Details for gene set HALLMARK_COAGULATION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_COAGULATION
Enrichment Score (ES)	0.27937448
Normalized Enrichment Score (NES)	1.2811024
Nominal p-value	0.081120946
FDR q-value	0.13834743
FWER p-Value	0.932

Fig 1: Enrichment plot: HALLMARK_COAGULATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TF	ENSG00000091513.16			135	1.342	0.0235	Yes
2	HPN	ENSG00000105707.14			162	1.301	0.0488	Yes
3	TMPRSS6	ENSG00000187045.18			170	1.289	0.0743	Yes
4	TIMP1	ENSG00000102265.12			352	1.090	0.0916	Yes
5	S100A1	ENSG00000160678.11			463	1.030	0.1095	Yes
6	MST1	ENSG00000173531.15			585	0.985	0.1261	Yes
7	CTSB	ENSG00000164733.21			706	0.938	0.1419	Yes
8	C1S	ENSG00000182326.15			1233	0.811	0.1453	Yes
9	CLU	ENSG00000120885.22			1659	0.752	0.1499	Yes
10	PROC	ENSG00000115718.17			1960	0.710	0.1567	Yes
11	CFH	ENSG00000000971.15			2168	0.686	0.1654	Yes
12	GDA	ENSG00000119125.16			2733	0.629	0.1642	Yes
13	C1R	ENSG00000159403.18			2987	0.607	0.1701	Yes
14	P2RY1	ENSG00000169860.7			3067	0.601	0.1802	Yes
15	PDGFB	ENSG00000100311.17			3269	0.586	0.1869	Yes
16	LRP1	ENSG00000123384.14			3445	0.571	0.1941	Yes
17	PLG	ENSG00000122194.18			3746	0.554	0.1978	Yes
18	MMP10	ENSG00000166670.10			3778	0.552	0.2080	Yes
19	MASP2	ENSG00000009724.17			4725	0.509	0.1951	Yes
20	PROS1	ENSG00000184500.15			4767	0.507	0.2042	Yes
21	CFB	ENSG00000243649.8			4800	0.504	0.2135	Yes
22	SH2B2	ENSG00000160999.10			4826	0.502	0.2229	Yes
23	VWF	ENSG00000110799.13			5222	0.476	0.2228	Yes
24	C8G	ENSG00000176919.13			5255	0.474	0.2314	Yes
25	CD9	ENSG00000010278.14			5422	0.464	0.2366	Yes
26	MMP11	ENSG00000099953.10			5438	0.463	0.2455	Yes
27	ANG	ENSG00000214274.9			5563	0.456	0.2516	Yes
28	MSRB2	ENSG00000148450.13			5696	0.448	0.2573	Yes
29	F2RL2	ENSG00000164220.7			5734	0.446	0.2653	Yes
30	MMP1	ENSG00000196611.5			5783	0.444	0.2730	Yes
31	A2M	ENSG00000175899.14			5880	0.440	0.2794	Yes
32	CFD	ENSG00000197766.8			6918	0.393	0.2619	No
33	ITGA2	ENSG00000164171.11			7028	0.388	0.2670	No
34	FGG	ENSG00000171557.17			7287	0.376	0.2682	No
35	GP1BA	ENSG00000185245.8			7362	0.374	0.2739	No
36	KLKB1	ENSG00000164344.16			7475	0.372	0.2786	No
37	HNF4A	ENSG00000101076.16			8585	0.348	0.2585	No
38	SERPINC1	ENSG00000117601.13			8910	0.339	0.2573	No
39	PRSS23	ENSG00000150687.12			9200	0.327	0.2568	No
40	ITIH1	ENSG00000055957.11			9346	0.321	0.2597	No
41	MBL2	ENSG00000165471.6			9409	0.319	0.2645	No
42	CTSH	ENSG00000103811.16			9963	0.313	0.2573	No
43	APOA1	ENSG00000118137.9			10862	0.297	0.2413	No
44	ACOX2	ENSG00000168306.13			11842	0.277	0.2230	No
45	PROZ	ENSG00000126231.14			12317	0.260	0.2166	No
46	APOC1	ENSG00000130208.9			12577	0.252	0.2153	No
47	MMP14	ENSG00000157227.13			12590	0.252	0.2200	No
48	PF4	ENSG00000163737.4			12734	0.247	0.2215	No
49	F2	ENSG00000180210.14			12841	0.243	0.2237	No
50	MAFF	ENSG00000185022.12			13047	0.236	0.2234	No
51	C3	ENSG00000125730.17			13115	0.235	0.2265	No
52	LEFTY2	ENSG00000143768.13			13275	0.229	0.2272	No
53	PLEK	ENSG00000115956.10			13995	0.206	0.2138	No
54	MMP2	ENSG00000087245.13			14001	0.206	0.2178	No
55	BMP1	ENSG00000168487.19			14194	0.200	0.2171	No
56	APOC2	ENSG00000234906.10			14297	0.197	0.2185	No
57	DCT	ENSG00000080166.16			14795	0.181	0.2100	No
58	USP11	ENSG00000102226.9			15137	0.170	0.2051	No
59	HRG	ENSG00000113905.4			15955	0.146	0.1881	No
60	DUSP6	ENSG00000139318.8			16150	0.141	0.1861	No
61	C2	ENSG00000166278.15			16704	0.125	0.1752	No
62	SERPING1	ENSG00000149131.15			17821	0.096	0.1499	No
63	FBN1	ENSG00000166147.13			18163	0.087	0.1433	No
64	ISCU	ENSG00000136003.15			18869	0.069	0.1275	No
65	MMP8	ENSG00000118113.12			18994	0.065	0.1258	No
66	F12	ENSG00000131187.9			19233	0.059	0.1211	No
67	ITGB3	ENSG00000259207.7			19335	0.055	0.1198	No
68	TFPI2	ENSG00000105825.14			19794	0.044	0.1095	No
69	S100A13	ENSG00000189171.14			20350	0.029	0.0965	No
70	PECAM1	ENSG00000261371.6			20696	0.020	0.0885	No
71	FGA	ENSG00000171560.16			20943	0.014	0.0828	No
72	THBS1	ENSG00000137801.11			22033	-0.015	0.0566	No
73	DPP4	ENSG00000197635.10			22241	-0.019	0.0519	No
74	LGMN	ENSG00000100600.15			22291	-0.020	0.0511	No
75	THBD	ENSG00000178726.6			22330	-0.022	0.0506	No
76	SIRT2	ENSG00000068903.20			22423	-0.024	0.0488	No
77	CTSV	ENSG00000136943.11			22972	-0.039	0.0363	No
78	MMP15	ENSG00000102996.5			23626	-0.056	0.0215	No
79	CASP9	ENSG00000132906.18			23652	-0.057	0.0220	No
80	CTSO	ENSG00000256043.3			24619	-0.080	0.0000	No
81	LTA4H	ENSG00000111144.10			24714	-0.083	-0.0006	No
82	F13B	ENSG00000143278.4			24795	-0.085	-0.0008	No
83	SERPINA1	ENSG00000197249.13			25161	-0.095	-0.0079	No
84	MMP9	ENSG00000100985.7			25181	-0.096	-0.0064	No
85	F10	ENSG00000126218.12			25229	-0.097	-0.0056	No
86	CAPN5	ENSG00000149260.18			25882	-0.116	-0.0192	No
87	PREP	ENSG00000085377.14			25883	-0.116	-0.0169	No
88	CPQ	ENSG00000104324.16			26491	-0.135	-0.0290	No
89	FURIN	ENSG00000140564.12			26542	-0.136	-0.0275	No
90	PEF1	ENSG00000162517.13			26759	-0.143	-0.0299	No
91	TIMP3	ENSG00000100234.11			26802	-0.144	-0.0281	No
92	LAMP2	ENSG00000005893.15			26933	-0.147	-0.0283	No
93	RGN	ENSG00000130988.13			27173	-0.154	-0.0310	No
94	RABIF	ENSG00000183155.5			27378	-0.160	-0.0328	No
95	SPARC	ENSG00000113140.11			28014	-0.181	-0.0447	No
96	CRIP2	ENSG00000182809.10			28177	-0.185	-0.0449	No
97	GSN	ENSG00000148180.19			28530	-0.197	-0.0496	No
98	GNB2	ENSG00000172354.10			28962	-0.211	-0.0559	No
99	MMP7	ENSG00000137673.9			29674	-0.233	-0.0686	No
100	F8	ENSG00000185010.15			30159	-0.249	-0.0754	No
101	CTSK	ENSG00000143387.13			30865	-0.272	-0.0872	No
102	COMP	ENSG00000105664.11			31006	-0.277	-0.0850	No
103	F11	ENSG00000088926.13			31232	-0.285	-0.0848	No
104	GNG12	ENSG00000172380.6			32349	-0.311	-0.1058	No
105	C8B	ENSG00000021852.13			32651	-0.322	-0.1067	No
106	PLAU	ENSG00000122861.16			32703	-0.324	-0.1015	No
107	HTRA1	ENSG00000166033.13			32747	-0.326	-0.0961	No
108	C8A	ENSG00000157131.10			32976	-0.335	-0.0949	No
109	CFI	ENSG00000205403.13			35335	-0.380	-0.1448	No
110	PLAT	ENSG00000104368.18			35576	-0.392	-0.1429	No
111	C1QA	ENSG00000173372.17			35837	-0.402	-0.1412	No
112	RAPGEF3	ENSG00000079337.16			36449	-0.424	-0.1476	No
113	ANXA1	ENSG00000135046.14			36480	-0.425	-0.1399	No
114	CPB2	ENSG00000080618.16			36554	-0.430	-0.1331	No
115	RAC1	ENSG00000136238.18			37298	-0.471	-0.1418	No
116	CSRP1	ENSG00000159176.14			37484	-0.484	-0.1367	No
117	ARF4	ENSG00000168374.11			37528	-0.487	-0.1280	No
118	SERPINE1	ENSG00000106366.8			37533	-0.487	-0.1184	No
119	FYN	ENSG00000010810.17			37878	-0.518	-0.1164	No
120	WDR1	ENSG00000071127.17			37924	-0.522	-0.1071	No
121	ADAM9	ENSG00000168615.12			37925	-0.522	-0.0967	No
122	CPN1	ENSG00000120054.12			38342	-0.555	-0.0958	No
123	KLF7	ENSG00000118263.15			38734	-0.574	-0.0939	No
124	CAPN2	ENSG00000162909.18			39062	-0.608	-0.0897	No
125	OLR1	ENSG00000173391.9			39260	-0.619	-0.0822	No
126	DUSP14	ENSG00000276023.5			39970	-0.708	-0.0854	No
127	F3	ENSG00000117525.14			40005	-0.714	-0.0719	No
128	MMP3	ENSG00000149968.12			40668	-0.906	-0.0700	No
129	MEP1A	ENSG00000112818.10			40712	-0.927	-0.0526	No
130	FN1	ENSG00000115414.19			40842	-0.991	-0.0360	No
131	C9	ENSG00000113600.11			40949	-1.072	-0.0172	No
132	SERPINB2	ENSG00000197632.9			40988	-1.121	0.0042	No

Fig 2: HALLMARK_COAGULATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_COAGULATION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_COAGULATION