Details for gene set HALLMARK_INTERFERON_ALPHA_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_INTERFERON_ALPHA_RESPONSE
Enrichment Score (ES)	0.3497709
Normalized Enrichment Score (NES)	1.5247353
Nominal p-value	0.010233918
FDR q-value	0.042142518
FWER p-Value	0.247

Fig 1: Enrichment plot: HALLMARK_INTERFERON_ALPHA_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCRL2	ENSG00000121797.10			4	2.444	0.0794	Yes
2	RNF31	ENSG00000092098.17			528	1.004	0.0993	Yes
3	IFITM1	ENSG00000185885.16			785	0.916	0.1228	Yes
4	IRF7	ENSG00000185507.21			812	0.910	0.1518	Yes
5	IFI44L	ENSG00000137959.16			1186	0.820	0.1694	Yes
6	C1S	ENSG00000182326.15			1233	0.811	0.1947	Yes
7	OASL	ENSG00000135114.12			1975	0.708	0.1996	Yes
8	NCOA7	ENSG00000111912.20			2392	0.663	0.2111	Yes
9	MX1	ENSG00000157601.14			2878	0.616	0.2193	Yes
10	RTP4	ENSG00000136514.3			3190	0.592	0.2310	Yes
11	RSAD2	ENSG00000134321.12			3652	0.561	0.2380	Yes
12	USP18	ENSG00000184979.10			3745	0.554	0.2538	Yes
13	IFIH1	ENSG00000115267.8			3962	0.542	0.2661	Yes
14	HELZ2	ENSG00000130589.16			4036	0.539	0.2819	Yes
15	IRF9	ENSG00000213928.9			5089	0.484	0.2720	Yes
16	CMPK2	ENSG00000134326.11			5565	0.456	0.2752	Yes
17	EPSTI1	ENSG00000133106.14			6091	0.429	0.2764	Yes
18	DDX60	ENSG00000137628.17			6234	0.421	0.2866	Yes
19	HERC6	ENSG00000138642.14			6720	0.400	0.2878	Yes
20	ISG20	ENSG00000172183.15			6772	0.397	0.2995	Yes
21	AC004551.1	ENSG00000257452.1			6840	0.394	0.3107	Yes
22	DHX58	ENSG00000108771.13			7021	0.388	0.3189	Yes
23	IL4R	ENSG00000077238.14			8901	0.339	0.2842	Yes
24	IFI27	ENSG00000165949.12			8989	0.336	0.2930	Yes
25	ISG15	ENSG00000187608.10			9081	0.332	0.3016	Yes
26	GBP2	ENSG00000162645.13			9197	0.327	0.3094	Yes
27	TAP1	ENSG00000168394.11			9314	0.323	0.3171	Yes
28	IRF1	ENSG00000125347.14			9828	0.318	0.3149	Yes
29	UBA7	ENSG00000182179.13			9959	0.313	0.3219	Yes
30	CD74	ENSG00000019582.15			9998	0.311	0.3311	Yes
31	PARP14	ENSG00000173193.15			10063	0.309	0.3396	Yes
32	UBE2L6	ENSG00000156587.16			11121	0.287	0.3232	Yes
33	IFI35	ENSG00000068079.7			11935	0.274	0.3123	Yes
34	PLSCR1	ENSG00000188313.13			12014	0.270	0.3192	Yes
35	PARP12	ENSG00000059378.12			12149	0.266	0.3246	Yes
36	LPAR6	ENSG00000139679.15			12262	0.262	0.3304	Yes
37	LY6E	ENSG00000160932.11			12542	0.253	0.3318	Yes
38	BATF2	ENSG00000168062.10			12564	0.253	0.3395	Yes
39	MOV10	ENSG00000155363.18			12719	0.247	0.3438	Yes
40	IFI44	ENSG00000137965.11			12802	0.244	0.3498	Yes
41	STAT2	ENSG00000170581.14			13299	0.229	0.3451	No
42	PSMB8	ENSG00000204264.11			14058	0.204	0.3333	No
43	TRIM21	ENSG00000132109.10			14145	0.201	0.3377	No
44	LAMP3	ENSG00000078081.8			14900	0.177	0.3251	No
45	OGFR	ENSG00000060491.16			15086	0.171	0.3262	No
46	CASP1	ENSG00000137752.24			15477	0.160	0.3219	No
47	SAMD9	ENSG00000205413.8			16097	0.143	0.3114	No
48	IFIT3	ENSG00000119917.14			16281	0.138	0.3115	No
49	PARP9	ENSG00000138496.16			16312	0.137	0.3152	No
50	IL7	ENSG00000104432.14			16729	0.124	0.3091	No
51	ADAR	ENSG00000160710.17			16918	0.119	0.3084	No
52	TMEM140	ENSG00000146859.6			17411	0.107	0.2999	No
53	IFITM3	ENSG00000142089.16			17463	0.105	0.3020	No
54	GMPR	ENSG00000137198.10			17800	0.096	0.2970	No
55	CSF1	ENSG00000184371.14			17952	0.092	0.2963	No
56	IFIT2	ENSG00000119922.10			18440	0.081	0.2871	No
57	MVB12A	ENSG00000141971.13			18962	0.066	0.2765	No
58	PSME2	ENSG00000100911.16			19274	0.057	0.2708	No
59	PSMA3	ENSG00000100567.13			19401	0.054	0.2695	No
60	SP110	ENSG00000135899.17			19587	0.049	0.2666	No
61	SLC25A28	ENSG00000155287.11			19742	0.045	0.2643	No
62	CMTR1	ENSG00000137200.13			20027	0.039	0.2586	No
63	IRF2	ENSG00000168310.11			20158	0.035	0.2566	No
64	PROCR	ENSG00000101000.6			20786	0.018	0.2419	No
65	CXCL11	ENSG00000169248.13			20828	0.017	0.2415	No
66	RIPK2	ENSG00000104312.8			21192	0.007	0.2329	No
67	CNP	ENSG00000173786.17			22180	-0.018	0.2094	No
68	EIF2AK2	ENSG00000055332.18			22459	-0.025	0.2035	No
69	TRIM25	ENSG00000121060.18			22590	-0.028	0.2012	No
70	B2M	ENSG00000166710.20			22947	-0.038	0.1938	No
71	PSME1	ENSG00000092010.15			23061	-0.041	0.1924	No
72	PSMB9	ENSG00000240065.8			23347	-0.048	0.1870	No
73	SELL	ENSG00000188404.10			24840	-0.087	0.1535	No
74	NUB1	ENSG00000013374.16			25027	-0.093	0.1520	No
75	PNPT1	ENSG00000138035.15			25366	-0.101	0.1470	No
76	IFITM2	ENSG00000185201.16			25478	-0.105	0.1477	No
77	HLA-C	ENSG00000204525.16			25496	-0.105	0.1507	No
78	BST2	ENSG00000130303.13			26105	-0.124	0.1399	No
79	SAMD9L	ENSG00000177409.12			26142	-0.124	0.1431	No
80	TRIM14	ENSG00000106785.15			26324	-0.129	0.1429	No
81	NMI	ENSG00000123609.11			27198	-0.155	0.1267	No
82	TRIM26	ENSG00000234127.9			27466	-0.163	0.1255	No
83	ELF1	ENSG00000120690.16			27897	-0.176	0.1207	No
84	TRAFD1	ENSG00000135148.12			28382	-0.192	0.1152	No
85	WARS	ENSG00000140105.18			28765	-0.204	0.1125	No
86	CASP8	ENSG00000064012.21			30481	-0.259	0.0792	No
87	LAP3	ENSG00000002549.12			30778	-0.269	0.0807	No
88	CD47	ENSG00000196776.16			31817	-0.290	0.0649	No
89	CXCL10	ENSG00000169245.6			32700	-0.324	0.0540	No
90	LGALS3BP	ENSG00000108679.13			34698	-0.356	0.0169	No
91	TRIM5	ENSG00000132256.19			35146	-0.371	0.0181	No
92	TENT5A	ENSG00000112773.16			36817	-0.441	-0.0082	No
93	GBP4	ENSG00000162654.9			37113	-0.458	-0.0005	No
94	TDRD7	ENSG00000196116.8			38973	-0.598	-0.0264	No
95	IFI30	ENSG00000216490.4			39276	-0.621	-0.0135	No
96	TXNIP	ENSG00000265972.6			39777	-0.670	-0.0039	No
97	IL15	ENSG00000164136.17			41012	-1.156	0.0036	No

Fig 2: HALLMARK_INTERFERON_ALPHA_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INTERFERON_ALPHA_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INTERFERON_ALPHA_RESPONSE