Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_ION_HOMEOSTASIS |
| Enrichment Score (ES) | -0.6848757 |
| Normalized Enrichment Score (NES) | -2.2780144 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.0797414E-4 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CLIC2 | ENSG00000155962.13 | 4 | 4.773 | 0.0471 | No | ||
| 2 | ASPH | ENSG00000198363.18 | 590 | 2.483 | 0.0580 | No | ||
| 3 | ATP2B4 | ENSG00000058668.14 | 627 | 2.432 | 0.0812 | No | ||
| 4 | ORAI2 | ENSG00000160991.16 | 1886 | 1.673 | 0.0685 | No | ||
| 5 | TRPC1 | ENSG00000144935.15 | 5774 | 0.867 | -0.0132 | No | ||
| 6 | SRI | ENSG00000075142.13 | 6706 | 0.767 | -0.0272 | No | ||
| 7 | FXYD7 | ENSG00000221946.7 | 8301 | 0.620 | -0.0581 | No | ||
| 8 | AHCYL1 | ENSG00000168710.18 | 12224 | 0.376 | -0.1455 | No | ||
| 9 | ORAI1 | ENSG00000276045.3 | 15880 | 0.255 | -0.2278 | No | ||
| 10 | ATP1B2 | ENSG00000129244.9 | 16230 | 0.234 | -0.2336 | No | ||
| 11 | ABCC9 | ENSG00000069431.11 | 17517 | 0.171 | -0.2618 | No | ||
| 12 | ITPR3 | ENSG00000096433.11 | 18641 | 0.116 | -0.2867 | No | ||
| 13 | ATP1A3 | ENSG00000105409.19 | 20648 | 0.014 | -0.3332 | No | ||
| 14 | ATP2A3 | ENSG00000074370.18 | 22034 | -0.059 | -0.3647 | No | ||
| 15 | FKBP1B | ENSG00000119782.14 | 22563 | -0.088 | -0.3761 | No | ||
| 16 | RYR2 | ENSG00000198626.17 | 28784 | -0.351 | -0.5171 | No | ||
| 17 | CAMK2D | ENSG00000145349.17 | 30036 | -0.410 | -0.5421 | No | ||
| 18 | FXYD2 | ENSG00000137731.14 | 30992 | -0.458 | -0.5597 | No | ||
| 19 | SLC8A2 | ENSG00000118160.14 | 33723 | -0.639 | -0.6168 | No | ||
| 20 | CAMK2G | ENSG00000148660.20 | 34193 | -0.675 | -0.6210 | No | ||
| 21 | STIM1 | ENSG00000167323.11 | 34747 | -0.720 | -0.6268 | No | ||
| 22 | FXYD3 | ENSG00000089356.18 | 34904 | -0.733 | -0.6231 | No | ||
| 23 | NOS1 | ENSG00000089250.19 | 35284 | -0.766 | -0.6244 | No | ||
| 24 | ATP1B3 | ENSG00000069849.11 | 37044 | -0.973 | -0.6556 | No | ||
| 25 | PRKACA | ENSG00000072062.14 | 37389 | -1.018 | -0.6535 | No | ||
| 26 | ATP2B3 | ENSG00000067842.17 | 38460 | -1.199 | -0.6665 | No | ||
| 27 | TRDN | ENSG00000186439.14 | 39054 | -1.322 | -0.6673 | No | ||
| 28 | FXYD4 | ENSG00000150201.15 | 39814 | -1.497 | -0.6701 | Yes | ||
| 29 | CAMK2B | ENSG00000058404.20 | 40117 | -1.578 | -0.6615 | Yes | ||
| 30 | FXYD1 | ENSG00000266964.5 | 40154 | -1.588 | -0.6467 | Yes | ||
| 31 | ATP2B2 | ENSG00000157087.20 | 40162 | -1.590 | -0.6311 | Yes | ||
| 32 | ATP2B1 | ENSG00000070961.15 | 40174 | -1.593 | -0.6156 | Yes | ||
| 33 | PLN | ENSG00000198523.6 | 40873 | -1.812 | -0.6139 | Yes | ||
| 34 | ITPR1 | ENSG00000150995.19 | 41025 | -1.877 | -0.5989 | Yes | ||
| 35 | TNNI3 | ENSG00000129991.13 | 41255 | -1.980 | -0.5847 | Yes | ||
| 36 | ATP1A1 | ENSG00000163399.16 | 41345 | -2.032 | -0.5667 | Yes | ||
| 37 | FXYD6 | ENSG00000137726.17 | 41634 | -2.212 | -0.5515 | Yes | ||
| 38 | ATP2A1 | ENSG00000196296.13 | 41742 | -2.285 | -0.5314 | Yes | ||
| 39 | ITPR2 | ENSG00000123104.12 | 41853 | -2.368 | -0.5106 | Yes | ||
| 40 | SLC8A1 | ENSG00000183023.18 | 41918 | -2.421 | -0.4882 | Yes | ||
| 41 | RYR3 | ENSG00000198838.13 | 41998 | -2.488 | -0.4654 | Yes | ||
| 42 | CASQ1 | ENSG00000143318.13 | 42074 | -2.550 | -0.4420 | Yes | ||
| 43 | ATP2A2 | ENSG00000174437.17 | 42170 | -2.663 | -0.4179 | Yes | ||
| 44 | CALM1 | ENSG00000198668.12 | 42323 | -2.877 | -0.3930 | Yes | ||
| 45 | ATP1A4 | ENSG00000132681.16 | 42353 | -2.919 | -0.3648 | Yes | ||
| 46 | ATP1B1 | ENSG00000143153.13 | 42642 | -3.447 | -0.3374 | Yes | ||
| 47 | CAMK2A | ENSG00000070808.16 | 42777 | -3.811 | -0.3029 | Yes | ||
| 48 | DMPK | ENSG00000104936.17 | 42797 | -3.886 | -0.2650 | Yes | ||
| 49 | CASQ2 | ENSG00000118729.11 | 42823 | -4.006 | -0.2260 | Yes | ||
| 50 | SLN | ENSG00000170290.4 | 42839 | -4.058 | -0.1862 | Yes | ||
| 51 | SLC8A3 | ENSG00000100678.18 | 43023 | -4.807 | -0.1430 | Yes | ||
| 52 | KCNJ11 | ENSG00000187486.5 | 43027 | -4.829 | -0.0954 | Yes | ||
| 53 | ATP1A2 | ENSG00000018625.15 | 43067 | -4.924 | -0.0476 | Yes | ||
| 54 | RYR1 | ENSG00000196218.12 | 43074 | -4.942 | 0.0010 | Yes |
