Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL |
| Enrichment Score (ES) | -0.6324502 |
| Normalized Enrichment Score (NES) | -2.1042557 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.3155992E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RPS9 | ENSG00000170889.14 | 4738 | 1.009 | -0.0912 | No | ||
| 2 | RPS14 | ENSG00000164587.13 | 5837 | 0.860 | -0.1006 | No | ||
| 3 | RPS6 | ENSG00000137154.13 | 6666 | 0.771 | -0.1055 | No | ||
| 4 | FBL | ENSG00000105202.9 | 7708 | 0.671 | -0.1171 | No | ||
| 5 | IMP3 | ENSG00000177971.8 | 9596 | 0.530 | -0.1510 | No | ||
| 6 | THUMPD1 | ENSG00000066654.14 | 16212 | 0.235 | -0.3003 | No | ||
| 7 | UTP25 | ENSG00000117597.18 | 20790 | 0.008 | -0.4064 | No | ||
| 8 | WDR46 | ENSG00000227057.10 | 22276 | -0.073 | -0.4395 | No | ||
| 9 | RPS7 | ENSG00000171863.15 | 22391 | -0.079 | -0.4407 | No | ||
| 10 | WDR36 | ENSG00000134987.11 | 22510 | -0.085 | -0.4419 | No | ||
| 11 | RPS2 | ENSG00000140988.16 | 24024 | -0.173 | -0.4738 | No | ||
| 12 | FCF1 | ENSG00000119616.11 | 24509 | -0.200 | -0.4813 | No | ||
| 13 | UTP18 | ENSG00000011260.14 | 25495 | -0.227 | -0.4999 | No | ||
| 14 | SNU13 | ENSG00000100138.15 | 25739 | -0.242 | -0.5011 | No | ||
| 15 | UTP20 | ENSG00000120800.5 | 26474 | -0.264 | -0.5132 | No | ||
| 16 | RRP7A | ENSG00000189306.11 | 27199 | -0.288 | -0.5246 | No | ||
| 17 | TRMT112 | ENSG00000173113.6 | 27220 | -0.289 | -0.5197 | No | ||
| 18 | KRR1 | ENSG00000111615.14 | 27913 | -0.303 | -0.5301 | No | ||
| 19 | PWP2 | ENSG00000241945.8 | 28126 | -0.319 | -0.5291 | No | ||
| 20 | RRP36 | ENSG00000124541.7 | 28314 | -0.330 | -0.5272 | No | ||
| 21 | DDX47 | ENSG00000213782.7 | 29197 | -0.360 | -0.5410 | No | ||
| 22 | TSR3 | ENSG00000007520.4 | 31287 | -0.477 | -0.5806 | No | ||
| 23 | NOC4L | ENSG00000184967.7 | 31861 | -0.506 | -0.5845 | No | ||
| 24 | DIMT1 | ENSG00000086189.10 | 32513 | -0.543 | -0.5894 | No | ||
| 25 | IMP4 | ENSG00000136718.9 | 32922 | -0.577 | -0.5881 | No | ||
| 26 | NOP14 | ENSG00000087269.16 | 32946 | -0.579 | -0.5779 | No | ||
| 27 | NHP2 | ENSG00000145912.8 | 33172 | -0.596 | -0.5720 | No | ||
| 28 | MPHOSPH10 | ENSG00000124383.9 | 34601 | -0.710 | -0.5919 | No | ||
| 29 | NAT10 | ENSG00000135372.9 | 36350 | -0.883 | -0.6160 | Yes | ||
| 30 | WDR43 | ENSG00000163811.12 | 36387 | -0.886 | -0.6003 | Yes | ||
| 31 | TBL3 | ENSG00000183751.15 | 36578 | -0.910 | -0.5877 | Yes | ||
| 32 | HEATR1 | ENSG00000119285.11 | 36951 | -0.960 | -0.5784 | Yes | ||
| 33 | DDX49 | ENSG00000105671.12 | 37095 | -0.979 | -0.5634 | Yes | ||
| 34 | NOL6 | ENSG00000165271.17 | 37341 | -1.012 | -0.5502 | Yes | ||
| 35 | UTP4 | ENSG00000141076.18 | 37569 | -1.045 | -0.5360 | Yes | ||
| 36 | DDX52 | ENSG00000278053.5 | 37690 | -1.065 | -0.5189 | Yes | ||
| 37 | BMS1 | ENSG00000165733.8 | 37988 | -1.116 | -0.5049 | Yes | ||
| 38 | BUD23 | ENSG00000071462.11 | 38028 | -1.122 | -0.4849 | Yes | ||
| 39 | EMG1 | ENSG00000126749.16 | 38133 | -1.141 | -0.4660 | Yes | ||
| 40 | WDR75 | ENSG00000115368.10 | 38332 | -1.177 | -0.4486 | Yes | ||
| 41 | NOP2 | ENSG00000111641.11 | 38743 | -1.252 | -0.4348 | Yes | ||
| 42 | UTP6 | ENSG00000108651.10 | 38785 | -1.262 | -0.4121 | Yes | ||
| 43 | DCAF13 | ENSG00000164934.14 | 38847 | -1.278 | -0.3897 | Yes | ||
| 44 | DKC1 | ENSG00000130826.18 | 39123 | -1.336 | -0.3711 | Yes | ||
| 45 | UTP3 | ENSG00000132467.4 | 39173 | -1.348 | -0.3471 | Yes | ||
| 46 | RCL1 | ENSG00000120158.12 | 39318 | -1.381 | -0.3247 | Yes | ||
| 47 | DHX37 | ENSG00000150990.8 | 39333 | -1.384 | -0.2991 | Yes | ||
| 48 | UTP15 | ENSG00000164338.10 | 39467 | -1.415 | -0.2758 | Yes | ||
| 49 | RRP9 | ENSG00000114767.7 | 39550 | -1.431 | -0.2510 | Yes | ||
| 50 | UTP14A | ENSG00000156697.13 | 39926 | -1.528 | -0.2311 | Yes | ||
| 51 | NOP10 | ENSG00000182117.5 | 40108 | -1.576 | -0.2059 | Yes | ||
| 52 | GAR1 | ENSG00000109534.17 | 40146 | -1.586 | -0.1772 | Yes | ||
| 53 | NOP58 | ENSG00000055044.11 | 40229 | -1.608 | -0.1490 | Yes | ||
| 54 | NOP56 | ENSG00000101361.17 | 40492 | -1.685 | -0.1237 | Yes | ||
| 55 | UTP11 | ENSG00000183520.12 | 40833 | -1.795 | -0.0980 | Yes | ||
| 56 | NOL11 | ENSG00000130935.10 | 41165 | -1.944 | -0.0694 | Yes | ||
| 57 | PDCD11 | ENSG00000148843.15 | 41221 | -1.967 | -0.0340 | Yes | ||
| 58 | PNO1 | ENSG00000115946.8 | 41309 | -2.014 | 0.0016 | Yes | ||
| 59 | WDR3 | ENSG00000065183.16 | 41551 | -2.163 | 0.0364 | Yes |
