Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_REGULATED_NECROSIS |
| Enrichment Score (ES) | 0.6171486 |
| Normalized Enrichment Score (NES) | 1.7864662 |
| Nominal p-value | 0.0074074073 |
| FDR q-value | 0.037721727 |
| FWER p-Value | 0.78 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | FAS | ENSG00000026103.22 | 911 | 2.164 | 0.1158 | Yes | ||
| 2 | RIPK3 | ENSG00000129465.16 | 1517 | 1.836 | 0.2181 | Yes | ||
| 3 | MLKL | ENSG00000168404.13 | 1838 | 1.698 | 0.3181 | Yes | ||
| 4 | TRADD | ENSG00000102871.16 | 2807 | 1.376 | 0.3828 | Yes | ||
| 5 | RIPK1 | ENSG00000137275.14 | 2864 | 1.362 | 0.4677 | Yes | ||
| 6 | TNFSF10 | ENSG00000121858.11 | 3755 | 1.173 | 0.5213 | Yes | ||
| 7 | TNFRSF10B | ENSG00000120889.13 | 3864 | 1.152 | 0.5917 | Yes | ||
| 8 | TNFRSF10A | ENSG00000104689.10 | 5298 | 0.927 | 0.6171 | Yes | ||
| 9 | CASP8 | ENSG00000064012.21 | 7888 | 0.656 | 0.5986 | No | ||
| 10 | UBA52 | ENSG00000221983.8 | 9987 | 0.512 | 0.5824 | No | ||
| 11 | CFLAR | ENSG00000003402.20 | 10310 | 0.491 | 0.6059 | No | ||
| 12 | BIRC3 | ENSG00000023445.14 | 12432 | 0.366 | 0.5799 | No | ||
| 13 | FADD | ENSG00000168040.4 | 16318 | 0.229 | 0.5043 | No | ||
| 14 | UBB | ENSG00000170315.14 | 17176 | 0.189 | 0.4964 | No | ||
| 15 | TRAF2 | ENSG00000127191.18 | 21170 | -0.015 | 0.4047 | No | ||
| 16 | UBC | ENSG00000150991.15 | 21944 | -0.054 | 0.3901 | No | ||
| 17 | RPS27A | ENSG00000143947.13 | 24249 | -0.185 | 0.3484 | No | ||
| 18 | FASLG | ENSG00000117560.8 | 28350 | -0.331 | 0.2742 | No | ||
| 19 | BIRC2 | ENSG00000110330.8 | 29123 | -0.355 | 0.2788 | No | ||
| 20 | XIAP | ENSG00000101966.12 | 34810 | -0.725 | 0.1928 | No |
