Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS |
| Enrichment Score (ES) | -0.68579245 |
| Normalized Enrichment Score (NES) | -2.0061915 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011818652 |
| FWER p-Value | 0.038 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPT | ENSG00000186868.15 | 2157 | 1.580 | -0.0086 | No | ||
| 2 | TUBA3D | ENSG00000075886.11 | 4260 | 1.082 | -0.0289 | No | ||
| 3 | CAMKK2 | ENSG00000110931.19 | 5251 | 0.934 | -0.0274 | No | ||
| 4 | PRKAG1 | ENSG00000181929.13 | 6839 | 0.753 | -0.0444 | No | ||
| 5 | PRKAA1 | ENSG00000132356.11 | 11381 | 0.422 | -0.1387 | No | ||
| 6 | PRKAB1 | ENSG00000111725.11 | 16157 | 0.239 | -0.2433 | No | ||
| 7 | TUBA3E | ENSG00000152086.9 | 19116 | 0.094 | -0.3094 | No | ||
| 8 | TUBA4B | ENSG00000243910.8 | 20489 | 0.024 | -0.3407 | No | ||
| 9 | TUBB1 | ENSG00000101162.3 | 20635 | 0.015 | -0.3436 | No | ||
| 10 | TUBA3C | ENSG00000198033.12 | 25534 | -0.229 | -0.4513 | No | ||
| 11 | TUBA8 | ENSG00000183785.15 | 28485 | -0.335 | -0.5109 | No | ||
| 12 | TUBB8 | ENSG00000261456.5 | 29700 | -0.387 | -0.5290 | No | ||
| 13 | TUBB3 | ENSG00000258947.7 | 30130 | -0.416 | -0.5280 | No | ||
| 14 | TUBB4A | ENSG00000104833.12 | 30148 | -0.417 | -0.5174 | No | ||
| 15 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.6590 | Yes | ||
| 16 | TUBA1B | ENSG00000123416.15 | 37968 | -1.112 | -0.6428 | Yes | ||
| 17 | TUBB2A | ENSG00000137267.6 | 38477 | -1.201 | -0.6231 | Yes | ||
| 18 | TUBB2B | ENSG00000137285.10 | 38935 | -1.296 | -0.5996 | Yes | ||
| 19 | TUBB4B | ENSG00000188229.6 | 40254 | -1.615 | -0.5878 | Yes | ||
| 20 | PRKAG2 | ENSG00000106617.14 | 41635 | -2.213 | -0.5617 | Yes | ||
| 21 | TUBA1C | ENSG00000167553.15 | 41915 | -2.420 | -0.5047 | Yes | ||
| 22 | PRKAA2 | ENSG00000162409.11 | 41921 | -2.424 | -0.4411 | Yes | ||
| 23 | CALM1 | ENSG00000198668.12 | 42323 | -2.877 | -0.3749 | Yes | ||
| 24 | PRKAB2 | ENSG00000131791.8 | 42379 | -2.953 | -0.2986 | Yes | ||
| 25 | TUBA1A | ENSG00000167552.14 | 42574 | -3.253 | -0.2177 | Yes | ||
| 26 | TUBB6 | ENSG00000176014.13 | 42804 | -3.928 | -0.1198 | Yes | ||
| 27 | PRKAG3 | ENSG00000115592.11 | 43035 | -4.840 | 0.0019 | Yes |
