Details for gene set HALLMARK_CHOLESTEROL_HOMEOSTASIS[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_CHOLESTEROL_HOMEOSTASIS
Enrichment Score (ES)	0.3746192
Normalized Enrichment Score (NES)	1.5384724
Nominal p-value	0.00913242
FDR q-value	0.04900585
FWER p-Value	0.219

Fig 1: Enrichment plot: HALLMARK_CHOLESTEROL_HOMEOSTASIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FABP5	ENSG00000164687.11			92	1.467	0.0587	Yes
2	LPL	ENSG00000175445.17			194	1.247	0.1081	Yes
3	GSTM2	ENSG00000213366.13			1162	0.824	0.1189	Yes
4	CXCL16	ENSG00000161921.15			1306	0.801	0.1487	Yes
5	CLU	ENSG00000120885.22			1659	0.752	0.1714	Yes
6	ABCA2	ENSG00000107331.17			2541	0.650	0.1769	Yes
7	ACSS2	ENSG00000131069.20			4226	0.529	0.1579	Yes
8	GUSB	ENSG00000169919.17			4282	0.525	0.1784	Yes
9	MVD	ENSG00000167508.12			4547	0.516	0.1934	Yes
10	DHCR7	ENSG00000172893.15			4598	0.514	0.2135	Yes
11	NFIL3	ENSG00000165030.4			4763	0.507	0.2306	Yes
12	PDK3	ENSG00000067992.15			4932	0.495	0.2471	Yes
13	CD9	ENSG00000010278.14			5422	0.464	0.2545	Yes
14	SEMA3B	ENSG00000012171.20			5425	0.463	0.2737	Yes
15	FBXO6	ENSG00000116663.11			5616	0.452	0.2879	Yes
16	HMGCR	ENSG00000113161.16			5676	0.449	0.3051	Yes
17	FADS2	ENSG00000134824.14			5709	0.447	0.3229	Yes
18	PNRC1	ENSG00000146278.11			6605	0.403	0.3179	Yes
19	LDLR	ENSG00000130164.13			6959	0.391	0.3256	Yes
20	EBP	ENSG00000147155.11			6973	0.391	0.3415	Yes
21	SC5D	ENSG00000109929.10			7132	0.384	0.3536	Yes
22	SCD	ENSG00000099194.6			7501	0.371	0.3601	Yes
23	TM7SF2	ENSG00000149809.15			7658	0.364	0.3714	Yes
24	FASN	ENSG00000169710.9			8136	0.356	0.3746	Yes
25	TMEM97	ENSG00000109084.14			9826	0.318	0.3467	No
26	CYP51A1	ENSG00000001630.17			10022	0.310	0.3549	No
27	MVK	ENSG00000110921.14			10148	0.305	0.3646	No
28	LGALS3	ENSG00000131981.16			11103	0.287	0.3533	No
29	HMGCS1	ENSG00000112972.15			11768	0.279	0.3487	No
30	PLSCR1	ENSG00000188313.13			12014	0.270	0.3540	No
31	FDFT1	ENSG00000079459.13			12228	0.263	0.3598	No
32	ALDOC	ENSG00000109107.14			12846	0.243	0.3548	No
33	FDPS	ENSG00000160752.14			13271	0.229	0.3541	No
34	SREBF2	ENSG00000198911.12			14589	0.187	0.3298	No
35	TP53INP1	ENSG00000164938.14			15662	0.154	0.3101	No
36	CBS	ENSG00000160200.17			15887	0.148	0.3108	No
37	SQLE	ENSG00000104549.12			16232	0.139	0.3082	No
38	CHKA	ENSG00000110721.12			16361	0.135	0.3107	No
39	ANXA13	ENSG00000104537.17			16693	0.125	0.3079	No
40	STX5	ENSG00000162236.12			16747	0.124	0.3117	No
41	ACAT2	ENSG00000120437.9			18961	0.066	0.2606	No
42	ECH1	ENSG00000104823.9			19400	0.054	0.2522	No
43	ANTXR2	ENSG00000163297.17			19752	0.045	0.2455	No
44	IDI1	ENSG00000067064.11			20552	0.023	0.2270	No
45	JAG1	ENSG00000101384.12			21019	0.012	0.2162	No
46	LSS	ENSG00000160285.15			21576	-0.003	0.2028	No
47	GPX8	ENSG00000164294.14			21726	-0.007	0.1994	No
48	HSD17B7	ENSG00000132196.14			22040	-0.015	0.1924	No
49	MAL2	ENSG00000147676.14			22223	-0.019	0.1888	No
50	LGMN	ENSG00000100600.15			22291	-0.020	0.1880	No
51	TRIB3	ENSG00000101255.11			22498	-0.027	0.1841	No
52	ALCAM	ENSG00000170017.12			22924	-0.037	0.1753	No
53	CTNNB1	ENSG00000168036.18			24288	-0.073	0.1451	No
54	NSDHL	ENSG00000147383.11			24881	-0.088	0.1344	No
55	AVPR1A	ENSG00000166148.3			25596	-0.108	0.1215	No
56	PPARG	ENSG00000132170.21			26008	-0.121	0.1165	No
57	ATF3	ENSG00000162772.17			27076	-0.151	0.0968	No
58	GLDC	ENSG00000178445.9			27339	-0.159	0.0971	No
59	ATXN2	ENSG00000204842.17			28622	-0.200	0.0742	No
60	PCYT2	ENSG00000185813.10			28931	-0.210	0.0754	No
61	GNAI1	ENSG00000127955.17			30005	-0.244	0.0594	No
62	S100A11	ENSG00000163191.6			30223	-0.251	0.0646	No
63	ADH4	ENSG00000198099.8			31853	-0.292	0.0370	No
64	STARD4	ENSG00000164211.13			32393	-0.313	0.0370	No
65	CPEB2	ENSG00000137449.16			32572	-0.319	0.0459	No
66	PMVK	ENSG00000163344.6			32790	-0.327	0.0542	No
67	ETHE1	ENSG00000105755.8			34645	-0.353	0.0238	No
68	TNFRSF12A	ENSG00000006327.13			34756	-0.359	0.0360	No
69	PLAUR	ENSG00000011422.12			35312	-0.379	0.0383	No
70	ACTG1	ENSG00000184009.12			36290	-0.416	0.0318	No
71	ERRFI1	ENSG00000116285.13			37565	-0.490	0.0211	No
72	ATF5	ENSG00000169136.11			38458	-0.558	0.0226	No
73	ANXA5	ENSG00000164111.15			40922	-1.038	0.0058	No

Fig 2: HALLMARK_CHOLESTEROL_HOMEOSTASIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_CHOLESTEROL_HOMEOSTASIS: Random ES distribution   
Gene set null distribution of ES for HALLMARK_CHOLESTEROL_HOMEOSTASIS