Details for gene set HALLMARK

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_HYPOXIA
Enrichment Score (ES)	-0.2529327
Normalized Enrichment Score (NES)	-1.3433015
Nominal p-value	0.017667845
FDR q-value	0.07220255
FWER p-Value	0.471

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	STC1	ENSG00000159167.12	211	1.227	0.0122	No
2	TGM2	ENSG00000198959.12	237	1.183	0.0283	No
3	TPD52	ENSG00000076554.15	340	1.096	0.0412	No
4	EFNA1	ENSG00000169242.12	382	1.073	0.0554	No
5	INHA	ENSG00000123999.5	391	1.069	0.0703	No
6	CP	ENSG00000047457.14	500	1.015	0.0819	No
7	RRAGD	ENSG00000025039.15	702	0.939	0.0903	No
8	NEDD4L	ENSG00000049759.18	1003	0.858	0.0951	No
9	GPC4	ENSG00000076716.9	1004	0.858	0.1072	No
10	GPC3	ENSG00000147257.14	1281	0.805	0.1118	No
11	IER3	ENSG00000137331.12	1454	0.779	0.1186	No
12	CDKN1C	ENSG00000129757.13	1596	0.759	0.1259	No
13	DPYSL4	ENSG00000151640.13	2261	0.676	0.1192	No
14	IGFBP3	ENSG00000146674.15	2420	0.661	0.1247	No
15	SLC6A6	ENSG00000131389.17	2725	0.630	0.1261	No
16	MAP3K1	ENSG00000095015.6	3142	0.596	0.1244	No
17	PDGFB	ENSG00000100311.17	3269	0.586	0.1296	No
18	TPBG	ENSG00000146242.8	3275	0.586	0.1377	No
19	KIF5A	ENSG00000155980.12	3665	0.560	0.1361	No
20	CXCR4	ENSG00000121966.6	3819	0.548	0.1401	No
21	BRS3	ENSG00000102239.5	3905	0.545	0.1457	No
22	MT2A	ENSG00000125148.7	3939	0.543	0.1526	No
23	DDIT4	ENSG00000168209.5	4218	0.529	0.1533	No
24	CDKN1B	ENSG00000111276.11	4380	0.521	0.1567	No
25	KLHL24	ENSG00000114796.16	4382	0.521	0.1640	No
26	BCL2	ENSG00000171791.13	4386	0.520	0.1713	No
27	NFIL3	ENSG00000165030.4	4763	0.507	0.1692	No
28	ANKZF1	ENSG00000163516.14	4888	0.498	0.1732	No
29	PDK3	ENSG00000067992.15	4932	0.495	0.1792	No
30	FBP1	ENSG00000165140.10	5107	0.483	0.1817	No
31	CCN5	ENSG00000064205.10	5220	0.476	0.1857	No
32	CCNG2	ENSG00000138764.15	5991	0.434	0.1731	No
33	PNRC1	ENSG00000146278.11	6605	0.403	0.1638	No
34	ISG20	ENSG00000172183.15	6772	0.397	0.1653	No
35	EFNA3	ENSG00000143590.14	7095	0.385	0.1629	No
36	ACKR3	ENSG00000144476.6	7372	0.373	0.1614	No
37	BTG1	ENSG00000133639.5	7649	0.365	0.1599	No
38	PFKFB3	ENSG00000170525.21	8002	0.361	0.1564	No
39	SAP30	ENSG00000164105.4	8180	0.354	0.1570	No
40	BGN	ENSG00000182492.16	8477	0.352	0.1548	No
41	LDHC	ENSG00000166796.12	8497	0.351	0.1593	No
42	HMOX1	ENSG00000100292.17	9075	0.332	0.1499	No
43	PAM	ENSG00000145730.20	9186	0.328	0.1518	No
44	LALBA	ENSG00000167531.6	10237	0.305	0.1305	No
45	RORA	ENSG00000069667.16	10674	0.304	0.1241	No
46	PHKG1	ENSG00000164776.9	10960	0.292	0.1213	No
47	RBPJ	ENSG00000168214.20	11729	0.281	0.1065	No
48	GAPDHS	ENSG00000105679.9	11950	0.273	0.1050	No
49	PFKL	ENSG00000141959.17	11995	0.271	0.1077	No
50	BCAN	ENSG00000132692.19	12750	0.246	0.0928	No
51	ALDOC	ENSG00000109107.14	12846	0.243	0.0939	No
52	MAFF	ENSG00000185022.12	13047	0.236	0.0923	No
53	MIF	ENSG00000240972.2	13196	0.232	0.0920	No
54	FAM162A	ENSG00000114023.15	13232	0.231	0.0944	No
55	PPFIA4	ENSG00000143847.15	13557	0.220	0.0896	No
56	PPARGC1A	ENSG00000109819.9	13820	0.212	0.0862	No
57	LARGE1	ENSG00000133424.20	13853	0.211	0.0884	No
58	FOSL2	ENSG00000075426.12	13886	0.209	0.0906	No
59	SLC37A4	ENSG00000137700.18	13897	0.209	0.0933	No
60	CAVIN3	ENSG00000170955.10	13955	0.207	0.0948	No
61	IRS2	ENSG00000185950.9	14166	0.200	0.0925	No
62	ALDOB	ENSG00000136872.20	14273	0.198	0.0927	No
63	EDN2	ENSG00000127129.10	14507	0.190	0.0897	No
64	ILVBL	ENSG00000105135.16	14718	0.183	0.0872	No
65	AK4	ENSG00000162433.15	14736	0.183	0.0893	No
66	VEGFA	ENSG00000112715.22	15227	0.167	0.0797	No
67	STBD1	ENSG00000118804.8	15318	0.164	0.0799	No
68	SCARB1	ENSG00000073060.16	15471	0.160	0.0784	No
69	SELENBP1	ENSG00000143416.21	15624	0.156	0.0769	No
70	ZNF292	ENSG00000188994.13	15818	0.150	0.0743	No
71	PKLR	ENSG00000143627.19	16283	0.138	0.0649	No
72	KDM3A	ENSG00000115548.17	16641	0.127	0.0580	No
73	CSRP2	ENSG00000175183.10	16944	0.118	0.0523	No
74	FOXO3	ENSG00000118689.15	17017	0.117	0.0522	No
75	ZFP36	ENSG00000128016.7	17058	0.116	0.0528	No
76	SIAH2	ENSG00000181788.4	17816	0.096	0.0357	No
77	FOS	ENSG00000170345.10	17933	0.092	0.0342	No
78	CA12	ENSG00000074410.14	17955	0.092	0.0350	No
79	ENO3	ENSG00000108515.17	18133	0.087	0.0319	No
80	PIM1	ENSG00000137193.14	18349	0.082	0.0278	No
81	VHL	ENSG00000134086.7	18565	0.077	0.0236	No
82	GCNT2	ENSG00000111846.17	18915	0.068	0.0161	No
83	GAA	ENSG00000171298.13	19333	0.055	0.0067	No
84	NDRG1	ENSG00000104419.14	19578	0.049	0.0014	No
85	STC2	ENSG00000113739.10	19602	0.048	0.0015	No
86	SLC2A1	ENSG00000117394.23	19798	0.043	-0.0026	No
87	DCN	ENSG00000011465.17	20288	0.032	-0.0141	No
88	TGFB3	ENSG00000119699.7	20364	0.029	-0.0155	No
89	GRHPR	ENSG00000137106.18	21060	0.010	-0.0324	No
90	TIPARP	ENSG00000163659.13	21091	0.009	-0.0330	No
91	TMEM45A	ENSG00000181458.10	21199	0.007	-0.0355	No
92	CDKN1A	ENSG00000124762.13	21297	0.004	-0.0378	No
93	NAGK	ENSG00000124357.13	21364	0.002	-0.0394	No
94	DDIT3	ENSG00000175197.12	21390	0.001	-0.0400	No
95	HK2	ENSG00000159399.9	21414	0.001	-0.0405	No
96	WSB1	ENSG00000109046.15	21588	-0.004	-0.0447	No
97	DTNA	ENSG00000134769.21	21748	-0.008	-0.0485	No
98	SDC4	ENSG00000124145.6	21749	-0.008	-0.0484	No
99	PRKCA	ENSG00000154229.12	22219	-0.019	-0.0595	No
100	CCN2	ENSG00000118523.6	22253	-0.019	-0.0601	No
101	COL5A1	ENSG00000130635.15	22567	-0.028	-0.0673	No
102	KDELR3	ENSG00000100196.11	22740	-0.032	-0.0711	No
103	MT1E	ENSG00000169715.15	22802	-0.033	-0.0721	No
104	NDST2	ENSG00000166507.18	22990	-0.039	-0.0761	No
105	PLAC8	ENSG00000145287.10	23135	-0.043	-0.0790	No
106	VLDLR	ENSG00000147852.16	23181	-0.045	-0.0795	No
107	PKP1	ENSG00000081277.12	23458	-0.051	-0.0855	No
108	HEXA	ENSG00000213614.9	23544	-0.054	-0.0868	No
109	GLRX	ENSG00000173221.14	23563	-0.054	-0.0865	No
110	GPI	ENSG00000105220.17	23611	-0.056	-0.0869	No
111	GALK1	ENSG00000108479.12	23871	-0.062	-0.0923	No
112	GBE1	ENSG00000114480.13	23894	-0.063	-0.0920	No
113	SLC25A1	ENSG00000100075.10	23913	-0.064	-0.0915	No
114	EXT1	ENSG00000182197.11	24146	-0.068	-0.0962	No
115	ALDOA	ENSG00000149925.20	24530	-0.078	-0.1044	No
116	GCK	ENSG00000106633.17	25365	-0.101	-0.1234	No
117	BHLHE40	ENSG00000134107.5	25483	-0.105	-0.1248	No
118	LXN	ENSG00000079257.8	25642	-0.110	-0.1271	No
119	HAS1	ENSG00000105509.10	25668	-0.110	-0.1261	No
120	PYGM	ENSG00000068976.14	25795	-0.113	-0.1276	No
121	SULT2B1	ENSG00000088002.11	25907	-0.117	-0.1287	No
122	HS3ST1	ENSG00000002587.10	25942	-0.118	-0.1278	No
123	GAPDH	ENSG00000111640.15	26448	-0.134	-0.1383	No
124	GPC1	ENSG00000063660.9	26538	-0.136	-0.1385	No
125	IDS	ENSG00000010404.18	26695	-0.141	-0.1403	No
126	TPI1	ENSG00000111669.15	26955	-0.148	-0.1446	No
127	B3GALT6	ENSG00000176022.7	26956	-0.148	-0.1425	No
128	PPP1R15A	ENSG00000087074.8	27000	-0.149	-0.1414	No
129	TNFAIP3	ENSG00000118503.15	27043	-0.151	-0.1403	No
130	ATF3	ENSG00000162772.17	27076	-0.151	-0.1390	No
131	BNIP3L	ENSG00000104765.16	27191	-0.155	-0.1396	No
132	CASP6	ENSG00000138794.10	27327	-0.159	-0.1406	No
133	NCAN	ENSG00000130287.14	27413	-0.161	-0.1404	No
134	HDLBP	ENSG00000115677.17	27421	-0.162	-0.1383	No
135	CHST2	ENSG00000175040.6	27669	-0.170	-0.1419	No
136	MXI1	ENSG00000119950.21	28064	-0.183	-0.1490	No
137	IGFBP1	ENSG00000146678.10	28557	-0.198	-0.1582	No
138	ANGPTL4	ENSG00000167772.12	28905	-0.208	-0.1637	No
139	ATP7A	ENSG00000165240.20	28987	-0.212	-0.1627	No
140	SLC2A5	ENSG00000142583.18	29013	-0.212	-0.1603	No
141	PPP1R3C	ENSG00000119938.9	29469	-0.226	-0.1683	No
142	IL6	ENSG00000136244.12	29624	-0.231	-0.1687	No
143	PRDX5	ENSG00000126432.14	30144	-0.249	-0.1779	No
144	PLIN2	ENSG00000147872.10	30207	-0.250	-0.1759	No
145	CCN1	ENSG00000142871.17	30290	-0.253	-0.1743	No
146	PGM1	ENSG00000079739.17	30468	-0.259	-0.1750	No
147	XPNPEP1	ENSG00000108039.18	30817	-0.270	-0.1797	No
148	SRPX	ENSG00000101955.15	31035	-0.278	-0.1810	No
149	ETS1	ENSG00000134954.14	31835	-0.291	-0.1964	No
150	ERO1A	ENSG00000197930.13	31946	-0.294	-0.1950	No
151	HSPA5	ENSG00000044574.8	32282	-0.308	-0.1988	No
152	EGFR	ENSG00000146648.18	32910	-0.332	-0.2094	No
153	PGF	ENSG00000119630.14	34094	-0.345	-0.2334	No
154	JMJD6	ENSG00000070495.14	34612	-0.352	-0.2411	No
155	B4GALNT2	ENSG00000167080.8	35061	-0.368	-0.2468	No
156	PLAUR	ENSG00000011422.12	35312	-0.379	-0.2476	Yes
157	SDC3	ENSG00000162512.16	35439	-0.385	-0.2452	Yes
158	PFKP	ENSG00000067057.17	35494	-0.388	-0.2411	Yes
159	PDK1	ENSG00000152256.13	35589	-0.393	-0.2378	Yes
160	P4HA2	ENSG00000072682.18	35623	-0.395	-0.2331	Yes
161	ENO1	ENSG00000074800.16	35638	-0.395	-0.2278	Yes
162	PGM2	ENSG00000169299.14	35669	-0.396	-0.2230	Yes
163	PCK1	ENSG00000124253.11	35868	-0.402	-0.2221	Yes
164	ANXA2	ENSG00000182718.16	36074	-0.407	-0.2214	Yes
165	TKTL1	ENSG00000007350.17	36144	-0.411	-0.2173	Yes
166	ENO2	ENSG00000111674.9	36606	-0.431	-0.2224	Yes
167	CHST3	ENSG00000122863.6	36888	-0.445	-0.2230	Yes
168	CITED2	ENSG00000164442.10	37189	-0.463	-0.2238	Yes
169	P4HA1	ENSG00000122884.12	37364	-0.475	-0.2213	Yes
170	SERPINE1	ENSG00000106366.8	37533	-0.487	-0.2186	Yes
171	ERRFI1	ENSG00000116285.13	37565	-0.490	-0.2124	Yes
172	AKAP12	ENSG00000131016.17	37685	-0.501	-0.2082	Yes
173	PGK1	ENSG00000102144.15	37804	-0.512	-0.2039	Yes
174	TGFBI	ENSG00000120708.17	37818	-0.514	-0.1970	Yes
175	GYS1	ENSG00000104812.15	38103	-0.535	-0.1963	Yes
176	TPST2	ENSG00000128294.16	38137	-0.537	-0.1896	Yes
177	AMPD3	ENSG00000133805.15	38154	-0.539	-0.1824	Yes
178	SDC2	ENSG00000169439.12	38187	-0.541	-0.1755	Yes
179	NOCT	ENSG00000151014.6	38706	-0.571	-0.1801	Yes
180	KLF7	ENSG00000118263.15	38734	-0.574	-0.1726	Yes
181	HK1	ENSG00000156515.23	39440	-0.630	-0.1810	Yes
182	MYH9	ENSG00000100345.21	39531	-0.641	-0.1741	Yes
183	DUSP1	ENSG00000120129.6	39618	-0.648	-0.1671	Yes
184	ADORA2B	ENSG00000170425.3	39882	-0.692	-0.1637	Yes
185	HOXB9	ENSG00000170689.10	39931	-0.700	-0.1550	Yes
186	F3	ENSG00000117525.14	40005	-0.714	-0.1467	Yes
187	CAVIN1	ENSG00000177469.13	40101	-0.731	-0.1387	Yes
188	KLF6	ENSG00000067082.15	40162	-0.745	-0.1297	Yes
189	JUN	ENSG00000177606.7	40305	-0.779	-0.1222	Yes
190	ADM	ENSG00000148926.10	40523	-0.847	-0.1155	Yes
191	S100A4	ENSG00000196154.12	40530	-0.850	-0.1037	Yes
192	NDST1	ENSG00000070614.15	40535	-0.851	-0.0918	Yes
193	NR3C1	ENSG00000113580.15	40550	-0.857	-0.0800	Yes
194	SLC2A3	ENSG00000059804.16	40569	-0.866	-0.0682	Yes
195	LDHA	ENSG00000134333.14	40682	-0.914	-0.0581	Yes
196	UGP2	ENSG00000169764.15	40772	-0.945	-0.0469	Yes
197	TES	ENSG00000135269.18	40994	-1.130	-0.0364	Yes
198	CAV1	ENSG00000105974.12	41003	-1.149	-0.0204	Yes
199	LOX	ENSG00000113083.14	41130	-1.714	0.0008	Yes