Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | REACTOME_TRANSLOCATION_OF_SLC2A4_GLUT4_TO_THE_PLASMA_MEMBRANE |
| Enrichment Score (ES) | -0.60143524 |
| Normalized Enrichment Score (NES) | -2.118825 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.4997415E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RAB13 | ENSG00000143545.9 | 1028 | 2.092 | 0.0036 | No | ||
| 2 | RHOQ | ENSG00000119729.12 | 3643 | 1.196 | -0.0414 | No | ||
| 3 | TUBA3D | ENSG00000075886.11 | 4260 | 1.082 | -0.0415 | No | ||
| 4 | AKT2 | ENSG00000105221.18 | 4775 | 1.001 | -0.0403 | No | ||
| 5 | VAMP2 | ENSG00000220205.9 | 4784 | 1.000 | -0.0274 | No | ||
| 6 | C2CD5 | ENSG00000111731.12 | 5017 | 0.965 | -0.0201 | No | ||
| 7 | PRKAG1 | ENSG00000181929.13 | 6839 | 0.753 | -0.0525 | No | ||
| 8 | YWHAQ | ENSG00000134308.14 | 7168 | 0.722 | -0.0507 | No | ||
| 9 | STXBP3 | ENSG00000116266.11 | 7238 | 0.715 | -0.0429 | No | ||
| 10 | YWHAZ | ENSG00000164924.18 | 7777 | 0.666 | -0.0466 | No | ||
| 11 | TBC1D4 | ENSG00000136111.14 | 10452 | 0.481 | -0.1024 | No | ||
| 12 | RAB8A | ENSG00000167461.12 | 11021 | 0.443 | -0.1098 | No | ||
| 13 | KIF3B | ENSG00000101350.8 | 15502 | 0.275 | -0.2103 | No | ||
| 14 | PRKAB1 | ENSG00000111725.11 | 16157 | 0.239 | -0.2223 | No | ||
| 15 | RAB4A | ENSG00000168118.12 | 16757 | 0.208 | -0.2335 | No | ||
| 16 | RAC1 | ENSG00000136238.18 | 16886 | 0.203 | -0.2338 | No | ||
| 17 | RAB11A | ENSG00000103769.10 | 17771 | 0.159 | -0.2523 | No | ||
| 18 | YWHAB | ENSG00000166913.13 | 17880 | 0.152 | -0.2528 | No | ||
| 19 | EXOC8 | ENSG00000116903.7 | 18726 | 0.111 | -0.2710 | No | ||
| 20 | TUBA3E | ENSG00000152086.9 | 19116 | 0.094 | -0.2788 | No | ||
| 21 | RALGAPB | ENSG00000170471.15 | 19591 | 0.067 | -0.2889 | No | ||
| 22 | EXOC7 | ENSG00000182473.22 | 19633 | 0.065 | -0.2890 | No | ||
| 23 | KIFAP3 | ENSG00000075945.13 | 20234 | 0.036 | -0.3025 | No | ||
| 24 | TUBA4B | ENSG00000243910.8 | 20489 | 0.024 | -0.3080 | No | ||
| 25 | TUBB1 | ENSG00000101162.3 | 20635 | 0.015 | -0.3112 | No | ||
| 26 | ASPSCR1 | ENSG00000169696.16 | 21123 | -0.012 | -0.3224 | No | ||
| 27 | STX4 | ENSG00000103496.15 | 23081 | -0.117 | -0.3663 | No | ||
| 28 | SFN | ENSG00000175793.12 | 23845 | -0.161 | -0.3819 | No | ||
| 29 | TUBA3C | ENSG00000198033.12 | 25534 | -0.229 | -0.4181 | No | ||
| 30 | YWHAH | ENSG00000128245.15 | 25599 | -0.233 | -0.4165 | No | ||
| 31 | RAB14 | ENSG00000119396.11 | 25916 | -0.255 | -0.4205 | No | ||
| 32 | LNPEP | ENSG00000113441.16 | 26537 | -0.269 | -0.4314 | No | ||
| 33 | TUBA8 | ENSG00000183785.15 | 28485 | -0.335 | -0.4722 | No | ||
| 34 | TUBB8 | ENSG00000261456.5 | 29700 | -0.387 | -0.4953 | No | ||
| 35 | TUBB3 | ENSG00000258947.7 | 30130 | -0.416 | -0.4998 | No | ||
| 36 | TUBB4A | ENSG00000104833.12 | 30148 | -0.417 | -0.4948 | No | ||
| 37 | EXOC3 | ENSG00000180104.16 | 30423 | -0.433 | -0.4954 | No | ||
| 38 | ACTG1 | ENSG00000184009.12 | 30626 | -0.445 | -0.4943 | No | ||
| 39 | KIF3A | ENSG00000131437.15 | 31508 | -0.489 | -0.5083 | No | ||
| 40 | EXOC4 | ENSG00000131558.15 | 32395 | -0.538 | -0.5219 | No | ||
| 41 | AKT1 | ENSG00000142208.16 | 33520 | -0.623 | -0.5398 | No | ||
| 42 | EXOC5 | ENSG00000070367.16 | 33579 | -0.627 | -0.5329 | No | ||
| 43 | EXOC2 | ENSG00000112685.14 | 33913 | -0.655 | -0.5320 | No | ||
| 44 | EXOC1 | ENSG00000090989.18 | 36402 | -0.889 | -0.5782 | No | ||
| 45 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.5880 | Yes | ||
| 46 | MYO1C | ENSG00000197879.17 | 37451 | -1.026 | -0.5756 | Yes | ||
| 47 | TUBA1B | ENSG00000123416.15 | 37968 | -1.112 | -0.5730 | Yes | ||
| 48 | TUBB2A | ENSG00000137267.6 | 38477 | -1.201 | -0.5690 | Yes | ||
| 49 | ACTB | ENSG00000075624.16 | 38506 | -1.208 | -0.5538 | Yes | ||
| 50 | SNAP23 | ENSG00000092531.10 | 38725 | -1.249 | -0.5425 | Yes | ||
| 51 | TUBB2B | ENSG00000137285.10 | 38935 | -1.296 | -0.5303 | Yes | ||
| 52 | RAB10 | ENSG00000084733.11 | 39040 | -1.320 | -0.5154 | Yes | ||
| 53 | RALGAPA2 | ENSG00000188559.15 | 39628 | -1.448 | -0.5100 | Yes | ||
| 54 | RALA | ENSG00000006451.8 | 39921 | -1.528 | -0.4968 | Yes | ||
| 55 | SLC2A4 | ENSG00000181856.15 | 40178 | -1.594 | -0.4818 | Yes | ||
| 56 | TUBB4B | ENSG00000188229.6 | 40254 | -1.615 | -0.4623 | Yes | ||
| 57 | YWHAE | ENSG00000108953.17 | 41073 | -1.896 | -0.4564 | Yes | ||
| 58 | MYO5A | ENSG00000197535.14 | 41410 | -2.070 | -0.4371 | Yes | ||
| 59 | MYH9 | ENSG00000100345.21 | 41599 | -2.193 | -0.4126 | Yes | ||
| 60 | PRKAG2 | ENSG00000106617.14 | 41635 | -2.213 | -0.3844 | Yes | ||
| 61 | TUBA1C | ENSG00000167553.15 | 41915 | -2.420 | -0.3591 | Yes | ||
| 62 | PRKAA2 | ENSG00000162409.11 | 41921 | -2.424 | -0.3274 | Yes | ||
| 63 | YWHAG | ENSG00000170027.7 | 42117 | -2.593 | -0.2979 | Yes | ||
| 64 | EXOC6 | ENSG00000138190.17 | 42220 | -2.737 | -0.2643 | Yes | ||
| 65 | CALM1 | ENSG00000198668.12 | 42323 | -2.877 | -0.2289 | Yes | ||
| 66 | PRKAB2 | ENSG00000131791.8 | 42379 | -2.953 | -0.1914 | Yes | ||
| 67 | TUBA1A | ENSG00000167552.14 | 42574 | -3.253 | -0.1532 | Yes | ||
| 68 | TBC1D1 | ENSG00000065882.16 | 42789 | -3.864 | -0.1075 | Yes | ||
| 69 | TUBB6 | ENSG00000176014.13 | 42804 | -3.928 | -0.0563 | Yes | ||
| 70 | PRKAG3 | ENSG00000115592.11 | 43035 | -4.840 | 0.0020 | Yes |
