Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_HIV_LIFE_CYCLE |
| Enrichment Score (ES) | -0.5093457 |
| Normalized Enrichment Score (NES) | -1.9941047 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011868742 |
| FWER p-Value | 0.045 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | VPS37D | ENSG00000176428.6 | 473 | 2.643 | 0.0118 | No | ||
| 2 | HMGA1 | ENSG00000137309.19 | 1346 | 1.908 | 0.0079 | No | ||
| 3 | NUP50 | ENSG00000093000.19 | 4550 | 1.036 | -0.0577 | No | ||
| 4 | VPS4B | ENSG00000119541.10 | 4653 | 1.022 | -0.0512 | No | ||
| 5 | NUP54 | ENSG00000138750.15 | 6566 | 0.781 | -0.0890 | No | ||
| 6 | POLR2K | ENSG00000147669.11 | 6681 | 0.769 | -0.0850 | No | ||
| 7 | MVB12A | ENSG00000141971.13 | 6696 | 0.768 | -0.0787 | No | ||
| 8 | CHMP3 | ENSG00000115561.16 | 6860 | 0.751 | -0.0760 | No | ||
| 9 | GTF2H1 | ENSG00000110768.12 | 7513 | 0.689 | -0.0853 | No | ||
| 10 | ELL | ENSG00000105656.13 | 7887 | 0.656 | -0.0883 | No | ||
| 11 | MVB12B | ENSG00000196814.15 | 8016 | 0.646 | -0.0857 | No | ||
| 12 | PSIP1 | ENSG00000164985.15 | 8464 | 0.608 | -0.0909 | No | ||
| 13 | UBA52 | ENSG00000221983.8 | 9987 | 0.512 | -0.1219 | No | ||
| 14 | CDK9 | ENSG00000136807.14 | 10090 | 0.504 | -0.1199 | No | ||
| 15 | CHMP4C | ENSG00000164695.5 | 10466 | 0.481 | -0.1245 | No | ||
| 16 | CHMP4A | ENSG00000254505.10 | 10496 | 0.479 | -0.1210 | No | ||
| 17 | POLR2H | ENSG00000163882.9 | 12205 | 0.377 | -0.1575 | No | ||
| 18 | GTF2H5 | ENSG00000272047.2 | 12391 | 0.370 | -0.1586 | No | ||
| 19 | TCEA1 | ENSG00000187735.14 | 13164 | 0.348 | -0.1736 | No | ||
| 20 | PPIA | ENSG00000196262.14 | 13437 | 0.331 | -0.1771 | No | ||
| 21 | NELFCD | ENSG00000101158.15 | 14542 | 0.308 | -0.2001 | No | ||
| 22 | NELFB | ENSG00000188986.7 | 14578 | 0.305 | -0.1983 | No | ||
| 23 | ELOB | ENSG00000103363.14 | 15889 | 0.254 | -0.2266 | No | ||
| 24 | NMT1 | ENSG00000136448.12 | 16003 | 0.249 | -0.2271 | No | ||
| 25 | POLR2L | ENSG00000177700.6 | 16473 | 0.221 | -0.2361 | No | ||
| 26 | POLR2E | ENSG00000099817.12 | 16742 | 0.208 | -0.2405 | No | ||
| 27 | SUPT4H1 | ENSG00000213246.7 | 17067 | 0.194 | -0.2464 | No | ||
| 28 | UBB | ENSG00000170315.14 | 17176 | 0.189 | -0.2473 | No | ||
| 29 | GTF2B | ENSG00000137947.12 | 17284 | 0.184 | -0.2482 | No | ||
| 30 | GTF2E2 | ENSG00000197265.9 | 17377 | 0.179 | -0.2488 | No | ||
| 31 | VPS4A | ENSG00000132612.16 | 17436 | 0.176 | -0.2486 | No | ||
| 32 | TAF6 | ENSG00000106290.15 | 18064 | 0.143 | -0.2619 | No | ||
| 33 | TAF12 | ENSG00000120656.11 | 18500 | 0.125 | -0.2710 | No | ||
| 34 | GTF2H4 | ENSG00000213780.11 | 18625 | 0.117 | -0.2729 | No | ||
| 35 | CTDP1 | ENSG00000060069.16 | 18647 | 0.116 | -0.2724 | No | ||
| 36 | RCC1 | ENSG00000180198.16 | 20305 | 0.031 | -0.3106 | No | ||
| 37 | NELFA | ENSG00000185049.16 | 20702 | 0.012 | -0.3198 | No | ||
| 38 | CHMP2A | ENSG00000130724.9 | 20816 | 0.006 | -0.3223 | No | ||
| 39 | VPS28 | ENSG00000160948.14 | 20843 | 0.005 | -0.3229 | No | ||
| 40 | TAF5 | ENSG00000148835.11 | 20883 | 0.003 | -0.3238 | No | ||
| 41 | CDK7 | ENSG00000134058.12 | 21543 | -0.034 | -0.3388 | No | ||
| 42 | ELOA2 | ENSG00000206181.5 | 21573 | -0.036 | -0.3392 | No | ||
| 43 | SEC13 | ENSG00000157020.18 | 21577 | -0.036 | -0.3389 | No | ||
| 44 | CCNK | ENSG00000090061.17 | 21883 | -0.050 | -0.3456 | No | ||
| 45 | UBC | ENSG00000150991.15 | 21944 | -0.054 | -0.3465 | No | ||
| 46 | CHMP2B | ENSG00000083937.9 | 22106 | -0.063 | -0.3497 | No | ||
| 47 | CD4 | ENSG00000010610.10 | 22265 | -0.072 | -0.3528 | No | ||
| 48 | PDCD6IP | ENSG00000170248.15 | 22499 | -0.084 | -0.3575 | No | ||
| 49 | CCNH | ENSG00000134480.15 | 22740 | -0.098 | -0.3622 | No | ||
| 50 | TBP | ENSG00000112592.14 | 22837 | -0.104 | -0.3636 | No | ||
| 51 | VPS37A | ENSG00000155975.10 | 23002 | -0.112 | -0.3664 | No | ||
| 52 | NMT2 | ENSG00000152465.18 | 23501 | -0.141 | -0.3768 | No | ||
| 53 | TAF4 | ENSG00000130699.18 | 23572 | -0.145 | -0.3772 | No | ||
| 54 | POLR2J | ENSG00000005075.15 | 23836 | -0.160 | -0.3819 | No | ||
| 55 | GTF2A1 | ENSG00000165417.12 | 24077 | -0.176 | -0.3860 | No | ||
| 56 | RPS27A | ENSG00000143947.13 | 24249 | -0.185 | -0.3884 | No | ||
| 57 | TAF1 | ENSG00000147133.15 | 24787 | -0.218 | -0.3990 | No | ||
| 58 | NUP98 | ENSG00000110713.17 | 24843 | -0.220 | -0.3984 | No | ||
| 59 | TAF7L | ENSG00000102387.15 | 25549 | -0.230 | -0.4128 | No | ||
| 60 | POLR2C | ENSG00000102978.13 | 25751 | -0.243 | -0.4154 | No | ||
| 61 | RNMT | ENSG00000101654.17 | 25839 | -0.250 | -0.4152 | No | ||
| 62 | GTF2H2 | ENSG00000145736.14 | 25992 | -0.260 | -0.4165 | No | ||
| 63 | POLR2I | ENSG00000105258.9 | 26035 | -0.262 | -0.4153 | No | ||
| 64 | AAAS | ENSG00000094914.14 | 26543 | -0.269 | -0.4247 | No | ||
| 65 | POLR2F | ENSG00000100142.15 | 27064 | -0.278 | -0.4344 | No | ||
| 66 | TPR | ENSG00000047410.14 | 27549 | -0.301 | -0.4431 | No | ||
| 67 | ERCC3 | ENSG00000163161.13 | 28052 | -0.314 | -0.4521 | No | ||
| 68 | TAF10 | ENSG00000166337.10 | 28088 | -0.316 | -0.4502 | No | ||
| 69 | CHMP6 | ENSG00000176108.9 | 28428 | -0.333 | -0.4552 | No | ||
| 70 | LIG1 | ENSG00000105486.14 | 29118 | -0.354 | -0.4682 | No | ||
| 71 | POM121C | ENSG00000272391.6 | 30109 | -0.414 | -0.4876 | No | ||
| 72 | TAF4B | ENSG00000141384.12 | 30726 | -0.448 | -0.4981 | No | ||
| 73 | GTF2F1 | ENSG00000125651.14 | 30762 | -0.451 | -0.4950 | No | ||
| 74 | RAE1 | ENSG00000101146.13 | 30841 | -0.456 | -0.4929 | No | ||
| 75 | POM121 | ENSG00000196313.11 | 31048 | -0.463 | -0.4937 | No | ||
| 76 | TAF1L | ENSG00000122728.6 | 31097 | -0.467 | -0.4908 | No | ||
| 77 | UBAP1 | ENSG00000165006.14 | 31108 | -0.468 | -0.4870 | No | ||
| 78 | VPS37C | ENSG00000167987.11 | 31117 | -0.469 | -0.4831 | No | ||
| 79 | NUP37 | ENSG00000075188.9 | 31852 | -0.505 | -0.4959 | No | ||
| 80 | CHMP7 | ENSG00000147457.14 | 32432 | -0.541 | -0.5047 | Yes | ||
| 81 | CHMP4B | ENSG00000101421.4 | 32454 | -0.542 | -0.5005 | Yes | ||
| 82 | NUP133 | ENSG00000069248.12 | 32517 | -0.544 | -0.4973 | Yes | ||
| 83 | NUP205 | ENSG00000155561.15 | 32543 | -0.546 | -0.4931 | Yes | ||
| 84 | RANBP1 | ENSG00000099901.17 | 32652 | -0.556 | -0.4908 | Yes | ||
| 85 | SUPT16H | ENSG00000092201.10 | 32713 | -0.561 | -0.4874 | Yes | ||
| 86 | NELFE | ENSG00000204356.14 | 32806 | -0.569 | -0.4846 | Yes | ||
| 87 | SSRP1 | ENSG00000149136.9 | 33026 | -0.585 | -0.4847 | Yes | ||
| 88 | NUP85 | ENSG00000125450.11 | 33137 | -0.593 | -0.4821 | Yes | ||
| 89 | RANGAP1 | ENSG00000100401.19 | 33269 | -0.602 | -0.4800 | Yes | ||
| 90 | TAF2 | ENSG00000064313.12 | 33423 | -0.615 | -0.4782 | Yes | ||
| 91 | TAF9 | ENSG00000273841.5 | 33655 | -0.635 | -0.4781 | Yes | ||
| 92 | SEH1L | ENSG00000085415.16 | 33694 | -0.638 | -0.4735 | Yes | ||
| 93 | CXCR4 | ENSG00000121966.6 | 34272 | -0.681 | -0.4811 | Yes | ||
| 94 | NUP35 | ENSG00000163002.13 | 34581 | -0.709 | -0.4822 | Yes | ||
| 95 | NUP62 | ENSG00000213024.11 | 35039 | -0.744 | -0.4864 | Yes | ||
| 96 | CHMP5 | ENSG00000086065.14 | 35071 | -0.748 | -0.4806 | Yes | ||
| 97 | TAF3 | ENSG00000165632.8 | 35310 | -0.769 | -0.4795 | Yes | ||
| 98 | GTF2H3 | ENSG00000111358.14 | 35650 | -0.804 | -0.4805 | Yes | ||
| 99 | NUP43 | ENSG00000120253.14 | 35668 | -0.806 | -0.4740 | Yes | ||
| 100 | NUP214 | ENSG00000126883.17 | 35916 | -0.833 | -0.4725 | Yes | ||
| 101 | NUP160 | ENSG00000030066.13 | 35953 | -0.838 | -0.4661 | Yes | ||
| 102 | NCBP2 | ENSG00000114503.11 | 36040 | -0.848 | -0.4608 | Yes | ||
| 103 | BANF1 | ENSG00000175334.8 | 36126 | -0.859 | -0.4554 | Yes | ||
| 104 | NUP153 | ENSG00000124789.11 | 36546 | -0.906 | -0.4573 | Yes | ||
| 105 | NUP188 | ENSG00000095319.14 | 36744 | -0.935 | -0.4539 | Yes | ||
| 106 | XRCC6 | ENSG00000196419.12 | 36832 | -0.946 | -0.4477 | Yes | ||
| 107 | CCNT1 | ENSG00000129315.11 | 36877 | -0.950 | -0.4406 | Yes | ||
| 108 | KPNA1 | ENSG00000114030.13 | 36942 | -0.958 | -0.4338 | Yes | ||
| 109 | CCNT2 | ENSG00000082258.13 | 37271 | -1.002 | -0.4328 | Yes | ||
| 110 | FURIN | ENSG00000140564.12 | 37563 | -1.044 | -0.4305 | Yes | ||
| 111 | NUP107 | ENSG00000111581.10 | 37710 | -1.069 | -0.4247 | Yes | ||
| 112 | XPO1 | ENSG00000082898.17 | 37727 | -1.072 | -0.4159 | Yes | ||
| 113 | POLR2G | ENSG00000168002.12 | 37749 | -1.077 | -0.4071 | Yes | ||
| 114 | GTF2A2 | ENSG00000140307.11 | 37772 | -1.079 | -0.3983 | Yes | ||
| 115 | ELOA | ENSG00000011007.12 | 37965 | -1.112 | -0.3932 | Yes | ||
| 116 | SUPT5H | ENSG00000196235.14 | 38036 | -1.123 | -0.3851 | Yes | ||
| 117 | FEN1 | ENSG00000168496.4 | 38431 | -1.194 | -0.3840 | Yes | ||
| 118 | TSG101 | ENSG00000074319.13 | 38589 | -1.221 | -0.3771 | Yes | ||
| 119 | TAF7 | ENSG00000178913.8 | 38592 | -1.222 | -0.3666 | Yes | ||
| 120 | LIG4 | ENSG00000174405.13 | 39026 | -1.316 | -0.3653 | Yes | ||
| 121 | ELOC | ENSG00000154582.16 | 39129 | -1.337 | -0.3562 | Yes | ||
| 122 | POLR2B | ENSG00000047315.16 | 39275 | -1.369 | -0.3478 | Yes | ||
| 123 | TAF15 | ENSG00000270647.6 | 39488 | -1.420 | -0.3404 | Yes | ||
| 124 | NUP88 | ENSG00000108559.12 | 39539 | -1.429 | -0.3293 | Yes | ||
| 125 | NDC1 | ENSG00000058804.12 | 39702 | -1.467 | -0.3204 | Yes | ||
| 126 | TAF9B | ENSG00000187325.5 | 39739 | -1.475 | -0.3085 | Yes | ||
| 127 | RANBP2 | ENSG00000153201.16 | 39878 | -1.517 | -0.2987 | Yes | ||
| 128 | RAN | ENSG00000132341.12 | 39982 | -1.544 | -0.2877 | Yes | ||
| 129 | GTF2F2 | ENSG00000188342.12 | 40005 | -1.549 | -0.2749 | Yes | ||
| 130 | POLR2A | ENSG00000181222.16 | 40044 | -1.559 | -0.2623 | Yes | ||
| 131 | TAF13 | ENSG00000197780.10 | 40119 | -1.578 | -0.2505 | Yes | ||
| 132 | NUP210 | ENSG00000132182.12 | 40138 | -1.584 | -0.2372 | Yes | ||
| 133 | XRCC5 | ENSG00000079246.16 | 40327 | -1.635 | -0.2275 | Yes | ||
| 134 | POLR2D | ENSG00000144231.11 | 40398 | -1.657 | -0.2148 | Yes | ||
| 135 | NUP155 | ENSG00000113569.16 | 40500 | -1.687 | -0.2026 | Yes | ||
| 136 | RNGTT | ENSG00000111880.16 | 40533 | -1.697 | -0.1888 | Yes | ||
| 137 | VTA1 | ENSG00000009844.16 | 40695 | -1.747 | -0.1774 | Yes | ||
| 138 | GTF2E1 | ENSG00000153767.10 | 40925 | -1.833 | -0.1670 | Yes | ||
| 139 | CCR5 | ENSG00000160791.13 | 41133 | -1.925 | -0.1552 | Yes | ||
| 140 | TAF11 | ENSG00000064995.18 | 41303 | -2.008 | -0.1418 | Yes | ||
| 141 | NCBP1 | ENSG00000136937.13 | 41449 | -2.100 | -0.1271 | Yes | ||
| 142 | MNAT1 | ENSG00000020426.11 | 41558 | -2.168 | -0.1109 | Yes | ||
| 143 | ERCC2 | ENSG00000104884.15 | 41619 | -2.203 | -0.0933 | Yes | ||
| 144 | VPS37B | ENSG00000139722.7 | 41722 | -2.271 | -0.0761 | Yes | ||
| 145 | NUP58 | ENSG00000139496.16 | 41803 | -2.330 | -0.0579 | Yes | ||
| 146 | NEDD4L | ENSG00000049759.18 | 42475 | -3.096 | -0.0468 | Yes | ||
| 147 | NUP93 | ENSG00000102900.13 | 42500 | -3.124 | -0.0204 | Yes | ||
| 148 | XRCC4 | ENSG00000152422.15 | 42833 | -4.034 | 0.0067 | Yes |
