Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS |
| Enrichment Score (ES) | 0.5418985 |
| Normalized Enrichment Score (NES) | 1.8062229 |
| Nominal p-value | 0.0025773195 |
| FDR q-value | 0.032162923 |
| FWER p-Value | 0.714 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | OSBPL1A | ENSG00000141447.18 | 144 | 3.507 | 0.0778 | Yes | ||
| 2 | ACOX2 | ENSG00000168306.13 | 370 | 2.812 | 0.1377 | Yes | ||
| 3 | CYP27A1 | ENSG00000135929.9 | 400 | 2.753 | 0.2007 | Yes | ||
| 4 | CYP7B1 | ENSG00000172817.4 | 995 | 2.108 | 0.2357 | Yes | ||
| 5 | RXRA | ENSG00000186350.12 | 1332 | 1.918 | 0.2723 | Yes | ||
| 6 | SLC27A5 | ENSG00000083807.10 | 1786 | 1.722 | 0.3017 | Yes | ||
| 7 | PTGIS | ENSG00000124212.6 | 2119 | 1.592 | 0.3308 | Yes | ||
| 8 | AKR1C1 | ENSG00000187134.14 | 2865 | 1.362 | 0.3451 | Yes | ||
| 9 | AKR1C3 | ENSG00000196139.14 | 3123 | 1.306 | 0.3693 | Yes | ||
| 10 | CH25H | ENSG00000138135.7 | 3303 | 1.268 | 0.3945 | Yes | ||
| 11 | OSBPL3 | ENSG00000070882.13 | 3598 | 1.207 | 0.4156 | Yes | ||
| 12 | CYP7A1 | ENSG00000167910.4 | 3605 | 1.205 | 0.4434 | Yes | ||
| 13 | NCOA2 | ENSG00000140396.13 | 3691 | 1.187 | 0.4689 | Yes | ||
| 14 | AKR1C4 | ENSG00000198610.11 | 3885 | 1.148 | 0.4910 | Yes | ||
| 15 | AKR1C2 | ENSG00000151632.17 | 4394 | 1.062 | 0.5037 | Yes | ||
| 16 | HSD3B7 | ENSG00000099377.14 | 4474 | 1.048 | 0.5262 | Yes | ||
| 17 | SCP2 | ENSG00000116171.18 | 4794 | 0.999 | 0.5419 | Yes | ||
| 18 | ACOT8 | ENSG00000101473.17 | 11383 | 0.422 | 0.3988 | No | ||
| 19 | CYP39A1 | ENSG00000146233.8 | 12375 | 0.371 | 0.3843 | No | ||
| 20 | OSBPL2 | ENSG00000130703.16 | 12992 | 0.355 | 0.3783 | No | ||
| 21 | ABCB11 | ENSG00000073734.10 | 19500 | 0.072 | 0.2289 | No | ||
| 22 | OSBP | ENSG00000110048.12 | 20544 | 0.019 | 0.2052 | No | ||
| 23 | HSD17B4 | ENSG00000133835.16 | 24029 | -0.173 | 0.1283 | No | ||
| 24 | NR1H4 | ENSG00000012504.15 | 24416 | -0.194 | 0.1238 | No | ||
| 25 | OSBPL9 | ENSG00000117859.19 | 27087 | -0.279 | 0.0683 | No | ||
| 26 | SLC27A2 | ENSG00000140284.11 | 30591 | -0.441 | -0.0028 | No | ||
| 27 | AMACR | ENSG00000242110.8 | 31155 | -0.472 | -0.0049 | No | ||
| 28 | CYP8B1 | ENSG00000180432.6 | 34531 | -0.704 | -0.0669 | No | ||
| 29 | AKR1D1 | ENSG00000122787.15 | 35205 | -0.760 | -0.0650 | No | ||
| 30 | NCOA1 | ENSG00000084676.15 | 39735 | -1.475 | -0.1360 | No | ||
| 31 | OSBPL6 | ENSG00000079156.17 | 42066 | -2.542 | -0.1312 | No | ||
| 32 | BAAT | ENSG00000136881.11 | 42499 | -3.123 | -0.0689 | No | ||
| 33 | CYP46A1 | ENSG00000036530.9 | 42702 | -3.599 | 0.0097 | No |
