Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | PID_IL1_PATHWAY |
| Enrichment Score (ES) | 0.5406611 |
| Normalized Enrichment Score (NES) | 1.815786 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.031881012 |
| FWER p-Value | 0.669 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PIK3R1 | ENSG00000145675.15 | 513 | 2.587 | 0.0674 | Yes | ||
| 2 | IL1R1 | ENSG00000115594.12 | 542 | 2.559 | 0.1452 | Yes | ||
| 3 | IRAK3 | ENSG00000090376.11 | 790 | 2.273 | 0.2092 | Yes | ||
| 4 | MAP3K3 | ENSG00000198909.7 | 1502 | 1.843 | 0.2492 | Yes | ||
| 5 | SQSTM1 | ENSG00000161011.20 | 1557 | 1.815 | 0.3036 | Yes | ||
| 6 | IL1RN | ENSG00000136689.18 | 1638 | 1.787 | 0.3565 | Yes | ||
| 7 | MYD88 | ENSG00000172936.14 | 2301 | 1.535 | 0.3882 | Yes | ||
| 8 | IL1R2 | ENSG00000115590.14 | 2747 | 1.394 | 0.4206 | Yes | ||
| 9 | PRKCZ | ENSG00000067606.17 | 2794 | 1.380 | 0.4618 | Yes | ||
| 10 | CASP1 | ENSG00000137752.24 | 2840 | 1.369 | 0.5027 | Yes | ||
| 11 | MAP2K6 | ENSG00000108984.15 | 3826 | 1.160 | 0.5154 | Yes | ||
| 12 | IRAK4 | ENSG00000198001.13 | 4188 | 1.096 | 0.5407 | Yes | ||
| 13 | NFKB1 | ENSG00000109320.13 | 6111 | 0.828 | 0.5214 | No | ||
| 14 | IL1A | ENSG00000115008.5 | 10008 | 0.511 | 0.4467 | No | ||
| 15 | TAB1 | ENSG00000100324.14 | 11100 | 0.438 | 0.4348 | No | ||
| 16 | IKBKG | ENSG00000269335.5 | 11365 | 0.423 | 0.4416 | No | ||
| 17 | TOLLIP | ENSG00000078902.16 | 14850 | 0.289 | 0.3696 | No | ||
| 18 | IL1B | ENSG00000125538.12 | 17487 | 0.172 | 0.3137 | No | ||
| 19 | IRAK1 | ENSG00000184216.14 | 18454 | 0.127 | 0.2952 | No | ||
| 20 | RELA | ENSG00000173039.19 | 18880 | 0.104 | 0.2885 | No | ||
| 21 | PIK3CA | ENSG00000121879.5 | 19940 | 0.051 | 0.2655 | No | ||
| 22 | UBE2V1 | ENSG00000244687.11 | 20086 | 0.043 | 0.2635 | No | ||
| 23 | TICAM2 | ENSG00000243414.5 | 21781 | -0.046 | 0.2256 | No | ||
| 24 | IL1RAP | ENSG00000196083.10 | 22658 | -0.094 | 0.2081 | No | ||
| 25 | CHUK | ENSG00000213341.11 | 24032 | -0.173 | 0.1815 | No | ||
| 26 | ERC1 | ENSG00000082805.20 | 29082 | -0.352 | 0.0751 | No | ||
| 27 | TAB2 | ENSG00000055208.19 | 31004 | -0.460 | 0.0447 | No | ||
| 28 | PRKCI | ENSG00000163558.13 | 32282 | -0.533 | 0.0314 | No | ||
| 29 | IKBKB | ENSG00000104365.15 | 33503 | -0.622 | 0.0221 | No | ||
| 30 | TRAF6 | ENSG00000175104.15 | 36390 | -0.887 | -0.0177 | No | ||
| 31 | JUN | ENSG00000177606.7 | 37141 | -0.985 | -0.0049 | No | ||
| 32 | UBE2N | ENSG00000177889.10 | 38590 | -1.222 | -0.0011 | No | ||
| 33 | MAP3K7 | ENSG00000135341.18 | 40323 | -1.633 | 0.0088 | No | ||
| 34 | MAPK8 | ENSG00000107643.16 | 40914 | -1.829 | 0.0512 | No |
