Details for gene set HALLMARK_IL2_STAT5_SIGNALING[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_IL2_STAT5_SIGNALING
Enrichment Score (ES)	-0.22841942
Normalized Enrichment Score (NES)	-1.2217444
Nominal p-value	0.07482993
FDR q-value	0.14262362
FWER p-Value	0.811

Fig 1: Enrichment plot: HALLMARK_IL2_STAT5_SIGNALING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL13	ENSG00000169194.9			180	1.275	0.0119	No
2	TGM2	ENSG00000198959.12			237	1.183	0.0257	No
3	IL1R2	ENSG00000115590.14			280	1.147	0.0393	No
4	WLS	ENSG00000116729.14			435	1.042	0.0488	No
5	S100A1	ENSG00000160678.11			463	1.030	0.0614	No
6	RRAGD	ENSG00000025039.15			702	0.939	0.0675	No
7	BMP2	ENSG00000125845.7			710	0.936	0.0793	No
8	CISH	ENSG00000114737.15			726	0.933	0.0909	No
9	SLC39A8	ENSG00000138821.13			1070	0.844	0.0933	No
10	PENK	ENSG00000181195.11			1184	0.821	0.1010	No
11	IRF4	ENSG00000137265.15			1229	0.811	0.1103	No
12	CDKN1C	ENSG00000129757.13			1596	0.759	0.1111	No
13	LIF	ENSG00000128342.5			1603	0.758	0.1207	No
14	AHR	ENSG00000106546.14			1908	0.715	0.1224	No
15	PRKCH	ENSG00000027075.15			2159	0.687	0.1251	No
16	SMPDL3A	ENSG00000172594.13			2174	0.686	0.1335	No
17	IL2RB	ENSG00000100385.14			2208	0.683	0.1414	No
18	IFNGR1	ENSG00000027697.14			2329	0.669	0.1470	No
19	PTH1R	ENSG00000160801.14			2572	0.646	0.1494	No
20	MUC1	ENSG00000185499.16			2664	0.637	0.1553	No
21	PHLDA1	ENSG00000139289.13			2729	0.630	0.1618	No
22	BATF3	ENSG00000123685.9			3004	0.605	0.1628	No
23	RGS16	ENSG00000143333.7			3170	0.593	0.1664	No
24	LTB	ENSG00000227507.2			3397	0.576	0.1682	No
25	CDCP1	ENSG00000163814.8			3408	0.574	0.1753	No
26	CST7	ENSG00000077984.6			4293	0.524	0.1604	No
27	HOPX	ENSG00000171476.22			4310	0.523	0.1667	No
28	BCL2	ENSG00000171791.13			4386	0.520	0.1715	No
29	NFIL3	ENSG00000165030.4			4763	0.507	0.1688	No
30	CCND2	ENSG00000118971.8			4862	0.500	0.1728	No
31	CD44	ENSG00000026508.18			4934	0.495	0.1774	No
32	NOP2	ENSG00000111641.11			4949	0.494	0.1834	No
33	SOCS2	ENSG00000120833.14			5140	0.481	0.1849	No
34	AGER	ENSG00000204305.14			5212	0.477	0.1893	No
35	SLC29A2	ENSG00000174669.12			5384	0.466	0.1911	No
36	SCN9A	ENSG00000169432.16			5398	0.465	0.1967	No
37	TNFRSF18	ENSG00000186891.14			5531	0.458	0.1993	No
38	F2RL2	ENSG00000164220.7			5734	0.446	0.2001	No
39	PLAGL1	ENSG00000118495.19			5858	0.441	0.2027	No
40	COCH	ENSG00000100473.18			6222	0.421	0.1993	No
41	TNFSF10	ENSG00000121858.11			6380	0.413	0.2007	No
42	FAH	ENSG00000103876.12			6411	0.412	0.2052	No
43	SNX9	ENSG00000130340.16			6548	0.406	0.2071	No
44	PTGER2	ENSG00000125384.7			6983	0.390	0.2015	No
45	IL18R1	ENSG00000115604.10			7316	0.376	0.1982	No
46	ENPP1	ENSG00000197594.13			7476	0.372	0.1991	No
47	GLIPR2	ENSG00000122694.16			8105	0.357	0.1883	No
48	POU2F1	ENSG00000143190.23			8203	0.353	0.1905	No
49	IL4R	ENSG00000077238.14			8901	0.339	0.1778	No
50	SERPINC1	ENSG00000117601.13			8910	0.339	0.1819	No
51	PRAF2	ENSG00000243279.4			8931	0.338	0.1858	No
52	APLP1	ENSG00000105290.12			9232	0.326	0.1826	No
53	IGF1R	ENSG00000140443.15			9322	0.322	0.1845	No
54	RHOH	ENSG00000168421.13			9330	0.322	0.1885	No
55	CAPN3	ENSG00000092529.24			9932	0.314	0.1778	No
56	RORA	ENSG00000069667.16			10674	0.304	0.1636	No
57	MXD1	ENSG00000059728.11			10676	0.304	0.1675	No
58	ETV4	ENSG00000175832.13			11684	0.283	0.1465	No
59	PLSCR1	ENSG00000188313.13			12014	0.270	0.1419	No
60	SH3BGRL2	ENSG00000198478.8			12246	0.263	0.1397	No
61	GABARAPL1	ENSG00000139112.11			12462	0.255	0.1377	No
62	CA2	ENSG00000104267.10			12533	0.253	0.1392	No
63	TNFRSF21	ENSG00000146072.6			12662	0.249	0.1393	No
64	CD81	ENSG00000110651.11			12744	0.247	0.1404	No
65	MAFF	ENSG00000185022.12			13047	0.236	0.1361	No
66	P2RX4	ENSG00000135124.14			13164	0.233	0.1362	No
67	GATA1	ENSG00000102145.14			13724	0.215	0.1253	No
68	GPR65	ENSG00000140030.6			14045	0.204	0.1201	No
69	DRC1	ENSG00000157856.12			14091	0.203	0.1216	No
70	ABCB1	ENSG00000085563.14			14109	0.202	0.1238	No
71	PTCH1	ENSG00000185920.15			14439	0.193	0.1182	No
72	IGF2R	ENSG00000197081.14			14615	0.187	0.1163	No
73	CCR4	ENSG00000183813.7			14891	0.177	0.1119	No
74	GPX4	ENSG00000167468.17			15215	0.168	0.1062	No
75	UMPS	ENSG00000114491.14			15817	0.150	0.0934	No
76	CD83	ENSG00000112149.10			15825	0.150	0.0951	No
77	IL2RA	ENSG00000134460.17			15953	0.146	0.0939	No
78	TRAF1	ENSG00000056558.11			16131	0.142	0.0914	No
79	TTC39B	ENSG00000155158.20			16319	0.137	0.0886	No
80	RHOB	ENSG00000143878.10			16535	0.130	0.0850	No
81	SYNGR2	ENSG00000108639.7			16740	0.124	0.0816	No
82	IFITM3	ENSG00000142089.16			17463	0.105	0.0653	No
83	CSF1	ENSG00000184371.14			17952	0.092	0.0546	No
84	PDCD2L	ENSG00000126249.8			18009	0.090	0.0544	No
85	ENO3	ENSG00000108515.17			18133	0.087	0.0525	No
86	PUS1	ENSG00000177192.14			18161	0.087	0.0529	No
87	COL6A1	ENSG00000142156.14			18165	0.087	0.0540	No
88	IKZF4	ENSG00000123411.15			18307	0.084	0.0516	No
89	PIM1	ENSG00000137193.14			18349	0.082	0.0516	No
90	IKZF2	ENSG00000030419.16			18729	0.073	0.0433	No
91	ST3GAL4	ENSG00000110080.18			18736	0.072	0.0441	No
92	EOMES	ENSG00000163508.13			18998	0.065	0.0386	No
93	MYO1E	ENSG00000157483.9			19330	0.055	0.0312	No
94	NFKBIZ	ENSG00000144802.11			19416	0.053	0.0298	No
95	NDRG1	ENSG00000104419.14			19578	0.049	0.0265	No
96	MAP3K8	ENSG00000107968.10			19857	0.042	0.0202	No
97	TIAM1	ENSG00000156299.13			20475	0.025	0.0055	No
98	SPRY4	ENSG00000187678.9			20655	0.021	0.0014	No
99	MAPKAPK2	ENSG00000162889.10			20713	0.019	0.0003	No
100	ETFBKMT	ENSG00000139160.13			20732	0.019	0.0001	No
101	HK2	ENSG00000159399.9			21414	0.001	-0.0166	No
102	AMACR	ENSG00000242110.8			21907	-0.012	-0.0284	No
103	CD79B	ENSG00000007312.12			22164	-0.017	-0.0344	No
104	IRF6	ENSG00000117595.12			22754	-0.032	-0.0484	No
105	GUCY1B1	ENSG00000061918.13			22867	-0.035	-0.0507	No
106	XBP1	ENSG00000100219.16			22900	-0.036	-0.0510	No
107	ALCAM	ENSG00000170017.12			22924	-0.037	-0.0511	No
108	FAM126B	ENSG00000155744.9			23709	-0.058	-0.0695	No
109	NT5E	ENSG00000135318.12			24453	-0.076	-0.0867	No
110	DHRS3	ENSG00000162496.9			24804	-0.086	-0.0941	No
111	SELL	ENSG00000188404.10			24840	-0.087	-0.0939	No
112	ITGAE	ENSG00000083457.12			25206	-0.096	-0.1015	No
113	BHLHE40	ENSG00000134107.5			25483	-0.105	-0.1069	No
114	GPR83	ENSG00000123901.9			25578	-0.107	-0.1079	No
115	TLR7	ENSG00000196664.5			25886	-0.117	-0.1139	No
116	SYT11	ENSG00000132718.9			26204	-0.126	-0.1200	No
117	TWSG1	ENSG00000128791.12			26343	-0.130	-0.1217	No
118	FURIN	ENSG00000140564.12			26542	-0.136	-0.1248	No
119	SOCS1	ENSG00000185338.5			26705	-0.141	-0.1269	No
120	SERPINB6	ENSG00000124570.20			26707	-0.141	-0.1252	No
121	HUWE1	ENSG00000086758.16			27995	-0.180	-0.1543	No
122	SLC1A5	ENSG00000105281.12			28017	-0.181	-0.1525	No
123	TNFRSF1B	ENSG00000028137.19			28280	-0.189	-0.1565	No
124	DCPS	ENSG00000110063.10			28326	-0.190	-0.1551	No
125	PRNP	ENSG00000171867.17			28702	-0.202	-0.1617	No
126	EEF1AKMT1	ENSG00000150456.11			28797	-0.205	-0.1614	No
127	SNX14	ENSG00000135317.13			29130	-0.216	-0.1667	No
128	RNH1	ENSG00000023191.17			29292	-0.221	-0.1678	No
129	ITIH5	ENSG00000123243.15			29842	-0.239	-0.1782	No
130	FLT3LG	ENSG00000090554.13			30091	-0.247	-0.1811	No
131	PLIN2	ENSG00000147872.10			30207	-0.250	-0.1807	No
132	CKAP4	ENSG00000136026.14			30989	-0.277	-0.1962	No
133	PTRH2	ENSG00000141378.14			31046	-0.279	-0.1940	No
134	CTSZ	ENSG00000101160.14			31105	-0.281	-0.1918	No
135	CYFIP1	ENSG00000273749.5			31788	-0.289	-0.2048	No
136	CCNE1	ENSG00000105173.14			32197	-0.305	-0.2108	No
137	TNFRSF4	ENSG00000186827.11			32325	-0.310	-0.2100	No
138	AHNAK	ENSG00000124942.14			32497	-0.317	-0.2101	No
139	SHE	ENSG00000169291.10			32504	-0.317	-0.2062	No
140	MYO1C	ENSG00000197879.17			32509	-0.317	-0.2023	No
141	CCND3	ENSG00000112576.12			32532	-0.317	-0.1987	No
142	FGL2	ENSG00000127951.7			32655	-0.323	-0.1976	No
143	CTLA4	ENSG00000163599.17			32687	-0.324	-0.1942	No
144	CXCL10	ENSG00000169245.6			32700	-0.324	-0.1904	No
145	CAPG	ENSG00000042493.16			32769	-0.326	-0.1879	No
146	ODC1	ENSG00000115758.13			32958	-0.334	-0.1882	No
147	TNFSF11	ENSG00000120659.15			33152	-0.336	-0.1886	No
148	SPRED2	ENSG00000198369.10			34671	-0.355	-0.2211	No
149	GALM	ENSG00000143891.17			34972	-0.364	-0.2238	Yes
150	ADAM19	ENSG00000135074.15			35096	-0.368	-0.2221	Yes
151	AHCY	ENSG00000101444.13			35184	-0.373	-0.2194	Yes
152	CASP3	ENSG00000164305.19			35329	-0.380	-0.2181	Yes
153	IL1RL1	ENSG00000115602.17			35484	-0.388	-0.2169	Yes
154	RABGAP1L	ENSG00000152061.23			35578	-0.393	-0.2141	Yes
155	GSTO1	ENSG00000148834.13			35765	-0.400	-0.2136	Yes
156	CD86	ENSG00000114013.16			35887	-0.402	-0.2114	Yes
157	PNP	ENSG00000198805.11			36135	-0.411	-0.2121	Yes
158	LCLAT1	ENSG00000172954.13			36670	-0.434	-0.2196	Yes
159	EMP1	ENSG00000134531.10			36872	-0.444	-0.2189	Yes
160	GBP4	ENSG00000162654.9			37113	-0.458	-0.2189	Yes
161	LRIG1	ENSG00000144749.13			37286	-0.470	-0.2171	Yes
162	PLPP1	ENSG00000067113.17			37340	-0.474	-0.2123	Yes
163	BMPR2	ENSG00000204217.15			37352	-0.475	-0.2065	Yes
164	P4HA1	ENSG00000122884.12			37364	-0.475	-0.2007	Yes
165	HIPK2	ENSG00000064393.16			37609	-0.494	-0.2003	Yes
166	PLEC	ENSG00000178209.15			37624	-0.496	-0.1943	Yes
167	ITGAV	ENSG00000138448.12			37784	-0.511	-0.1917	Yes
168	BATF	ENSG00000156127.7			38174	-0.540	-0.1943	Yes
169	CSF2	ENSG00000164400.6			38203	-0.543	-0.1880	Yes
170	TNFRSF8	ENSG00000120949.15			38537	-0.560	-0.1890	Yes
171	BCL2L1	ENSG00000171552.13			38679	-0.568	-0.1852	Yes
172	ANXA4	ENSG00000196975.16			38680	-0.569	-0.1779	Yes
173	SPP1	ENSG00000118785.14			38686	-0.569	-0.1707	Yes
174	LRRC8C	ENSG00000171488.15			38900	-0.590	-0.1684	Yes
175	MYC	ENSG00000136997.19			39003	-0.602	-0.1632	Yes
176	DENND5A	ENSG00000184014.8			39087	-0.611	-0.1574	Yes
177	SELP	ENSG00000174175.17			39143	-0.614	-0.1509	Yes
178	CDC42SE2	ENSG00000158985.13			39311	-0.624	-0.1470	Yes
179	ECM1	ENSG00000143369.15			39921	-0.699	-0.1530	Yes
180	GADD45B	ENSG00000099860.9			40019	-0.716	-0.1462	Yes
181	ARL4A	ENSG00000122644.13			40051	-0.722	-0.1377	Yes
182	CDC6	ENSG00000094804.12			40060	-0.723	-0.1287	Yes
183	KLF6	ENSG00000067082.15			40162	-0.745	-0.1216	Yes
184	NCS1	ENSG00000107130.10			40188	-0.750	-0.1126	Yes
185	MAP6	ENSG00000171533.11			40217	-0.756	-0.1036	Yes
186	PHTF2	ENSG00000006576.16			40375	-0.798	-0.0973	Yes
187	NRP1	ENSG00000099250.18			40541	-0.854	-0.0904	Yes
188	SLC2A3	ENSG00000059804.16			40569	-0.866	-0.0800	Yes
189	IL10RA	ENSG00000110324.10			40784	-0.953	-0.0730	Yes
190	UCK2	ENSG00000143179.16			40869	-1.012	-0.0621	Yes
191	SWAP70	ENSG00000133789.15			40989	-1.124	-0.0507	Yes
192	NCOA3	ENSG00000124151.19			41048	-1.221	-0.0365	Yes
193	ITGA6	ENSG00000091409.15			41076	-1.311	-0.0204	Yes
194	TNFRSF9	ENSG00000049249.8			41133	-1.755	0.0007	Yes

Fig 2: HALLMARK_IL2_STAT5_SIGNALING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_IL2_STAT5_SIGNALING: Random ES distribution   
Gene set null distribution of ES for HALLMARK_IL2_STAT5_SIGNALING