Details for gene set HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
Enrichment Score (ES)	-0.322878
Normalized Enrichment Score (NES)	-1.7185956
Nominal p-value	0.0
FDR q-value	0.0058997786
FWER p-Value	0.027

Fig 1: Enrichment plot: HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TGM2	ENSG00000198959.12			237	1.183	0.0100	No
2	FMOD	ENSG00000122176.12			266	1.161	0.0248	No
3	LAMA1	ENSG00000101680.15			292	1.136	0.0394	No
4	GPX7	ENSG00000116157.6			342	1.095	0.0528	No
5	TIMP1	ENSG00000102265.12			352	1.090	0.0671	No
6	SPOCK1	ENSG00000152377.14			444	1.039	0.0788	No
7	FBLN1	ENSG00000077942.19			705	0.938	0.0850	No
8	MGP	ENSG00000111341.10			913	0.879	0.0916	No
9	PCOLCE2	ENSG00000163710.9			1312	0.800	0.0926	No
10	EDIL3	ENSG00000164176.13			1748	0.740	0.0919	No
11	IGFBP3	ENSG00000146674.15			2420	0.661	0.0843	No
12	CDH6	ENSG00000113361.13			2559	0.647	0.0896	No
13	FOXC2	ENSG00000176692.8			2789	0.624	0.0923	No
14	CXCL6	ENSG00000124875.10			2918	0.612	0.0973	No
15	LUM	ENSG00000139329.5			3247	0.588	0.0972	No
16	LRP1	ENSG00000123384.14			3445	0.571	0.1000	No
17	IGFBP4	ENSG00000141753.7			3723	0.556	0.1007	No
18	FUCA1	ENSG00000179163.11			4024	0.539	0.1005	No
19	MEST	ENSG00000106484.16			4594	0.514	0.0935	No
20	SGCG	ENSG00000102683.7			4781	0.506	0.0957	No
21	CD44	ENSG00000026508.18			4934	0.495	0.0986	No
22	LAMA3	ENSG00000053747.16			5156	0.480	0.0996	No
23	NID2	ENSG00000087303.18			5592	0.454	0.0951	No
24	MMP1	ENSG00000196611.5			5783	0.444	0.0964	No
25	PCOLCE	ENSG00000106333.13			5878	0.440	0.0999	No
26	MAGEE1	ENSG00000198934.5			6412	0.412	0.0924	No
27	COL16A1	ENSG00000084636.18			6521	0.407	0.0952	No
28	PDGFRB	ENSG00000113721.14			6580	0.405	0.0992	No
29	WNT5A	ENSG00000114251.14			6657	0.401	0.1027	No
30	ITGA2	ENSG00000164171.11			7028	0.388	0.0989	No
31	CADM1	ENSG00000182985.17			7659	0.364	0.0883	No
32	PMEPA1	ENSG00000124225.16			8181	0.354	0.0803	No
33	BGN	ENSG00000182492.16			8477	0.352	0.0778	No
34	CXCL12	ENSG00000107562.16			8504	0.351	0.0819	No
35	APLP1	ENSG00000105290.12			9232	0.326	0.0685	No
36	PRSS2	ENSG00000275896.5			9771	0.319	0.0596	No
37	VCAM1	ENSG00000162692.12			9928	0.314	0.0600	No
38	SLC6A8	ENSG00000130821.16			9951	0.313	0.0637	No
39	CTHRC1	ENSG00000164932.13			11661	0.284	0.0257	No
40	BDNF	ENSG00000176697.19			11933	0.274	0.0228	No
41	GEM	ENSG00000164949.8			11976	0.272	0.0254	No
42	COL6A3	ENSG00000163359.15			12073	0.268	0.0266	No
43	TNFRSF11B	ENSG00000164761.9			12330	0.259	0.0238	No
44	MMP14	ENSG00000157227.13			12590	0.252	0.0209	No
45	CXCL1	ENSG00000163739.5			12872	0.242	0.0172	No
46	NNMT	ENSG00000166741.7			12911	0.241	0.0195	No
47	IGFBP2	ENSG00000115457.10			13426	0.224	0.0100	No
48	ITGB5	ENSG00000082781.12			13753	0.214	0.0049	No
49	MMP2	ENSG00000087245.13			14001	0.206	0.0016	No
50	BMP1	ENSG00000168487.19			14194	0.200	-0.0004	No
51	LAMA2	ENSG00000196569.12			14748	0.182	-0.0115	No
52	ANPEP	ENSG00000166825.14			14758	0.182	-0.0093	No
53	COL6A2	ENSG00000142173.15			14929	0.176	-0.0111	No
54	MSX1	ENSG00000163132.8			14975	0.174	-0.0099	No
55	VEGFA	ENSG00000112715.22			15227	0.167	-0.0138	No
56	FSTL3	ENSG00000070404.10			15423	0.161	-0.0164	No
57	PRRX1	ENSG00000116132.12			15553	0.158	-0.0174	No
58	PLOD3	ENSG00000106397.12			15907	0.147	-0.0241	No
59	PTHLH	ENSG00000087494.16			16391	0.134	-0.0341	No
60	RHOB	ENSG00000143878.10			16535	0.130	-0.0358	No
61	COL8A2	ENSG00000171812.13			16605	0.128	-0.0358	No
62	COL7A1	ENSG00000114270.17			16820	0.122	-0.0394	No
63	MCM7	ENSG00000166508.17			17495	0.104	-0.0545	No
64	THY1	ENSG00000154096.13			17556	0.102	-0.0546	No
65	NTM	ENSG00000182667.14			17916	0.093	-0.0621	No
66	FBN1	ENSG00000166147.13			18163	0.087	-0.0670	No
67	ADAM12	ENSG00000148848.14			18322	0.083	-0.0697	No
68	AREG	ENSG00000109321.11			18751	0.072	-0.0792	No
69	SLIT3	ENSG00000184347.14			18947	0.067	-0.0831	No
70	COL5A3	ENSG00000080573.7			19257	0.058	-0.0898	No
71	ITGB3	ENSG00000259207.7			19335	0.055	-0.0910	No
72	RGS4	ENSG00000117152.13			19418	0.053	-0.0923	No
73	THBS2	ENSG00000186340.15			19463	0.052	-0.0926	No
74	SFRP4	ENSG00000106483.12			19657	0.047	-0.0967	No
75	TFPI2	ENSG00000105825.14			19794	0.044	-0.0995	No
76	SAT1	ENSG00000130066.16			19807	0.043	-0.0992	No
77	CDH11	ENSG00000140937.14			20042	0.039	-0.1044	No
78	DCN	ENSG00000011465.17			20288	0.032	-0.1099	No
79	QSOX1	ENSG00000116260.17			20328	0.030	-0.1105	No
80	SNTB1	ENSG00000172164.15			20447	0.026	-0.1130	No
81	VCAN	ENSG00000038427.16			20990	0.012	-0.1261	No
82	SCG2	ENSG00000171951.5			21211	0.006	-0.1314	No
83	FBLN2	ENSG00000163520.14			21217	0.006	-0.1314	No
84	SDC4	ENSG00000124145.6			21749	-0.008	-0.1443	No
85	THBS1	ENSG00000137801.11			22033	-0.015	-0.1510	No
86	P3H1	ENSG00000117385.15			22141	-0.016	-0.1534	No
87	CD59	ENSG00000085063.16			22198	-0.018	-0.1545	No
88	CCN2	ENSG00000118523.6			22253	-0.019	-0.1556	No
89	COL5A1	ENSG00000130635.15			22567	-0.028	-0.1628	No
90	DPYSL3	ENSG00000113657.13			22812	-0.034	-0.1683	No
91	COL1A2	ENSG00000164692.17			23053	-0.041	-0.1737	No
92	COL1A1	ENSG00000108821.13			23206	-0.045	-0.1768	No
93	CRLF1	ENSG00000006016.11			23541	-0.054	-0.1842	No
94	VEGFC	ENSG00000150630.4			23777	-0.060	-0.1891	No
95	GADD45A	ENSG00000116717.13			23989	-0.064	-0.1934	No
96	NT5E	ENSG00000135318.12			24453	-0.076	-0.2037	No
97	COL3A1	ENSG00000168542.14			24737	-0.084	-0.2095	No
98	EFEMP2	ENSG00000172638.13			24938	-0.090	-0.2132	No
99	COPA	ENSG00000122218.16			25255	-0.097	-0.2196	No
100	PMP22	ENSG00000109099.15			25773	-0.113	-0.2307	No
101	PPIB	ENSG00000166794.4			25787	-0.113	-0.2295	No
102	FBN2	ENSG00000138829.12			26300	-0.129	-0.2403	No
103	COL4A2	ENSG00000134871.19			26354	-0.131	-0.2399	No
104	PVR	ENSG00000073008.15			26458	-0.134	-0.2406	No
105	GPC1	ENSG00000063660.9			26538	-0.136	-0.2407	No
106	TIMP3	ENSG00000100234.11			26802	-0.144	-0.2452	No
107	TGFB1	ENSG00000105329.10			26855	-0.145	-0.2445	No
108	TNFAIP3	ENSG00000118503.15			27043	-0.151	-0.2471	No
109	BASP1	ENSG00000176788.9			27329	-0.159	-0.2519	No
110	MATN2	ENSG00000132561.14			27429	-0.162	-0.2522	No
111	SERPINH1	ENSG00000149257.14			27457	-0.163	-0.2507	No
112	FAP	ENSG00000078098.14			27921	-0.177	-0.2596	No
113	SPARC	ENSG00000113140.11			28014	-0.181	-0.2594	No
114	NOTCH2	ENSG00000134250.20			28133	-0.185	-0.2599	No
115	COL11A1	ENSG00000060718.22			28377	-0.192	-0.2632	No
116	ECM2	ENSG00000106823.12			28489	-0.196	-0.2633	No
117	LAMC1	ENSG00000135862.6			28753	-0.203	-0.2670	No
118	WIPF1	ENSG00000115935.17			28844	-0.207	-0.2665	No
119	COL12A1	ENSG00000111799.21			29059	-0.214	-0.2688	No
120	FZD8	ENSG00000177283.7			29379	-0.224	-0.2736	No
121	IL6	ENSG00000136244.12			29624	-0.231	-0.2765	No
122	TPM2	ENSG00000198467.15			30252	-0.252	-0.2884	No
123	CCN1	ENSG00000142871.17			30290	-0.253	-0.2860	No
124	GAS1	ENSG00000180447.7			30508	-0.260	-0.2878	No
125	MXRA5	ENSG00000101825.8			30601	-0.263	-0.2865	No
126	EMP3	ENSG00000142227.11			30646	-0.264	-0.2841	No
127	DST	ENSG00000151914.20			30866	-0.272	-0.2858	No
128	PLOD1	ENSG00000083444.17			30871	-0.272	-0.2823	No
129	COMP	ENSG00000105664.11			31006	-0.277	-0.2818	No
130	SNAI2	ENSG00000019549.13			31053	-0.279	-0.2792	No
131	LOXL2	ENSG00000134013.16			31080	-0.280	-0.2761	No
132	FBLN5	ENSG00000140092.14			31116	-0.281	-0.2732	No
133	LAMC2	ENSG00000058085.15			31167	-0.284	-0.2707	No
134	MFAP5	ENSG00000197614.11			32055	-0.298	-0.2883	No
135	COL5A2	ENSG00000204262.14			32186	-0.304	-0.2874	No
136	HTRA1	ENSG00000166033.13			32747	-0.326	-0.2968	No
137	CAPG	ENSG00000042493.16			32769	-0.326	-0.2929	No
138	ABI3BP	ENSG00000154175.17			33553	-0.338	-0.3075	No
139	FAS	ENSG00000026103.22			34075	-0.344	-0.3157	No
140	PFN2	ENSG00000070087.14			34203	-0.350	-0.3141	No
141	FGF2	ENSG00000138685.15			34208	-0.350	-0.3095	No
142	TNFRSF12A	ENSG00000006327.13			34756	-0.359	-0.3181	Yes
143	COLGALT1	ENSG00000130309.11			34771	-0.360	-0.3136	Yes
144	LGALS1	ENSG00000100097.12			34849	-0.363	-0.3107	Yes
145	FSTL1	ENSG00000163430.12			35057	-0.368	-0.3108	Yes
146	MYLK	ENSG00000065534.18			35071	-0.368	-0.3062	Yes
147	PLAUR	ENSG00000011422.12			35312	-0.379	-0.3070	Yes
148	ELN	ENSG00000049540.17			35316	-0.380	-0.3020	Yes
149	PDLIM4	ENSG00000131435.13			35571	-0.392	-0.3030	Yes
150	ID2	ENSG00000115738.10			36059	-0.406	-0.3094	Yes
151	GREM1	ENSG00000166923.12			36324	-0.417	-0.3103	Yes
152	COL4A1	ENSG00000187498.16			36388	-0.420	-0.3062	Yes
153	ITGA5	ENSG00000161638.11			36500	-0.427	-0.3033	Yes
154	TNC	ENSG00000041982.16			36501	-0.427	-0.2976	Yes
155	ENO2	ENSG00000111674.9			36606	-0.431	-0.2943	Yes
156	SGCB	ENSG00000163069.12			36714	-0.436	-0.2911	Yes
157	TPM4	ENSG00000167460.17			36771	-0.438	-0.2867	Yes
158	SERPINE2	ENSG00000135919.13			36806	-0.440	-0.2816	Yes
159	DKK1	ENSG00000107984.10			36810	-0.441	-0.2758	Yes
160	POSTN	ENSG00000133110.15			36812	-0.441	-0.2699	Yes
161	INHBA	ENSG00000122641.11			36833	-0.442	-0.2645	Yes
162	SFRP1	ENSG00000104332.12			36849	-0.443	-0.2590	Yes
163	LRRC15	ENSG00000172061.8			37390	-0.477	-0.2658	Yes
164	TGFBR3	ENSG00000069702.11			37426	-0.479	-0.2603	Yes
165	SGCD	ENSG00000170624.13			37487	-0.484	-0.2553	Yes
166	SERPINE1	ENSG00000106366.8			37533	-0.487	-0.2499	Yes
167	ITGB1	ENSG00000150093.19			37687	-0.501	-0.2469	Yes
168	OXTR	ENSG00000180914.10			37721	-0.504	-0.2410	Yes
169	ITGAV	ENSG00000138448.12			37784	-0.511	-0.2357	Yes
170	TGFBI	ENSG00000120708.17			37818	-0.514	-0.2296	Yes
171	FLNA	ENSG00000196924.17			37839	-0.515	-0.2232	Yes
172	GJA1	ENSG00000152661.9			37853	-0.517	-0.2166	Yes
173	SLIT2	ENSG00000145147.20			38005	-0.528	-0.2133	Yes
174	DAB2	ENSG00000153071.15			38148	-0.538	-0.2096	Yes
175	CDH2	ENSG00000170558.9			38166	-0.540	-0.2028	Yes
176	TAGLN	ENSG00000149591.17			38295	-0.551	-0.1985	Yes
177	FERMT2	ENSG00000073712.15			38300	-0.551	-0.1913	Yes
178	GLIPR1	ENSG00000139278.10			38630	-0.564	-0.1918	Yes
179	SPP1	ENSG00000118785.14			38686	-0.569	-0.1855	Yes
180	TPM1	ENSG00000140416.21			38707	-0.572	-0.1784	Yes
181	VIM	ENSG00000026025.16			39637	-0.651	-0.1924	Yes
182	ECM1	ENSG00000143369.15			39921	-0.699	-0.1899	Yes
183	ACTA2	ENSG00000107796.13			39950	-0.704	-0.1812	Yes
184	GADD45B	ENSG00000099860.9			40019	-0.716	-0.1733	Yes
185	CXCL8	ENSG00000169429.11			40055	-0.722	-0.1645	Yes
186	CALD1	ENSG00000122786.20			40163	-0.745	-0.1572	Yes
187	CALU	ENSG00000128595.17			40186	-0.750	-0.1477	Yes
188	LOXL1	ENSG00000129038.16			40242	-0.763	-0.1389	Yes
189	PTX3	ENSG00000163661.4			40279	-0.771	-0.1295	Yes
190	SDC1	ENSG00000115884.11			40301	-0.777	-0.1196	Yes
191	JUN	ENSG00000177606.7			40305	-0.779	-0.1093	Yes
192	IL32	ENSG00000008517.16			40337	-0.787	-0.0995	Yes
193	MYL9	ENSG00000101335.10			40576	-0.868	-0.0938	Yes
194	CAP2	ENSG00000112186.12			40604	-0.877	-0.0827	Yes
195	MMP3	ENSG00000149968.12			40668	-0.906	-0.0722	Yes
196	FN1	ENSG00000115414.19			40842	-0.991	-0.0632	Yes
197	IL15	ENSG00000164136.17			41012	-1.156	-0.0519	Yes
198	MATN3	ENSG00000132031.13			41030	-1.191	-0.0364	Yes
199	PLOD2	ENSG00000152952.12			41057	-1.247	-0.0204	Yes
200	LOX	ENSG00000113083.14			41130	-1.714	0.0008	Yes

Fig 2: HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION