Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 |
| Enrichment Score (ES) | -0.5755916 |
| Normalized Enrichment Score (NES) | -2.014794 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011557246 |
| FWER p-Value | 0.036 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB9 | ENSG00000240065.8 | 653 | 2.409 | 0.0213 | No | ||
| 2 | PSMB8 | ENSG00000204264.11 | 1023 | 2.095 | 0.0444 | No | ||
| 3 | PSMB10 | ENSG00000205220.12 | 3086 | 1.313 | 0.0163 | No | ||
| 4 | CDC26 | ENSG00000176386.9 | 7372 | 0.703 | -0.0726 | No | ||
| 5 | ANAPC16 | ENSG00000166295.9 | 8822 | 0.582 | -0.0974 | No | ||
| 6 | UBA52 | ENSG00000221983.8 | 9987 | 0.512 | -0.1167 | No | ||
| 7 | PSMA2 | ENSG00000106588.11 | 16418 | 0.224 | -0.2627 | No | ||
| 8 | UBB | ENSG00000170315.14 | 17176 | 0.189 | -0.2774 | No | ||
| 9 | PSME1 | ENSG00000092010.15 | 17744 | 0.161 | -0.2882 | No | ||
| 10 | ANAPC4 | ENSG00000053900.10 | 19109 | 0.094 | -0.3184 | No | ||
| 11 | ANAPC5 | ENSG00000089053.13 | 19924 | 0.051 | -0.3366 | No | ||
| 12 | PSMF1 | ENSG00000125818.18 | 20560 | 0.019 | -0.3510 | No | ||
| 13 | SEM1 | ENSG00000127922.9 | 21274 | -0.020 | -0.3673 | No | ||
| 14 | ANAPC10 | ENSG00000164162.14 | 21601 | -0.037 | -0.3743 | No | ||
| 15 | UBC | ENSG00000150991.15 | 21944 | -0.054 | -0.3814 | No | ||
| 16 | CCNE2 | ENSG00000175305.17 | 21963 | -0.055 | -0.3810 | No | ||
| 17 | UBE2D1 | ENSG00000072401.15 | 22471 | -0.083 | -0.3916 | No | ||
| 18 | CDC16 | ENSG00000130177.16 | 23003 | -0.112 | -0.4022 | No | ||
| 19 | PSMD9 | ENSG00000110801.14 | 23060 | -0.115 | -0.4017 | No | ||
| 20 | PSMD5 | ENSG00000095261.14 | 23841 | -0.161 | -0.4174 | No | ||
| 21 | RPS27A | ENSG00000143947.13 | 24249 | -0.185 | -0.4241 | No | ||
| 22 | PSMA8 | ENSG00000154611.14 | 26134 | -0.263 | -0.4639 | No | ||
| 23 | PSMB11 | ENSG00000222028.5 | 27828 | -0.302 | -0.4986 | No | ||
| 24 | ANAPC2 | ENSG00000176248.9 | 27964 | -0.306 | -0.4971 | No | ||
| 25 | PSMB3 | ENSG00000277791.5 | 29269 | -0.361 | -0.5220 | No | ||
| 26 | PSMA1 | ENSG00000129084.17 | 30662 | -0.448 | -0.5475 | No | ||
| 27 | PSME3 | ENSG00000131467.11 | 30737 | -0.449 | -0.5425 | No | ||
| 28 | PSMA3 | ENSG00000100567.13 | 31911 | -0.509 | -0.5620 | No | ||
| 29 | FZR1 | ENSG00000105325.14 | 31978 | -0.512 | -0.5558 | No | ||
| 30 | CDC27 | ENSG00000004897.12 | 32830 | -0.571 | -0.5670 | Yes | ||
| 31 | PSMB1 | ENSG00000008018.9 | 33034 | -0.586 | -0.5628 | Yes | ||
| 32 | PSMD13 | ENSG00000185627.18 | 33437 | -0.616 | -0.5628 | Yes | ||
| 33 | PSMB4 | ENSG00000159377.11 | 33581 | -0.627 | -0.5567 | Yes | ||
| 34 | PSME2 | ENSG00000100911.16 | 33632 | -0.632 | -0.5483 | Yes | ||
| 35 | PSMD10 | ENSG00000101843.19 | 33841 | -0.648 | -0.5433 | Yes | ||
| 36 | CCNA1 | ENSG00000133101.10 | 34815 | -0.726 | -0.5549 | Yes | ||
| 37 | UBE2C | ENSG00000175063.17 | 34985 | -0.740 | -0.5477 | Yes | ||
| 38 | CCNA2 | ENSG00000145386.10 | 35426 | -0.780 | -0.5461 | Yes | ||
| 39 | PSMC5 | ENSG00000087191.13 | 35455 | -0.783 | -0.5349 | Yes | ||
| 40 | ANAPC1 | ENSG00000153107.13 | 35605 | -0.799 | -0.5263 | Yes | ||
| 41 | PSMA7 | ENSG00000101182.15 | 35709 | -0.810 | -0.5164 | Yes | ||
| 42 | PSMB2 | ENSG00000126067.12 | 35837 | -0.822 | -0.5069 | Yes | ||
| 43 | PSMA5 | ENSG00000143106.13 | 36170 | -0.865 | -0.5016 | Yes | ||
| 44 | UBE2E1 | ENSG00000170142.12 | 36422 | -0.891 | -0.4939 | Yes | ||
| 45 | PSMC2 | ENSG00000161057.12 | 36487 | -0.899 | -0.4818 | Yes | ||
| 46 | PSMB7 | ENSG00000136930.13 | 36803 | -0.941 | -0.4749 | Yes | ||
| 47 | CDC23 | ENSG00000094880.11 | 36926 | -0.956 | -0.4633 | Yes | ||
| 48 | CDK2 | ENSG00000123374.11 | 37047 | -0.974 | -0.4513 | Yes | ||
| 49 | PSMB6 | ENSG00000142507.10 | 37064 | -0.976 | -0.4369 | Yes | ||
| 50 | PSMA4 | ENSG00000041357.16 | 38333 | -1.177 | -0.4486 | Yes | ||
| 51 | PSMB5 | ENSG00000100804.19 | 38565 | -1.217 | -0.4356 | Yes | ||
| 52 | PSMD7 | ENSG00000103035.11 | 38868 | -1.282 | -0.4232 | Yes | ||
| 53 | ANAPC7 | ENSG00000196510.12 | 38905 | -1.290 | -0.4045 | Yes | ||
| 54 | ANAPC11 | ENSG00000141552.17 | 39180 | -1.349 | -0.3905 | Yes | ||
| 55 | PSMD6 | ENSG00000163636.10 | 39440 | -1.407 | -0.3752 | Yes | ||
| 56 | PSMA6 | ENSG00000100902.11 | 39610 | -1.444 | -0.3573 | Yes | ||
| 57 | PSMD3 | ENSG00000108344.15 | 39660 | -1.456 | -0.3364 | Yes | ||
| 58 | PSMD4 | ENSG00000159352.15 | 39708 | -1.468 | -0.3153 | Yes | ||
| 59 | ANAPC15 | ENSG00000110200.8 | 39750 | -1.479 | -0.2939 | Yes | ||
| 60 | PSMC1 | ENSG00000100764.14 | 39751 | -1.479 | -0.2715 | Yes | ||
| 61 | PSMD12 | ENSG00000197170.10 | 40160 | -1.590 | -0.2569 | Yes | ||
| 62 | PSMD8 | ENSG00000099341.11 | 40314 | -1.631 | -0.2358 | Yes | ||
| 63 | PSMC4 | ENSG00000013275.8 | 40405 | -1.659 | -0.2128 | Yes | ||
| 64 | PSMD11 | ENSG00000108671.11 | 40619 | -1.724 | -0.1917 | Yes | ||
| 65 | PSMD14 | ENSG00000115233.12 | 40751 | -1.767 | -0.1680 | Yes | ||
| 66 | PSMC6 | ENSG00000100519.12 | 40791 | -1.783 | -0.1419 | Yes | ||
| 67 | CCNE1 | ENSG00000105173.14 | 41239 | -1.974 | -0.1225 | Yes | ||
| 68 | PSMD1 | ENSG00000173692.13 | 41284 | -1.994 | -0.0933 | Yes | ||
| 69 | PSMC3 | ENSG00000165916.8 | 41467 | -2.112 | -0.0656 | Yes | ||
| 70 | CDC6 | ENSG00000094804.12 | 41614 | -2.200 | -0.0357 | Yes | ||
| 71 | PSME4 | ENSG00000068878.15 | 41799 | -2.328 | -0.0048 | Yes | ||
| 72 | PSMD2 | ENSG00000175166.17 | 41820 | -2.343 | 0.0302 | Yes |
