Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_MITOTIC_G2_G2_M_PHASES |
| Enrichment Score (ES) | -0.5035954 |
| Normalized Enrichment Score (NES) | -2.0304117 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.682927E-4 |
| FWER p-Value | 0.026 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB9 | ENSG00000240065.8 | 653 | 2.409 | -0.0018 | No | ||
| 2 | PSMB8 | ENSG00000204264.11 | 1023 | 2.095 | 0.0013 | No | ||
| 3 | HAUS7 | ENSG00000213397.10 | 1172 | 2.004 | 0.0090 | No | ||
| 4 | FBXL7 | ENSG00000183580.10 | 1432 | 1.874 | 0.0134 | No | ||
| 5 | TUBG2 | ENSG00000037042.9 | 1480 | 1.853 | 0.0226 | No | ||
| 6 | PRKAR2B | ENSG00000005249.13 | 2294 | 1.537 | 0.0122 | No | ||
| 7 | MZT2A | ENSG00000173272.16 | 2558 | 1.454 | 0.0141 | No | ||
| 8 | NDE1 | ENSG00000072864.15 | 3021 | 1.329 | 0.0108 | No | ||
| 9 | PSMB10 | ENSG00000205220.12 | 3086 | 1.313 | 0.0166 | No | ||
| 10 | WEE1 | ENSG00000166483.11 | 3367 | 1.252 | 0.0170 | No | ||
| 11 | TUBA3D | ENSG00000075886.11 | 4260 | 1.082 | 0.0023 | No | ||
| 12 | MZT2B | ENSG00000152082.14 | 4582 | 1.031 | 0.0005 | No | ||
| 13 | OPTN | ENSG00000123240.17 | 4961 | 0.974 | -0.0029 | No | ||
| 14 | HAUS4 | ENSG00000092036.18 | 5671 | 0.880 | -0.0145 | No | ||
| 15 | SDCCAG8 | ENSG00000054282.16 | 5716 | 0.874 | -0.0106 | No | ||
| 16 | NINL | ENSG00000101004.15 | 5761 | 0.868 | -0.0068 | No | ||
| 17 | FKBPL | ENSG00000204315.4 | 6405 | 0.797 | -0.0174 | No | ||
| 18 | LIN54 | ENSG00000189308.11 | 6699 | 0.767 | -0.0199 | No | ||
| 19 | CDK11A | ENSG00000008128.23 | 7264 | 0.713 | -0.0291 | No | ||
| 20 | PHLDA1 | ENSG00000139289.13 | 7327 | 0.707 | -0.0266 | No | ||
| 21 | CETN2 | ENSG00000147400.9 | 8628 | 0.597 | -0.0536 | No | ||
| 22 | LIN52 | ENSG00000205659.10 | 9384 | 0.545 | -0.0681 | No | ||
| 23 | FGFR1OP | ENSG00000213066.13 | 9562 | 0.533 | -0.0693 | No | ||
| 24 | UBA52 | ENSG00000221983.8 | 9987 | 0.512 | -0.0763 | No | ||
| 25 | SFI1 | ENSG00000198089.16 | 10009 | 0.511 | -0.0740 | No | ||
| 26 | HAUS2 | ENSG00000137814.11 | 10553 | 0.474 | -0.0840 | No | ||
| 27 | TP53 | ENSG00000141510.17 | 10940 | 0.449 | -0.0905 | No | ||
| 28 | RAB8A | ENSG00000167461.12 | 11021 | 0.443 | -0.0899 | No | ||
| 29 | CEP135 | ENSG00000174799.11 | 11376 | 0.422 | -0.0958 | No | ||
| 30 | HAUS1 | ENSG00000152240.13 | 13419 | 0.332 | -0.1415 | No | ||
| 31 | CEP164 | ENSG00000110274.16 | 14777 | 0.293 | -0.1715 | No | ||
| 32 | PSMA2 | ENSG00000106588.11 | 16418 | 0.224 | -0.2085 | No | ||
| 33 | TUBGCP3 | ENSG00000126216.15 | 16727 | 0.209 | -0.2145 | No | ||
| 34 | UBB | ENSG00000170315.14 | 17176 | 0.189 | -0.2239 | No | ||
| 35 | CNTRL | ENSG00000119397.16 | 17364 | 0.180 | -0.2272 | No | ||
| 36 | FOXM1 | ENSG00000111206.12 | 17426 | 0.176 | -0.2276 | No | ||
| 37 | DCTN3 | ENSG00000137100.16 | 17641 | 0.167 | -0.2317 | No | ||
| 38 | PSME1 | ENSG00000092010.15 | 17744 | 0.161 | -0.2332 | No | ||
| 39 | CEP192 | ENSG00000101639.18 | 17859 | 0.154 | -0.2350 | No | ||
| 40 | CEP57 | ENSG00000166037.11 | 18603 | 0.119 | -0.2516 | No | ||
| 41 | TUBA3E | ENSG00000152086.9 | 19116 | 0.094 | -0.2630 | No | ||
| 42 | EP300 | ENSG00000100393.13 | 19169 | 0.090 | -0.2638 | No | ||
| 43 | CEP250 | ENSG00000126001.16 | 19378 | 0.078 | -0.2682 | No | ||
| 44 | TUBA4B | ENSG00000243910.8 | 20489 | 0.024 | -0.2939 | No | ||
| 45 | LCMT1 | ENSG00000205629.12 | 20541 | 0.020 | -0.2950 | No | ||
| 46 | PSMF1 | ENSG00000125818.18 | 20560 | 0.019 | -0.2953 | No | ||
| 47 | TUBB1 | ENSG00000101162.3 | 20635 | 0.015 | -0.2969 | No | ||
| 48 | TUBGCP6 | ENSG00000128159.12 | 21020 | -0.005 | -0.3059 | No | ||
| 49 | SEM1 | ENSG00000127922.9 | 21274 | -0.020 | -0.3116 | No | ||
| 50 | CDK7 | ENSG00000134058.12 | 21543 | -0.034 | -0.3177 | No | ||
| 51 | LIN37 | ENSG00000267796.8 | 21753 | -0.045 | -0.3223 | No | ||
| 52 | UBC | ENSG00000150991.15 | 21944 | -0.054 | -0.3264 | No | ||
| 53 | CEP290 | ENSG00000198707.16 | 22110 | -0.063 | -0.3299 | No | ||
| 54 | DCTN2 | ENSG00000175203.15 | 22709 | -0.097 | -0.3433 | No | ||
| 55 | CCNH | ENSG00000134480.15 | 22740 | -0.098 | -0.3435 | No | ||
| 56 | PSMD9 | ENSG00000110801.14 | 23060 | -0.115 | -0.3503 | No | ||
| 57 | NME7 | ENSG00000143156.14 | 23079 | -0.117 | -0.3500 | No | ||
| 58 | TUBGCP5 | ENSG00000275835.5 | 23530 | -0.142 | -0.3597 | No | ||
| 59 | BTRC | ENSG00000166167.18 | 23772 | -0.155 | -0.3645 | No | ||
| 60 | PSMD5 | ENSG00000095261.14 | 23841 | -0.161 | -0.3652 | No | ||
| 61 | RPS27A | ENSG00000143947.13 | 24249 | -0.185 | -0.3736 | No | ||
| 62 | ODF2 | ENSG00000136811.16 | 24827 | -0.219 | -0.3858 | No | ||
| 63 | TUBA3C | ENSG00000198033.12 | 25534 | -0.229 | -0.4010 | No | ||
| 64 | PSMA8 | ENSG00000154611.14 | 26134 | -0.263 | -0.4135 | No | ||
| 65 | CUL1 | ENSG00000055130.17 | 26496 | -0.266 | -0.4204 | No | ||
| 66 | HAUS8 | ENSG00000131351.15 | 27074 | -0.278 | -0.4323 | No | ||
| 67 | CEP131 | ENSG00000141577.14 | 27164 | -0.285 | -0.4328 | No | ||
| 68 | BORA | ENSG00000136122.17 | 27281 | -0.294 | -0.4339 | No | ||
| 69 | CEP76 | ENSG00000101624.11 | 27507 | -0.298 | -0.4375 | No | ||
| 70 | PSMB11 | ENSG00000222028.5 | 27828 | -0.302 | -0.4432 | No | ||
| 71 | CSNK1D | ENSG00000141551.14 | 28224 | -0.325 | -0.4506 | No | ||
| 72 | HAUS3 | ENSG00000214367.8 | 28238 | -0.325 | -0.4491 | No | ||
| 73 | TUBA8 | ENSG00000183785.15 | 28485 | -0.335 | -0.4530 | No | ||
| 74 | OFD1 | ENSG00000046651.15 | 28774 | -0.350 | -0.4578 | No | ||
| 75 | PSMB3 | ENSG00000277791.5 | 29269 | -0.361 | -0.4673 | No | ||
| 76 | FBXL18 | ENSG00000155034.19 | 29520 | -0.375 | -0.4710 | No | ||
| 77 | AURKA | ENSG00000087586.17 | 29575 | -0.379 | -0.4701 | No | ||
| 78 | TUBB8 | ENSG00000261456.5 | 29700 | -0.387 | -0.4709 | No | ||
| 79 | TUBGCP2 | ENSG00000130640.13 | 30039 | -0.410 | -0.4765 | No | ||
| 80 | CCNB2 | ENSG00000157456.8 | 30092 | -0.412 | -0.4754 | No | ||
| 81 | TUBB3 | ENSG00000258947.7 | 30130 | -0.416 | -0.4739 | No | ||
| 82 | TUBB4A | ENSG00000104833.12 | 30148 | -0.417 | -0.4720 | No | ||
| 83 | CDC25B | ENSG00000101224.17 | 30297 | -0.429 | -0.4731 | No | ||
| 84 | CDC25C | ENSG00000158402.20 | 30631 | -0.445 | -0.4784 | No | ||
| 85 | PSMA1 | ENSG00000129084.17 | 30662 | -0.448 | -0.4766 | No | ||
| 86 | PSME3 | ENSG00000131467.11 | 30737 | -0.449 | -0.4758 | No | ||
| 87 | CDK11B | ENSG00000248333.8 | 30806 | -0.455 | -0.4748 | No | ||
| 88 | NEK2 | ENSG00000117650.13 | 30994 | -0.459 | -0.4767 | No | ||
| 89 | CDK1 | ENSG00000170312.16 | 31062 | -0.464 | -0.4756 | No | ||
| 90 | GTSE1 | ENSG00000075218.19 | 31135 | -0.470 | -0.4747 | No | ||
| 91 | E2F3 | ENSG00000112242.15 | 31678 | -0.497 | -0.4846 | No | ||
| 92 | PPP2R1B | ENSG00000137713.16 | 31743 | -0.499 | -0.4833 | No | ||
| 93 | PSMA3 | ENSG00000100567.13 | 31911 | -0.509 | -0.4843 | No | ||
| 94 | NEDD1 | ENSG00000139350.11 | 32523 | -0.544 | -0.4955 | No | ||
| 95 | CSNK1E | ENSG00000213923.12 | 32851 | -0.572 | -0.5000 | No | ||
| 96 | PCM1 | ENSG00000078674.17 | 33008 | -0.584 | -0.5003 | Yes | ||
| 97 | HMMR | ENSG00000072571.20 | 33009 | -0.584 | -0.4971 | Yes | ||
| 98 | PSMB1 | ENSG00000008018.9 | 33034 | -0.586 | -0.4944 | Yes | ||
| 99 | CENPF | ENSG00000117724.13 | 33145 | -0.594 | -0.4937 | Yes | ||
| 100 | RBX1 | ENSG00000100387.9 | 33259 | -0.602 | -0.4929 | Yes | ||
| 101 | PSMD13 | ENSG00000185627.18 | 33437 | -0.616 | -0.4936 | Yes | ||
| 102 | PLK4 | ENSG00000142731.11 | 33445 | -0.616 | -0.4904 | Yes | ||
| 103 | PSMB4 | ENSG00000159377.11 | 33581 | -0.627 | -0.4900 | Yes | ||
| 104 | PSME2 | ENSG00000100911.16 | 33632 | -0.632 | -0.4877 | Yes | ||
| 105 | CEP63 | ENSG00000182923.17 | 33739 | -0.640 | -0.4866 | Yes | ||
| 106 | PCNT | ENSG00000160299.17 | 33778 | -0.643 | -0.4839 | Yes | ||
| 107 | PSMD10 | ENSG00000101843.19 | 33841 | -0.648 | -0.4817 | Yes | ||
| 108 | CENPJ | ENSG00000151849.15 | 34340 | -0.687 | -0.4895 | Yes | ||
| 109 | TPX2 | ENSG00000088325.16 | 34396 | -0.692 | -0.4869 | Yes | ||
| 110 | CCNA1 | ENSG00000133101.10 | 34815 | -0.726 | -0.4926 | Yes | ||
| 111 | PPP2CB | ENSG00000104695.13 | 34925 | -0.735 | -0.4911 | Yes | ||
| 112 | PLK1 | ENSG00000166851.15 | 35046 | -0.745 | -0.4897 | Yes | ||
| 113 | E2F1 | ENSG00000101412.13 | 35122 | -0.753 | -0.4873 | Yes | ||
| 114 | SSNA1 | ENSG00000176101.12 | 35198 | -0.759 | -0.4848 | Yes | ||
| 115 | HAUS5 | ENSG00000249115.9 | 35285 | -0.766 | -0.4825 | Yes | ||
| 116 | CCNB1 | ENSG00000134057.15 | 35306 | -0.769 | -0.4787 | Yes | ||
| 117 | CCNA2 | ENSG00000145386.10 | 35426 | -0.780 | -0.4772 | Yes | ||
| 118 | PSMC5 | ENSG00000087191.13 | 35455 | -0.783 | -0.4735 | Yes | ||
| 119 | PAFAH1B1 | ENSG00000007168.13 | 35553 | -0.792 | -0.4713 | Yes | ||
| 120 | PSMA7 | ENSG00000101182.15 | 35709 | -0.810 | -0.4704 | Yes | ||
| 121 | PSMB2 | ENSG00000126067.12 | 35837 | -0.822 | -0.4688 | Yes | ||
| 122 | PSMA5 | ENSG00000143106.13 | 36170 | -0.865 | -0.4717 | Yes | ||
| 123 | CKAP5 | ENSG00000175216.15 | 36214 | -0.869 | -0.4679 | Yes | ||
| 124 | PKMYT1 | ENSG00000127564.17 | 36288 | -0.876 | -0.4647 | Yes | ||
| 125 | CEP41 | ENSG00000106477.19 | 36403 | -0.889 | -0.4624 | Yes | ||
| 126 | PSMC2 | ENSG00000161057.12 | 36487 | -0.899 | -0.4594 | Yes | ||
| 127 | MYBL2 | ENSG00000101057.16 | 36500 | -0.900 | -0.4546 | Yes | ||
| 128 | PSMB7 | ENSG00000136930.13 | 36803 | -0.941 | -0.4564 | Yes | ||
| 129 | SKP1 | ENSG00000113558.18 | 36892 | -0.952 | -0.4532 | Yes | ||
| 130 | DCTN1 | ENSG00000204843.12 | 36952 | -0.960 | -0.4492 | Yes | ||
| 131 | TUBG1 | ENSG00000131462.8 | 36973 | -0.963 | -0.4443 | Yes | ||
| 132 | CEP70 | ENSG00000114107.9 | 36979 | -0.964 | -0.4391 | Yes | ||
| 133 | CDK2 | ENSG00000123374.11 | 37047 | -0.974 | -0.4352 | Yes | ||
| 134 | PSMB6 | ENSG00000142507.10 | 37064 | -0.976 | -0.4302 | Yes | ||
| 135 | FBXW11 | ENSG00000072803.17 | 37218 | -0.994 | -0.4282 | Yes | ||
| 136 | CDK5RAP2 | ENSG00000136861.18 | 37353 | -1.014 | -0.4257 | Yes | ||
| 137 | HAUS6 | ENSG00000147874.11 | 37377 | -1.017 | -0.4205 | Yes | ||
| 138 | PRKACA | ENSG00000072062.14 | 37389 | -1.018 | -0.4151 | Yes | ||
| 139 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.4098 | Yes | ||
| 140 | CDKN1A | ENSG00000124762.13 | 37465 | -1.029 | -0.4055 | Yes | ||
| 141 | XPO1 | ENSG00000082898.17 | 37727 | -1.072 | -0.4056 | Yes | ||
| 142 | ALMS1 | ENSG00000116127.18 | 37951 | -1.109 | -0.4046 | Yes | ||
| 143 | TUBA1B | ENSG00000123416.15 | 37968 | -1.112 | -0.3988 | Yes | ||
| 144 | PPP2R1A | ENSG00000105568.18 | 38173 | -1.148 | -0.3971 | Yes | ||
| 145 | CCP110 | ENSG00000103540.16 | 38174 | -1.148 | -0.3907 | Yes | ||
| 146 | PPP2R2A | ENSG00000221914.11 | 38312 | -1.174 | -0.3874 | Yes | ||
| 147 | PSMA4 | ENSG00000041357.16 | 38333 | -1.177 | -0.3813 | Yes | ||
| 148 | DYNC1I2 | ENSG00000077380.15 | 38350 | -1.179 | -0.3751 | Yes | ||
| 149 | TUBB2A | ENSG00000137267.6 | 38477 | -1.201 | -0.3714 | Yes | ||
| 150 | ACTR1A | ENSG00000138107.13 | 38561 | -1.216 | -0.3666 | Yes | ||
| 151 | PSMB5 | ENSG00000100804.19 | 38565 | -1.217 | -0.3599 | Yes | ||
| 152 | PPP1CB | ENSG00000213639.10 | 38656 | -1.234 | -0.3551 | Yes | ||
| 153 | CDC25A | ENSG00000164045.12 | 38736 | -1.251 | -0.3500 | Yes | ||
| 154 | DYNLL1 | ENSG00000088986.11 | 38766 | -1.258 | -0.3436 | Yes | ||
| 155 | PSMD7 | ENSG00000103035.11 | 38868 | -1.282 | -0.3388 | Yes | ||
| 156 | HSP90AA1 | ENSG00000080824.18 | 38879 | -1.285 | -0.3319 | Yes | ||
| 157 | PPP2CA | ENSG00000113575.10 | 38889 | -1.286 | -0.3250 | Yes | ||
| 158 | TUBB2B | ENSG00000137285.10 | 38935 | -1.296 | -0.3188 | Yes | ||
| 159 | LIN9 | ENSG00000183814.15 | 39000 | -1.310 | -0.3130 | Yes | ||
| 160 | PPP1R12A | ENSG00000058272.19 | 39043 | -1.320 | -0.3067 | Yes | ||
| 161 | CLASP1 | ENSG00000074054.18 | 39163 | -1.344 | -0.3019 | Yes | ||
| 162 | TUBB | ENSG00000196230.13 | 39313 | -1.380 | -0.2977 | Yes | ||
| 163 | PSMD6 | ENSG00000163636.10 | 39440 | -1.407 | -0.2928 | Yes | ||
| 164 | DYNC1H1 | ENSG00000197102.12 | 39457 | -1.412 | -0.2854 | Yes | ||
| 165 | CEP72 | ENSG00000112877.8 | 39576 | -1.436 | -0.2801 | Yes | ||
| 166 | PSMA6 | ENSG00000100902.11 | 39610 | -1.444 | -0.2728 | Yes | ||
| 167 | TUBGCP4 | ENSG00000137822.12 | 39636 | -1.451 | -0.2654 | Yes | ||
| 168 | PSMD3 | ENSG00000108344.15 | 39660 | -1.456 | -0.2578 | Yes | ||
| 169 | PSMD4 | ENSG00000159352.15 | 39708 | -1.468 | -0.2507 | Yes | ||
| 170 | CEP78 | ENSG00000148019.13 | 39730 | -1.474 | -0.2430 | Yes | ||
| 171 | PSMC1 | ENSG00000100764.14 | 39751 | -1.479 | -0.2352 | Yes | ||
| 172 | PSMD12 | ENSG00000197170.10 | 40160 | -1.590 | -0.2359 | Yes | ||
| 173 | TUBB4B | ENSG00000188229.6 | 40254 | -1.615 | -0.2291 | Yes | ||
| 174 | PSMD8 | ENSG00000099341.11 | 40314 | -1.631 | -0.2214 | Yes | ||
| 175 | PSMC4 | ENSG00000013275.8 | 40405 | -1.659 | -0.2142 | Yes | ||
| 176 | CEP152 | ENSG00000103995.14 | 40456 | -1.673 | -0.2061 | Yes | ||
| 177 | PSMD11 | ENSG00000108671.11 | 40619 | -1.724 | -0.2003 | Yes | ||
| 178 | PSMD14 | ENSG00000115233.12 | 40751 | -1.767 | -0.1935 | Yes | ||
| 179 | PSMC6 | ENSG00000100519.12 | 40791 | -1.783 | -0.1845 | Yes | ||
| 180 | PPME1 | ENSG00000214517.10 | 40855 | -1.804 | -0.1759 | Yes | ||
| 181 | RBBP4 | ENSG00000162521.19 | 40876 | -1.813 | -0.1663 | Yes | ||
| 182 | HSP90AB1 | ENSG00000096384.20 | 40961 | -1.848 | -0.1580 | Yes | ||
| 183 | YWHAE | ENSG00000108953.17 | 41073 | -1.896 | -0.1500 | Yes | ||
| 184 | MZT1 | ENSG00000204899.6 | 41264 | -1.982 | -0.1434 | Yes | ||
| 185 | PSMD1 | ENSG00000173692.13 | 41284 | -1.994 | -0.1327 | Yes | ||
| 186 | MAPRE1 | ENSG00000101367.9 | 41383 | -2.053 | -0.1236 | Yes | ||
| 187 | PSMC3 | ENSG00000165916.8 | 41467 | -2.112 | -0.1138 | Yes | ||
| 188 | MNAT1 | ENSG00000020426.11 | 41558 | -2.168 | -0.1038 | Yes | ||
| 189 | AJUBA | ENSG00000129474.16 | 41642 | -2.218 | -0.0934 | Yes | ||
| 190 | PSME4 | ENSG00000068878.15 | 41799 | -2.328 | -0.0841 | Yes | ||
| 191 | AKAP9 | ENSG00000127914.16 | 41818 | -2.342 | -0.0715 | Yes | ||
| 192 | PSMD2 | ENSG00000175166.17 | 41820 | -2.343 | -0.0584 | Yes | ||
| 193 | TUBA1C | ENSG00000167553.15 | 41915 | -2.420 | -0.0472 | Yes | ||
| 194 | YWHAG | ENSG00000170027.7 | 42117 | -2.593 | -0.0374 | Yes | ||
| 195 | TUBA1A | ENSG00000167552.14 | 42574 | -3.253 | -0.0299 | Yes | ||
| 196 | PPP1R12B | ENSG00000077157.22 | 42751 | -3.726 | -0.0133 | Yes | ||
| 197 | TUBB6 | ENSG00000176014.13 | 42804 | -3.928 | 0.0073 | Yes |
