Details for gene set HALLMARK_ALLOGRAFT_REJECTION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_ALLOGRAFT_REJECTION
Enrichment Score (ES)	0.25127137
Normalized Enrichment Score (NES)	1.2034577
Nominal p-value	0.13480055
FDR q-value	0.1992838
FWER p-Value	0.996

Fig 1: Enrichment plot: HALLMARK_ALLOGRAFT_REJECTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NLRP3	ENSG00000162711.17			20	1.857	0.0267	Yes
2	TGFB2	ENSG00000092969.12			152	1.317	0.0428	Yes
3	IL13	ENSG00000169194.9			180	1.275	0.0608	Yes
4	KLRD1	ENSG00000134539.17			278	1.149	0.0752	Yes
5	TPD52	ENSG00000076554.15			340	1.096	0.0898	Yes
6	TIMP1	ENSG00000102265.12			352	1.090	0.1055	Yes
7	IRF7	ENSG00000185507.21			812	0.910	0.1076	Yes
8	ITGAL	ENSG00000005844.18			971	0.866	0.1164	Yes
9	IL16	ENSG00000172349.17			1160	0.825	0.1239	Yes
10	WAS	ENSG00000015285.10			1194	0.819	0.1351	Yes
11	IRF4	ENSG00000137265.15			1229	0.811	0.1461	Yes
12	TLR2	ENSG00000137462.8			1599	0.759	0.1482	Yes
13	LIF	ENSG00000128342.5			1603	0.758	0.1593	Yes
14	IGSF6	ENSG00000140749.9			1683	0.748	0.1683	Yes
15	CCL7	ENSG00000108688.11			1881	0.720	0.1740	Yes
16	ELANE	ENSG00000197561.7			2173	0.686	0.1770	Yes
17	IL2RB	ENSG00000100385.14			2208	0.683	0.1861	Yes
18	IFNGR1	ENSG00000027697.14			2329	0.669	0.1930	Yes
19	CD7	ENSG00000173762.8			2617	0.642	0.1954	Yes
20	SPI1	ENSG00000066336.11			3134	0.596	0.1915	Yes
21	PRF1	ENSG00000180644.8			3351	0.580	0.1947	Yes
22	LTB	ENSG00000227507.2			3397	0.576	0.2021	Yes
23	IL1B	ENSG00000125538.12			3430	0.572	0.2097	Yes
24	CCL4	ENSG00000275302.2			3550	0.564	0.2150	Yes
25	CD40LG	ENSG00000102245.7			3595	0.563	0.2222	Yes
26	CFP	ENSG00000126759.13			3748	0.554	0.2266	Yes
27	CD1D	ENSG00000158473.6			4133	0.535	0.2250	Yes
28	BCL3	ENSG00000069399.15			4224	0.529	0.2306	Yes
29	LCP2	ENSG00000043462.12			4413	0.519	0.2336	Yes
30	PRKCG	ENSG00000126583.11			4454	0.519	0.2402	Yes
31	CCND2	ENSG00000118971.8			4862	0.500	0.2376	Yes
32	HCLS1	ENSG00000180353.11			4907	0.497	0.2438	Yes
33	IL12B	ENSG00000113302.4			5068	0.486	0.2470	Yes
34	IL18RAP	ENSG00000115607.9			5756	0.445	0.2368	Yes
35	CD3G	ENSG00000160654.10			5767	0.445	0.2430	Yes
36	ACHE	ENSG00000087085.15			5861	0.441	0.2472	Yes
37	INHBB	ENSG00000163083.6			5957	0.435	0.2513	Yes
38	TLR1	ENSG00000174125.8			6430	0.410	0.2458	No
39	CD96	ENSG00000153283.13			6758	0.398	0.2436	No
40	ZAP70	ENSG00000115085.13			7283	0.376	0.2363	No
41	HLA-A	ENSG00000206503.13			8022	0.360	0.2236	No
42	HLA-G	ENSG00000204632.11			8061	0.359	0.2279	No
43	CCR5	ENSG00000160791.13			8627	0.348	0.2192	No
44	CCR1	ENSG00000163823.4			8802	0.344	0.2200	No
45	CCL19	ENSG00000172724.12			8838	0.342	0.2242	No
46	RPL3L	ENSG00000140986.8			8854	0.341	0.2288	No
47	IL4R	ENSG00000077238.14			8901	0.339	0.2326	No
48	GBP2	ENSG00000162645.13			9197	0.327	0.2302	No
49	TAP1	ENSG00000168394.11			9314	0.323	0.2321	No
50	MBL2	ENSG00000165471.6			9409	0.319	0.2345	No
51	CD2	ENSG00000116824.5			9412	0.319	0.2391	No
52	CCL5	ENSG00000271503.6			9843	0.317	0.2333	No
53	ICAM1	ENSG00000090339.9			9924	0.314	0.2359	No
54	CD74	ENSG00000019582.15			9998	0.311	0.2387	No
55	F2R	ENSG00000181104.7			10089	0.309	0.2410	No
56	CD3E	ENSG00000198851.9			10478	0.305	0.2360	No
57	ICOSLG	ENSG00000160223.17			10654	0.304	0.2362	No
58	SIT1	ENSG00000137078.9			10969	0.292	0.2328	No
59	HLA-E	ENSG00000204592.9			11025	0.290	0.2357	No
60	LCK	ENSG00000182866.17			11848	0.276	0.2197	No
61	IL11	ENSG00000095752.7			12510	0.254	0.2073	No
62	CTSS	ENSG00000163131.11			12694	0.248	0.2065	No
63	PF4	ENSG00000163737.4			12734	0.247	0.2091	No
64	F2	ENSG00000180210.14			12841	0.243	0.2101	No
65	STAB1	ENSG00000010327.10			13026	0.237	0.2091	No
66	TLR6	ENSG00000174130.12			13682	0.216	0.1962	No
67	CD40	ENSG00000101017.14			13803	0.213	0.1964	No
68	MAP4K1	ENSG00000104814.13			13908	0.209	0.1969	No
69	GPR65	ENSG00000140030.6			14045	0.204	0.1966	No
70	CCL11	ENSG00000172156.4			14358	0.196	0.1919	No
71	CCL2	ENSG00000108691.9			14738	0.183	0.1853	No
72	NOS2	ENSG00000007171.18			15003	0.173	0.1814	No
73	TRAF2	ENSG00000127191.18			15591	0.157	0.1694	No
74	CD247	ENSG00000198821.10			15755	0.152	0.1676	No
75	AARS	ENSG00000090861.15			15834	0.149	0.1679	No
76	IL2RA	ENSG00000134460.17			15953	0.146	0.1671	No
77	HLA-DRA	ENSG00000204287.14			16028	0.144	0.1674	No
78	CXCL9	ENSG00000138755.6			16417	0.133	0.1599	No
79	C2	ENSG00000166278.15			16704	0.125	0.1548	No
80	IL7	ENSG00000104432.14			16729	0.124	0.1560	No
81	LY75	ENSG00000054219.11			16900	0.120	0.1536	No
82	IFNGR2	ENSG00000159128.14			16912	0.119	0.1551	No
83	RPS3A	ENSG00000145425.10			17021	0.117	0.1542	No
84	IL4	ENSG00000113520.11			17263	0.110	0.1499	No
85	THY1	ENSG00000154096.13			17556	0.102	0.1443	No
86	CSF1	ENSG00000184371.14			17952	0.092	0.1360	No
87	LYN	ENSG00000254087.8			18130	0.087	0.1329	No
88	TLR3	ENSG00000164342.12			19180	0.060	0.1082	No
89	JAK2	ENSG00000096968.13			19235	0.058	0.1078	No
90	ST8SIA4	ENSG00000113532.13			19279	0.057	0.1075	No
91	PSMB10	ENSG00000205220.12			19937	0.040	0.0921	No
92	NPM1	ENSG00000181163.13			20296	0.031	0.0838	No
93	EREG	ENSG00000124882.4			20508	0.024	0.0790	No
94	PTPN6	ENSG00000111679.17			20832	0.017	0.0714	No
95	IFNAR2	ENSG00000159110.19			20879	0.015	0.0705	No
96	RIPK2	ENSG00000104312.8			21192	0.007	0.0630	No
97	RPS9	ENSG00000170889.14			21392	0.001	0.0581	No
98	IKBKB	ENSG00000104365.15			21539	-0.002	0.0546	No
99	AKT1	ENSG00000142208.16			21695	-0.006	0.0509	No
100	TNF	ENSG00000232810.4			21705	-0.006	0.0508	No
101	IL27RA	ENSG00000104998.4			21719	-0.007	0.0506	No
102	IL12RB1	ENSG00000096996.16			22290	-0.020	0.0370	No
103	CXCL13	ENSG00000156234.7			22603	-0.029	0.0298	No
104	B2M	ENSG00000166710.20			22947	-0.038	0.0219	No
105	HDAC9	ENSG00000048052.21			23030	-0.040	0.0205	No
106	GALNT1	ENSG00000141429.13			23031	-0.040	0.0211	No
107	RPS19	ENSG00000105372.8			23032	-0.040	0.0217	No
108	CD8A	ENSG00000153563.15			23057	-0.041	0.0217	No
109	APBB1	ENSG00000166313.19			23232	-0.046	0.0181	No
110	MMP9	ENSG00000100985.7			25181	-0.096	-0.0280	No
111	ACVR2A	ENSG00000121989.15			25237	-0.097	-0.0279	No
112	PRKCB	ENSG00000166501.14			25710	-0.111	-0.0378	No
113	TAPBP	ENSG00000231925.11			26413	-0.133	-0.0530	No
114	BCAT1	ENSG00000060982.15			26443	-0.133	-0.0517	No
115	MTIF2	ENSG00000085760.15			26449	-0.134	-0.0499	No
116	MRPL3	ENSG00000114686.9			26484	-0.135	-0.0488	No
117	SOCS1	ENSG00000185338.5			26705	-0.141	-0.0521	No
118	CCL13	ENSG00000181374.8			26725	-0.141	-0.0505	No
119	CD8B	ENSG00000172116.23			26744	-0.142	-0.0488	No
120	IL18	ENSG00000150782.12			26822	-0.144	-0.0486	No
121	TGFB1	ENSG00000105329.10			26855	-0.145	-0.0473	No
122	HLA-DOB	ENSG00000241106.8			26961	-0.148	-0.0477	No
123	CD79A	ENSG00000105369.9			27085	-0.152	-0.0484	No
124	EIF3D	ENSG00000100353.18			27222	-0.156	-0.0495	No
125	ITGB2	ENSG00000160255.18			27949	-0.179	-0.0646	No
126	CRTAM	ENSG00000109943.9			28500	-0.197	-0.0751	No
127	WARS	ENSG00000140105.18			28765	-0.204	-0.0786	No
128	HIF1A	ENSG00000100644.17			29230	-0.218	-0.0867	No
129	MAP3K7	ENSG00000135341.18			29362	-0.223	-0.0866	No
130	IL6	ENSG00000136244.12			29624	-0.231	-0.0896	No
131	CSK	ENSG00000103653.16			29702	-0.235	-0.0881	No
132	EIF3J	ENSG00000104131.13			30550	-0.261	-0.1049	No
133	RPL9	ENSG00000163682.16			30577	-0.262	-0.1017	No
134	STAT1	ENSG00000115415.18			30631	-0.263	-0.0992	No
135	UBE2D1	ENSG00000072401.15			30679	-0.265	-0.0964	No
136	GLMN	ENSG00000174842.17			30897	-0.273	-0.0977	No
137	EIF5A	ENSG00000132507.18			31039	-0.279	-0.0971	No
138	CCL22	ENSG00000102962.5			31587	-0.285	-0.1062	No
139	CD47	ENSG00000196776.16			31817	-0.290	-0.1076	No
140	ETS1	ENSG00000134954.14			31835	-0.291	-0.1037	No
141	ELF4	ENSG00000102034.16			32222	-0.306	-0.1087	No
142	EIF4G3	ENSG00000075151.20			32249	-0.307	-0.1048	No
143	CD80	ENSG00000121594.12			32342	-0.311	-0.1025	No
144	CCND3	ENSG00000112576.12			32532	-0.317	-0.1025	No
145	EIF3A	ENSG00000107581.13			32686	-0.323	-0.1015	No
146	CAPG	ENSG00000042493.16			32769	-0.326	-0.0987	No
147	EGFR	ENSG00000146648.18			32910	-0.332	-0.0973	No
148	HLA-DOA	ENSG00000204252.14			32977	-0.335	-0.0940	No
149	CD3D	ENSG00000167286.9			33274	-0.336	-0.0963	No
150	FAS	ENSG00000026103.22			34075	-0.344	-0.1107	No
151	STAT4	ENSG00000138378.19			34796	-0.361	-0.1230	No
152	FGR	ENSG00000000938.13			34978	-0.364	-0.1221	No
153	IL12A	ENSG00000168811.7			35073	-0.368	-0.1190	No
154	CDKN2A	ENSG00000147889.17			35138	-0.371	-0.1152	No
155	SOCS5	ENSG00000171150.9			35144	-0.371	-0.1099	No
156	TAP2	ENSG00000204267.15			35299	-0.378	-0.1081	No
157	DARS	ENSG00000115866.11			35546	-0.391	-0.1084	No
158	NCK1	ENSG00000158092.7			35806	-0.402	-0.1088	No
159	NCR1	ENSG00000189430.13			35885	-0.402	-0.1048	No
160	CD86	ENSG00000114013.16			35887	-0.402	-0.0989	No
161	UBE2N	ENSG00000177889.10			36090	-0.408	-0.0979	No
162	FCGR2B	ENSG00000072694.20			36148	-0.411	-0.0933	No
163	IL2RG	ENSG00000147168.12			36157	-0.412	-0.0874	No
164	RPL39	ENSG00000198918.8			36314	-0.417	-0.0851	No
165	ABI1	ENSG00000136754.17			36378	-0.420	-0.0805	No
166	CXCR3	ENSG00000186810.8			36572	-0.430	-0.0789	No
167	ABCE1	ENSG00000164163.11			36773	-0.438	-0.0774	No
168	INHBA	ENSG00000122641.11			36833	-0.442	-0.0724	No
169	DEGS1	ENSG00000143753.13			36839	-0.442	-0.0660	No
170	RARS	ENSG00000113643.9			36912	-0.447	-0.0612	No
171	HLA-DMA	ENSG00000204257.15			37225	-0.465	-0.0620	No
172	DYRK3	ENSG00000143479.17			37267	-0.468	-0.0562	No
173	SRGN	ENSG00000122862.5			37616	-0.495	-0.0574	No
174	HLA-DMB	ENSG00000242574.9			37679	-0.501	-0.0516	No
175	FLNA	ENSG00000196924.17			37839	-0.515	-0.0480	No
176	NME1	ENSG00000239672.7			38038	-0.530	-0.0450	No
177	GCNT1	ENSG00000187210.14			38293	-0.551	-0.0432	No
178	GZMB	ENSG00000100453.13			38501	-0.558	-0.0400	No
179	CD28	ENSG00000178562.18			39168	-0.615	-0.0473	No
180	BCL10	ENSG00000142867.14			39261	-0.619	-0.0405	No
181	ITK	ENSG00000113263.12			39406	-0.627	-0.0348	No
182	BRCA1	ENSG00000012048.22			39857	-0.687	-0.0357	No
183	CD4	ENSG00000010610.10			39926	-0.700	-0.0271	No
184	FYB1	ENSG00000082074.18			41002	-1.149	-0.0365	No
185	IL15	ENSG00000164136.17			41012	-1.156	-0.0199	No
186	PTPRC	ENSG00000081237.20			41122	-1.603	0.0010	No

Fig 2: HALLMARK_ALLOGRAFT_REJECTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_ALLOGRAFT_REJECTION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_ALLOGRAFT_REJECTION