Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC |
| Enrichment Score (ES) | -0.73707724 |
| Normalized Enrichment Score (NES) | -2.1186826 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.199759E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PFDN5 | ENSG00000123349.14 | 2762 | 1.389 | -0.0304 | No | ||
| 2 | TUBA3D | ENSG00000075886.11 | 4260 | 1.082 | -0.0389 | No | ||
| 3 | CCT6B | ENSG00000132141.14 | 4283 | 1.079 | -0.0132 | No | ||
| 4 | PFDN4 | ENSG00000101132.10 | 9223 | 0.553 | -0.1144 | No | ||
| 5 | PFDN1 | ENSG00000113068.10 | 16728 | 0.209 | -0.2835 | No | ||
| 6 | TUBB1 | ENSG00000101162.3 | 20635 | 0.015 | -0.3738 | No | ||
| 7 | TUBA3C | ENSG00000198033.12 | 25534 | -0.229 | -0.4819 | No | ||
| 8 | TUBB3 | ENSG00000258947.7 | 30130 | -0.416 | -0.5784 | No | ||
| 9 | TUBB4A | ENSG00000104833.12 | 30148 | -0.417 | -0.5687 | No | ||
| 10 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.7123 | Yes | ||
| 11 | VBP1 | ENSG00000155959.12 | 38118 | -1.138 | -0.7012 | Yes | ||
| 12 | TUBB2A | ENSG00000137267.6 | 38477 | -1.201 | -0.6804 | Yes | ||
| 13 | ACTB | ENSG00000075624.16 | 38506 | -1.208 | -0.6518 | Yes | ||
| 14 | TUBB2B | ENSG00000137285.10 | 38935 | -1.296 | -0.6303 | Yes | ||
| 15 | PFDN6 | ENSG00000204220.11 | 39373 | -1.391 | -0.6067 | Yes | ||
| 16 | CCT4 | ENSG00000115484.15 | 39465 | -1.414 | -0.5745 | Yes | ||
| 17 | TCP1 | ENSG00000120438.12 | 39803 | -1.494 | -0.5460 | Yes | ||
| 18 | TUBB4B | ENSG00000188229.6 | 40254 | -1.615 | -0.5173 | Yes | ||
| 19 | CCT3 | ENSG00000163468.15 | 40427 | -1.663 | -0.4810 | Yes | ||
| 20 | CCT5 | ENSG00000150753.12 | 40604 | -1.719 | -0.4434 | Yes | ||
| 21 | PFDN2 | ENSG00000143256.5 | 40735 | -1.758 | -0.4037 | Yes | ||
| 22 | CCT6A | ENSG00000146731.11 | 41295 | -2.003 | -0.3681 | Yes | ||
| 23 | CCT8 | ENSG00000156261.13 | 41377 | -2.049 | -0.3203 | Yes | ||
| 24 | CCT7 | ENSG00000135624.16 | 41607 | -2.199 | -0.2723 | Yes | ||
| 25 | TUBA1C | ENSG00000167553.15 | 41915 | -2.420 | -0.2207 | Yes | ||
| 26 | CCT2 | ENSG00000166226.13 | 42456 | -3.068 | -0.1588 | Yes | ||
| 27 | TUBA1A | ENSG00000167552.14 | 42574 | -3.253 | -0.0827 | Yes | ||
| 28 | TUBB6 | ENSG00000176014.13 | 42804 | -3.928 | 0.0073 | Yes |
