Details for gene set NABA_CORE_MATRISOME[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	NABA_CORE_MATRISOME
Enrichment Score (ES)	0.4326739
Normalized Enrichment Score (NES)	2.0344965
Nominal p-value	0.0
FDR q-value	0.0048085405
FWER p-Value	0.05

Fig 1: Enrichment plot: NABA_CORE_MATRISOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLIT3	ENSG00000184347.14			0	4.923	0.0140	Yes
2	MFAP4	ENSG00000166482.11			2	4.870	0.0279	Yes
3	DCN	ENSG00000011465.17			6	4.734	0.0413	Yes
4	FBLN5	ENSG00000140092.14			11	4.579	0.0542	Yes
5	BMPER	ENSG00000164619.10			17	4.433	0.0667	Yes
6	PCOLCE	ENSG00000106333.13			33	4.267	0.0785	Yes
7	FBLN1	ENSG00000077942.19			63	3.993	0.0892	Yes
8	COL26A1	ENSG00000160963.14			88	3.782	0.0994	Yes
9	VWCE	ENSG00000167992.13			118	3.609	0.1090	Yes
10	CTHRC1	ENSG00000164932.13			123	3.593	0.1192	Yes
11	PODN	ENSG00000174348.13			125	3.589	0.1294	Yes
12	LAMA4	ENSG00000112769.20			127	3.582	0.1395	Yes
13	IGFBP4	ENSG00000141753.7			151	3.478	0.1489	Yes
14	PRELP	ENSG00000188783.6			188	3.330	0.1575	Yes
15	FMOD	ENSG00000122176.12			215	3.256	0.1662	Yes
16	COL14A1	ENSG00000187955.12			257	3.107	0.1741	Yes
17	TNXB	ENSG00000168477.19			279	3.050	0.1823	Yes
18	DPT	ENSG00000143196.5			284	3.034	0.1908	Yes
19	PCOLCE2	ENSG00000163710.9			294	3.004	0.1992	Yes
20	LAMB1	ENSG00000091136.14			367	2.820	0.2055	Yes
21	COL6A3	ENSG00000163359.15			371	2.812	0.2135	Yes
22	HMCN1	ENSG00000143341.12			385	2.781	0.2211	Yes
23	SLIT2	ENSG00000145147.20			459	2.664	0.2270	Yes
24	NID1	ENSG00000116962.15			541	2.561	0.2324	Yes
25	MATN2	ENSG00000132561.14			579	2.497	0.2386	Yes
26	COL16A1	ENSG00000084636.18			589	2.483	0.2455	Yes
27	NTN1	ENSG00000065320.9			605	2.467	0.2521	Yes
28	AEBP1	ENSG00000106624.11			659	2.404	0.2577	Yes
29	SRPX	ENSG00000101955.15			660	2.402	0.2646	Yes
30	VIT	ENSG00000205221.12			783	2.278	0.2682	Yes
31	EMILIN2	ENSG00000132205.11			806	2.257	0.2741	Yes
32	COL6A2	ENSG00000142173.15			816	2.246	0.2803	Yes
33	EMILIN1	ENSG00000138080.14			864	2.201	0.2855	Yes
34	FBLN2	ENSG00000163520.14			977	2.116	0.2889	Yes
35	SVEP1	ENSG00000165124.18			984	2.111	0.2948	Yes
36	COL13A1	ENSG00000197467.14			1056	2.080	0.2990	Yes
37	RSPO1	ENSG00000169218.14			1063	2.074	0.3048	Yes
38	CCN3	ENSG00000136999.5			1071	2.068	0.3105	Yes
39	ECM1	ENSG00000143369.15			1104	2.046	0.3156	Yes
40	SNED1	ENSG00000162804.14			1129	2.032	0.3208	Yes
41	SPON2	ENSG00000159674.12			1174	2.003	0.3255	Yes
42	OMD	ENSG00000127083.7			1239	1.972	0.3296	Yes
43	IGFBP6	ENSG00000167779.9			1241	1.971	0.3352	Yes
44	LAMB4	ENSG00000091128.13			1267	1.956	0.3402	Yes
45	MFAP2	ENSG00000117122.14			1290	1.945	0.3452	Yes
46	NTNG1	ENSG00000162631.18			1308	1.933	0.3503	Yes
47	LUM	ENSG00000139329.5			1391	1.886	0.3538	Yes
48	THBS2	ENSG00000186340.15			1447	1.867	0.3578	Yes
49	LTBP4	ENSG00000090006.17			1533	1.830	0.3611	Yes
50	MATN1	ENSG00000162510.6			1553	1.817	0.3658	Yes
51	OGN	ENSG00000106809.11			1613	1.795	0.3695	Yes
52	CHAD	ENSG00000136457.10			1622	1.793	0.3744	Yes
53	COL6A1	ENSG00000142156.14			1639	1.786	0.3792	Yes
54	IGFBP3	ENSG00000146674.15			1828	1.702	0.3796	Yes
55	NDNF	ENSG00000173376.14			1863	1.685	0.3836	Yes
56	TSKU	ENSG00000182704.8			1939	1.654	0.3866	Yes
57	IGFBP5	ENSG00000115461.5			1987	1.637	0.3901	Yes
58	COL6A6	ENSG00000206384.10			2037	1.617	0.3936	Yes
59	LAMA1	ENSG00000101680.15			2061	1.609	0.3976	Yes
60	SPON1	ENSG00000262655.4			2107	1.596	0.4011	Yes
61	RSPO3	ENSG00000146374.14			2124	1.591	0.4053	Yes
62	ASPN	ENSG00000106819.13			2179	1.573	0.4085	Yes
63	CCN5	ENSG00000064205.10			2260	1.545	0.4110	Yes
64	GAS6	ENSG00000183087.15			2269	1.542	0.4153	Yes
65	MXRA5	ENSG00000101825.8			2436	1.494	0.4156	Yes
66	IGFBP2	ENSG00000115457.10			2774	1.385	0.4117	Yes
67	CCN4	ENSG00000104415.14			2781	1.383	0.4155	Yes
68	EFEMP2	ENSG00000172638.13			2973	1.339	0.4149	Yes
69	ECM2	ENSG00000106823.12			3170	1.296	0.4140	Yes
70	LTBP1	ENSG00000049323.16			3213	1.284	0.4167	Yes
71	NTN3	ENSG00000162068.2			3239	1.278	0.4197	Yes
72	MATN4	ENSG00000124159.15			3329	1.259	0.4212	Yes
73	VWF	ENSG00000110799.13			3693	1.186	0.4161	Yes
74	MGP	ENSG00000111341.10			3725	1.178	0.4188	Yes
75	GLDN	ENSG00000186417.14			3816	1.162	0.4200	Yes
76	FBLN7	ENSG00000144152.13			3897	1.146	0.4214	Yes
77	VWA2	ENSG00000165816.13			3906	1.145	0.4244	Yes
78	SMOC2	ENSG00000112562.18			3944	1.138	0.4268	Yes
79	THBS1	ENSG00000137801.11			4127	1.107	0.4257	Yes
80	IGSF10	ENSG00000152580.8			4244	1.084	0.4261	Yes
81	KCP	ENSG00000135253.13			4307	1.075	0.4277	Yes
82	TNC	ENSG00000041982.16			4396	1.062	0.4287	Yes
83	NELL2	ENSG00000184613.10			4492	1.045	0.4294	Yes
84	COL21A1	ENSG00000124749.17			4581	1.031	0.4303	Yes
85	NTN5	ENSG00000142233.11			4679	1.017	0.4310	Yes
86	LGI2	ENSG00000153012.12			4730	1.009	0.4327	Yes
87	VWA3A	ENSG00000175267.15			4988	0.970	0.4294	No
88	VWA7	ENSG00000204396.11			5110	0.953	0.4293	No
89	LGI1	ENSG00000108231.13			5517	0.899	0.4224	No
90	EFEMP1	ENSG00000115380.20			5601	0.888	0.4230	No
91	MMRN2	ENSG00000173269.14			5672	0.880	0.4239	No
92	FBN1	ENSG00000166147.13			5850	0.858	0.4222	No
93	COL27A1	ENSG00000196739.15			6103	0.828	0.4187	No
94	COMP	ENSG00000105664.11			6225	0.814	0.4182	No
95	THBS3	ENSG00000169231.13			6284	0.808	0.4191	No
96	THSD4	ENSG00000187720.14			6296	0.807	0.4211	No
97	IGFALS	ENSG00000099769.5			6320	0.805	0.4229	No
98	COL1A2	ENSG00000164692.17			6324	0.804	0.4251	No
99	COL12A1	ENSG00000111799.21			6723	0.765	0.4180	No
100	BGN	ENSG00000182492.16			7136	0.724	0.4105	No
101	COL24A1	ENSG00000171502.15			7150	0.723	0.4122	No
102	COL8A1	ENSG00000144810.16			7170	0.722	0.4138	No
103	SPOCK1	ENSG00000152377.14			7208	0.718	0.4150	No
104	COL3A1	ENSG00000168542.14			7229	0.715	0.4166	No
105	VTN	ENSG00000109072.14			7359	0.704	0.4156	No
106	FNDC8	ENSG00000073598.6			7366	0.704	0.4174	No
107	THBS4	ENSG00000113296.14			7404	0.700	0.4186	No
108	LAMC3	ENSG00000050555.18			8105	0.637	0.4040	No
109	RELN	ENSG00000189056.14			8324	0.618	0.4007	No
110	PRG2	ENSG00000186652.10			8412	0.611	0.4004	No
111	RSPO2	ENSG00000147655.12			9109	0.562	0.3858	No
112	EMILIN3	ENSG00000183798.5			9386	0.545	0.3809	No
113	OPTC	ENSG00000188770.10			9568	0.533	0.3782	No
114	FGA	ENSG00000171560.16			9683	0.524	0.3770	No
115	COL9A2	ENSG00000049089.15			9709	0.523	0.3779	No
116	MFGE8	ENSG00000140545.15			9817	0.521	0.3769	No
117	FN1	ENSG00000115414.19			9913	0.516	0.3762	No
118	LAMB2	ENSG00000172037.14			9976	0.514	0.3762	No
119	CRISPLD1	ENSG00000121005.9			10130	0.502	0.3740	No
120	PAPLN	ENSG00000100767.16			10307	0.491	0.3713	No
121	EYS	ENSG00000188107.15			10470	0.480	0.3689	No
122	CILP	ENSG00000138615.6			10643	0.469	0.3662	No
123	CILP2	ENSG00000160161.9			11030	0.442	0.3585	No
124	FBN2	ENSG00000138829.12			11219	0.432	0.3553	No
125	INTS14	ENSG00000138614.15			11455	0.416	0.3510	No
126	CCN6	ENSG00000112761.20			11461	0.416	0.3521	No
127	COL9A3	ENSG00000092758.18			11887	0.394	0.3433	No
128	ZP3	ENSG00000188372.15			12028	0.387	0.3411	No
129	FNDC7	ENSG00000143107.10			12130	0.381	0.3399	No
130	ZP1	ENSG00000149506.11			12316	0.374	0.3366	No
131	ADIPOQ	ENSG00000181092.10			12514	0.365	0.3331	No
132	HAPLN4	ENSG00000187664.9			12818	0.355	0.3270	No
133	ZP2	ENSG00000103310.10			12868	0.355	0.3269	No
134	LTBP3	ENSG00000168056.16			13216	0.345	0.3198	No
135	COL18A1	ENSG00000182871.16			13315	0.339	0.3184	No
136	COL23A1	ENSG00000050767.17			13999	0.317	0.3034	No
137	FGL2	ENSG00000127951.7			14791	0.292	0.2858	No
138	DMP1	ENSG00000152592.14			14902	0.287	0.2840	No
139	SPARCL1	ENSG00000152583.12			15335	0.283	0.2747	No
140	SSPO	ENSG00000197558.12			15851	0.257	0.2635	No
141	IMPG1	ENSG00000112706.12			16028	0.247	0.2601	No
142	PXDNL	ENSG00000147485.13			16046	0.246	0.2604	No
143	ANOS1	ENSG00000011201.12			16273	0.231	0.2557	No
144	AMELX	ENSG00000125363.14			16753	0.208	0.2452	No
145	EMID1	ENSG00000186998.16			17267	0.185	0.2337	No
146	COL15A1	ENSG00000204291.11			18002	0.146	0.2170	No
147	INTS6L	ENSG00000165359.15			18138	0.139	0.2142	No
148	SLIT1	ENSG00000187122.17			18654	0.116	0.2026	No
149	RSPO4	ENSG00000101282.9			18734	0.111	0.2010	No
150	LGI3	ENSG00000168481.9			19647	0.064	0.1799	No
151	CRISPLD2	ENSG00000103196.12			19779	0.057	0.1770	No
152	COL4A5	ENSG00000188153.13			20097	0.043	0.1698	No
153	LGI4	ENSG00000153902.14			20108	0.042	0.1696	No
154	COL8A2	ENSG00000171812.13			20347	0.029	0.1642	No
155	SPP1	ENSG00000118785.14			20575	0.018	0.1589	No
156	ACAN	ENSG00000157766.17			20782	0.008	0.1541	No
157	PODNL1	ENSG00000132000.13			22171	-0.066	0.1219	No
158	CCN1	ENSG00000142871.17			22390	-0.079	0.1171	No
159	SPOCK3	ENSG00000196104.11			22407	-0.079	0.1169	No
160	LAMC1	ENSG00000135862.6			22432	-0.081	0.1166	No
161	LAMA2	ENSG00000196569.12			22603	-0.091	0.1129	No
162	FGG	ENSG00000171557.17			22680	-0.095	0.1114	No
163	COL6A5	ENSG00000172752.14			22980	-0.111	0.1047	No
164	COL9A1	ENSG00000112280.16			23057	-0.115	0.1033	No
165	FNDC1	ENSG00000164694.17			23291	-0.129	0.0982	No
166	NYX	ENSG00000188937.5			24981	-0.223	0.0594	No
167	MEPE	ENSG00000152595.16			25833	-0.250	0.0403	No
168	AGRN	ENSG00000188157.15			25926	-0.255	0.0389	No
169	TSPEAR	ENSG00000175894.18			26499	-0.266	0.0263	No
170	MMRN1	ENSG00000138722.10			26727	-0.275	0.0218	No
171	OTOL1	ENSG00000182447.4			26871	-0.275	0.0192	No
172	CRIM1	ENSG00000150938.10			27020	-0.275	0.0165	No
173	VWA5B2	ENSG00000145198.14			27302	-0.295	0.0108	No
174	AMBN	ENSG00000178522.14			27454	-0.297	0.0082	No
175	COL5A3	ENSG00000080573.7			27521	-0.299	0.0075	No
176	VWA3B	ENSG00000168658.19			27943	-0.305	-0.0015	No
177	DSPP	ENSG00000152591.15			28022	-0.311	-0.0024	No
178	CHADL	ENSG00000100399.16			28291	-0.329	-0.0077	No
179	PXDN	ENSG00000130508.11			29709	-0.387	-0.0397	No
180	TINAGL1	ENSG00000142910.16			29866	-0.395	-0.0422	No
181	TNR	ENSG00000116147.17			29931	-0.401	-0.0426	No
182	VWA1	ENSG00000179403.12			29936	-0.402	-0.0415	No
183	SBSPON	ENSG00000164764.11			29941	-0.402	-0.0405	No
184	NTNG2	ENSG00000196358.11			30172	-0.419	-0.0447	No
185	POMZP3	ENSG00000146707.14			30425	-0.433	-0.0493	No
186	COL4A6	ENSG00000197565.15			31285	-0.477	-0.0680	No
187	NCAN	ENSG00000130287.14			31294	-0.478	-0.0668	No
188	COCH	ENSG00000100473.18			31549	-0.493	-0.0713	No
189	COL11A2	ENSG00000204248.10			31819	-0.502	-0.0762	No
190	LTBP2	ENSG00000119681.12			31926	-0.510	-0.0772	No
191	HAPLN1	ENSG00000145681.11			31977	-0.511	-0.0769	No
192	COL1A1	ENSG00000108821.13			32343	-0.536	-0.0839	No
193	SPOCK2	ENSG00000107742.13			32816	-0.570	-0.0933	No
194	CCN2	ENSG00000118523.6			32823	-0.570	-0.0918	No
195	LAMA3	ENSG00000053747.16			32988	-0.582	-0.0940	No
196	PRG4	ENSG00000116690.12			33040	-0.586	-0.0935	No
197	HAPLN2	ENSG00000132702.13			33065	-0.588	-0.0924	No
198	POSTN	ENSG00000133110.15			33395	-0.612	-0.0983	No
199	COL10A1	ENSG00000123500.10			33676	-0.637	-0.1030	No
200	EDIL3	ENSG00000164176.13			33729	-0.640	-0.1024	No
201	COL17A1	ENSG00000065618.21			33743	-0.641	-0.1009	No
202	VWA5B1	ENSG00000158816.15			33860	-0.650	-0.1018	No
203	COL4A3	ENSG00000169031.19			34183	-0.675	-0.1074	No
204	FBN3	ENSG00000142449.13			34259	-0.679	-0.1072	No
205	VWDE	ENSG00000146530.14			34944	-0.738	-0.1210	No
206	USH2A	ENSG00000042781.13			35129	-0.754	-0.1232	No
207	ESM1	ENSG00000164283.13			35274	-0.765	-0.1244	No
208	ABI3BP	ENSG00000154175.17			35307	-0.769	-0.1229	No
209	MFAP1	ENSG00000140259.7			36107	-0.857	-0.1391	No
210	VCAN	ENSG00000038427.16			36187	-0.866	-0.1385	No
211	CRELD2	ENSG00000184164.14			36510	-0.902	-0.1435	No
212	COL5A2	ENSG00000204262.14			36764	-0.936	-0.1467	No
213	ELN	ENSG00000049540.17			37004	-0.966	-0.1495	No
214	SPARC	ENSG00000113140.11			37052	-0.974	-0.1478	No
215	NID2	ENSG00000087303.18			37054	-0.975	-0.1451	No
216	COL5A1	ENSG00000130635.15			37069	-0.977	-0.1426	No
217	FRAS1	ENSG00000138759.19			37156	-0.987	-0.1418	No
218	EPYC	ENSG00000083782.8			37354	-1.014	-0.1435	No
219	TNFAIP6	ENSG00000123610.5			37407	-1.021	-0.1418	No
220	LAMC2	ENSG00000058085.15			37414	-1.022	-0.1391	No
221	HAPLN3	ENSG00000140511.11			37514	-1.036	-0.1384	No
222	SMOC1	ENSG00000198732.10			37952	-1.109	-0.1455	No
223	COL28A1	ENSG00000215018.10			38490	-1.204	-0.1546	No
224	COLQ	ENSG00000206561.13			38666	-1.236	-0.1551	No
225	MFAP5	ENSG00000197614.11			38668	-1.237	-0.1516	No
226	BGLAP	ENSG00000242252.2			38699	-1.243	-0.1488	No
227	IBSP	ENSG00000029559.7			38893	-1.288	-0.1496	No
228	TECTB	ENSG00000119913.6			38943	-1.297	-0.1471	No
229	COL4A4	ENSG00000081052.12			39066	-1.323	-0.1462	No
230	COL4A1	ENSG00000187498.16			39310	-1.380	-0.1479	No
231	COL7A1	ENSG00000114270.17			39421	-1.404	-0.1465	No
232	COL4A2	ENSG00000134871.19			39460	-1.413	-0.1434	No
233	NELL1	ENSG00000165973.19			39509	-1.424	-0.1404	No
234	OIT3	ENSG00000138315.13			39527	-1.426	-0.1368	No
235	IGFBP7	ENSG00000163453.11			39937	-1.531	-0.1419	No
236	SRPX2	ENSG00000102359.7			39993	-1.546	-0.1388	No
237	MATN3	ENSG00000132031.13			40083	-1.566	-0.1364	No
238	HSPG2	ENSG00000142798.20			40144	-1.586	-0.1333	No
239	COL22A1	ENSG00000169436.17			40149	-1.586	-0.1289	No
240	LAMB3	ENSG00000196878.15			40157	-1.589	-0.1245	No
241	IGFBP1	ENSG00000146678.10			40197	-1.599	-0.1209	No
242	COL11A1	ENSG00000060718.22			40275	-1.618	-0.1181	No
243	HMCN2	ENSG00000148357.16			40680	-1.743	-0.1225	No
244	TGFBI	ENSG00000120708.17			40715	-1.752	-0.1184	No
245	COL2A1	ENSG00000139219.19			40754	-1.768	-0.1142	No
246	COL25A1	ENSG00000188517.16			40900	-1.824	-0.1124	No
247	NTN4	ENSG00000074527.12			40972	-1.850	-0.1088	No
248	CRELD1	ENSG00000163703.17			40973	-1.851	-0.1035	No
249	MFAP3	ENSG00000037749.12			41206	-1.961	-0.1033	No
250	TECTA	ENSG00000109927.10			41250	-1.977	-0.0987	No
251	VWA5A	ENSG00000110002.16			41384	-2.054	-0.0960	No
252	COL19A1	ENSG00000082293.13			41431	-2.090	-0.0911	No
253	COL20A1	ENSG00000101203.16			41443	-2.097	-0.0854	No
254	SRGN	ENSG00000122862.5			41600	-2.195	-0.0828	No
255	TNN	ENSG00000120332.16			41639	-2.216	-0.0773	No
256	ZPLD1	ENSG00000170044.8			41688	-2.241	-0.0721	No
257	KERA	ENSG00000139330.5			41696	-2.249	-0.0658	No
258	TINAG	ENSG00000137251.16			41783	-2.314	-0.0613	No
259	IMPG2	ENSG00000081148.12			42135	-2.622	-0.0620	No
260	LRG1	ENSG00000171236.10			42146	-2.634	-0.0547	No
261	DMBT1	ENSG00000187908.19			42199	-2.691	-0.0483	No
262	LAMA5	ENSG00000130702.15			42431	-3.030	-0.0450	No
263	NPNT	ENSG00000168743.12			42684	-3.542	-0.0408	No
264	EGFLAM	ENSG00000164318.18			42765	-3.770	-0.0320	No
265	BCAN	ENSG00000132692.19			42962	-4.544	-0.0236	No
266	OTOG	ENSG00000188162.11			43012	-4.761	-0.0112	No
267	IGFBPL1	ENSG00000137142.5			43020	-4.797	0.0023	No

Fig 2: NABA_CORE_MATRISOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: NABA_CORE_MATRISOME: Random ES distribution   
Gene set null distribution of ES for NABA_CORE_MATRISOME