Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION |
| Enrichment Score (ES) | 0.5822385 |
| Normalized Enrichment Score (NES) | 1.7057995 |
| Nominal p-value | 0.007142857 |
| FDR q-value | 0.06714439 |
| FWER p-Value | 0.962 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TRIM25 | ENSG00000121060.18 | 1739 | 1.741 | 0.0748 | Yes | ||
| 2 | IFIH1 | ENSG00000115267.8 | 1866 | 1.683 | 0.1832 | Yes | ||
| 3 | IFNA8 | ENSG00000120242.4 | 2046 | 1.614 | 0.2858 | Yes | ||
| 4 | IKBKE | ENSG00000263528.8 | 2500 | 1.475 | 0.3729 | Yes | ||
| 5 | IRF3 | ENSG00000126456.16 | 2525 | 1.465 | 0.4692 | Yes | ||
| 6 | RNF135 | ENSG00000181481.14 | 2699 | 1.409 | 0.5584 | Yes | ||
| 7 | DDX58 | ENSG00000107201.10 | 4602 | 1.028 | 0.5822 | Yes | ||
| 8 | CREBBP | ENSG00000005339.14 | 7714 | 0.671 | 0.5544 | No | ||
| 9 | IFNA5 | ENSG00000147873.5 | 11333 | 0.425 | 0.4986 | No | ||
| 10 | TANK | ENSG00000136560.14 | 11874 | 0.395 | 0.5122 | No | ||
| 11 | IRF7 | ENSG00000185507.21 | 14110 | 0.311 | 0.4808 | No | ||
| 12 | IFNA16 | ENSG00000147885.4 | 14206 | 0.308 | 0.4990 | No | ||
| 13 | SIKE1 | ENSG00000052723.11 | 14741 | 0.295 | 0.5061 | No | ||
| 14 | TBK1 | ENSG00000183735.10 | 14758 | 0.294 | 0.5252 | No | ||
| 15 | MAVS | ENSG00000088888.18 | 15930 | 0.253 | 0.5148 | No | ||
| 16 | EP300 | ENSG00000100393.13 | 19169 | 0.090 | 0.4456 | No | ||
| 17 | IFNA21 | ENSG00000137080.4 | 20391 | 0.026 | 0.4191 | No | ||
| 18 | TRAF2 | ENSG00000127191.18 | 21170 | -0.015 | 0.4020 | No | ||
| 19 | IFNA1 | ENSG00000197919.6 | 24376 | -0.192 | 0.3403 | No | ||
| 20 | IFNB1 | ENSG00000171855.7 | 32496 | -0.542 | 0.1878 | No | ||
| 21 | TRAF6 | ENSG00000175104.15 | 36390 | -0.887 | 0.1561 | No |
