476 | -0.5018 | No | ||
| 51 | NDUFB4 | ENSG00000065518.8 | 31830 | -0.503 | -0.5104 | No | ||
| 52 | NDUFA1 | ENSG00000125356.7 | 32133 | -0.521 | -0.5130 | No | ||
| 53 | NDUFB5 | ENSG00000136521.13 | 32252 | -0.531 | -0.5113 | No | ||
| 54 | ATP5F1A | ENSG00000152234.16 | 33057 | -0.587 | -0.5250 | Yes | ||
| 55 | SDHB | ENSG00000117118.9 | 33081 | -0.589 | -0.5205 | Yes | ||
| 56 | ATP5MC1P5 | ENSG00000227590.2 | 33130 | -0.593 | -0.5166 | Yes | ||
| 57 | MT-ND6 | ENSG00000198695.2 | 33237 | -0.601 | -0.5140 | Yes | ||
| 58 | TH | ENSG00000180176.14 | 33344 | -0.609 | -0.5113 | Yes | ||
| 59 | SLC6A3 | ENSG00000142319.18 | 33448 | -0.617 | -0.5084 | Yes | ||
| 60 | MT-ND1 | ENSG00000198888.2 | 33602 | -0.630 | -0.5067 | Yes | ||
| 61 | NDUFV2 | ENSG00000178127.13 | 33641 | -0.633 | -0.5022 | Yes | ||
| 62 | MT-ND5 | ENSG00000198786.2 | 33909 | -0.654 | -0.5028 | Yes | ||
| 63 | NDUFB2 | ENSG00000090266.13 | 33932 | -0.656 | -0.4978 | Yes | ||
| 64 | COX5B | ENSG00000135940.7 | 33952 | -0.658 | -0.4926 | Yes | ||
| 65 | MT-ATP6 | ENSG00000198899.2 | 34264 | -0.680 | -0.4941 | Yes | ||
| 66 | COX8A | ENSG00000176340.4 | 34436 | -0.697 | -0.4921 | Yes | ||
| 67 | MT-CO3 | ENSG00000198938.2 | 34569 | -0.708 | -0.4892 | Yes | ||
| 68 | MT-CO1 | ENSG00000198804.2 | 34603 | -0.710 | -0.4839 | Yes | ||
| 69 | NDUFA3 | ENSG00000170906.16 | 35193 | -0.759 | -0.4912 | Yes | ||
| 70 | MT-ATP8 | ENSG00000228253.1 | 35268 | -0.765 | -0.4864 | Yes | ||
| 71 | ATP5MC3 | ENSG00000154518.9 | 35448 | -0.783 | -0.4840 | Yes | ||
| 72 | MT-ND3 | ENSG00000198840.2 | 35569 | -0.794 | -0.4800 | Yes | ||
| 73 | GPR37 | ENSG00000170775.3 | 35711 | -0.810 | -0.4764 | Yes | ||
| 74 | ATP5MC2 | ENSG00000135390.20 | 35892 | -0.830 | -0.4736 | Yes | ||
| 75 | MT-ND4L | ENSG00000212907.2 | 36434 | -0.893 | -0.4786 | Yes | ||
| 76 | MT-ND4 | ENSG00000198886.2 | 36465 | -0.896 | -0.4716 | Yes | ||
| 77 | ATP5PB | ENSG00000116459.11 | 36670 | -0.924 | -0.4685 | Yes | ||
| 78 | UQCRFS1 | ENSG00000169021.6 | 37078 | -0.978 | -0.4697 | Yes | ||
| 79 | NDUFV3 | ENSG00000160194.18 | 37212 | -0.994 | -0.4644 | Yes | ||
| 80 | UBA1 | ENSG00000130985.17 | 37220 | -0.995 | -0.4561 | Yes | ||
| 81 | UBE2G2 | ENSG00000184787.19 | 37488 | -1.032 | -0.4535 | Yes | ||
| 82 | PARK7 | ENSG00000116288.13 | 37537 | -1.039 | -0.4458 | Yes | ||
| 83 | NDUFS6 | ENSG00000145494.11 | 37676 | -1.062 | -0.4400 | Yes | ||
| 84 | MT-ND2 | ENSG00000198763.3 | 37747 | -1.076 | -0.4325 | Yes | ||
| 85 | SLC25A5 | ENSG00000005022.6 | 37760 | -1.078 | -0.4236 | Yes | ||
| 86 | MT-CYB | ENSG00000198727.2 | 37765 | -1.078 | -0.4146 | Yes | ||
| 87 | UQCR10 | ENSG00000184076.13 | 37826 | -1.087 | -0.4068 | Yes | ||
| 88 | ATP5PF | ENSG00000154723.12 | 37895 | -1.100 | -0.3990 | Yes | ||
| 89 | COX7B | ENSG00000131174.7 | 37903 | -1.101 | -0.3898 | Yes | ||
| 90 | NDUFA9 | ENSG00000139180.11 | 38015 | -1.119 | -0.3829 | Yes | ||
| 91 | PPID | ENSG00000171497.5 | 38103 | -1.135 | -0.3753 | Yes | ||
| 92 | UQCRQ | ENSG00000164405.11 | 38111 | -1.136 | -0.3658 | Yes | ||
| 93 | NDUFS5 | ENSG00000168653.11 | 38239 | -1.160 | -0.3589 | Yes | ||
| 94 | UBE2G1 | ENSG00000132388.12 | 38303 | -1.173 | -0.3504 | Yes | ||
| 95 | NDUFB6 | ENSG00000165264.11 | 38305 | -1.173 | -0.3405 | Yes | ||
| 96 | NDUFA8 | ENSG00000119421.7 | 38322 | -1.176 | -0.3309 | Yes | ||
| 97 | ATP5F1C | ENSG00000165629.20 | 38343 | -1.178 | -0.3213 | Yes | ||
| 98 | APAF1 | ENSG00000120868.13 | 38448 | -1.197 | -0.3136 | Yes | ||
| 99 | CYC1 | ENSG00000179091.5 | 38710 | -1.245 | -0.3091 | Yes | ||
| 100 | UQCRC1 | ENSG00000010256.11 | 38824 | -1.273 | -0.3009 | Yes | ||
| 101 | MT-CO2 | ENSG00000198712.1 | 38915 | -1.292 | -0.2920 | Yes | ||
| 102 | PINK1 | ENSG00000158828.8 | 39057 | -1.322 | -0.2841 | Yes | ||
| 103 | CASP9 | ENSG00000132906.18 | 39565 | -1.434 | -0.2837 | Yes | ||
| 104 | COX6C | ENSG00000164919.11 | 39588 | -1.439 | -0.2720 | Yes | ||
| 105 | NDUFA4 | ENSG00000189043.10 | 39683 | -1.463 | -0.2618 | Yes | ||
| 106 | COX6B2 | ENSG00000160471.13 | 39727 | -1.474 | -0.2503 | Yes | ||
| 107 | VDAC1 | ENSG00000213585.11 | 39742 | -1.476 | -0.2381 | Yes | ||
| 108 | VDAC3 | ENSG00000078668.14 | 39954 | -1.536 | -0.2299 | Yes | ||
| 109 | NDUFB3 | ENSG00000119013.9 | 40121 | -1.579 | -0.2204 | Yes | ||
| 110 | VDAC2 | ENSG00000165637.13 | 40139 | -1.584 | -0.2074 | Yes | ||
| 111 | ATP5MC1 | ENSG00000159199.14 | 40212 | -1.603 | -0.1954 | Yes | ||
| 112 | ATP5F1B | ENSG00000110955.9 | 40290 | -1.624 | -0.1834 | Yes | ||
| 113 | COX7A2 | ENSG00000112695.11 | 40291 | -1.624 | -0.1696 | Yes | ||
| 114 | NDUFS1 | ENSG00000023228.14 | 40350 | -1.642 | -0.1571 | Yes | ||
| 115 | COX5A | ENSG00000178741.12 | 40756 | -1.769 | -0.1515 | Yes | ||
| 116 | UQCRC2 | ENSG00000140740.11 | 40862 | -1.806 | -0.1386 | Yes | ||
| 117 | SLC25A31 | ENSG00000151475.6 | 41060 | -1.892 | -0.1271 | Yes | ||
| 118 | NDUFB9 | ENSG00000147684.9 | 41155 | -1.935 | -0.1129 | Yes | ||
| 119 | NDUFS2 | ENSG00000158864.12 | 41582 | -2.182 | -0.1042 | Yes | ||
| 120 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.0877 | Yes | ||
| 121 | CASP3 | ENSG00000164305.19 | 42313 | -2.869 | -0.0778 | Yes | ||
| 122 | CYCS | ENSG00000172115.8 | 42546 | -3.206 | -0.0560 | Yes | ||
| 123 | SLC25A4 | ENSG00000151729.11 | 42557 | -3.224 | -0.0289 | Yes | ||
| 124 | COX6A2 | ENSG00000156885.6 | 43073 | -4.938 | 0.0011 | Yes |
