Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT |
| Enrichment Score (ES) | 0.5769019 |
| Normalized Enrichment Score (NES) | 1.8721826 |
| Nominal p-value | 0.0025188916 |
| FDR q-value | 0.02047267 |
| FWER p-Value | 0.413 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | C1S | ENSG00000182326.15 | 34 | 4.267 | 0.1483 | Yes | ||
| 2 | MASP1 | ENSG00000127241.16 | 191 | 3.323 | 0.2608 | Yes | ||
| 3 | CFB | ENSG00000243649.8 | 196 | 3.306 | 0.3762 | Yes | ||
| 4 | C1R | ENSG00000159403.18 | 251 | 3.121 | 0.4840 | Yes | ||
| 5 | CFD | ENSG00000197766.8 | 1895 | 1.671 | 0.5042 | Yes | ||
| 6 | FCN3 | ENSG00000142748.12 | 2884 | 1.360 | 0.5288 | Yes | ||
| 7 | MASP2 | ENSG00000009724.17 | 3469 | 1.231 | 0.5583 | Yes | ||
| 8 | C3 | ENSG00000125730.17 | 4292 | 1.078 | 0.5769 | Yes | ||
| 9 | FCN1 | ENSG00000085265.11 | 8484 | 0.608 | 0.5009 | No | ||
| 10 | COLEC10 | ENSG00000184374.3 | 8818 | 0.582 | 0.5135 | No | ||
| 11 | C4A | ENSG00000244731.8 | 8939 | 0.572 | 0.5307 | No | ||
| 12 | COLEC11 | ENSG00000118004.17 | 10366 | 0.487 | 0.5146 | No | ||
| 13 | C2 | ENSG00000166278.15 | 10689 | 0.466 | 0.5234 | No | ||
| 14 | MBL2 | ENSG00000165471.6 | 13582 | 0.322 | 0.4676 | No | ||
| 15 | CRP | ENSG00000132693.12 | 14159 | 0.308 | 0.4650 | No | ||
| 16 | IGLV1-51 | ENSG00000211644.3 | 18272 | 0.132 | 0.3741 | No | ||
| 17 | IGLV3-1 | ENSG00000211673.2 | 20202 | 0.037 | 0.3307 | No | ||
| 18 | CFP | ENSG00000126759.13 | 21023 | -0.005 | 0.3118 | No | ||
| 19 | C4B | ENSG00000224389.9 | 23628 | -0.148 | 0.2566 | No | ||
| 20 | IGHG2 | ENSG00000211893.4 | 24912 | -0.223 | 0.2346 | No | ||
| 21 | IGHG1 | ENSG00000211896.7 | 26070 | -0.263 | 0.2169 | No | ||
| 22 | IGHV3-7 | ENSG00000211938.2 | 27473 | -0.297 | 0.1947 | No | ||
| 23 | C1QA | ENSG00000173372.17 | 28844 | -0.351 | 0.1752 | No | ||
| 24 | IGLV7-43 | ENSG00000211652.2 | 29019 | -0.351 | 0.1835 | No | ||
| 25 | GZMM | ENSG00000197540.8 | 29690 | -0.386 | 0.1814 | No | ||
| 26 | IGLC3 | ENSG00000211679.2 | 31713 | -0.498 | 0.1519 | No | ||
| 27 | FCN2 | ENSG00000160339.16 | 32052 | -0.518 | 0.1622 | No | ||
| 28 | IGLV1-40 | ENSG00000211653.2 | 34383 | -0.691 | 0.1322 | No | ||
| 29 | IGLV1-44 | ENSG00000211651.3 | 34889 | -0.732 | 0.1461 | No | ||
| 30 | IGLC2 | ENSG00000211677.2 | 38878 | -1.284 | 0.0984 | No |
