Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_EXTENSION_OF_TELOMERES |
| Enrichment Score (ES) | -0.6426926 |
| Normalized Enrichment Score (NES) | -1.9356928 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0028482338 |
| FWER p-Value | 0.13 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PCNA | ENSG00000132646.11 | 8869 | 0.578 | -0.1835 | No | ||
| 2 | PRIM2 | ENSG00000146143.19 | 11511 | 0.413 | -0.2288 | No | ||
| 3 | POLD3 | ENSG00000077514.9 | 14781 | 0.293 | -0.2933 | No | ||
| 4 | POLE | ENSG00000177084.17 | 16492 | 0.220 | -0.3245 | No | ||
| 5 | TERT | ENSG00000164362.20 | 20125 | 0.042 | -0.4071 | No | ||
| 6 | POLE4 | ENSG00000115350.12 | 20281 | 0.033 | -0.4095 | No | ||
| 7 | RPA1 | ENSG00000132383.12 | 23094 | -0.118 | -0.4702 | No | ||
| 8 | RPA3 | ENSG00000106399.11 | 27907 | -0.302 | -0.5701 | No | ||
| 9 | LIG1 | ENSG00000105486.14 | 29118 | -0.354 | -0.5845 | No | ||
| 10 | PRIM1 | ENSG00000198056.15 | 30787 | -0.453 | -0.6056 | No | ||
| 11 | RFC3 | ENSG00000133119.13 | 31151 | -0.472 | -0.5958 | No | ||
| 12 | NHP2 | ENSG00000145912.8 | 33172 | -0.596 | -0.6196 | Yes | ||
| 13 | RFC5 | ENSG00000111445.14 | 33522 | -0.623 | -0.6036 | Yes | ||
| 14 | POLE2 | ENSG00000100479.13 | 34764 | -0.721 | -0.6045 | Yes | ||
| 15 | POLD4 | ENSG00000175482.9 | 35331 | -0.771 | -0.5878 | Yes | ||
| 16 | RFC1 | ENSG00000035928.16 | 36076 | -0.852 | -0.5720 | Yes | ||
| 17 | RFC2 | ENSG00000049541.11 | 36206 | -0.868 | -0.5414 | Yes | ||
| 18 | RUVBL1 | ENSG00000175792.12 | 36627 | -0.919 | -0.5156 | Yes | ||
| 19 | WRAP53 | ENSG00000141499.16 | 37477 | -1.030 | -0.4954 | Yes | ||
| 20 | RPA2 | ENSG00000117748.10 | 37640 | -1.058 | -0.4582 | Yes | ||
| 21 | RFC4 | ENSG00000163918.10 | 37809 | -1.085 | -0.4201 | Yes | ||
| 22 | FEN1 | ENSG00000168496.4 | 38431 | -1.194 | -0.3883 | Yes | ||
| 23 | DNA2 | ENSG00000138346.15 | 38510 | -1.209 | -0.3433 | Yes | ||
| 24 | DKC1 | ENSG00000130826.18 | 39123 | -1.336 | -0.3058 | Yes | ||
| 25 | POLE3 | ENSG00000148229.13 | 39649 | -1.454 | -0.2617 | Yes | ||
| 26 | POLD1 | ENSG00000062822.14 | 39718 | -1.471 | -0.2063 | Yes | ||
| 27 | RUVBL2 | ENSG00000183207.14 | 39894 | -1.521 | -0.1515 | Yes | ||
| 28 | POLD2 | ENSG00000106628.10 | 40288 | -1.623 | -0.0977 | Yes | ||
| 29 | POLA2 | ENSG00000014138.9 | 41096 | -1.906 | -0.0427 | Yes | ||
| 30 | POLA1 | ENSG00000101868.11 | 41785 | -2.314 | 0.0310 | Yes |
