Details for gene set REACTOME_COMPLEMENT

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	REACTOME_COMPLEMENT_CASCADE
Enrichment Score (ES)	0.49139106
Normalized Enrichment Score (NES)	1.871737
Nominal p-value	0.0
FDR q-value	0.019802848
FWER p-Value	0.417

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1S	ENSG00000182326.15	34	4.267	0.0657	Yes
2	MASP1	ENSG00000127241.16	191	3.323	0.1139	Yes
3	CFB	ENSG00000243649.8	196	3.306	0.1654	Yes
4	C1R	ENSG00000159403.18	251	3.121	0.2128	Yes
5	C5	ENSG00000106804.7	443	2.687	0.2502	Yes
6	ELANE	ENSG00000197561.7	623	2.444	0.2842	Yes
7	PROS1	ENSG00000184500.15	997	2.107	0.3083	Yes
8	CD81	ENSG00000110651.11	1137	2.025	0.3367	Yes
9	CD46	ENSG00000117335.19	1590	1.805	0.3543	Yes
10	CD59	ENSG00000085063.16	1662	1.770	0.3803	Yes
11	CFD	ENSG00000197766.8	1895	1.671	0.4009	Yes
12	CLU	ENSG00000120885.22	2415	1.500	0.4123	Yes
13	FCN3	ENSG00000142748.12	2884	1.360	0.4226	Yes
14	C8G	ENSG00000176919.13	2959	1.343	0.4418	Yes
15	SERPING1	ENSG00000149131.15	3087	1.313	0.4593	Yes
16	MASP2	ENSG00000009724.17	3469	1.231	0.4697	Yes
17	C3	ENSG00000125730.17	4292	1.078	0.4674	Yes
18	CR1	ENSG00000203710.11	5061	0.959	0.4645	Yes
19	CD55	ENSG00000196352.15	5115	0.952	0.4781	Yes
20	CPN2	ENSG00000178772.7	5178	0.943	0.4914	Yes
21	C5AR2	ENSG00000134830.6	6930	0.744	0.4623	No
22	VTN	ENSG00000109072.14	7359	0.704	0.4634	No
23	C4BPB	ENSG00000123843.13	7483	0.692	0.4713	No
24	CFH	ENSG00000000971.15	8408	0.612	0.4594	No
25	FCN1	ENSG00000085265.11	8484	0.608	0.4671	No
26	COLEC10	ENSG00000184374.3	8818	0.582	0.4684	No
27	C4A	ENSG00000244731.8	8939	0.572	0.4746	No
28	COLEC11	ENSG00000118004.17	10366	0.487	0.4490	No
29	C2	ENSG00000166278.15	10689	0.466	0.4488	No
30	CD19	ENSG00000177455.14	12407	0.369	0.4147	No
31	CFHR4	ENSG00000134365.13	13070	0.350	0.4048	No
32	MBL2	ENSG00000165471.6	13582	0.322	0.3979	No
33	CFHR2	ENSG00000080910.13	13602	0.322	0.4025	No
34	CFHR5	ENSG00000134389.9	13603	0.322	0.4075	No
35	C5AR1	ENSG00000197405.8	14141	0.308	0.3999	No
36	CRP	ENSG00000132693.12	14159	0.308	0.4043	No
37	C8A	ENSG00000157131.10	14876	0.287	0.3921	No
38	C4BPA	ENSG00000123838.11	16021	0.248	0.3694	No
39	CFHR1	ENSG00000244414.6	16317	0.229	0.3661	No
40	IGLV1-51	ENSG00000211644.3	18272	0.132	0.3228	No
41	C8B	ENSG00000021852.13	18843	0.105	0.3112	No
42	IGLV3-1	ENSG00000211673.2	20202	0.037	0.2803	No
43	CFP	ENSG00000126759.13	21023	-0.005	0.2613	No
44	CFHR3	ENSG00000116785.13	21936	-0.053	0.2409	No
45	C4B	ENSG00000224389.9	23628	-0.148	0.2040	No
46	IGHG2	ENSG00000211893.4	24912	-0.223	0.1776	No
47	C6	ENSG00000039537.13	25989	-0.260	0.1567	No
48	IGHG1	ENSG00000211896.7	26070	-0.263	0.1589	No
49	IGHV3-7	ENSG00000211938.2	27473	-0.297	0.1310	No
50	C1QA	ENSG00000173372.17	28844	-0.351	0.1047	No
51	IGLV7-43	ENSG00000211652.2	29019	-0.351	0.1061	No
52	GZMM	ENSG00000197540.8	29690	-0.386	0.0966	No
53	CR2	ENSG00000117322.17	31514	-0.489	0.0619	No
54	IGLC3	ENSG00000211679.2	31713	-0.498	0.0650	No
55	FCN2	ENSG00000160339.16	32052	-0.518	0.0652	No
56	CPB2	ENSG00000080618.16	32522	-0.544	0.0628	No
57	IGLV1-40	ENSG00000211653.2	34383	-0.691	0.0304	No
58	IGLV1-44	ENSG00000211651.3	34889	-0.732	0.0301	No
59	C9	ENSG00000113600.11	35681	-0.807	0.0243	No
60	IGLC2	ENSG00000211677.2	38878	-1.284	-0.0299	No
61	C7	ENSG00000112936.19	39983	-1.544	-0.0315	No
62	CFI	ENSG00000205403.13	40164	-1.591	-0.0109	No
63	F2	ENSG00000180210.14	41777	-2.308	-0.0123	No
64	C3AR1	ENSG00000171860.5	42263	-2.787	0.0199	No