Details for gene set HALLMARK_FATTY_ACID_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_FATTY_ACID_METABOLISM
Enrichment Score (ES)	-0.21968612
Normalized Enrichment Score (NES)	-1.115146
Nominal p-value	0.20588236
FDR q-value	0.29960614
FWER p-Value	0.979

Fig 1: Enrichment plot: HALLMARK_FATTY_ACID_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RDH16	ENSG00000139547.7			21	1.856	0.0402	No
2	EPHX1	ENSG00000143819.12			570	0.990	0.0486	No
3	ALDH3A2	ENSG00000072210.19			745	0.927	0.0647	No
4	ACADL	ENSG00000115361.8			1218	0.813	0.0710	No
5	CYP1A1	ENSG00000140465.14			1309	0.801	0.0863	No
6	HAO2	ENSG00000116882.14			1621	0.756	0.0953	No
7	SLC22A5	ENSG00000197375.12			1879	0.720	0.1049	No
8	ALDH3A1	ENSG00000108602.18			2386	0.664	0.1071	No
9	G0S2	ENSG00000123689.6			2663	0.637	0.1143	No
10	LTC4S	ENSG00000213316.10			2899	0.614	0.1221	No
11	D2HGDH	ENSG00000180902.18			2922	0.612	0.1350	No
12	DHCR24	ENSG00000116133.13			2975	0.608	0.1470	No
13	CD1D	ENSG00000158473.6			4133	0.535	0.1305	No
14	TP53INP2	ENSG00000078804.13			4295	0.524	0.1381	No
15	CA6	ENSG00000131686.15			4462	0.518	0.1454	No
16	AQP7	ENSG00000165269.13			4734	0.508	0.1500	No
17	GLUL	ENSG00000135821.18			5722	0.447	0.1357	No
18	ALDH1A1	ENSG00000165092.13			6111	0.428	0.1356	No
19	FMO1	ENSG00000010932.17			7182	0.381	0.1179	No
20	FASN	ENSG00000169710.9			8136	0.356	0.1025	No
21	ACSM3	ENSG00000005187.12			8535	0.350	0.1004	No
22	CYP4A22	ENSG00000162365.12			9690	0.319	0.0793	No
23	UBE2L6	ENSG00000156587.16			11121	0.287	0.0507	No
24	HMGCS1	ENSG00000112972.15			11768	0.279	0.0411	No
25	GAPDHS	ENSG00000105679.9			11950	0.273	0.0426	No
26	AUH	ENSG00000148090.11			12011	0.270	0.0471	No
27	GABARAPL1	ENSG00000139112.11			12462	0.255	0.0417	No
28	CA2	ENSG00000104267.10			12533	0.253	0.0456	No
29	MIF	ENSG00000240972.2			13196	0.232	0.0345	No
30	CIDEA	ENSG00000176194.18			13297	0.229	0.0371	No
31	GCDH	ENSG00000105607.13			13847	0.211	0.0284	No
32	ACADVL	ENSG00000072778.20			14036	0.205	0.0283	No
33	ACOT8	ENSG00000101473.17			14200	0.199	0.0287	No
34	MLYCD	ENSG00000103150.7			14450	0.192	0.0268	No
35	IDH3B	ENSG00000101365.21			15051	0.172	0.0160	No
36	CBR1	ENSG00000159228.13			15279	0.165	0.0140	No
37	GAD2	ENSG00000136750.13			16287	0.138	-0.0075	No
38	SDHA	ENSG00000073578.17			16659	0.127	-0.0138	No
39	ACSL4	ENSG00000068366.20			17156	0.113	-0.0234	No
40	ME1	ENSG00000065833.9			17317	0.109	-0.0249	No
41	MAOA	ENSG00000189221.9			17441	0.106	-0.0256	No
42	CPOX	ENSG00000080819.9			17654	0.100	-0.0285	No
43	HSD17B11	ENSG00000198189.11			17731	0.098	-0.0282	No
44	ACADM	ENSG00000117054.13			17744	0.098	-0.0264	No
45	ENO3	ENSG00000108515.17			18133	0.087	-0.0339	No
46	ACOX1	ENSG00000161533.12			18471	0.080	-0.0404	No
47	IDH3G	ENSG00000067829.19			18543	0.078	-0.0404	No
48	ELOVL5	ENSG00000012660.14			18561	0.077	-0.0392	No
49	PTPRG	ENSG00000144724.20			18586	0.077	-0.0381	No
50	ECI1	ENSG00000167969.13			18931	0.067	-0.0450	No
51	ACAT2	ENSG00000120437.9			18961	0.066	-0.0442	No
52	ECH1	ENSG00000104823.9			19400	0.054	-0.0537	No
53	DECR1	ENSG00000104325.7			19432	0.053	-0.0533	No
54	ACOT2	ENSG00000119673.14			19471	0.052	-0.0531	No
55	ACSL1	ENSG00000151726.14			19506	0.051	-0.0528	No
56	RDH11	ENSG00000072042.13			19531	0.051	-0.0523	No
57	INMT	ENSG00000241644.2			19717	0.045	-0.0558	No
58	APEX1	ENSG00000100823.12			20345	0.030	-0.0705	No
59	MCEE	ENSG00000124370.11			20426	0.027	-0.0718	No
60	NCAPH2	ENSG00000025770.19			20544	0.024	-0.0741	No
61	IDI1	ENSG00000067064.11			20552	0.023	-0.0738	No
62	NTHL1	ENSG00000065057.9			20578	0.023	-0.0739	No
63	CBR3	ENSG00000159231.6			20580	0.023	-0.0734	No
64	UROD	ENSG00000126088.14			20903	0.015	-0.0810	No
65	ACSS1	ENSG00000154930.15			21052	0.010	-0.0844	No
66	GRHPR	ENSG00000137106.18			21060	0.010	-0.0843	No
67	ERP29	ENSG00000089248.7			21087	0.009	-0.0847	No
68	ACO2	ENSG00000100412.16			21529	-0.002	-0.0955	No
69	NBN	ENSG00000104320.13			21733	-0.007	-0.1002	No
70	BPHL	ENSG00000137274.13			21993	-0.014	-0.1063	No
71	HSD17B7	ENSG00000132196.14			22040	-0.015	-0.1070	No
72	ALAD	ENSG00000148218.16			22286	-0.020	-0.1126	No
73	ACAA1	ENSG00000060971.18			22593	-0.028	-0.1194	No
74	HPGD	ENSG00000164120.14			22682	-0.030	-0.1209	No
75	IDH1	ENSG00000138413.13			22996	-0.039	-0.1277	No
76	PSME1	ENSG00000092010.15			23061	-0.041	-0.1283	No
77	ACADS	ENSG00000122971.9			23524	-0.053	-0.1384	No
78	AADAT	ENSG00000109576.14			23837	-0.061	-0.1447	No
79	BLVRA	ENSG00000106605.11			24009	-0.065	-0.1474	No
80	HADH	ENSG00000138796.16			24127	-0.067	-0.1488	No
81	CPT2	ENSG00000157184.7			24128	-0.068	-0.1473	No
82	ALDOA	ENSG00000149925.20			24530	-0.078	-0.1554	No
83	HIBCH	ENSG00000198130.16			24556	-0.079	-0.1543	No
84	REEP6	ENSG00000115255.11			24644	-0.081	-0.1546	No
85	FH	ENSG00000091483.6			24742	-0.084	-0.1551	No
86	NSDHL	ENSG00000147383.11			24881	-0.088	-0.1566	No
87	RETSAT	ENSG00000042445.14			25766	-0.113	-0.1757	No
88	PDHA1	ENSG00000131828.14			25806	-0.114	-0.1741	No
89	DLST	ENSG00000119689.15			26173	-0.125	-0.1803	No
90	ALDH9A1	ENSG00000143149.12			26176	-0.125	-0.1776	No
91	TDO2	ENSG00000151790.9			26514	-0.136	-0.1829	No
92	ACAA2	ENSG00000167315.18			26626	-0.139	-0.1825	No
93	HSD17B10	ENSG00000072506.12			26721	-0.141	-0.1817	No
94	SERINC1	ENSG00000111897.7			27077	-0.151	-0.1870	No
95	PTS	ENSG00000150787.8			27261	-0.157	-0.1881	No
96	CCDC58	ENSG00000160124.9			27502	-0.164	-0.1903	No
97	ECHS1	ENSG00000127884.5			27650	-0.169	-0.1902	No
98	AOC3	ENSG00000131471.7			27672	-0.170	-0.1870	No
99	UGDH	ENSG00000109814.12			27716	-0.171	-0.1843	No
100	SDHD	ENSG00000204370.12			27840	-0.175	-0.1835	No
101	HSD17B4	ENSG00000133835.16			27875	-0.175	-0.1804	No
102	SUCLG1	ENSG00000163541.12			28603	-0.199	-0.1938	No
103	MDH2	ENSG00000146701.12			28720	-0.203	-0.1922	No
104	CRAT	ENSG00000095321.17			29033	-0.213	-0.1951	No
105	HMGCL	ENSG00000117305.15			29172	-0.217	-0.1937	No
106	SUCLG2	ENSG00000172340.14			29509	-0.228	-0.1969	No
107	ADIPOR2	ENSG00000006831.10			30043	-0.245	-0.2045	No
108	CEL	ENSG00000170835.14			30665	-0.265	-0.2139	Yes
109	PDHB	ENSG00000168291.13			30731	-0.267	-0.2096	Yes
110	ETFDH	ENSG00000171503.12			30873	-0.272	-0.2071	Yes
111	PCBD1	ENSG00000166228.9			30899	-0.273	-0.2017	Yes
112	ECI2	ENSG00000198721.12			31163	-0.283	-0.2019	Yes
113	KMT5A	ENSG00000183955.13			31173	-0.284	-0.1959	Yes
114	GSTZ1	ENSG00000100577.19			31180	-0.284	-0.1898	Yes
115	ADH1C	ENSG00000248144.6			31787	-0.289	-0.1982	Yes
116	SUCLA2	ENSG00000136143.16			32023	-0.297	-0.1975	Yes
117	ACSL5	ENSG00000197142.10			32034	-0.298	-0.1912	Yes
118	HADHB	ENSG00000138029.14			32206	-0.305	-0.1886	Yes
119	CA4	ENSG00000167434.10			32228	-0.306	-0.1824	Yes
120	FABP2	ENSG00000145384.4			32464	-0.315	-0.1813	Yes
121	SDHC	ENSG00000143252.14			32711	-0.324	-0.1801	Yes
122	PPARA	ENSG00000186951.16			32874	-0.331	-0.1768	Yes
123	ODC1	ENSG00000115758.13			32958	-0.334	-0.1715	Yes
124	CD36	ENSG00000135218.19			32994	-0.336	-0.1650	Yes
125	GPD1	ENSG00000167588.13			33603	-0.341	-0.1724	Yes
126	HCCS	ENSG00000004961.15			34647	-0.354	-0.1901	Yes
127	HSPH1	ENSG00000120694.20			34716	-0.357	-0.1839	Yes
128	LGALS1	ENSG00000100097.12			34849	-0.363	-0.1791	Yes
129	SMS	ENSG00000102172.16			35034	-0.366	-0.1756	Yes
130	CPT1A	ENSG00000110090.13			35082	-0.368	-0.1687	Yes
131	H2AFZ	ENSG00000164032.12			35129	-0.370	-0.1617	Yes
132	ADSL	ENSG00000239900.12			35653	-0.396	-0.1657	Yes
133	GPD2	ENSG00000115159.16			36374	-0.420	-0.1741	Yes
134	VNN1	ENSG00000112299.8			36430	-0.423	-0.1662	Yes
135	ENO2	ENSG00000111674.9			36606	-0.431	-0.1610	Yes
136	OSTC	ENSG00000198856.13			36705	-0.436	-0.1538	Yes
137	MDH1	ENSG00000014641.19			36811	-0.441	-0.1467	Yes
138	IL4I1	ENSG00000104951.16			36916	-0.447	-0.1394	Yes
139	HSDL2	ENSG00000119471.15			37572	-0.491	-0.1446	Yes
140	CRYZ	ENSG00000116791.14			37658	-0.499	-0.1358	Yes
141	DLD	ENSG00000091140.14			37792	-0.512	-0.1278	Yes
142	HSP90AA1	ENSG00000080824.18			37823	-0.514	-0.1173	Yes
143	UROS	ENSG00000188690.15			37869	-0.518	-0.1070	Yes
144	ADH7	ENSG00000196344.11			37933	-0.523	-0.0971	Yes
145	METAP1	ENSG00000164024.12			38183	-0.541	-0.0913	Yes
146	MGLL	ENSG00000074416.14			38196	-0.542	-0.0797	Yes
147	PRDX6	ENSG00000117592.9			38289	-0.550	-0.0698	Yes
148	S100A10	ENSG00000197747.9			38623	-0.564	-0.0656	Yes
149	EHHADH	ENSG00000113790.11			39876	-0.690	-0.0810	Yes
150	YWHAH	ENSG00000128245.15			40295	-0.774	-0.0742	Yes
151	RAP1GDS1	ENSG00000138698.14			40376	-0.799	-0.0586	Yes
152	BCKDHB	ENSG00000083123.15			40514	-0.843	-0.0435	Yes
153	XIST	ENSG00000229807.12			40524	-0.847	-0.0251	Yes
154	LDHA	ENSG00000134333.14			40682	-0.914	-0.0089	Yes
155	BMPR1B	ENSG00000138696.11			40755	-0.937	0.0099	Yes

Fig 2: HALLMARK_FATTY_ACID_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_FATTY_ACID_METABOLISM: Random ES distribution   
Gene set null distribution of ES for HALLMARK_FATTY_ACID_METABOLISM