Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE |
| Enrichment Score (ES) | 0.55834794 |
| Normalized Enrichment Score (NES) | 1.8589919 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02060918 |
| FWER p-Value | 0.476 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LIPA | ENSG00000107798.18 | 528 | 2.571 | 0.0598 | Yes | ||
| 2 | LDLR | ENSG00000130164.13 | 900 | 2.174 | 0.1121 | Yes | ||
| 3 | NPC2 | ENSG00000119655.10 | 904 | 2.166 | 0.1728 | Yes | ||
| 4 | CUBN | ENSG00000107611.15 | 1068 | 2.070 | 0.2270 | Yes | ||
| 5 | LIPC | ENSG00000166035.11 | 1162 | 2.011 | 0.2812 | Yes | ||
| 6 | SOAT1 | ENSG00000057252.13 | 1704 | 1.753 | 0.3178 | Yes | ||
| 7 | CES3 | ENSG00000172828.13 | 1871 | 1.680 | 0.3610 | Yes | ||
| 8 | MYLIP | ENSG00000007944.15 | 2034 | 1.618 | 0.4026 | Yes | ||
| 9 | CLTA | ENSG00000122705.17 | 2253 | 1.549 | 0.4410 | Yes | ||
| 10 | NR1H3 | ENSG00000025434.19 | 2274 | 1.542 | 0.4837 | Yes | ||
| 11 | LDLRAP1 | ENSG00000157978.11 | 3364 | 1.252 | 0.4935 | Yes | ||
| 12 | PCSK9 | ENSG00000169174.10 | 3586 | 1.208 | 0.5223 | Yes | ||
| 13 | SCARB1 | ENSG00000073060.16 | 3609 | 1.204 | 0.5555 | Yes | ||
| 14 | AP2B1 | ENSG00000006125.18 | 5163 | 0.946 | 0.5460 | Yes | ||
| 15 | AP2A2 | ENSG00000183020.13 | 6293 | 0.807 | 0.5424 | Yes | ||
| 16 | NR1H2 | ENSG00000131408.15 | 6552 | 0.783 | 0.5583 | Yes | ||
| 17 | APOBR | ENSG00000184730.11 | 10096 | 0.504 | 0.4902 | No | ||
| 18 | AP2A1 | ENSG00000196961.12 | 11282 | 0.428 | 0.4747 | No | ||
| 19 | HDLBP | ENSG00000115677.17 | 12315 | 0.374 | 0.4613 | No | ||
| 20 | APOB | ENSG00000084674.14 | 12681 | 0.362 | 0.4630 | No | ||
| 21 | CLTC | ENSG00000141367.12 | 12768 | 0.357 | 0.4710 | No | ||
| 22 | LSR | ENSG00000105699.16 | 17054 | 0.196 | 0.3770 | No | ||
| 23 | AP2S1 | ENSG00000042753.11 | 18891 | 0.104 | 0.3373 | No | ||
| 24 | NPC1 | ENSG00000141458.13 | 21917 | -0.052 | 0.2685 | No | ||
| 25 | AMN | ENSG00000166126.10 | 22776 | -0.101 | 0.2515 | No | ||
| 26 | APOC4 | ENSG00000267467.4 | 26268 | -0.263 | 0.1778 | No | ||
| 27 | AP2M1 | ENSG00000161203.13 | 28129 | -0.319 | 0.1436 | No | ||
| 28 | APOC1 | ENSG00000130208.9 | 33251 | -0.601 | 0.0416 | No | ||
| 29 | SOAT2 | ENSG00000167780.12 | 33443 | -0.616 | 0.0544 | No | ||
| 30 | APOE | ENSG00000130203.10 | 37045 | -0.973 | -0.0019 | No | ||
| 31 | NCEH1 | ENSG00000144959.10 | 38293 | -1.171 | 0.0020 | No | ||
| 32 | APOA1 | ENSG00000118137.9 | 41195 | -1.956 | -0.0105 | No | ||
| 33 | VLDLR | ENSG00000147852.16 | 41219 | -1.967 | 0.0441 | No |
