Details for gene set HALLMARK_GLYCOLYSIS[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_GLYCOLYSIS
Enrichment Score (ES)	-0.2442584
Normalized Enrichment Score (NES)	-1.3189654
Nominal p-value	0.016835017
FDR q-value	0.08047383
FWER p-Value	0.531

Fig 1: Enrichment plot: HALLMARK_GLYCOLYSIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SOX9	ENSG00000125398.8			43	1.704	0.0245	No
2	STC1	ENSG00000159167.12			211	1.227	0.0388	No
3	RRAGD	ENSG00000025039.15			702	0.939	0.0409	No
4	LHX9	ENSG00000143355.16			711	0.936	0.0547	No
5	GPC4	ENSG00000076716.9			1004	0.858	0.0604	No
6	CHST6	ENSG00000183196.10			1066	0.845	0.0716	No
7	GPC3	ENSG00000147257.14			1281	0.805	0.0784	No
8	IER3	ENSG00000137331.12			1454	0.779	0.0859	No
9	EGLN3	ENSG00000129521.14			1831	0.727	0.0876	No
10	ABCB6	ENSG00000115657.14			2070	0.696	0.0922	No
11	CLDN9	ENSG00000213937.4			2107	0.691	0.1017	No
12	DPYSL4	ENSG00000151640.13			2261	0.676	0.1081	No
13	IGFBP3	ENSG00000146674.15			2420	0.661	0.1141	No
14	B3GAT1	ENSG00000109956.13			2523	0.651	0.1214	No
15	AC010618.1	ENSG00000243771.1			2962	0.609	0.1198	No
16	TPBG	ENSG00000146242.8			3275	0.586	0.1209	No
17	PHKA2	ENSG00000044446.12			3378	0.578	0.1271	No
18	SPAG4	ENSG00000061656.10			3667	0.560	0.1285	No
19	CXCR4	ENSG00000121966.6			3819	0.548	0.1330	No
20	DDIT4	ENSG00000168209.5			4218	0.529	0.1312	No
21	GUSB	ENSG00000169919.17			4282	0.525	0.1375	No
22	HS2ST1	ENSG00000153936.17			4459	0.518	0.1410	No
23	ANKZF1	ENSG00000163516.14			4888	0.498	0.1380	No
24	PDK3	ENSG00000067992.15			4932	0.495	0.1444	No
25	CD44	ENSG00000026508.18			4934	0.495	0.1517	No
26	ANG	ENSG00000214274.9			5563	0.456	0.1432	No
27	G6PD	ENSG00000160211.19			6110	0.428	0.1363	No
28	ISG20	ENSG00000172183.15			6772	0.397	0.1261	No
29	CHST4	ENSG00000140835.9			6981	0.390	0.1269	No
30	EFNA3	ENSG00000143590.14			7095	0.385	0.1299	No
31	CHST1	ENSG00000175264.8			7383	0.373	0.1285	No
32	IDUA	ENSG00000127415.13			7505	0.371	0.1311	No
33	GCLC	ENSG00000001084.13			7671	0.364	0.1325	No
34	SAP30	ENSG00000164105.4			8180	0.354	0.1254	No
35	LDHC	ENSG00000166796.12			8497	0.351	0.1229	No
36	PAM	ENSG00000145730.20			9186	0.328	0.1111	No
37	HS6ST2	ENSG00000171004.18			10150	0.305	0.0921	No
38	GYS2	ENSG00000111713.3			10679	0.303	0.0838	No
39	MED24	ENSG00000008838.20			10756	0.300	0.0864	No
40	LCT	ENSG00000115850.10			10798	0.299	0.0899	No
41	GMPPA	ENSG00000144591.18			11770	0.279	0.0704	No
42	FUT8	ENSG00000033170.16			11841	0.277	0.0728	No
43	GAPDHS	ENSG00000105679.9			11950	0.273	0.0742	No
44	CACNA1H	ENSG00000196557.13			11974	0.272	0.0778	No
45	B4GALT7	ENSG00000027847.14			12752	0.246	0.0625	No
46	MIF	ENSG00000240972.2			13196	0.232	0.0551	No
47	FAM162A	ENSG00000114023.15			13232	0.231	0.0577	No
48	NASP	ENSG00000132780.17			13329	0.227	0.0588	No
49	PPFIA4	ENSG00000143847.15			13557	0.220	0.0566	No
50	MERTK	ENSG00000153208.17			13585	0.219	0.0592	No
51	SLC37A4	ENSG00000137700.18			13897	0.209	0.0547	No
52	GLCE	ENSG00000138604.10			14037	0.205	0.0544	No
53	IRS2	ENSG00000185950.9			14166	0.200	0.0543	No
54	BIK	ENSG00000100290.3			14260	0.198	0.0550	No
55	ALDOB	ENSG00000136872.20			14273	0.198	0.0576	No
56	XYLT2	ENSG00000015532.10			14701	0.184	0.0500	No
57	AK4	ENSG00000162433.15			14736	0.183	0.0519	No
58	VEGFA	ENSG00000112715.22			15227	0.167	0.0424	No
59	PKP2	ENSG00000057294.14			15288	0.165	0.0434	No
60	B3GAT3	ENSG00000149541.10			15425	0.161	0.0425	No
61	SRD5A3	ENSG00000128039.11			15695	0.153	0.0382	No
62	ZNF292	ENSG00000188994.13			15818	0.150	0.0375	No
63	CTH	ENSG00000116761.12			17265	0.110	0.0039	No
64	ME1	ENSG00000065833.9			17317	0.109	0.0043	No
65	PYGL	ENSG00000100504.17			17804	0.096	-0.0062	No
66	AGRN	ENSG00000188157.15			18021	0.090	-0.0101	No
67	IL13RA1	ENSG00000131724.11			18289	0.084	-0.0154	No
68	TALDO1	ENSG00000177156.11			18425	0.081	-0.0174	No
69	CHPF	ENSG00000123989.14			18686	0.074	-0.0227	No
70	POLR3K	ENSG00000161980.6			18832	0.070	-0.0252	No
71	COG2	ENSG00000135775.14			18893	0.068	-0.0256	No
72	GALE	ENSG00000117308.15			19512	0.051	-0.0399	No
73	STC2	ENSG00000113739.10			19602	0.048	-0.0414	No
74	ALG1	ENSG00000033011.12			19777	0.044	-0.0450	No
75	RBCK1	ENSG00000125826.20			20153	0.035	-0.0536	No
76	DCN	ENSG00000011465.17			20288	0.032	-0.0564	No
77	QSOX1	ENSG00000116260.17			20328	0.030	-0.0569	No
78	ALDH7A1	ENSG00000164904.18			20671	0.020	-0.0649	No
79	PSMC4	ENSG00000013275.8			20810	0.018	-0.0680	No
80	VCAN	ENSG00000038427.16			20990	0.012	-0.0722	No
81	DSC2	ENSG00000134755.17			21141	0.007	-0.0758	No
82	TSTA3	ENSG00000104522.16			21337	0.003	-0.0805	No
83	HK2	ENSG00000159399.9			21414	0.001	-0.0823	No
84	MIOX	ENSG00000100253.13			21458	0.000	-0.0834	No
85	AGL	ENSG00000162688.17			21699	-0.006	-0.0892	No
86	GMPPB	ENSG00000173540.12			21953	-0.013	-0.0951	No
87	PAXIP1	ENSG00000157212.19			22245	-0.019	-0.1020	No
88	COL5A1	ENSG00000130635.15			22567	-0.028	-0.1094	No
89	CHPF2	ENSG00000033100.16			22673	-0.030	-0.1115	No
90	KDELR3	ENSG00000100196.11			22740	-0.032	-0.1126	No
91	IDH1	ENSG00000138413.13			22996	-0.039	-0.1183	No
92	VLDLR	ENSG00000147852.16			23181	-0.045	-0.1221	No
93	AC074143.1	ENSG00000265690.7			23501	-0.052	-0.1291	No
94	GLRX	ENSG00000173221.14			23563	-0.054	-0.1298	No
95	SLC35A3	ENSG00000117620.15			23630	-0.056	-0.1305	No
96	GALK1	ENSG00000108479.12			23871	-0.062	-0.1355	No
97	B3GNT3	ENSG00000179913.11			23955	-0.064	-0.1365	No
98	EXT1	ENSG00000182197.11			24146	-0.068	-0.1402	No
99	TPST1	ENSG00000169902.15			24255	-0.072	-0.1417	No
100	SLC25A10	ENSG00000183048.12			24351	-0.075	-0.1429	No
101	GOT2	ENSG00000125166.13			24356	-0.075	-0.1419	No
102	NT5E	ENSG00000135318.12			24453	-0.076	-0.1431	No
103	ALDOA	ENSG00000149925.20			24530	-0.078	-0.1438	No
104	NSDHL	ENSG00000147383.11			24881	-0.088	-0.1510	No
105	CHST12	ENSG00000136213.10			25100	-0.093	-0.1550	No
106	SLC16A3	ENSG00000141526.16			25503	-0.105	-0.1632	No
107	CYB5A	ENSG00000166347.19			25515	-0.106	-0.1619	No
108	CAPN5	ENSG00000149260.18			25882	-0.116	-0.1691	No
109	BPNT1	ENSG00000162813.18			25902	-0.117	-0.1678	No
110	ALDH9A1	ENSG00000143149.12			26176	-0.125	-0.1726	No
111	PFKFB1	ENSG00000158571.11			26334	-0.130	-0.1745	No
112	GPC1	ENSG00000063660.9			26538	-0.136	-0.1774	No
113	AKR1A1	ENSG00000117448.13			26839	-0.145	-0.1825	No
114	TPI1	ENSG00000111669.15			26955	-0.148	-0.1831	No
115	B3GALT6	ENSG00000176022.7			26956	-0.148	-0.1809	No
116	CLDN3	ENSG00000165215.6			27202	-0.155	-0.1846	No
117	CASP6	ENSG00000138794.10			27327	-0.159	-0.1852	No
118	HDLBP	ENSG00000115677.17			27421	-0.162	-0.1851	No
119	CHST2	ENSG00000175040.6			27669	-0.170	-0.1886	No
120	ARTN	ENSG00000117407.17			27989	-0.180	-0.1937	No
121	MXI1	ENSG00000119950.21			28064	-0.183	-0.1927	No
122	HOMER1	ENSG00000152413.15			28384	-0.192	-0.1976	No
123	MDH2	ENSG00000146701.12			28720	-0.203	-0.2028	No
124	ANGPTL4	ENSG00000167772.12			28905	-0.208	-0.2041	No
125	MPI	ENSG00000178802.18			29168	-0.217	-0.2073	No
126	ELF3	ENSG00000163435.16			29394	-0.224	-0.2094	No
127	GPR87	ENSG00000138271.6			29449	-0.226	-0.2074	No
128	TXN	ENSG00000136810.13			29623	-0.231	-0.2081	No
129	PMM2	ENSG00000140650.12			29718	-0.235	-0.2069	No
130	B4GALT4	ENSG00000121578.13			29751	-0.236	-0.2041	No
131	HAX1	ENSG00000143575.14			29941	-0.242	-0.2051	No
132	PC	ENSG00000173599.15			30008	-0.244	-0.2031	No
133	CLN6	ENSG00000128973.13			30476	-0.259	-0.2106	No
134	GAL3ST1	ENSG00000128242.13			30563	-0.261	-0.2088	No
135	PYGB	ENSG00000100994.12			30687	-0.265	-0.2078	No
136	FKBP4	ENSG00000004478.8			30809	-0.270	-0.2067	No
137	PLOD1	ENSG00000083444.17			30871	-0.272	-0.2041	No
138	LHPP	ENSG00000107902.14			30879	-0.273	-0.2002	No
139	GALK2	ENSG00000156958.15			30946	-0.275	-0.1977	No
140	ERO1A	ENSG00000197930.13			31946	-0.294	-0.2177	No
141	COPB2	ENSG00000184432.10			32009	-0.297	-0.2148	No
142	GNE	ENSG00000159921.16			32141	-0.302	-0.2135	No
143	GOT1	ENSG00000120053.12			32193	-0.304	-0.2101	No
144	HSPA5	ENSG00000044574.8			32282	-0.308	-0.2077	No
145	SOD1	ENSG00000142168.14			32307	-0.310	-0.2036	No
146	SDHC	ENSG00000143252.14			32711	-0.324	-0.2086	No
147	GNPDA1	ENSG00000113552.16			32802	-0.328	-0.2059	No
148	EXT2	ENSG00000151348.14			32845	-0.330	-0.2020	No
149	EGFR	ENSG00000146648.18			32910	-0.332	-0.1986	No
150	ECD	ENSG00000122882.11			33598	-0.340	-0.2102	No
151	RPE	ENSG00000197713.15			34819	-0.362	-0.2346	No
152	GFPT1	ENSG00000198380.12			34838	-0.363	-0.2296	No
153	SDC3	ENSG00000162512.16			35439	-0.385	-0.2385	Yes
154	PFKP	ENSG00000067057.17			35494	-0.388	-0.2340	Yes
155	P4HA2	ENSG00000072682.18			35623	-0.395	-0.2312	Yes
156	ENO1	ENSG00000074800.16			35638	-0.395	-0.2256	Yes
157	PGM2	ENSG00000169299.14			35669	-0.396	-0.2204	Yes
158	NDST3	ENSG00000164100.9			35776	-0.401	-0.2170	Yes
159	KIF20A	ENSG00000112984.12			35970	-0.404	-0.2157	Yes
160	TKTL1	ENSG00000007350.17			36144	-0.411	-0.2137	Yes
161	PKM	ENSG00000067225.18			36313	-0.416	-0.2116	Yes
162	ENO2	ENSG00000111674.9			36606	-0.431	-0.2123	Yes
163	MDH1	ENSG00000014641.19			36811	-0.441	-0.2107	Yes
164	RARS	ENSG00000113643.9			36912	-0.447	-0.2064	Yes
165	KIF2A	ENSG00000068796.16			36994	-0.452	-0.2016	Yes
166	PPIA	ENSG00000196262.14			37055	-0.456	-0.1963	Yes
167	CITED2	ENSG00000164442.10			37189	-0.463	-0.1926	Yes
168	NANP	ENSG00000170191.5			37278	-0.469	-0.1877	Yes
169	P4HA1	ENSG00000122884.12			37364	-0.475	-0.1827	Yes
170	HMMR	ENSG00000072571.20			37412	-0.479	-0.1766	Yes
171	B4GALT2	ENSG00000117411.16			37504	-0.485	-0.1716	Yes
172	SLC25A13	ENSG00000004864.13			37677	-0.500	-0.1683	Yes
173	DLD	ENSG00000091140.14			37792	-0.512	-0.1634	Yes
174	PGK1	ENSG00000102144.15			37804	-0.512	-0.1560	Yes
175	TGFBI	ENSG00000120708.17			37818	-0.514	-0.1486	Yes
176	NDUFV3	ENSG00000160194.18			37851	-0.517	-0.1417	Yes
177	AK3	ENSG00000147853.17			37860	-0.517	-0.1341	Yes
178	CENPA	ENSG00000115163.15			37993	-0.527	-0.1295	Yes
179	B4GALT1	ENSG00000086062.12			38033	-0.530	-0.1225	Yes
180	PGAM1	ENSG00000171314.9			38092	-0.534	-0.1159	Yes
181	GYS1	ENSG00000104812.15			38103	-0.535	-0.1081	Yes
182	SDC2	ENSG00000169439.12			38187	-0.541	-0.1021	Yes
183	ME2	ENSG00000082212.13			38613	-0.563	-0.1040	Yes
184	AURKA	ENSG00000087586.17			38638	-0.565	-0.0961	Yes
185	PPP2CB	ENSG00000104695.13			38708	-0.572	-0.0892	Yes
186	FBP2	ENSG00000130957.5			38770	-0.577	-0.0821	Yes
187	ARPP19	ENSG00000128989.10			38877	-0.588	-0.0759	Yes
188	STMN1	ENSG00000117632.23			38971	-0.598	-0.0692	Yes
189	DEPDC1	ENSG00000024526.17			39009	-0.602	-0.0611	Yes
190	TGFA	ENSG00000163235.16			39092	-0.612	-0.0539	Yes
191	MET	ENSG00000105976.15			39317	-0.624	-0.0500	Yes
192	CDK1	ENSG00000170312.16			39453	-0.632	-0.0439	Yes
193	ADORA2B	ENSG00000170425.3			39882	-0.692	-0.0440	Yes
194	SDC1	ENSG00000115884.11			40301	-0.777	-0.0425	Yes
195	LDHA	ENSG00000134333.14			40682	-0.914	-0.0381	Yes
196	UGP2	ENSG00000169764.15			40772	-0.945	-0.0261	Yes
197	PRPS1	ENSG00000147224.11			40992	-1.129	-0.0146	Yes
198	PLOD2	ENSG00000152952.12			41057	-1.247	0.0025	Yes

Fig 2: HALLMARK_GLYCOLYSIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_GLYCOLYSIS: Random ES distribution   
Gene set null distribution of ES for HALLMARK_GLYCOLYSIS