Details for gene set HALLMARK_ESTROGEN_RESPONSE_LATE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_ESTROGEN_RESPONSE_LATE
Enrichment Score (ES)	0.25172395
Normalized Enrichment Score (NES)	1.2075549
Nominal p-value	0.126703
FDR q-value	0.20792346
FWER p-Value	0.996

Fig 1: Enrichment plot: HALLMARK_ESTROGEN_RESPONSE_LATE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FABP5	ENSG00000164687.11			92	1.467	0.0183	Yes
2	CACNA2D2	ENSG00000007402.11			156	1.309	0.0352	Yes
3	SCNN1A	ENSG00000111319.13			344	1.095	0.0460	Yes
4	ST6GALNAC2	ENSG00000070731.11			621	0.969	0.0528	Yes
5	CISH	ENSG00000114737.15			726	0.933	0.0634	Yes
6	ALDH3A2	ENSG00000072210.19			745	0.927	0.0759	Yes
7	KRT19	ENSG00000171345.13			747	0.927	0.0889	Yes
8	SLC29A1	ENSG00000112759.18			778	0.917	0.1011	Yes
9	TJP3	ENSG00000105289.15			1019	0.855	0.1072	Yes
10	PDZK1	ENSG00000174827.13			1022	0.854	0.1191	Yes
11	OLFM1	ENSG00000130558.19			1121	0.833	0.1284	Yes
12	GAL	ENSG00000069482.7			1157	0.825	0.1391	Yes
13	CELSR2	ENSG00000143126.8			1203	0.817	0.1495	Yes
14	IGSF1	ENSG00000147255.19			1656	0.752	0.1490	Yes
15	EGR3	ENSG00000179388.9			1788	0.735	0.1562	Yes
16	PERP	ENSG00000112378.12			1793	0.734	0.1664	Yes
17	SLC22A5	ENSG00000197375.12			1879	0.720	0.1744	Yes
18	SERPINA5	ENSG00000188488.14			1979	0.708	0.1819	Yes
19	OPN3	ENSG00000054277.14			3184	0.592	0.1608	Yes
20	TPBG	ENSG00000146242.8			3275	0.586	0.1669	Yes
21	DUSP2	ENSG00000158050.5			3532	0.565	0.1685	Yes
22	IGFBP4	ENSG00000141753.7			3723	0.556	0.1717	Yes
23	MDK	ENSG00000110492.15			3765	0.553	0.1784	Yes
24	MAPK13	ENSG00000156711.17			3833	0.547	0.1845	Yes
25	LLGL2	ENSG00000073350.13			3880	0.546	0.1910	Yes
26	SNX10	ENSG00000086300.15			4367	0.522	0.1865	Yes
27	BCL2	ENSG00000171791.13			4386	0.520	0.1933	Yes
28	MEST	ENSG00000106484.16			4594	0.514	0.1955	Yes
29	DHCR7	ENSG00000172893.15			4598	0.514	0.2026	Yes
30	CD44	ENSG00000026508.18			4934	0.495	0.2014	Yes
31	CPE	ENSG00000109472.14			4995	0.492	0.2068	Yes
32	XRCC3	ENSG00000126215.14			5035	0.488	0.2128	Yes
33	NAB2	ENSG00000166886.13			5125	0.482	0.2173	Yes
34	MAPT	ENSG00000186868.15			5172	0.479	0.2229	Yes
35	CCN5	ENSG00000064205.10			5220	0.476	0.2285	Yes
36	CD9	ENSG00000010278.14			5422	0.464	0.2301	Yes
37	SEMA3B	ENSG00000012171.20			5425	0.463	0.2365	Yes
38	SERPINA3	ENSG00000196136.17			5867	0.440	0.2319	Yes
39	ST14	ENSG00000149418.11			5900	0.438	0.2373	Yes
40	CHST8	ENSG00000124302.13			5990	0.434	0.2412	Yes
41	IMPA2	ENSG00000141401.12			6164	0.425	0.2430	Yes
42	RPS6KA2	ENSG00000071242.12			6753	0.398	0.2342	Yes
43	SLC2A8	ENSG00000136856.18			6757	0.398	0.2397	Yes
44	ISG20	ENSG00000172183.15			6772	0.397	0.2449	Yes
45	NPY1R	ENSG00000164128.7			6929	0.393	0.2467	Yes
46	DNAJC12	ENSG00000108176.15			6977	0.390	0.2510	Yes
47	KLK10	ENSG00000129451.12			7356	0.374	0.2470	Yes
48	SLC27A2	ENSG00000140284.11			7378	0.373	0.2517	Yes
49	IL6ST	ENSG00000134352.20			8019	0.360	0.2412	No
50	CXCL12	ENSG00000107562.16			8504	0.351	0.2343	No
51	CALCR	ENSG00000004948.15			8664	0.348	0.2353	No
52	FKBP5	ENSG00000096060.14			8892	0.340	0.2345	No
53	CXCL14	ENSG00000145824.12			9066	0.333	0.2349	No
54	PRSS23	ENSG00000150687.12			9200	0.327	0.2363	No
55	RET	ENSG00000165731.20			9916	0.315	0.2233	No
56	PTGES	ENSG00000148344.11			10848	0.297	0.2047	No
57	METTL3	ENSG00000165819.12			10922	0.294	0.2070	No
58	EMP2	ENSG00000213853.10			11129	0.286	0.2060	No
59	KLK11	ENSG00000167757.14			11429	0.285	0.2027	No
60	ACOX2	ENSG00000168306.13			11842	0.277	0.1966	No
61	PRKAR2B	ENSG00000005249.13			12170	0.265	0.1923	No
62	ASS1	ENSG00000130707.18			12195	0.264	0.1954	No
63	FDFT1	ENSG00000079459.13			12228	0.263	0.1983	No
64	CA2	ENSG00000104267.10			12533	0.253	0.1945	No
65	GLA	ENSG00000102393.10			12631	0.250	0.1956	No
66	ANXA9	ENSG00000143412.10			12653	0.250	0.1986	No
67	SCUBE2	ENSG00000175356.13			12877	0.242	0.1965	No
68	RAPGEFL1	ENSG00000108352.12			13083	0.235	0.1948	No
69	CLIC3	ENSG00000169583.13			13128	0.234	0.1971	No
70	KLF4	ENSG00000136826.15			13176	0.233	0.1992	No
71	FOXC1	ENSG00000054598.9			13199	0.232	0.2019	No
72	PLXNB1	ENSG00000164050.13			13389	0.226	0.2005	No
73	LARGE1	ENSG00000133424.20			13853	0.211	0.1921	No
74	GJB3	ENSG00000188910.8			13913	0.209	0.1936	No
75	PTGER3	ENSG00000050628.20			14098	0.203	0.1919	No
76	DNAJC1	ENSG00000136770.11			14456	0.192	0.1859	No
77	WFS1	ENSG00000109501.13			14511	0.190	0.1873	No
78	NMU	ENSG00000109255.11			15293	0.165	0.1705	No
79	SCARB1	ENSG00000073060.16			15471	0.160	0.1685	No
80	ZFP36	ENSG00000128016.7			17058	0.116	0.1314	No
81	ITPK1	ENSG00000100605.17			17546	0.103	0.1209	No
82	HR	ENSG00000168453.15			17623	0.100	0.1205	No
83	CCNA1	ENSG00000133101.10			17734	0.098	0.1192	No
84	SIAH2	ENSG00000181788.4			17816	0.096	0.1185	No
85	FAM102A	ENSG00000167106.12			17926	0.093	0.1172	No
86	FOS	ENSG00000170345.10			17933	0.092	0.1183	No
87	CA12	ENSG00000074410.14			17955	0.092	0.1191	No
88	TSPAN13	ENSG00000106537.8			18017	0.090	0.1189	No
89	HSPB8	ENSG00000152137.6			18377	0.082	0.1113	No
90	ELOVL5	ENSG00000012660.14			18561	0.077	0.1079	No
91	ASCL1	ENSG00000139352.4			18678	0.074	0.1061	No
92	AREG	ENSG00000109321.11			18751	0.072	0.1053	No
93	TST	ENSG00000128311.14			19138	0.061	0.0968	No
94	JAK2	ENSG00000096968.13			19235	0.058	0.0953	No
95	AMFR	ENSG00000159461.15			19429	0.053	0.0913	No
96	GALE	ENSG00000117308.15			19512	0.051	0.0900	No
97	MICB	ENSG00000204516.10			19593	0.049	0.0887	No
98	AFF1	ENSG00000172493.20			19768	0.044	0.0851	No
99	TFPI2	ENSG00000105825.14			19794	0.044	0.0851	No
100	NXT1	ENSG00000132661.4			19931	0.040	0.0824	No
101	TFAP2C	ENSG00000087510.7			19936	0.040	0.0828	No
102	TIAM1	ENSG00000156299.13			20475	0.025	0.0700	No
103	PTPN6	ENSG00000111679.17			20832	0.017	0.0616	No
104	SFN	ENSG00000175793.12			21306	0.004	0.0501	No
105	TSTA3	ENSG00000104522.16			21337	0.003	0.0494	No
106	TRIM29	ENSG00000137699.17			21775	-0.009	0.0389	No
107	SOX3	ENSG00000134595.8			22396	-0.023	0.0241	No
108	XBP1	ENSG00000100219.16			22900	-0.036	0.0123	No
109	RAB31	ENSG00000168461.13			23170	-0.044	0.0063	No
110	ABHD2	ENSG00000140526.18			23280	-0.046	0.0043	No
111	HSPA4L	ENSG00000164070.12			23282	-0.046	0.0049	No
112	FGFR3	ENSG00000068078.18			24034	-0.065	-0.0125	No
113	ADD3	ENSG00000148700.15			24136	-0.068	-0.0140	No
114	BAG1	ENSG00000107262.23			24279	-0.073	-0.0164	No
115	LSR	ENSG00000105699.16			24349	-0.075	-0.0171	No
116	DCXR	ENSG00000169738.8			24886	-0.088	-0.0289	No
117	SERPINA1	ENSG00000197249.13			25161	-0.095	-0.0343	No
118	NBL1	ENSG00000158747.14			25372	-0.101	-0.0380	No
119	NRIP1	ENSG00000180530.11			25533	-0.106	-0.0404	No
120	SLC7A5	ENSG00000103257.9			25788	-0.113	-0.0450	No
121	SULT2B1	ENSG00000088002.11			25907	-0.117	-0.0462	No
122	PLAAT3	ENSG00000176485.11			26163	-0.125	-0.0507	No
123	SLC24A3	ENSG00000185052.12			26442	-0.133	-0.0556	No
124	FRK	ENSG00000111816.8			26728	-0.142	-0.0606	No
125	FARP1	ENSG00000152767.17			26841	-0.145	-0.0613	No
126	TPD52L1	ENSG00000111907.21			26861	-0.145	-0.0597	No
127	SLC1A4	ENSG00000115902.11			26994	-0.149	-0.0609	No
128	PAPSS2	ENSG00000198682.13			27309	-0.158	-0.0663	No
129	BLVRB	ENSG00000090013.11			27336	-0.159	-0.0647	No
130	MYB	ENSG00000118513.19			27404	-0.161	-0.0641	No
131	PCP4	ENSG00000183036.11			27414	-0.161	-0.0620	No
132	SLC9A3R1	ENSG00000109062.12			27565	-0.167	-0.0634	No
133	PGR	ENSG00000082175.15			27674	-0.170	-0.0636	No
134	UGDH	ENSG00000109814.12			27716	-0.171	-0.0622	No
135	SLC16A1	ENSG00000155380.11			27778	-0.173	-0.0613	No
136	DHRS2	ENSG00000100867.14			27922	-0.177	-0.0623	No
137	NCOR2	ENSG00000196498.13			28339	-0.191	-0.0698	No
138	TH	ENSG00000180176.14			28362	-0.191	-0.0676	No
139	ETFB	ENSG00000105379.9			28464	-0.195	-0.0673	No
140	DLG5	ENSG00000151208.17			28730	-0.203	-0.0710	No
141	JAK1	ENSG00000162434.13			28776	-0.204	-0.0692	No
142	PPIF	ENSG00000108179.14			29206	-0.218	-0.0766	No
143	SLC26A2	ENSG00000155850.7			29218	-0.218	-0.0738	No
144	TNNC1	ENSG00000114854.8			30104	-0.247	-0.0919	No
145	KRT13	ENSG00000171401.15			30497	-0.260	-0.0979	No
146	KCNK5	ENSG00000164626.9			30697	-0.266	-0.0990	No
147	PLAC1	ENSG00000170965.10			30704	-0.266	-0.0954	No
148	FKBP4	ENSG00000004478.8			30809	-0.270	-0.0942	No
149	LAMC2	ENSG00000058085.15			31167	-0.284	-0.0989	No
150	SORD	ENSG00000140263.14			31730	-0.287	-0.1086	No
151	LTF	ENSG00000012223.13			31945	-0.294	-0.1097	No
152	COX6C	ENSG00000164919.11			32702	-0.324	-0.1236	No
153	DYNLT3	ENSG00000165169.11			32854	-0.330	-0.1226	No
154	RBBP8	ENSG00000101773.19			32876	-0.331	-0.1185	No
155	CDC20	ENSG00000117399.14			34187	-0.349	-0.1456	No
156	CYP26B1	ENSG00000003137.8			34633	-0.353	-0.1515	No
157	KIF20A	ENSG00000112984.12			35970	-0.404	-0.1784	No
158	ID2	ENSG00000115738.10			36059	-0.406	-0.1749	No
159	RABEP1	ENSG00000029725.17			36276	-0.415	-0.1743	No
160	BTG3	ENSG00000154640.14			36289	-0.416	-0.1688	No
161	HPRT1	ENSG00000165704.15			36862	-0.444	-0.1765	No
162	MOCS2	ENSG00000164172.19			36880	-0.445	-0.1707	No
163	PDLIM3	ENSG00000154553.15			37084	-0.457	-0.1692	No
164	SGK1	ENSG00000118515.11			37317	-0.472	-0.1683	No
165	IL17RB	ENSG00000056736.10			37655	-0.498	-0.1695	No
166	UNC13B	ENSG00000198722.14			37748	-0.507	-0.1646	No
167	HOMER2	ENSG00000103942.13			37764	-0.508	-0.1579	No
168	TOB1	ENSG00000141232.5			37842	-0.516	-0.1525	No
169	GINS2	ENSG00000131153.9			37954	-0.524	-0.1479	No
170	PDCD4	ENSG00000150593.18			38083	-0.533	-0.1435	No
171	ALDH3B1	ENSG00000006534.16			38133	-0.537	-0.1372	No
172	BATF	ENSG00000156127.7			38174	-0.540	-0.1306	No
173	CCND1	ENSG00000110092.3			38307	-0.552	-0.1260	No
174	IDH2	ENSG00000182054.9			38704	-0.571	-0.1277	No
175	CHPT1	ENSG00000111666.11			38727	-0.573	-0.1202	No
176	ATP2B4	ENSG00000058668.14			38776	-0.578	-0.1132	No
177	CKB	ENSG00000166165.13			38832	-0.583	-0.1064	No
178	PLK4	ENSG00000142731.11			39267	-0.620	-0.1083	No
179	TOP2A	ENSG00000131747.15			39313	-0.624	-0.1006	No
180	ARL3	ENSG00000138175.9			39355	-0.624	-0.0929	No
181	ABCA3	ENSG00000167972.14			39450	-0.631	-0.0863	No
182	RNASEH2A	ENSG00000104889.6			39511	-0.636	-0.0789	No
183	PKP3	ENSG00000184363.10			39810	-0.676	-0.0766	No
184	CYP4F11	ENSG00000171903.16			40014	-0.715	-0.0716	No
185	CDH1	ENSG00000039068.19			40053	-0.722	-0.0623	No
186	CDC6	ENSG00000094804.12			40060	-0.723	-0.0523	No
187	MYOF	ENSG00000138119.17			40236	-0.761	-0.0459	No
188	STIL	ENSG00000123473.15			40411	-0.811	-0.0388	No
189	GPER1	ENSG00000164850.15			40441	-0.821	-0.0280	No
190	PRLR	ENSG00000113494.17			40839	-0.987	-0.0238	No
191	FLNB	ENSG00000136068.14			40977	-1.106	-0.0117	No
192	CAV1	ENSG00000105974.12			41003	-1.149	0.0039	No

Fig 2: HALLMARK_ESTROGEN_RESPONSE_LATE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_ESTROGEN_RESPONSE_LATE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_ESTROGEN_RESPONSE_LATE