Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_GLYOXYLATE_METABOLISM_AND_GLYCINE_DEGRADATION |
| Enrichment Score (ES) | -0.6549486 |
| Normalized Enrichment Score (NES) | -1.9757838 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0014913484 |
| FWER p-Value | 0.062 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LIPT2 | ENSG00000175536.7 | 3264 | 1.275 | -0.0402 | No | ||
| 2 | GNMT | ENSG00000124713.6 | 5314 | 0.925 | -0.0620 | No | ||
| 3 | AMT | ENSG00000145020.15 | 5713 | 0.875 | -0.0468 | No | ||
| 4 | DLST | ENSG00000119689.15 | 6991 | 0.739 | -0.0558 | No | ||
| 5 | LIPT1 | ENSG00000144182.17 | 9077 | 0.566 | -0.0885 | No | ||
| 6 | HOGA1 | ENSG00000241935.9 | 11512 | 0.413 | -0.1334 | No | ||
| 7 | BCKDHB | ENSG00000083123.15 | 16615 | 0.213 | -0.2459 | No | ||
| 8 | AGXT2 | ENSG00000113492.14 | 18371 | 0.129 | -0.2830 | No | ||
| 9 | PDHA2 | ENSG00000163114.6 | 18676 | 0.114 | -0.2869 | No | ||
| 10 | PXMP2 | ENSG00000176894.10 | 22252 | -0.071 | -0.3679 | No | ||
| 11 | LIAS | ENSG00000121897.15 | 31346 | -0.482 | -0.5655 | No | ||
| 12 | GCSH | ENSG00000140905.10 | 34682 | -0.716 | -0.6229 | No | ||
| 13 | HAO1 | ENSG00000101323.5 | 35737 | -0.812 | -0.6247 | No | ||
| 14 | DHTKD1 | ENSG00000181192.12 | 37041 | -0.973 | -0.6278 | Yes | ||
| 15 | PDHX | ENSG00000110435.12 | 37146 | -0.986 | -0.6028 | Yes | ||
| 16 | DLAT | ENSG00000150768.15 | 37363 | -1.015 | -0.5795 | Yes | ||
| 17 | GLDC | ENSG00000178445.9 | 37681 | -1.063 | -0.5572 | Yes | ||
| 18 | GRHPR | ENSG00000137106.18 | 37896 | -1.100 | -0.5315 | Yes | ||
| 19 | GOT2 | ENSG00000125166.13 | 38450 | -1.197 | -0.5109 | Yes | ||
| 20 | BCKDHA | ENSG00000248098.12 | 38800 | -1.267 | -0.4837 | Yes | ||
| 21 | DBT | ENSG00000137992.14 | 38918 | -1.293 | -0.4504 | Yes | ||
| 22 | DLD | ENSG00000091140.14 | 39495 | -1.421 | -0.4241 | Yes | ||
| 23 | PDHB | ENSG00000168291.13 | 40487 | -1.684 | -0.4002 | Yes | ||
| 24 | DAO | ENSG00000110887.8 | 40654 | -1.735 | -0.3556 | Yes | ||
| 25 | OGDH | ENSG00000105953.15 | 40859 | -1.805 | -0.3100 | Yes | ||
| 26 | PDHA1 | ENSG00000131828.14 | 41112 | -1.913 | -0.2626 | Yes | ||
| 27 | AGXT | ENSG00000172482.5 | 41374 | -2.047 | -0.2115 | Yes | ||
| 28 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.1563 | Yes | ||
| 29 | ALDH4A1 | ENSG00000159423.17 | 42010 | -2.497 | -0.0941 | Yes | ||
| 30 | DDO | ENSG00000203797.10 | 42904 | -4.298 | 0.0050 | Yes |
