Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_METABOLISM_OF_STEROID_HORMONES |
| Enrichment Score (ES) | 0.5724797 |
| Normalized Enrichment Score (NES) | 1.8673474 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.020119684 |
| FWER p-Value | 0.442 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HSD17B14 | ENSG00000087076.9 | 272 | 3.059 | 0.1029 | Yes | ||
| 2 | CYP11A1 | ENSG00000140459.18 | 920 | 2.156 | 0.1650 | Yes | ||
| 3 | STAR | ENSG00000147465.12 | 1357 | 1.903 | 0.2228 | Yes | ||
| 4 | FDXR | ENSG00000161513.12 | 1927 | 1.658 | 0.2688 | Yes | ||
| 5 | HSD17B11 | ENSG00000198189.11 | 2389 | 1.508 | 0.3120 | Yes | ||
| 6 | TSPO | ENSG00000100300.18 | 2475 | 1.481 | 0.3629 | Yes | ||
| 7 | STARD4 | ENSG00000164211.13 | 3550 | 1.216 | 0.3814 | Yes | ||
| 8 | HSD3B2 | ENSG00000203859.10 | 3594 | 1.207 | 0.4235 | Yes | ||
| 9 | CYP19A1 | ENSG00000137869.15 | 4946 | 0.977 | 0.4270 | Yes | ||
| 10 | HSD11B1 | ENSG00000117594.10 | 5743 | 0.870 | 0.4397 | Yes | ||
| 11 | FDX1 | ENSG00000137714.3 | 5937 | 0.849 | 0.4655 | Yes | ||
| 12 | STARD6 | ENSG00000174448.8 | 6112 | 0.828 | 0.4910 | Yes | ||
| 13 | SRD5A3 | ENSG00000128039.11 | 6114 | 0.828 | 0.5206 | Yes | ||
| 14 | TSPOAP1 | ENSG00000005379.17 | 6121 | 0.827 | 0.5499 | Yes | ||
| 15 | SRD5A1 | ENSG00000145545.12 | 7045 | 0.733 | 0.5547 | Yes | ||
| 16 | HSD17B1 | ENSG00000108786.10 | 7364 | 0.704 | 0.5725 | Yes | ||
| 17 | HSD11B2 | ENSG00000176387.7 | 9508 | 0.537 | 0.5419 | No | ||
| 18 | FDX2 | ENSG00000267673.6 | 10225 | 0.495 | 0.5430 | No | ||
| 19 | HSD17B12 | ENSG00000149084.13 | 11318 | 0.426 | 0.5329 | No | ||
| 20 | CYP21A2 | ENSG00000231852.9 | 13927 | 0.321 | 0.4838 | No | ||
| 21 | AKR1B1 | ENSG00000085662.14 | 14091 | 0.312 | 0.4912 | No | ||
| 22 | HSD17B2 | ENSG00000086696.11 | 17842 | 0.155 | 0.4097 | No | ||
| 23 | STARD3 | ENSG00000131748.16 | 17944 | 0.149 | 0.4126 | No | ||
| 24 | POMC | ENSG00000115138.11 | 18442 | 0.128 | 0.4057 | No | ||
| 25 | CYP17A1 | ENSG00000148795.7 | 20505 | 0.022 | 0.3586 | No | ||
| 26 | CGA | ENSG00000135346.8 | 35164 | -0.757 | 0.0455 | No | ||
| 27 | AKR1B15 | ENSG00000227471.9 | 35436 | -0.782 | 0.0671 | No | ||
| 28 | SRD5A2 | ENSG00000277893.2 | 37000 | -0.965 | 0.0653 | No | ||
| 29 | LHB | ENSG00000104826.14 | 37320 | -1.009 | 0.0940 | No | ||
| 30 | STARD3NL | ENSG00000010270.13 | 38109 | -1.136 | 0.1163 | No |
