Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_METABOLISM_OF_NON_CODING_RNA |
| Enrichment Score (ES) | -0.6045052 |
| Normalized Enrichment Score (NES) | -2.0011857 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011738883 |
| FWER p-Value | 0.04 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NUP50 | ENSG00000093000.19 | 4550 | 1.036 | -0.0843 | No | ||
| 2 | NUP54 | ENSG00000138750.15 | 6566 | 0.781 | -0.1149 | No | ||
| 3 | PHAX | ENSG00000164902.14 | 10750 | 0.461 | -0.2025 | No | ||
| 4 | SNRPD2 | ENSG00000125743.10 | 13341 | 0.337 | -0.2557 | No | ||
| 5 | SNUPN | ENSG00000169371.14 | 13529 | 0.325 | -0.2533 | No | ||
| 6 | CLNS1A | ENSG00000074201.9 | 16063 | 0.245 | -0.3071 | No | ||
| 7 | GEMIN4 | ENSG00000179409.11 | 17129 | 0.191 | -0.3278 | No | ||
| 8 | TGS1 | ENSG00000137574.11 | 20524 | 0.021 | -0.4062 | No | ||
| 9 | SNRPG | ENSG00000143977.14 | 20606 | 0.017 | -0.4078 | No | ||
| 10 | GEMIN8 | ENSG00000046647.13 | 20737 | 0.010 | -0.4106 | No | ||
| 11 | SEC13 | ENSG00000157020.18 | 21577 | -0.036 | -0.4293 | No | ||
| 12 | NUP98 | ENSG00000110713.17 | 24843 | -0.220 | -0.5006 | No | ||
| 13 | AAAS | ENSG00000094914.14 | 26543 | -0.269 | -0.5345 | No | ||
| 14 | TPR | ENSG00000047410.14 | 27549 | -0.301 | -0.5516 | No | ||
| 15 | GEMIN7 | ENSG00000142252.11 | 28329 | -0.331 | -0.5628 | No | ||
| 16 | SNRPE | ENSG00000182004.13 | 29725 | -0.388 | -0.5872 | No | ||
| 17 | POM121C | ENSG00000272391.6 | 30109 | -0.414 | -0.5875 | No | ||
| 18 | RAE1 | ENSG00000101146.13 | 30841 | -0.456 | -0.5951 | Yes | ||
| 19 | GEMIN6 | ENSG00000152147.11 | 30898 | -0.457 | -0.5869 | Yes | ||
| 20 | POM121 | ENSG00000196313.11 | 31048 | -0.463 | -0.5808 | Yes | ||
| 21 | NUP37 | ENSG00000075188.9 | 31852 | -0.505 | -0.5890 | Yes | ||
| 22 | NUP133 | ENSG00000069248.12 | 32517 | -0.544 | -0.5932 | Yes | ||
| 23 | NUP205 | ENSG00000155561.15 | 32543 | -0.546 | -0.5825 | Yes | ||
| 24 | NUP85 | ENSG00000125450.11 | 33137 | -0.593 | -0.5840 | Yes | ||
| 25 | SMN2 | ENSG00000205571.13 | 33495 | -0.621 | -0.5795 | Yes | ||
| 26 | SEH1L | ENSG00000085415.16 | 33694 | -0.638 | -0.5709 | Yes | ||
| 27 | NUP35 | ENSG00000163002.13 | 34581 | -0.709 | -0.5768 | Yes | ||
| 28 | NUP62 | ENSG00000213024.11 | 35039 | -0.744 | -0.5721 | Yes | ||
| 29 | SNRPD1 | ENSG00000167088.11 | 35042 | -0.745 | -0.5567 | Yes | ||
| 30 | NUP43 | ENSG00000120253.14 | 35668 | -0.806 | -0.5546 | Yes | ||
| 31 | SNRPB | ENSG00000125835.18 | 35755 | -0.814 | -0.5398 | Yes | ||
| 32 | NUP214 | ENSG00000126883.17 | 35916 | -0.833 | -0.5263 | Yes | ||
| 33 | NUP160 | ENSG00000030066.13 | 35953 | -0.838 | -0.5098 | Yes | ||
| 34 | NCBP2 | ENSG00000114503.11 | 36040 | -0.848 | -0.4943 | Yes | ||
| 35 | NUP153 | ENSG00000124789.11 | 36546 | -0.906 | -0.4873 | Yes | ||
| 36 | NUP188 | ENSG00000095319.14 | 36744 | -0.935 | -0.4726 | Yes | ||
| 37 | SNRPF | ENSG00000139343.10 | 36890 | -0.952 | -0.4563 | Yes | ||
| 38 | NUP107 | ENSG00000111581.10 | 37710 | -1.069 | -0.4532 | Yes | ||
| 39 | DDX20 | ENSG00000064703.12 | 38326 | -1.176 | -0.4432 | Yes | ||
| 40 | SNRPD3 | ENSG00000100028.12 | 38472 | -1.201 | -0.4218 | Yes | ||
| 41 | NUP88 | ENSG00000108559.12 | 39539 | -1.429 | -0.4170 | Yes | ||
| 42 | NDC1 | ENSG00000058804.12 | 39702 | -1.467 | -0.3904 | Yes | ||
| 43 | SMN1 | ENSG00000172062.16 | 39848 | -1.506 | -0.3627 | Yes | ||
| 44 | GEMIN5 | ENSG00000082516.9 | 39872 | -1.514 | -0.3320 | Yes | ||
| 45 | RANBP2 | ENSG00000153201.16 | 39878 | -1.517 | -0.3007 | Yes | ||
| 46 | NUP210 | ENSG00000132182.12 | 40138 | -1.584 | -0.2740 | Yes | ||
| 47 | NUP155 | ENSG00000113569.16 | 40500 | -1.687 | -0.2476 | Yes | ||
| 48 | GEMIN2 | ENSG00000092208.17 | 41417 | -2.079 | -0.2259 | Yes | ||
| 49 | NCBP1 | ENSG00000136937.13 | 41449 | -2.100 | -0.1832 | Yes | ||
| 50 | NUP58 | ENSG00000139496.16 | 41803 | -2.330 | -0.1433 | Yes | ||
| 51 | PRMT5 | ENSG00000100462.16 | 41891 | -2.396 | -0.0958 | Yes | ||
| 52 | WDR77 | ENSG00000116455.14 | 42336 | -2.892 | -0.0464 | Yes | ||
| 53 | NUP93 | ENSG00000102900.13 | 42500 | -3.124 | 0.0144 | Yes |
