Details for gene set HALLMARK_INFLAMMATORY_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_INFLAMMATORY_RESPONSE
Enrichment Score (ES)	0.24734537
Normalized Enrichment Score (NES)	1.189314
Nominal p-value	0.12219101
FDR q-value	0.20496924
FWER p-Value	0.997

Fig 1: Enrichment plot: HALLMARK_INFLAMMATORY_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCRL2	ENSG00000121797.10			4	2.444	0.0305	Yes
2	NLRP3	ENSG00000162711.17			20	1.857	0.0533	Yes
3	HPN	ENSG00000105707.14			162	1.301	0.0662	Yes
4	P2RX7	ENSG00000089041.17			265	1.162	0.0782	Yes
5	TIMP1	ENSG00000102265.12			352	1.090	0.0898	Yes
6	SLC7A2	ENSG00000003989.17			597	0.979	0.0961	Yes
7	GABBR1	ENSG00000204681.11			700	0.941	0.1053	Yes
8	IFITM1	ENSG00000185885.16			785	0.916	0.1147	Yes
9	IRF7	ENSG00000185507.21			812	0.910	0.1255	Yes
10	CCR7	ENSG00000126353.3			1153	0.825	0.1275	Yes
11	GPC3	ENSG00000147257.14			1281	0.805	0.1345	Yes
12	IL1R1	ENSG00000115594.12			1321	0.799	0.1435	Yes
13	TLR2	ENSG00000137462.8			1599	0.759	0.1463	Yes
14	LIF	ENSG00000128342.5			1603	0.758	0.1557	Yes
15	LPAR1	ENSG00000198121.13			1657	0.752	0.1638	Yes
16	CCL7	ENSG00000108688.11			1881	0.720	0.1673	Yes
17	AHR	ENSG00000106546.14			1908	0.715	0.1757	Yes
18	CX3CL1	ENSG00000006210.7			1988	0.707	0.1826	Yes
19	TACR1	ENSG00000115353.11			2141	0.689	0.1875	Yes
20	IL2RB	ENSG00000100385.14			2208	0.683	0.1944	Yes
21	PTGER4	ENSG00000171522.6			2872	0.616	0.1859	Yes
22	CXCL6	ENSG00000124875.10			2918	0.612	0.1925	Yes
23	BTG2	ENSG00000159388.6			2993	0.606	0.1983	Yes
24	RGS16	ENSG00000143333.7			3170	0.593	0.2014	Yes
25	RTP4	ENSG00000136514.3			3190	0.592	0.2083	Yes
26	TPBG	ENSG00000146242.8			3275	0.586	0.2136	Yes
27	IL1B	ENSG00000125538.12			3430	0.572	0.2170	Yes
28	PDPN	ENSG00000162493.16			3690	0.558	0.2177	Yes
29	PDE4B	ENSG00000184588.18			4101	0.537	0.2144	Yes
30	IL1A	ENSG00000115008.5			4274	0.526	0.2168	Yes
31	LCP2	ENSG00000043462.12			4413	0.519	0.2199	Yes
32	GPR132	ENSG00000183484.12			4540	0.516	0.2233	Yes
33	CCL17	ENSG00000102970.11			4670	0.512	0.2265	Yes
34	ABCA1	ENSG00000165029.16			4697	0.511	0.2323	Yes
35	IL12B	ENSG00000113302.4			5068	0.486	0.2293	Yes
36	SEMA4D	ENSG00000187764.11			5211	0.477	0.2318	Yes
37	KCNA3	ENSG00000177272.9			5262	0.474	0.2365	Yes
38	NAMPT	ENSG00000105835.12			5278	0.473	0.2421	Yes
39	IL18RAP	ENSG00000115607.9			5756	0.445	0.2360	Yes
40	GCH1	ENSG00000131979.19			6236	0.421	0.2296	Yes
41	TNFSF10	ENSG00000121858.11			6380	0.413	0.2313	Yes
42	TLR1	ENSG00000174125.8			6430	0.410	0.2352	Yes
43	LDLR	ENSG00000130164.13			6959	0.391	0.2272	Yes
44	PTGER2	ENSG00000125384.7			6983	0.390	0.2315	Yes
45	RASGRP1	ENSG00000172575.12			7013	0.389	0.2357	Yes
46	CMKLR1	ENSG00000174600.14			7266	0.377	0.2342	Yes
47	IL18R1	ENSG00000115604.10			7316	0.376	0.2377	Yes
48	GP1BA	ENSG00000185245.8			7362	0.374	0.2413	Yes
49	CYBB	ENSG00000165168.7			7450	0.372	0.2439	Yes
50	LTA	ENSG00000226979.8			8046	0.359	0.2338	Yes
51	P2RY2	ENSG00000175591.11			8099	0.358	0.2370	Yes
52	SCARF1	ENSG00000074660.16			8123	0.357	0.2409	Yes
53	SLC1A2	ENSG00000110436.13			8193	0.354	0.2437	Yes
54	CSF3R	ENSG00000119535.17			8224	0.352	0.2473	Yes
55	IL4R	ENSG00000077238.14			8901	0.339	0.2351	No
56	IRF1	ENSG00000125347.14			9828	0.318	0.2165	No
57	CCL5	ENSG00000271503.6			9843	0.317	0.2201	No
58	TACR3	ENSG00000169836.5			9919	0.315	0.2222	No
59	ICAM1	ENSG00000090339.9			9924	0.314	0.2260	No
60	NPFFR2	ENSG00000056291.17			10245	0.305	0.2220	No
61	ICOSLG	ENSG00000160223.17			10654	0.304	0.2159	No
62	MXD1	ENSG00000059728.11			10676	0.304	0.2192	No
63	CD82	ENSG00000085117.12			11688	0.283	0.1980	No
64	C5AR1	ENSG00000197405.8			11756	0.280	0.1999	No
65	LCK	ENSG00000182866.17			11848	0.276	0.2011	No
66	LY6E	ENSG00000160932.11			12542	0.253	0.1874	No
67	MMP14	ENSG00000157227.13			12590	0.252	0.1894	No
68	APLNR	ENSG00000134817.10			12714	0.247	0.1895	No
69	IL15RA	ENSG00000134470.21			12907	0.241	0.1878	No
70	STAB1	ENSG00000010327.10			13026	0.237	0.1879	No
71	P2RX4	ENSG00000135124.14			13164	0.233	0.1875	No
72	CCL24	ENSG00000106178.6			13280	0.229	0.1875	No
73	MEFV	ENSG00000103313.12			13403	0.225	0.1874	No
74	ACVR1B	ENSG00000135503.13			13757	0.214	0.1814	No
75	CD40	ENSG00000101017.14			13803	0.213	0.1830	No
76	TNFAIP6	ENSG00000123610.5			14070	0.204	0.1790	No
77	EBI3	ENSG00000105246.6			14531	0.189	0.1702	No
78	OPRK1	ENSG00000082556.12			14604	0.187	0.1708	No
79	CCL2	ENSG00000108691.9			14738	0.183	0.1698	No
80	LAMP3	ENSG00000078081.8			14900	0.177	0.1681	No
81	CXCL9	ENSG00000138755.6			16417	0.133	0.1328	No
82	IFNGR2	ENSG00000159128.14			16912	0.119	0.1222	No
83	ROS1	ENSG00000047936.10			17114	0.114	0.1187	No
84	ATP2B1	ENSG00000070961.15			17717	0.099	0.1052	No
85	CSF1	ENSG00000184371.14			17952	0.092	0.1007	No
86	CXCR6	ENSG00000172215.6			18020	0.090	0.1002	No
87	OSMR	ENSG00000145623.13			18084	0.088	0.0997	No
88	LYN	ENSG00000254087.8			18130	0.087	0.0997	No
89	ADRM1	ENSG00000130706.13			18532	0.078	0.0909	No
90	TLR3	ENSG00000164342.12			19180	0.060	0.0759	No
91	NFKB1	ENSG00000109320.13			19218	0.059	0.0757	No
92	ITGB3	ENSG00000259207.7			19335	0.055	0.0736	No
93	CCL20	ENSG00000115009.13			20079	0.037	0.0559	No
94	FZD5	ENSG00000163251.4			20082	0.037	0.0563	No
95	GNA15	ENSG00000060558.4			20226	0.033	0.0532	No
96	EREG	ENSG00000124882.4			20508	0.024	0.0467	No
97	CXCL11	ENSG00000169248.13			20828	0.017	0.0391	No
98	PTAFR	ENSG00000169403.12			20842	0.016	0.0390	No
99	KCNJ2	ENSG00000123700.4			20935	0.014	0.0369	No
100	RIPK2	ENSG00000104312.8			21192	0.007	0.0308	No
101	CDKN1A	ENSG00000124762.13			21297	0.004	0.0283	No
102	CALCRL	ENSG00000064989.13			21590	-0.004	0.0212	No
103	CD55	ENSG00000196352.15			21778	-0.009	0.0167	No
104	PROK2	ENSG00000163421.9			21882	-0.011	0.0144	No
105	SCN1B	ENSG00000105711.12			22218	-0.018	0.0064	No
106	EIF2AK2	ENSG00000055332.18			22459	-0.025	0.0009	No
107	ATP2A2	ENSG00000174437.17			22480	-0.026	0.0007	No
108	NFKBIA	ENSG00000100906.10			22848	-0.035	-0.0078	No
109	RELA	ENSG00000173039.19			23632	-0.056	-0.0262	No
110	RGS1	ENSG00000090104.12			23939	-0.064	-0.0329	No
111	SRI	ENSG00000075142.13			24123	-0.067	-0.0365	No
112	BEST1	ENSG00000167995.16			24168	-0.069	-0.0367	No
113	IFNAR1	ENSG00000142166.13			24251	-0.072	-0.0378	No
114	PSEN1	ENSG00000080815.19			24443	-0.076	-0.0415	No
115	SELL	ENSG00000188404.10			24840	-0.087	-0.0501	No
116	OSM	ENSG00000099985.4			25211	-0.096	-0.0580	No
117	ACVR2A	ENSG00000121989.15			25237	-0.097	-0.0573	No
118	GPR183	ENSG00000169508.7			25743	-0.112	-0.0683	No
119	SGMS2	ENSG00000164023.14			26053	-0.122	-0.0743	No
120	BST2	ENSG00000130303.13			26105	-0.124	-0.0740	No
121	PCDH7	ENSG00000169851.15			26172	-0.125	-0.0740	No
122	AQP9	ENSG00000103569.10			26201	-0.126	-0.0731	No
123	TAPBP	ENSG00000231925.11			26413	-0.133	-0.0766	No
124	PVR	ENSG00000073008.15			26458	-0.134	-0.0760	No
125	IL18	ENSG00000150782.12			26822	-0.144	-0.0831	No
126	RHOG	ENSG00000177105.10			26871	-0.145	-0.0824	No
127	NOD2	ENSG00000167207.13			26987	-0.149	-0.0834	No
128	NMI	ENSG00000123609.11			27198	-0.155	-0.0866	No
129	CHST2	ENSG00000175040.6			27669	-0.170	-0.0959	No
130	SELENOS	ENSG00000131871.15			28063	-0.183	-0.1032	No
131	TNFRSF1B	ENSG00000028137.19			28280	-0.189	-0.1061	No
132	SLC31A1	ENSG00000136868.11			28289	-0.189	-0.1040	No
133	CSF3	ENSG00000108342.12			28399	-0.193	-0.1042	No
134	MSR1	ENSG00000038945.15			28595	-0.199	-0.1065	No
135	PTPRE	ENSG00000132334.16			28934	-0.210	-0.1121	No
136	HIF1A	ENSG00000100644.17			29230	-0.218	-0.1166	No
137	IL6	ENSG00000136244.12			29624	-0.231	-0.1233	No
138	MARCO	ENSG00000019169.10			29725	-0.235	-0.1228	No
139	ITGB8	ENSG00000105855.10			30265	-0.253	-0.1328	No
140	SLC11A2	ENSG00000110911.16			30597	-0.262	-0.1376	No
141	EMP3	ENSG00000142227.11			30646	-0.264	-0.1354	No
142	RAF1	ENSG00000132155.11			30802	-0.270	-0.1359	No
143	AXL	ENSG00000167601.12			31198	-0.285	-0.1419	No
144	CCL22	ENSG00000102962.5			31587	-0.285	-0.1478	No
145	KCNMB2	ENSG00000197584.12			31955	-0.295	-0.1531	No
146	NDP	ENSG00000124479.11			32120	-0.301	-0.1533	No
147	SLC28A2	ENSG00000137860.12			32233	-0.306	-0.1522	No
148	GNAI3	ENSG00000065135.11			32448	-0.315	-0.1535	No
149	CXCL10	ENSG00000169245.6			32700	-0.324	-0.1556	No
150	IRAK2	ENSG00000134070.5			32907	-0.332	-0.1565	No
151	VIP	ENSG00000146469.13			33186	-0.336	-0.1590	No
152	HRH1	ENSG00000196639.6			33562	-0.338	-0.1640	No
153	BDKRB1	ENSG00000100739.11			33570	-0.339	-0.1599	No
154	CD14	ENSG00000170458.14			34097	-0.345	-0.1684	No
155	PIK3R5	ENSG00000141506.13			34205	-0.350	-0.1667	No
156	C3AR1	ENSG00000171860.5			34621	-0.353	-0.1724	No
157	KIF1B	ENSG00000054523.17			34654	-0.354	-0.1687	No
158	NMUR1	ENSG00000171596.7			35208	-0.374	-0.1775	No
159	PLAUR	ENSG00000011422.12			35312	-0.379	-0.1753	No
160	RNF144B	ENSG00000137393.9			35421	-0.385	-0.1731	No
161	ATP2C1	ENSG00000017260.19			35680	-0.397	-0.1745	No
162	SPHK1	ENSG00000176170.13			35713	-0.398	-0.1703	No
163	FPR1	ENSG00000171051.8			36312	-0.416	-0.1797	No
164	ABI1	ENSG00000136754.17			36378	-0.420	-0.1760	No
165	ITGA5	ENSG00000161638.11			36500	-0.427	-0.1736	No
166	INHBA	ENSG00000122641.11			36833	-0.442	-0.1762	No
167	TNFSF15	ENSG00000181634.8			36930	-0.448	-0.1729	No
168	PTGIR	ENSG00000160013.9			37306	-0.471	-0.1762	No
169	SERPINE1	ENSG00000106366.8			37533	-0.487	-0.1756	No
170	TNFSF9	ENSG00000125657.5			37744	-0.507	-0.1744	No
171	HBEGF	ENSG00000113070.8			38438	-0.558	-0.1843	No
172	IL7R	ENSG00000168685.15			38829	-0.583	-0.1866	No
173	MYC	ENSG00000136997.19			39003	-0.602	-0.1833	No
174	OLR1	ENSG00000173391.9			39260	-0.619	-0.1818	No
175	MET	ENSG00000105976.15			39317	-0.624	-0.1753	No
176	SLC7A1	ENSG00000139514.13			39608	-0.647	-0.1743	No
177	EDN1	ENSG00000078401.7			39866	-0.688	-0.1720	No
178	ADORA2B	ENSG00000170425.3			39882	-0.692	-0.1637	No
179	F3	ENSG00000117525.14			40005	-0.714	-0.1577	No
180	CXCL8	ENSG00000169429.11			40055	-0.722	-0.1499	No
181	CD70	ENSG00000125726.11			40070	-0.726	-0.1411	No
182	KLF6	ENSG00000067082.15			40162	-0.745	-0.1340	No
183	SLC31A2	ENSG00000136867.11			40458	-0.827	-0.1309	No
184	ADM	ENSG00000148926.10			40523	-0.847	-0.1219	No
185	DCBLD2	ENSG00000057019.16			40653	-0.900	-0.1138	No
186	MEP1A	ENSG00000112818.10			40712	-0.927	-0.1036	No
187	IL10RA	ENSG00000110324.10			40784	-0.953	-0.0934	No
188	SLC4A4	ENSG00000080493.17			40795	-0.961	-0.0816	No
189	IL15	ENSG00000164136.17			41012	-1.156	-0.0724	No
190	CD69	ENSG00000110848.8			41040	-1.206	-0.0580	No
191	HAS2	ENSG00000170961.7			41046	-1.217	-0.0429	No
192	TNFRSF9	ENSG00000049249.8			41133	-1.755	-0.0230	No
193	ADGRE1	ENSG00000174837.15			41139	-1.894	0.0005	No

Fig 2: HALLMARK_INFLAMMATORY_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INFLAMMATORY_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INFLAMMATORY_RESPONSE