Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING |
| Enrichment Score (ES) | 0.6258165 |
| Normalized Enrichment Score (NES) | 2.3758328 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HLA-E | ENSG00000204592.9 | 401 | 2.753 | 0.0294 | Yes | ||
| 2 | IFIT2 | ENSG00000119922.10 | 471 | 2.644 | 0.0650 | Yes | ||
| 3 | IFI35 | ENSG00000068079.7 | 607 | 2.461 | 0.0965 | Yes | ||
| 4 | IFITM2 | ENSG00000185201.16 | 775 | 2.288 | 0.1249 | Yes | ||
| 5 | IFITM3 | ENSG00000142089.16 | 861 | 2.207 | 0.1539 | Yes | ||
| 6 | IFITM1 | ENSG00000185885.16 | 887 | 2.182 | 0.1841 | Yes | ||
| 7 | HLA-B | ENSG00000234745.11 | 962 | 2.126 | 0.2123 | Yes | ||
| 8 | PSMB8 | ENSG00000204264.11 | 1023 | 2.095 | 0.2404 | Yes | ||
| 9 | STAT2 | ENSG00000170581.14 | 1323 | 1.925 | 0.2605 | Yes | ||
| 10 | STAT1 | ENSG00000115415.18 | 1379 | 1.893 | 0.2859 | Yes | ||
| 11 | IFNAR1 | ENSG00000142166.13 | 1384 | 1.890 | 0.3124 | Yes | ||
| 12 | IRF2 | ENSG00000168310.11 | 1700 | 1.754 | 0.3298 | Yes | ||
| 13 | SAMHD1 | ENSG00000101347.9 | 1794 | 1.720 | 0.3518 | Yes | ||
| 14 | MX2 | ENSG00000183486.13 | 1946 | 1.652 | 0.3716 | Yes | ||
| 15 | IFNA8 | ENSG00000120242.4 | 2046 | 1.614 | 0.3920 | Yes | ||
| 16 | IFIT3 | ENSG00000119917.14 | 2102 | 1.598 | 0.4132 | Yes | ||
| 17 | IRF3 | ENSG00000126456.16 | 2525 | 1.465 | 0.4240 | Yes | ||
| 18 | ADAR | ENSG00000160710.17 | 2750 | 1.394 | 0.4384 | Yes | ||
| 19 | OAS2 | ENSG00000111335.12 | 2849 | 1.367 | 0.4554 | Yes | ||
| 20 | IFIT1 | ENSG00000185745.10 | 2918 | 1.351 | 0.4728 | Yes | ||
| 21 | HLA-C | ENSG00000204525.16 | 2999 | 1.333 | 0.4897 | Yes | ||
| 22 | ISG20 | ENSG00000172183.15 | 3169 | 1.296 | 0.5040 | Yes | ||
| 23 | IRF9 | ENSG00000213928.9 | 3253 | 1.277 | 0.5201 | Yes | ||
| 24 | HLA-G | ENSG00000204632.11 | 3266 | 1.274 | 0.5377 | Yes | ||
| 25 | IRF1 | ENSG00000125347.14 | 3458 | 1.235 | 0.5507 | Yes | ||
| 26 | RSAD2 | ENSG00000134321.12 | 4081 | 1.115 | 0.5519 | Yes | ||
| 27 | IFI6 | ENSG00000126709.15 | 4101 | 1.111 | 0.5671 | Yes | ||
| 28 | MX1 | ENSG00000157601.14 | 4253 | 1.082 | 0.5789 | Yes | ||
| 29 | XAF1 | ENSG00000132530.17 | 4303 | 1.076 | 0.5929 | Yes | ||
| 30 | ISG15 | ENSG00000187608.10 | 4739 | 1.008 | 0.5970 | Yes | ||
| 31 | OAS3 | ENSG00000111331.13 | 4756 | 1.006 | 0.6107 | Yes | ||
| 32 | IFI27 | ENSG00000165949.12 | 5347 | 0.921 | 0.6100 | Yes | ||
| 33 | HLA-F | ENSG00000204642.14 | 5664 | 0.881 | 0.6150 | Yes | ||
| 34 | SOCS1 | ENSG00000185338.5 | 5891 | 0.854 | 0.6218 | Yes | ||
| 35 | EGR1 | ENSG00000120738.8 | 6348 | 0.802 | 0.6225 | Yes | ||
| 36 | IP6K2 | ENSG00000068745.15 | 6674 | 0.770 | 0.6258 | Yes | ||
| 37 | OASL | ENSG00000135114.12 | 7140 | 0.724 | 0.6252 | No | ||
| 38 | IRF4 | ENSG00000137265.15 | 9062 | 0.567 | 0.5886 | No | ||
| 39 | HLA-H | ENSG00000206341.7 | 10270 | 0.493 | 0.5675 | No | ||
| 40 | HLA-A | ENSG00000206503.13 | 10612 | 0.470 | 0.5662 | No | ||
| 41 | IFNA5 | ENSG00000147873.5 | 11333 | 0.425 | 0.5554 | No | ||
| 42 | IRF7 | ENSG00000185507.21 | 14110 | 0.311 | 0.4953 | No | ||
| 43 | IFNA16 | ENSG00000147885.4 | 14206 | 0.308 | 0.4975 | No | ||
| 44 | AC004551.1 | ENSG00000257452.1 | 14760 | 0.294 | 0.4888 | No | ||
| 45 | BST2 | ENSG00000130303.13 | 15884 | 0.255 | 0.4663 | No | ||
| 46 | RNASEL | ENSG00000135828.11 | 18968 | 0.100 | 0.3961 | No | ||
| 47 | JAK1 | ENSG00000162434.13 | 19624 | 0.065 | 0.3818 | No | ||
| 48 | IFNA21 | ENSG00000137080.4 | 20391 | 0.026 | 0.3644 | No | ||
| 49 | IFNAR2 | ENSG00000159110.19 | 20837 | 0.005 | 0.3541 | No | ||
| 50 | IFNA1 | ENSG00000197919.6 | 24376 | -0.192 | 0.2746 | No | ||
| 51 | IRF5 | ENSG00000128604.20 | 27146 | -0.284 | 0.2143 | No | ||
| 52 | IRF8 | ENSG00000140968.11 | 28903 | -0.351 | 0.1785 | No | ||
| 53 | TYK2 | ENSG00000105397.14 | 32192 | -0.526 | 0.1095 | No | ||
| 54 | IFNB1 | ENSG00000171855.7 | 32496 | -0.542 | 0.1101 | No | ||
| 55 | IRF6 | ENSG00000117595.12 | 33101 | -0.590 | 0.1044 | No | ||
| 56 | SOCS3 | ENSG00000184557.4 | 34239 | -0.677 | 0.0875 | No | ||
| 57 | PTPN11 | ENSG00000179295.17 | 37966 | -1.112 | 0.0166 | No | ||
| 58 | PTPN6 | ENSG00000111679.17 | 38407 | -1.189 | 0.0232 | No | ||
| 59 | GBP2 | ENSG00000162645.13 | 39071 | -1.325 | 0.0264 | No | ||
| 60 | PTPN1 | ENSG00000196396.10 | 40036 | -1.557 | 0.0259 | No | ||
| 61 | ABCE1 | ENSG00000164163.11 | 40196 | -1.598 | 0.0447 | No | ||
| 62 | USP18 | ENSG00000184979.10 | 40364 | -1.644 | 0.0640 | No |
