Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC |
| Enrichment Score (ES) | -0.7627469 |
| Normalized Enrichment Score (NES) | -2.1802716 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.2769833E-4 |
| FWER p-Value | 0.002 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TUBA3D | ENSG00000075886.11 | 4260 | 1.082 | -0.0681 | No | ||
| 2 | CCT6B | ENSG00000132141.14 | 4283 | 1.079 | -0.0379 | No | ||
| 3 | TUBA3E | ENSG00000152086.9 | 19116 | 0.094 | -0.3794 | No | ||
| 4 | TUBA4B | ENSG00000243910.8 | 20489 | 0.024 | -0.4106 | No | ||
| 5 | TUBB1 | ENSG00000101162.3 | 20635 | 0.015 | -0.4135 | No | ||
| 6 | TUBA3C | ENSG00000198033.12 | 25534 | -0.229 | -0.5206 | No | ||
| 7 | TUBA8 | ENSG00000183785.15 | 28485 | -0.335 | -0.5795 | No | ||
| 8 | TUBB3 | ENSG00000258947.7 | 30130 | -0.416 | -0.6059 | No | ||
| 9 | TUBB4A | ENSG00000104833.12 | 30148 | -0.417 | -0.5944 | No | ||
| 10 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.7337 | Yes | ||
| 11 | TUBA1B | ENSG00000123416.15 | 37968 | -1.112 | -0.7151 | Yes | ||
| 12 | TUBB2A | ENSG00000137267.6 | 38477 | -1.201 | -0.6927 | Yes | ||
| 13 | TUBB2B | ENSG00000137285.10 | 38935 | -1.296 | -0.6664 | Yes | ||
| 14 | CCT4 | ENSG00000115484.15 | 39465 | -1.414 | -0.6385 | Yes | ||
| 15 | TCP1 | ENSG00000120438.12 | 39803 | -1.494 | -0.6038 | Yes | ||
| 16 | TUBB4B | ENSG00000188229.6 | 40254 | -1.615 | -0.5683 | Yes | ||
| 17 | CCT3 | ENSG00000163468.15 | 40427 | -1.663 | -0.5249 | Yes | ||
| 18 | CCT5 | ENSG00000150753.12 | 40604 | -1.719 | -0.4801 | Yes | ||
| 19 | CCT6A | ENSG00000146731.11 | 41295 | -2.003 | -0.4391 | Yes | ||
| 20 | CCT8 | ENSG00000156261.13 | 41377 | -2.049 | -0.3827 | Yes | ||
| 21 | CCT7 | ENSG00000135624.16 | 41607 | -2.199 | -0.3255 | Yes | ||
| 22 | TUBA1C | ENSG00000167553.15 | 41915 | -2.420 | -0.2638 | Yes | ||
| 23 | CCT2 | ENSG00000166226.13 | 42456 | -3.068 | -0.1890 | Yes | ||
| 24 | TUBA1A | ENSG00000167552.14 | 42574 | -3.253 | -0.0991 | Yes | ||
| 25 | TUBB6 | ENSG00000176014.13 | 42804 | -3.928 | 0.0073 | Yes |
