Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT |
| Enrichment Score (ES) | -0.56840533 |
| Normalized Enrichment Score (NES) | -2.107863 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.499799E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SDHD | ENSG00000204370.12 | 3584 | 1.209 | -0.0675 | No | ||
| 2 | COQ10B | ENSG00000115520.8 | 6352 | 0.802 | -0.1213 | No | ||
| 3 | NDUFA7 | ENSG00000267855.6 | 7349 | 0.706 | -0.1352 | No | ||
| 4 | UQCRB | ENSG00000156467.9 | 10109 | 0.503 | -0.1927 | No | ||
| 5 | ECSIT | ENSG00000130159.14 | 10673 | 0.467 | -0.1997 | No | ||
| 6 | TMEM126B | ENSG00000171204.12 | 10826 | 0.457 | -0.1973 | No | ||
| 7 | NDUFA13 | ENSG00000186010.19 | 11809 | 0.396 | -0.2149 | No | ||
| 8 | NDUFS4 | ENSG00000164258.12 | 15726 | 0.264 | -0.3025 | No | ||
| 9 | COX4I1 | ENSG00000131143.9 | 15881 | 0.255 | -0.3027 | No | ||
| 10 | NDUFA11 | ENSG00000174886.13 | 17272 | 0.185 | -0.3326 | No | ||
| 11 | COX18 | ENSG00000163626.16 | 18243 | 0.134 | -0.3534 | No | ||
| 12 | SURF1 | ENSG00000148290.10 | 19112 | 0.094 | -0.3723 | No | ||
| 13 | NDUFB10 | ENSG00000140990.15 | 19165 | 0.090 | -0.3723 | No | ||
| 14 | COX20 | ENSG00000203667.10 | 20597 | 0.017 | -0.4054 | No | ||
| 15 | UQCRH | ENSG00000173660.12 | 21041 | -0.006 | -0.4156 | No | ||
| 16 | NDUFA2 | ENSG00000131495.8 | 21146 | -0.013 | -0.4178 | No | ||
| 17 | COX7A2L | ENSG00000115944.15 | 21364 | -0.024 | -0.4226 | No | ||
| 18 | UQCR11 | ENSG00000127540.12 | 21789 | -0.046 | -0.4318 | No | ||
| 19 | COX16 | ENSG00000133983.16 | 21797 | -0.047 | -0.4314 | No | ||
| 20 | NDUFB1 | ENSG00000183648.10 | 22559 | -0.088 | -0.4479 | No | ||
| 21 | COX14 | ENSG00000178449.9 | 23151 | -0.121 | -0.4601 | No | ||
| 22 | COX7C | ENSG00000127184.13 | 23199 | -0.124 | -0.4595 | No | ||
| 23 | NDUFS7 | ENSG00000115286.20 | 23943 | -0.168 | -0.4746 | No | ||
| 24 | NDUFB8 | ENSG00000166136.16 | 23962 | -0.169 | -0.4728 | No | ||
| 25 | NDUFAF6 | ENSG00000156170.13 | 24099 | -0.177 | -0.4736 | No | ||
| 26 | NDUFAF3 | ENSG00000178057.15 | 24112 | -0.177 | -0.4716 | No | ||
| 27 | SDHA | ENSG00000073578.17 | 24192 | -0.182 | -0.4711 | No | ||
| 28 | NDUFC2 | ENSG00000151366.13 | 24279 | -0.187 | -0.4706 | No | ||
| 29 | NDUFAF2 | ENSG00000164182.11 | 24595 | -0.204 | -0.4752 | No | ||
| 30 | ETFB | ENSG00000105379.9 | 24745 | -0.215 | -0.4759 | No | ||
| 31 | COX6B1 | ENSG00000126267.11 | 25561 | -0.231 | -0.4918 | No | ||
| 32 | NUBPL | ENSG00000151413.17 | 25649 | -0.237 | -0.4907 | No | ||
| 33 | NDUFC1 | ENSG00000109390.12 | 26484 | -0.265 | -0.5066 | No | ||
| 34 | NDUFA5 | ENSG00000128609.15 | 27038 | -0.276 | -0.5159 | No | ||
| 35 | NDUFAF7 | ENSG00000003509.16 | 28221 | -0.325 | -0.5391 | No | ||
| 36 | NDUFAF4 | ENSG00000123545.6 | 29188 | -0.359 | -0.5568 | No | ||
| 37 | ACAD9 | ENSG00000177646.19 | 29272 | -0.361 | -0.5540 | No | ||
| 38 | COX6A1 | ENSG00000111775.3 | 29637 | -0.384 | -0.5575 | No | ||
| 39 | NDUFS3 | ENSG00000213619.10 | 30108 | -0.414 | -0.5630 | Yes | ||
| 40 | NDUFS8 | ENSG00000110717.13 | 30259 | -0.426 | -0.5609 | Yes | ||
| 41 | NDUFA6 | ENSG00000184983.11 | 30283 | -0.428 | -0.5558 | Yes | ||
| 42 | SDHC | ENSG00000143252.14 | 30372 | -0.429 | -0.5522 | Yes | ||
| 43 | NDUFA10 | ENSG00000130414.12 | 30583 | -0.440 | -0.5514 | Yes | ||
| 44 | NDUFB7 | ENSG00000099795.7 | 30995 | -0.459 | -0.5549 | Yes | ||
| 45 | NDUFV1 | ENSG00000167792.13 | 31274 | -0.476 | -0.5551 | Yes | ||
| 46 | NDUFB4 | ENSG00000065518.8 | 31830 | -0.503 | -0.5614 | Yes | ||
| 47 | NDUFAF5 | ENSG00000101247.18 | 31864 | -0.506 | -0.5556 | Yes | ||
| 48 | ETFDH | ENSG00000171503.12 | 32005 | -0.514 | -0.5521 | Yes | ||
| 49 | NDUFA1 | ENSG00000125356.7 | 32133 | -0.521 | -0.5482 | Yes | ||
| 50 | NDUFB5 | ENSG00000136521.13 | 32252 | -0.531 | -0.5440 | Yes | ||
| 51 | NDUFB11 | ENSG00000147123.10 | 32900 | -0.576 | -0.5515 | Yes | ||
| 52 | SDHB | ENSG00000117118.9 | 33081 | -0.589 | -0.5480 | Yes | ||
| 53 | MT-ND6 | ENSG00000198695.2 | 33237 | -0.601 | -0.5437 | Yes | ||
| 54 | MT-ND1 | ENSG00000198888.2 | 33602 | -0.630 | -0.5439 | Yes | ||
| 55 | NDUFV2 | ENSG00000178127.13 | 33641 | -0.633 | -0.5365 | Yes | ||
| 56 | MT-ND5 | ENSG00000198786.2 | 33909 | -0.654 | -0.5341 | Yes | ||
| 57 | NDUFB2 | ENSG00000090266.13 | 33932 | -0.656 | -0.5260 | Yes | ||
| 58 | COX5B | ENSG00000135940.7 | 33952 | -0.658 | -0.5179 | Yes | ||
| 59 | COX8A | ENSG00000176340.4 | 34436 | -0.697 | -0.5200 | Yes | ||
| 60 | MT-CO3 | ENSG00000198938.2 | 34569 | -0.708 | -0.5138 | Yes | ||
| 61 | MT-CO1 | ENSG00000198804.2 | 34603 | -0.710 | -0.5052 | Yes | ||
| 62 | NDUFA3 | ENSG00000170906.16 | 35193 | -0.759 | -0.5090 | Yes | ||
| 63 | MT-ND3 | ENSG00000198840.2 | 35569 | -0.794 | -0.5073 | Yes | ||
| 64 | TACO1 | ENSG00000136463.8 | 35845 | -0.823 | -0.5029 | Yes | ||
| 65 | MT-ND4 | ENSG00000198886.2 | 36465 | -0.896 | -0.5055 | Yes | ||
| 66 | LRPPRC | ENSG00000138095.19 | 36597 | -0.914 | -0.4966 | Yes | ||
| 67 | UQCRFS1 | ENSG00000169021.6 | 37078 | -0.978 | -0.4949 | Yes | ||
| 68 | NDUFV3 | ENSG00000160194.18 | 37212 | -0.994 | -0.4850 | Yes | ||
| 69 | TIMMDC1 | ENSG00000113845.10 | 37656 | -1.060 | -0.4814 | Yes | ||
| 70 | NDUFS6 | ENSG00000145494.11 | 37676 | -1.062 | -0.4679 | Yes | ||
| 71 | MT-ND2 | ENSG00000198763.3 | 37747 | -1.076 | -0.4555 | Yes | ||
| 72 | MT-CYB | ENSG00000198727.2 | 37765 | -1.078 | -0.4417 | Yes | ||
| 73 | UQCR10 | ENSG00000184076.13 | 37826 | -1.087 | -0.4289 | Yes | ||
| 74 | COX7B | ENSG00000131174.7 | 37903 | -1.101 | -0.4162 | Yes | ||
| 75 | NDUFA9 | ENSG00000139180.11 | 38015 | -1.119 | -0.4042 | Yes | ||
| 76 | UQCRQ | ENSG00000164405.11 | 38111 | -1.136 | -0.3915 | Yes | ||
| 77 | NDUFA12 | ENSG00000184752.13 | 38215 | -1.156 | -0.3787 | Yes | ||
| 78 | NDUFS5 | ENSG00000168653.11 | 38239 | -1.160 | -0.3641 | Yes | ||
| 79 | NDUFB6 | ENSG00000165264.11 | 38305 | -1.173 | -0.3502 | Yes | ||
| 80 | NDUFA8 | ENSG00000119421.7 | 38322 | -1.176 | -0.3352 | Yes | ||
| 81 | CYC1 | ENSG00000179091.5 | 38710 | -1.245 | -0.3278 | Yes | ||
| 82 | UQCRC1 | ENSG00000010256.11 | 38824 | -1.273 | -0.3138 | Yes | ||
| 83 | MT-CO2 | ENSG00000198712.1 | 38915 | -1.292 | -0.2990 | Yes | ||
| 84 | COX6C | ENSG00000164919.11 | 39588 | -1.439 | -0.2957 | Yes | ||
| 85 | NDUFA4 | ENSG00000189043.10 | 39683 | -1.463 | -0.2787 | Yes | ||
| 86 | NDUFB3 | ENSG00000119013.9 | 40121 | -1.579 | -0.2682 | Yes | ||
| 87 | SCO1 | ENSG00000133028.12 | 40267 | -1.617 | -0.2504 | Yes | ||
| 88 | ETFA | ENSG00000140374.16 | 40279 | -1.619 | -0.2294 | Yes | ||
| 89 | NDUFS1 | ENSG00000023228.14 | 40350 | -1.642 | -0.2096 | Yes | ||
| 90 | TRAP1 | ENSG00000126602.11 | 40422 | -1.662 | -0.1894 | Yes | ||
| 91 | NDUFAF1 | ENSG00000137806.9 | 40536 | -1.698 | -0.1698 | Yes | ||
| 92 | COX5A | ENSG00000178741.12 | 40756 | -1.769 | -0.1517 | Yes | ||
| 93 | UQCRC2 | ENSG00000140740.11 | 40862 | -1.806 | -0.1305 | Yes | ||
| 94 | NDUFB9 | ENSG00000147684.9 | 41155 | -1.935 | -0.1119 | Yes | ||
| 95 | NDUFS2 | ENSG00000158864.12 | 41582 | -2.182 | -0.0932 | Yes | ||
| 96 | COX11 | ENSG00000166260.11 | 41593 | -2.189 | -0.0648 | Yes | ||
| 97 | COQ10A | ENSG00000135469.13 | 41608 | -2.199 | -0.0363 | Yes | ||
| 98 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.0088 | Yes | ||
| 99 | CYCS | ENSG00000172115.8 | 42546 | -3.206 | 0.0133 | Yes |
