Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_ENDOGENOUS_STEROLS |
| Enrichment Score (ES) | 0.56982595 |
| Normalized Enrichment Score (NES) | 1.7740344 |
| Nominal p-value | 0.00477327 |
| FDR q-value | 0.040227614 |
| FWER p-Value | 0.822 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CYP27A1 | ENSG00000135929.9 | 400 | 2.753 | 0.0710 | Yes | ||
| 2 | AHR | ENSG00000106546.14 | 498 | 2.602 | 0.1447 | Yes | ||
| 3 | CYP51A1 | ENSG00000001630.17 | 829 | 2.232 | 0.2022 | Yes | ||
| 4 | CYP11A1 | ENSG00000140459.18 | 920 | 2.156 | 0.2630 | Yes | ||
| 5 | CYP7B1 | ENSG00000172817.4 | 995 | 2.108 | 0.3228 | Yes | ||
| 6 | RXRA | ENSG00000186350.12 | 1332 | 1.918 | 0.3710 | Yes | ||
| 7 | FDXR | ENSG00000161513.12 | 1927 | 1.658 | 0.4056 | Yes | ||
| 8 | PTGIS | ENSG00000124212.6 | 2119 | 1.592 | 0.4476 | Yes | ||
| 9 | CYP4V2 | ENSG00000145476.16 | 2229 | 1.555 | 0.4905 | Yes | ||
| 10 | AHRR | ENSG00000063438.17 | 2577 | 1.448 | 0.5247 | Yes | ||
| 11 | CYP7A1 | ENSG00000167910.4 | 3605 | 1.205 | 0.5360 | Yes | ||
| 12 | NCOA2 | ENSG00000140396.13 | 3691 | 1.187 | 0.5686 | Yes | ||
| 13 | CYP19A1 | ENSG00000137869.15 | 4946 | 0.977 | 0.5680 | Yes | ||
| 14 | FDX1 | ENSG00000137714.3 | 5937 | 0.849 | 0.5698 | Yes | ||
| 15 | CYP1B1 | ENSG00000138061.12 | 7105 | 0.727 | 0.5640 | No | ||
| 16 | FDX2 | ENSG00000267673.6 | 10225 | 0.495 | 0.5061 | No | ||
| 17 | CYP39A1 | ENSG00000146233.8 | 12375 | 0.371 | 0.4670 | No | ||
| 18 | CYP21A2 | ENSG00000231852.9 | 13927 | 0.321 | 0.4404 | No | ||
| 19 | ARNT | ENSG00000143437.21 | 16305 | 0.230 | 0.3919 | No | ||
| 20 | POMC | ENSG00000115138.11 | 18442 | 0.128 | 0.3461 | No | ||
| 21 | NR1H4 | ENSG00000012504.15 | 24416 | -0.194 | 0.2132 | No | ||
| 22 | CYP8B1 | ENSG00000180432.6 | 34531 | -0.704 | -0.0010 | No | ||
| 23 | NCOA1 | ENSG00000084676.15 | 39735 | -1.475 | -0.0787 | No | ||
| 24 | ARNT2 | ENSG00000172379.21 | 40803 | -1.786 | -0.0513 | No | ||
| 25 | CYP46A1 | ENSG00000036530.9 | 42702 | -3.599 | 0.0097 | No |
