Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS |
| Enrichment Score (ES) | -0.54579896 |
| Normalized Enrichment Score (NES) | -1.9675921 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0015802073 |
| FWER p-Value | 0.069 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLR2K | ENSG00000147669.11 | 6681 | 0.769 | -0.1417 | No | ||
| 2 | GTF2H1 | ENSG00000110768.12 | 7513 | 0.689 | -0.1490 | No | ||
| 3 | ELL | ENSG00000105656.13 | 7887 | 0.656 | -0.1461 | No | ||
| 4 | CDK9 | ENSG00000136807.14 | 10090 | 0.504 | -0.1884 | No | ||
| 5 | MLLT1 | ENSG00000130382.9 | 10960 | 0.447 | -0.2008 | No | ||
| 6 | POLR2H | ENSG00000163882.9 | 12205 | 0.377 | -0.2231 | No | ||
| 7 | GTF2H5 | ENSG00000272047.2 | 12391 | 0.370 | -0.2209 | No | ||
| 8 | TCEA1 | ENSG00000187735.14 | 13164 | 0.348 | -0.2327 | No | ||
| 9 | RTF1 | ENSG00000137815.14 | 13564 | 0.323 | -0.2363 | No | ||
| 10 | NELFCD | ENSG00000101158.15 | 14542 | 0.308 | -0.2536 | No | ||
| 11 | NELFB | ENSG00000188986.7 | 14578 | 0.305 | -0.2491 | No | ||
| 12 | CTR9 | ENSG00000198730.9 | 15754 | 0.262 | -0.2718 | No | ||
| 13 | ELOB | ENSG00000103363.14 | 15889 | 0.254 | -0.2704 | No | ||
| 14 | POLR2L | ENSG00000177700.6 | 16473 | 0.221 | -0.2801 | No | ||
| 15 | POLR2E | ENSG00000099817.12 | 16742 | 0.208 | -0.2827 | No | ||
| 16 | SUPT4H1 | ENSG00000213246.7 | 17067 | 0.194 | -0.2868 | No | ||
| 17 | GTF2B | ENSG00000137947.12 | 17284 | 0.184 | -0.2886 | No | ||
| 18 | GTF2E2 | ENSG00000197265.9 | 17377 | 0.179 | -0.2876 | No | ||
| 19 | TAF6 | ENSG00000106290.15 | 18064 | 0.143 | -0.3010 | No | ||
| 20 | TAF12 | ENSG00000120656.11 | 18500 | 0.125 | -0.3089 | No | ||
| 21 | GTF2H4 | ENSG00000213780.11 | 18625 | 0.117 | -0.3098 | No | ||
| 22 | CTDP1 | ENSG00000060069.16 | 18647 | 0.116 | -0.3082 | No | ||
| 23 | NELFA | ENSG00000185049.16 | 20702 | 0.012 | -0.3557 | No | ||
| 24 | TAF5 | ENSG00000148835.11 | 20883 | 0.003 | -0.3599 | No | ||
| 25 | CDK7 | ENSG00000134058.12 | 21543 | -0.034 | -0.3746 | No | ||
| 26 | ELOA2 | ENSG00000206181.5 | 21573 | -0.036 | -0.3746 | No | ||
| 27 | CCNK | ENSG00000090061.17 | 21883 | -0.050 | -0.3809 | No | ||
| 28 | PAF1 | ENSG00000006712.15 | 22600 | -0.090 | -0.3960 | No | ||
| 29 | CCNH | ENSG00000134480.15 | 22740 | -0.098 | -0.3975 | No | ||
| 30 | TBP | ENSG00000112592.14 | 22837 | -0.104 | -0.3979 | No | ||
| 31 | TAF4 | ENSG00000130699.18 | 23572 | -0.145 | -0.4124 | No | ||
| 32 | POLR2J | ENSG00000005075.15 | 23836 | -0.160 | -0.4157 | No | ||
| 33 | GTF2A1 | ENSG00000165417.12 | 24077 | -0.176 | -0.4182 | No | ||
| 34 | TAF1 | ENSG00000147133.15 | 24787 | -0.218 | -0.4309 | No | ||
| 35 | TAF7L | ENSG00000102387.15 | 25549 | -0.230 | -0.4445 | No | ||
| 36 | POLR2C | ENSG00000102978.13 | 25751 | -0.243 | -0.4449 | No | ||
| 37 | GTF2H2 | ENSG00000145736.14 | 25992 | -0.260 | -0.4459 | No | ||
| 38 | POLR2I | ENSG00000105258.9 | 26035 | -0.262 | -0.4423 | No | ||
| 39 | POLR2F | ENSG00000100142.15 | 27064 | -0.278 | -0.4613 | No | ||
| 40 | WDR61 | ENSG00000140395.9 | 27247 | -0.291 | -0.4604 | No | ||
| 41 | ERCC3 | ENSG00000163161.13 | 28052 | -0.314 | -0.4736 | No | ||
| 42 | TAF10 | ENSG00000166337.10 | 28088 | -0.316 | -0.4689 | No | ||
| 43 | LEO1 | ENSG00000166477.13 | 29390 | -0.369 | -0.4926 | No | ||
| 44 | TAF4B | ENSG00000141384.12 | 30726 | -0.448 | -0.5158 | No | ||
| 45 | GTF2F1 | ENSG00000125651.14 | 30762 | -0.451 | -0.5087 | No | ||
| 46 | TAF1L | ENSG00000122728.6 | 31097 | -0.467 | -0.5083 | No | ||
| 47 | SUPT16H | ENSG00000092201.10 | 32713 | -0.561 | -0.5360 | Yes | ||
| 48 | NELFE | ENSG00000204356.14 | 32806 | -0.569 | -0.5281 | Yes | ||
| 49 | SSRP1 | ENSG00000149136.9 | 33026 | -0.585 | -0.5229 | Yes | ||
| 50 | TAF2 | ENSG00000064313.12 | 33423 | -0.615 | -0.5214 | Yes | ||
| 51 | TAF9 | ENSG00000273841.5 | 33655 | -0.635 | -0.5156 | Yes | ||
| 52 | SUPT6H | ENSG00000109111.15 | 34750 | -0.721 | -0.5284 | Yes | ||
| 53 | AFF4 | ENSG00000072364.13 | 35098 | -0.750 | -0.5233 | Yes | ||
| 54 | TAF3 | ENSG00000165632.8 | 35310 | -0.769 | -0.5147 | Yes | ||
| 55 | GTF2H3 | ENSG00000111358.14 | 35650 | -0.804 | -0.5085 | Yes | ||
| 56 | NCBP2 | ENSG00000114503.11 | 36040 | -0.848 | -0.5026 | Yes | ||
| 57 | CCNT1 | ENSG00000129315.11 | 36877 | -0.950 | -0.5054 | Yes | ||
| 58 | CCNT2 | ENSG00000082258.13 | 37271 | -1.002 | -0.4969 | Yes | ||
| 59 | MLLT3 | ENSG00000171843.16 | 37475 | -1.030 | -0.4836 | Yes | ||
| 60 | POLR2G | ENSG00000168002.12 | 37749 | -1.077 | -0.4711 | Yes | ||
| 61 | GTF2A2 | ENSG00000140307.11 | 37772 | -1.079 | -0.4526 | Yes | ||
| 62 | ELOA | ENSG00000011007.12 | 37965 | -1.112 | -0.4376 | Yes | ||
| 63 | SUPT5H | ENSG00000196235.14 | 38036 | -1.123 | -0.4195 | Yes | ||
| 64 | TAF7 | ENSG00000178913.8 | 38592 | -1.222 | -0.4110 | Yes | ||
| 65 | IWS1 | ENSG00000163166.15 | 38993 | -1.308 | -0.3974 | Yes | ||
| 66 | EAF1 | ENSG00000144597.14 | 39110 | -1.333 | -0.3767 | Yes | ||
| 67 | ELOC | ENSG00000154582.16 | 39129 | -1.337 | -0.3537 | Yes | ||
| 68 | POLR2B | ENSG00000047315.16 | 39275 | -1.369 | -0.3330 | Yes | ||
| 69 | TAF15 | ENSG00000270647.6 | 39488 | -1.420 | -0.3131 | Yes | ||
| 70 | CDC73 | ENSG00000134371.13 | 39684 | -1.463 | -0.2919 | Yes | ||
| 71 | TAF9B | ENSG00000187325.5 | 39739 | -1.475 | -0.2673 | Yes | ||
| 72 | GTF2F2 | ENSG00000188342.12 | 40005 | -1.549 | -0.2463 | Yes | ||
| 73 | POLR2A | ENSG00000181222.16 | 40044 | -1.559 | -0.2199 | Yes | ||
| 74 | TAF13 | ENSG00000197780.10 | 40119 | -1.578 | -0.1939 | Yes | ||
| 75 | POLR2D | ENSG00000144231.11 | 40398 | -1.657 | -0.1713 | Yes | ||
| 76 | GTF2E1 | ENSG00000153767.10 | 40925 | -1.833 | -0.1514 | Yes | ||
| 77 | TAF11 | ENSG00000064995.18 | 41303 | -2.008 | -0.1249 | Yes | ||
| 78 | NCBP1 | ENSG00000136937.13 | 41449 | -2.100 | -0.0915 | Yes | ||
| 79 | MNAT1 | ENSG00000020426.11 | 41558 | -2.168 | -0.0559 | Yes | ||
| 80 | ERCC2 | ENSG00000104884.15 | 41619 | -2.203 | -0.0187 | Yes | ||
| 81 | EAF2 | ENSG00000145088.9 | 42447 | -3.053 | 0.0156 | Yes |
