Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_CHOLESTEROL_BIOSYNTHESIS |
| Enrichment Score (ES) | 0.7411786 |
| Normalized Enrichment Score (NES) | 2.2854617 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | ENSG00000116133.13 | 91 | 3.768 | 0.1098 | Yes | ||
| 2 | LSS | ENSG00000160285.15 | 553 | 2.538 | 0.1744 | Yes | ||
| 3 | SQLE | ENSG00000104549.12 | 823 | 2.241 | 0.2347 | Yes | ||
| 4 | CYP51A1 | ENSG00000001630.17 | 829 | 2.232 | 0.3009 | Yes | ||
| 5 | ACAT2 | ENSG00000120437.9 | 847 | 2.219 | 0.3664 | Yes | ||
| 6 | HMGCR | ENSG00000113161.16 | 1456 | 1.862 | 0.4075 | Yes | ||
| 7 | MSMO1 | ENSG00000052802.13 | 1692 | 1.758 | 0.4543 | Yes | ||
| 8 | MVK | ENSG00000110921.14 | 1775 | 1.727 | 0.5037 | Yes | ||
| 9 | HSD17B7 | ENSG00000132196.14 | 1994 | 1.633 | 0.5471 | Yes | ||
| 10 | PLPP6 | ENSG00000205808.6 | 2085 | 1.603 | 0.5926 | Yes | ||
| 11 | HMGCS1 | ENSG00000112972.15 | 2715 | 1.404 | 0.6197 | Yes | ||
| 12 | MVD | ENSG00000167508.12 | 3276 | 1.273 | 0.6445 | Yes | ||
| 13 | FDPS | ENSG00000160752.14 | 3502 | 1.225 | 0.6756 | Yes | ||
| 14 | DHCR7 | ENSG00000172893.15 | 3663 | 1.193 | 0.7073 | Yes | ||
| 15 | FDFT1 | ENSG00000079459.13 | 3715 | 1.180 | 0.7412 | Yes | ||
| 16 | TM7SF2 | ENSG00000149809.15 | 6196 | 0.817 | 0.7079 | No | ||
| 17 | NSDHL | ENSG00000147383.11 | 7604 | 0.679 | 0.6954 | No | ||
| 18 | LBR | ENSG00000143815.15 | 8417 | 0.611 | 0.6947 | No | ||
| 19 | EBP | ENSG00000147155.11 | 9521 | 0.536 | 0.6850 | No | ||
| 20 | GGPS1 | ENSG00000152904.11 | 10416 | 0.484 | 0.6787 | No | ||
| 21 | IDI1 | ENSG00000067064.11 | 20014 | 0.048 | 0.4574 | No | ||
| 22 | IDI2 | ENSG00000148377.6 | 31693 | -0.497 | 0.2012 | No | ||
| 23 | ARV1 | ENSG00000173409.14 | 33238 | -0.601 | 0.1832 | No | ||
| 24 | SC5D | ENSG00000109929.10 | 34365 | -0.689 | 0.1775 | No | ||
| 25 | PMVK | ENSG00000163344.6 | 36154 | -0.862 | 0.1616 | No |
