Details for gene set HALLMARK_DNA_REPAIR[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_DNA_REPAIR
Enrichment Score (ES)	-0.2394628
Normalized Enrichment Score (NES)	-1.2323029
Nominal p-value	0.075987846
FDR q-value	0.13616782
FWER p-Value	0.777

Fig 1: Enrichment plot: HALLMARK_DNA_REPAIR   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCNO	ENSG00000152669.9			1163	0.824	-0.0040	No
2	TAF1C	ENSG00000103168.16			2209	0.683	-0.0093	No
3	PDE4B	ENSG00000184588.18			4101	0.537	-0.0395	No
4	HCLS1	ENSG00000180353.11			4907	0.497	-0.0445	No
5	CMPK2	ENSG00000134326.11			5565	0.456	-0.0470	No
6	VPS37D	ENSG00000176428.6			5870	0.440	-0.0415	No
7	BCAM	ENSG00000187244.11			6634	0.402	-0.0482	No
8	POLB	ENSG00000070501.12			8084	0.358	-0.0729	No
9	NME3	ENSG00000103024.7			8569	0.348	-0.0744	No
10	MPG	ENSG00000103152.11			9361	0.320	-0.0843	No
11	POLL	ENSG00000166169.17			10815	0.298	-0.1109	No
12	ZNF707	ENSG00000181135.16			12020	0.270	-0.1323	No
13	AC139530.1	ENSG00000262049.1			12250	0.263	-0.1301	No
14	ADCY6	ENSG00000174233.11			12456	0.256	-0.1275	No
15	DDB2	ENSG00000134574.11			12599	0.251	-0.1236	No
16	TARBP2	ENSG00000139546.11			13162	0.233	-0.1304	No
17	POLR2H	ENSG00000163882.9			13722	0.215	-0.1376	No
18	ZNRD1	ENSG00000066379.15			13876	0.210	-0.1352	No
19	POLR2J	ENSG00000005075.15			13937	0.208	-0.1305	No
20	GTF2F1	ENSG00000125651.14			14092	0.203	-0.1283	No
21	ELL	ENSG00000105656.13			14500	0.191	-0.1325	No
22	POLR2A	ENSG00000181222.16			14631	0.186	-0.1302	No
23	SNAPC4	ENSG00000165684.4			14967	0.175	-0.1332	No
24	USP11	ENSG00000102226.9			15137	0.170	-0.1323	No
25	GPX4	ENSG00000167468.17			15215	0.168	-0.1292	No
26	AAAS	ENSG00000094914.14			15362	0.163	-0.1280	No
27	POLE4	ENSG00000115350.12			15368	0.163	-0.1233	No
28	VPS28	ENSG00000160948.14			15461	0.160	-0.1208	No
29	TAF10	ENSG00000166337.10			15814	0.150	-0.1250	No
30	UMPS	ENSG00000114491.14			15817	0.150	-0.1206	No
31	SMAD5	ENSG00000113658.18			15888	0.148	-0.1179	No
32	POLR1D	ENSG00000186184.18			16056	0.144	-0.1178	No
33	POLR2G	ENSG00000168002.12			16079	0.143	-0.1141	No
34	BCAP31	ENSG00000185825.17			16103	0.142	-0.1104	No
35	GTF3C5	ENSG00000148308.17			16214	0.139	-0.1090	No
36	SUPT5H	ENSG00000196235.14			16395	0.134	-0.1094	No
37	SRSF6	ENSG00000124193.16			16541	0.130	-0.1091	No
38	SEC61A1	ENSG00000058262.10			16746	0.124	-0.1104	No
39	NELFCD	ENSG00000101158.15			16860	0.121	-0.1096	No
40	RFC5	ENSG00000111445.14			16883	0.120	-0.1066	No
41	RPA2	ENSG00000117748.10			16945	0.118	-0.1046	No
42	POM121	ENSG00000196313.11			17139	0.114	-0.1059	No
43	NELFB	ENSG00000188986.7			17280	0.110	-0.1061	No
44	POLR2I	ENSG00000105258.9			17330	0.109	-0.1040	No
45	APRT	ENSG00000198931.11			17367	0.108	-0.1017	No
46	TAF6	ENSG00000106290.15			17371	0.108	-0.0986	No
47	RNMT	ENSG00000101654.17			17655	0.100	-0.1026	No
48	DGCR8	ENSG00000128191.16			17938	0.092	-0.1067	No
49	ERCC5	ENSG00000134899.21			17990	0.091	-0.1053	No
50	POLR2F	ENSG00000100142.15			18001	0.091	-0.1028	No
51	SSRP1	ENSG00000149136.9			18191	0.086	-0.1049	No
52	NT5C	ENSG00000125458.7			18324	0.083	-0.1057	No
53	RAD52	ENSG00000002016.18			18437	0.081	-0.1060	No
54	ADRM1	ENSG00000130706.13			18532	0.078	-0.1060	No
55	ERCC4	ENSG00000175595.14			18610	0.076	-0.1056	No
56	EDF1	ENSG00000107223.13			19194	0.060	-0.1181	No
57	ERCC3	ENSG00000163161.13			19714	0.046	-0.1294	No
58	NPR2	ENSG00000159899.14			19718	0.045	-0.1281	No
59	GMPR2	ENSG00000100938.17			19938	0.040	-0.1323	No
60	SURF1	ENSG00000148290.10			20388	0.028	-0.1424	No
61	GUK1	ENSG00000143774.16			20900	0.015	-0.1544	No
62	DDB1	ENSG00000167986.13			21018	0.012	-0.1569	No
63	SAC3D1	ENSG00000168061.15			21362	0.002	-0.1652	No
64	CANT1	ENSG00000171302.17			21563	-0.003	-0.1700	No
65	NELFE	ENSG00000204356.14			21837	-0.011	-0.1764	No
66	BRF2	ENSG00000104221.13			22069	-0.016	-0.1815	No
67	POLD4	ENSG00000175482.9			22165	-0.017	-0.1834	No
68	XPC	ENSG00000154767.14			22181	-0.018	-0.1832	No
69	TMED2	ENSG00000086598.11			22331	-0.022	-0.1862	No
70	SF3A3	ENSG00000183431.12			22336	-0.022	-0.1856	No
71	ERCC1	ENSG00000012061.15			22428	-0.024	-0.1871	No
72	POLR2C	ENSG00000102978.13			22510	-0.027	-0.1883	No
73	ITPA	ENSG00000125877.13			22703	-0.031	-0.1921	No
74	NFX1	ENSG00000086102.19			22748	-0.032	-0.1922	No
75	DGUOK	ENSG00000114956.20			22858	-0.035	-0.1938	No
76	RAE1	ENSG00000101146.13			23056	-0.041	-0.1974	No
77	SDCBP	ENSG00000137575.12			23102	-0.042	-0.1973	No
78	ARL6IP1	ENSG00000170540.15			23188	-0.045	-0.1980	No
79	ADA	ENSG00000196839.13			23425	-0.051	-0.2023	No
80	IMPDH2	ENSG00000178035.12			24066	-0.066	-0.2160	No
81	REV3L	ENSG00000009413.15			24276	-0.072	-0.2189	No
82	EIF1B	ENSG00000114784.4			24510	-0.077	-0.2223	No
83	NUDT21	ENSG00000167005.14			24528	-0.078	-0.2204	No
84	NUDT9	ENSG00000170502.13			24770	-0.085	-0.2238	No
85	ELOA	ENSG00000011007.12			24844	-0.087	-0.2230	No
86	POLA2	ENSG00000014138.9			24862	-0.087	-0.2209	No
87	CLP1	ENSG00000172409.6			25179	-0.095	-0.2257	No
88	MPC2	ENSG00000143158.11			25364	-0.101	-0.2272	No
89	AGO4	ENSG00000134698.11			25374	-0.101	-0.2245	No
90	GTF2B	ENSG00000137947.12			25384	-0.102	-0.2217	No
91	GSDME	ENSG00000105928.16			25472	-0.104	-0.2207	No
92	POLD1	ENSG00000062822.14			25827	-0.115	-0.2260	No
93	POLD3	ENSG00000077514.9			26261	-0.128	-0.2327	No
94	POLA1	ENSG00000101868.11			26537	-0.136	-0.2354	Yes
95	RFC2	ENSG00000049541.11			26606	-0.138	-0.2330	Yes
96	UPF3B	ENSG00000125351.11			26703	-0.141	-0.2312	Yes
97	CSTF3	ENSG00000176102.13			27011	-0.149	-0.2342	Yes
98	POLR3C	ENSG00000186141.9			27226	-0.156	-0.2349	Yes
99	TP53	ENSG00000141510.17			27245	-0.156	-0.2307	Yes
100	VPS37B	ENSG00000139722.7			27258	-0.157	-0.2263	Yes
101	DUT	ENSG00000128951.14			27355	-0.160	-0.2240	Yes
102	POLR1C	ENSG00000171453.20			27553	-0.166	-0.2239	Yes
103	POLR2K	ENSG00000147669.11			27760	-0.172	-0.2238	Yes
104	NCBP2	ENSG00000114503.11			27882	-0.176	-0.2215	Yes
105	GTF2A2	ENSG00000140307.11			28194	-0.186	-0.2236	Yes
106	LIG1	ENSG00000105486.14			28401	-0.193	-0.2230	Yes
107	DCTN4	ENSG00000132912.12			28497	-0.197	-0.2195	Yes
108	RRM2B	ENSG00000048392.11			28542	-0.198	-0.2147	Yes
109	MRPL40	ENSG00000185608.8			28602	-0.199	-0.2102	Yes
110	AK1	ENSG00000106992.19			28916	-0.209	-0.2117	Yes
111	TK2	ENSG00000166548.16			29736	-0.236	-0.2247	Yes
112	STX3	ENSG00000166900.17			29784	-0.237	-0.2188	Yes
113	RALA	ENSG00000006451.8			29860	-0.240	-0.2136	Yes
114	CDA	ENSG00000158825.6			29864	-0.240	-0.2066	Yes
115	SNAPC5	ENSG00000174446.13			29914	-0.241	-0.2006	Yes
116	POLR2D	ENSG00000144231.11			29937	-0.242	-0.1940	Yes
117	POLR2E	ENSG00000099817.12			30161	-0.249	-0.1921	Yes
118	RFC4	ENSG00000163918.10			30672	-0.265	-0.1967	Yes
119	ALYREF	ENSG00000183684.8			31002	-0.277	-0.1965	Yes
120	ERCC8	ENSG00000049167.14			31065	-0.279	-0.1898	Yes
121	NME4	ENSG00000103202.13			31135	-0.282	-0.1831	Yes
122	POLR3GL	ENSG00000121851.13			31740	-0.287	-0.1894	Yes
123	TSG101	ENSG00000074319.13			32189	-0.304	-0.1913	Yes
124	RBX1	ENSG00000100387.9			32483	-0.316	-0.1891	Yes
125	SUPT4H1	ENSG00000213246.7			32484	-0.316	-0.1798	Yes
126	DAD1	ENSG00000129562.11			34059	-0.343	-0.2080	Yes
127	TAF12	ENSG00000120656.11			34072	-0.344	-0.1982	Yes
128	COX17	ENSG00000138495.6			35127	-0.370	-0.2129	Yes
129	GTF2H3	ENSG00000111358.14			35764	-0.400	-0.2166	Yes
130	PNP	ENSG00000198805.11			36135	-0.411	-0.2135	Yes
131	RPA3	ENSG00000106399.11			36661	-0.434	-0.2134	Yes
132	HPRT1	ENSG00000165704.15			36862	-0.444	-0.2052	Yes
133	PCNA	ENSG00000132646.11			37166	-0.461	-0.1990	Yes
134	RFC3	ENSG00000133119.13			37532	-0.487	-0.1935	Yes
135	AK3	ENSG00000147853.17			37860	-0.517	-0.1862	Yes
136	TAF13	ENSG00000197780.10			37892	-0.520	-0.1716	Yes
137	NME1	ENSG00000239672.7			38038	-0.530	-0.1594	Yes
138	CETN2	ENSG00000147400.9			38135	-0.537	-0.1459	Yes
139	POLH	ENSG00000170734.11			38286	-0.550	-0.1333	Yes
140	PRIM1	ENSG00000198056.15			38325	-0.554	-0.1178	Yes
141	FEN1	ENSG00000168496.4			38636	-0.565	-0.1087	Yes
142	TAF9	ENSG00000273841.5			38720	-0.572	-0.0938	Yes
143	RAD51	ENSG00000051180.17			38806	-0.582	-0.0787	Yes
144	ZWINT	ENSG00000122952.17			39173	-0.616	-0.0694	Yes
145	NT5C3A	ENSG00000122643.21			39751	-0.667	-0.0638	Yes
146	GTF2H1	ENSG00000110768.12			40144	-0.740	-0.0515	Yes
147	ERCC2	ENSG00000104884.15			40308	-0.779	-0.0324	Yes
148	TYMS	ENSG00000176890.16			40602	-0.877	-0.0136	Yes
149	GTF2H5	ENSG00000272047.2			40695	-0.922	0.0114	Yes

Fig 2: HALLMARK_DNA_REPAIR   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_DNA_REPAIR: Random ES distribution   
Gene set null distribution of ES for HALLMARK_DNA_REPAIR