| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS |
| Enrichment Score (ES) | 0.43896827 |
| Normalized Enrichment Score (NES) | 1.8026325 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.032499682 |
| FWER p-Value | 0.73 |

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CMBL | ENSG00000164237.9 | 203 | 3.287 | 0.0232 | Yes | ||
| 2 | EPHX1 | ENSG00000143819.12 | 223 | 3.237 | 0.0502 | Yes | ||
| 3 | ACSS1 | ENSG00000154930.15 | 241 | 3.164 | 0.0766 | Yes | ||
| 4 | CYP27A1 | ENSG00000135929.9 | 400 | 2.753 | 0.0963 | Yes | ||
| 5 | CYP2E1 | ENSG00000130649.10 | 447 | 2.683 | 0.1180 | Yes | ||
| 6 | AHR | ENSG00000106546.14 | 498 | 2.602 | 0.1389 | Yes | ||
| 7 | CYP26B1 | ENSG00000003137.8 | 683 | 2.377 | 0.1547 | Yes | ||
| 8 | ADH1C | ENSG00000248144.6 | 760 | 2.300 | 0.1725 | Yes | ||
| 9 | CYP51A1 | ENSG00000001630.17 | 829 | 2.232 | 0.1898 | Yes | ||
| 10 | CYP11A1 | ENSG00000140459.18 | 920 | 2.156 | 0.2060 | Yes | ||
| 11 | CYP7B1 | ENSG00000172817.4 | 995 | 2.108 | 0.2222 | Yes | ||
| 12 | ADH4 | ENSG00000198099.8 | 1310 | 1.932 | 0.2312 | Yes | ||
| 13 | RXRA | ENSG00000186350.12 | 1332 | 1.918 | 0.2470 | Yes | ||
| 14 | ACSS2 | ENSG00000131069.20 | 1499 | 1.845 | 0.2588 | Yes | ||
| 15 | CYP2A6 | ENSG00000255974.8 | 1577 | 1.812 | 0.2724 | Yes | ||
| 16 | FMO2 | ENSG00000094963.14 | 1738 | 1.741 | 0.2834 | Yes | ||
| 17 | CES3 | ENSG00000172828.13 | 1871 | 1.680 | 0.2946 | Yes | ||
| 18 | NQO2 | ENSG00000124588.20 | 1876 | 1.678 | 0.3087 | Yes | ||
| 19 | FDXR | ENSG00000161513.12 | 1927 | 1.658 | 0.3216 | Yes | ||
| 20 | ADH5 | ENSG00000197894.11 | 1943 | 1.653 | 0.3353 | Yes | ||
| 21 | PTGIS | ENSG00000124212.6 | 2119 | 1.592 | 0.3447 | Yes | ||
| 22 | PTGS1 | ENSG00000095303.17 | 2168 | 1.577 | 0.3570 | Yes | ||
| 23 | CBR3 | ENSG00000159231.6 | 2198 | 1.567 | 0.3696 | Yes | ||
| 24 | CYP4V2 | ENSG00000145476.16 | 2229 | 1.555 | 0.3821 | Yes | ||
| 25 | AHRR | ENSG00000063438.17 | 2577 | 1.448 | 0.3863 | Yes | ||
| 26 | CYP2A7 | ENSG00000198077.10 | 2767 | 1.387 | 0.3937 | Yes | ||
| 27 | ADH1A | ENSG00000187758.8 | 2986 | 1.336 | 0.3999 | Yes | ||
| 28 | CYP2U1 | ENSG00000155016.18 | 3344 | 1.256 | 0.4023 | Yes | ||
| 29 | CYP7A1 | ENSG00000167910.4 | 3605 | 1.205 | 0.4065 | Yes | ||
| 30 | NCOA2 | ENSG00000140396.13 | 3691 | 1.187 | 0.4146 | Yes | ||
| 31 | ADH1B | ENSG00000196616.14 | 4264 | 1.081 | 0.4104 | Yes | ||
| 32 | ALDH3A1 | ENSG00000108602.18 | 4556 | 1.035 | 0.4124 | Yes | ||
| 33 | MAOB | ENSG00000069535.14 | 4865 | 0.988 | 0.4137 | Yes | ||
| 34 | CYP19A1 | ENSG00000137869.15 | 4946 | 0.977 | 0.4201 | Yes | ||
| 35 | CES2 | ENSG00000172831.13 | 4955 | 0.975 | 0.4282 | Yes | ||
| 36 | CYP24A1 | ENSG00000019186.10 | 5219 | 0.937 | 0.4300 | Yes | ||
| 37 | AIP | ENSG00000110711.10 | 5807 | 0.864 | 0.4237 | Yes | ||
| 38 | FDX1 | ENSG00000137714.3 | 5937 | 0.849 | 0.4279 | Yes | ||
| 39 | ALDH2 | ENSG00000111275.13 | 6098 | 0.829 | 0.4312 | Yes | ||
| 40 | FMO1 | ENSG00000010932.17 | 6346 | 0.803 | 0.4322 | Yes | ||
| 41 | CYP3A7 | ENSG00000160870.14 | 6768 | 0.761 | 0.4289 | Yes | ||
| 42 | CYB5R3 | ENSG00000100243.21 | 7054 | 0.733 | 0.4285 | Yes | ||
| 43 | CYP1B1 | ENSG00000138061.12 | 7105 | 0.727 | 0.4335 | Yes | ||
| 44 | PAOX | ENSG00000148832.16 | 7135 | 0.724 | 0.4390 | Yes | ||
| 45 | CYP3A5 | ENSG00000106258.15 | 7555 | 0.685 | 0.4350 | No | ||
| 46 | AADAC | ENSG00000114771.14 | 8157 | 0.633 | 0.4264 | No | ||
| 47 | CYP4F12 | ENSG00000186204.15 | 8205 | 0.628 | 0.4307 | No | ||
| 48 | CYP2F1 | ENSG00000197446.9 | 8613 | 0.598 | 0.4263 | No | ||
| 49 | FDX2 | ENSG00000267673.6 | 10225 | 0.495 | 0.3930 | No | ||
| 50 | CES1 | ENSG00000198848.12 | 10401 | 0.485 | 0.3931 | No | ||
| 51 | CYP2D6 | ENSG00000100197.22 | 10497 | 0.478 | 0.3949 | No | ||
| 52 | CYP3A43 | ENSG00000021461.16 | 12045 | 0.386 | 0.3622 | No | ||
| 53 | CYP2C19 | ENSG00000165841.11 | 12110 | 0.382 | 0.3640 | No | ||
| 54 | CYP1A2 | ENSG00000140505.7 | 12281 | 0.375 | 0.3632 | No | ||
| 55 | CYP39A1 | ENSG00000146233.8 | 12375 | 0.371 | 0.3642 | No | ||
| 56 | CYP4F8 | ENSG00000186526.13 | 12882 | 0.355 | 0.3554 | No | ||
| 57 | CYP4A22 | ENSG00000162365.12 | 13803 | 0.322 | 0.3368 | No | ||
| 58 | CYP21A2 | ENSG00000231852.9 | 13927 | 0.321 | 0.3366 | No | ||
| 59 | CYP4F22 | ENSG00000171954.13 | 14399 | 0.308 | 0.3283 | No | ||
| 60 | CYP2S1 | ENSG00000167600.14 | 15734 | 0.264 | 0.2995 | No | ||
| 61 | ADH6 | ENSG00000172955.17 | 16031 | 0.247 | 0.2948 | No | ||
| 62 | CYP2C8 | ENSG00000138115.14 | 16222 | 0.235 | 0.2923 | No | ||
| 63 | CYP2C9 | ENSG00000138109.11 | 16255 | 0.232 | 0.2936 | No | ||
| 64 | ARNT | ENSG00000143437.21 | 16305 | 0.230 | 0.2944 | No | ||
| 65 | POMC | ENSG00000115138.11 | 18442 | 0.128 | 0.2458 | No | ||
| 66 | CYP4F3 | ENSG00000186529.16 | 19942 | 0.051 | 0.2114 | No | ||
| 67 | CYP2R1 | ENSG00000186104.10 | 22814 | -0.103 | 0.1455 | No | ||
| 68 | NR1H4 | ENSG00000012504.15 | 24416 | -0.194 | 0.1099 | No | ||
| 69 | CYP3A4 | ENSG00000160868.15 | 24773 | -0.217 | 0.1035 | No | ||
| 70 | ADH7 | ENSG00000196344.11 | 25515 | -0.228 | 0.0882 | No | ||
| 71 | CYP4F2 | ENSG00000186115.13 | 26235 | -0.263 | 0.0737 | No | ||
| 72 | CYP2B6 | ENSG00000197408.10 | 26275 | -0.263 | 0.0751 | No | ||
| 73 | AOC1 | ENSG00000002726.20 | 27268 | -0.293 | 0.0545 | No | ||
| 74 | FMO3 | ENSG00000007933.13 | 29589 | -0.380 | 0.0038 | No | ||
| 75 | MAOA | ENSG00000189221.9 | 29884 | -0.397 | 0.0003 | No | ||
| 76 | CYB5B | ENSG00000103018.16 | 30781 | -0.453 | -0.0167 | No | ||
| 77 | CYP1A1 | ENSG00000140465.14 | 31019 | -0.461 | -0.0183 | No | ||
| 78 | CYP2C18 | ENSG00000108242.13 | 31100 | -0.467 | -0.0162 | No | ||
| 79 | PTGES3 | ENSG00000110958.16 | 31379 | -0.484 | -0.0185 | No | ||
| 80 | MARC2 | ENSG00000117791.16 | 31737 | -0.499 | -0.0226 | No | ||
| 81 | CYP26C1 | ENSG00000187553.10 | 32196 | -0.526 | -0.0288 | No | ||
| 82 | POR | ENSG00000127948.16 | 32862 | -0.573 | -0.0394 | No | ||
| 83 | BPHL | ENSG00000137274.13 | 32864 | -0.573 | -0.0345 | No | ||
| 84 | CYP8B1 | ENSG00000180432.6 | 34531 | -0.704 | -0.0673 | No | ||
| 85 | MARC1 | ENSG00000186205.13 | 34537 | -0.705 | -0.0614 | No | ||
| 86 | CYP4F11 | ENSG00000171903.16 | 35089 | -0.750 | -0.0679 | No | ||
| 87 | CYP26A1 | ENSG00000095596.12 | 35654 | -0.804 | -0.0742 | No | ||
| 88 | CYP27B1 | ENSG00000111012.10 | 36871 | -0.950 | -0.0944 | No | ||
| 89 | TBXAS1 | ENSG00000059377.17 | 37979 | -1.115 | -0.1107 | No | ||
| 90 | AOC2 | ENSG00000131480.9 | 38802 | -1.268 | -0.1190 | No | ||
| 91 | CYP2W1 | ENSG00000073067.14 | 39272 | -1.368 | -0.1183 | No | ||
| 92 | SMOX | ENSG00000088826.18 | 39379 | -1.393 | -0.1090 | No | ||
| 93 | NCOA1 | ENSG00000084676.15 | 39735 | -1.475 | -0.1047 | No | ||
| 94 | ARNT2 | ENSG00000172379.21 | 40803 | -1.786 | -0.1144 | No | ||
| 95 | HSP90AB1 | ENSG00000096384.20 | 40961 | -1.848 | -0.1024 | No | ||
| 96 | AOC3 | ENSG00000131471.7 | 41327 | -2.021 | -0.0937 | No | ||
| 97 | CYP2J2 | ENSG00000134716.11 | 42672 | -3.507 | -0.0952 | No | ||
| 98 | CYP46A1 | ENSG00000036530.9 | 42702 | -3.599 | -0.0654 | No | ||
| 99 | ALDH1B1 | ENSG00000137124.8 | 42890 | -4.254 | -0.0336 | No | ||
| 100 | ALDH1A1 | ENSG00000165092.13 | 42972 | -4.592 | 0.0034 | No |

